Category: alcohols-buliding-blocks

Hajji, Mohamed published the artcileA water-soluble polysaccharide from Anethum graveolens seeds: Structural characterization, antioxidant activity and potential use as meat preservative, Formula: C6H12O6, the main research area is Anethum graveolens seed water soluble polysaccharide antioxidant meat preservative; Anethum graveolens; Antioxidant ability; Structural characterization; Turkey sausages preservation; Water-soluble polysaccharide.

A novel water-soluble polysaccharide named AGP1 was successfully isolated from seeds of Anethum graveolens by hot water extraction and further purified by DEAE-Sepharose chromatog. AGP1 has a relative mol. weight of 2.1 104 Da determined by Ultra-high-performance liquid chromatog. (UHPLC). The AGP1 characterization was investigated by chem. and instrumental anal. including gas chromatog. mass spectrometry (GC-MS), Fourier transform IR (FT-IR) spectroscopy and X-ray diffraction. Results showed that AGP1 was mainly composed of glucose, galactose, mannose and arabinose in a molar percent of 54.3, 23.8, 14.7 and 7.2, resp. The thermogravimetry anal. (TGA) and the differential scanning calorimetry (DSC) were used and showed that AGP1 has good thermal stability until 275°C. Moreover, the purified polysaccharide demonstrated an appreciable in vitro antioxidant potential. The addition of the AGP1, particularly at 0.3% (weight/weight), in turkey sausages instead of ascorbic acid, as preservative, reduced the lipid peroxidation, preserved the pH and color and improved the bacterial stability during cold storage at 4°C for 12 days. Overall, the results showed that the AGP1 deserves to be developed as functional and bioactive components for the food and nutraceutical industries.

International Journal of Biological Macromolecules published new progress about Anethum graveolens. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Weisany, Weria published the artcileEnhancement of the antifungal activity of thyme and dill essential oils against Colletotrichum nymphaeae by nano-encapsulation with copper NPs, Quality Control of 124-76-5, the main research area is Anethum Thymus leaf oil copper nanoparticle encapsulation antifungal Colletotrichum.

Nanotechnol. is a quickly growing field and have been actually used in a varied assortment of marketable products worldwide. Nanoencapsulation demonstrations the advantage of more efficient and targeted use of pesticides in an environmentally friendly way. Research and development in post-harvest nanotechnol. can help to preserve food freshness and quality and prevent diseases in a relatively safer way. In this regard, essential oils (EOs) represent promising agents for reducing food decay and development of pathogen microorganisms. The overall aim of the present study was to encapsulate Iranian thyme (Thymus daenensis L) and dill (Anethum graveolens L.) EOs in copper nanoparticles (NPs) and to evaluate their antifungal activity against the phytopathogen Colletotrichum nymphaeae. Encapsulation of thyme and dill EOs with copper NPs resulted effective in reducing the mycelium growth even by 90% after 9 days treatment. Furthermore a strong inhibitory effect on conidia germination of C. nymphaeae was observed SEM observations indicated that C. nymphaeae treated with EOs, copper NPs and encapsulated EOs, showed deformation in mycelial growth and hyphae twisting. In summary, these results showed that nano-encapsulation of EOs with NPs, using safe materials, increased the perspective of their effectiveness as new plant disease management strategies.

Industrial Crops and Products published new progress about Anethum graveolens. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lakra, Avinash Kant published the artcilePhysicochemical and functional characterization of mannan exopolysaccharide from Weissella confusa MD1 with bioactivities, Computed Properties of 59-23-4, the main research area is Weissella mannan exopolysaccharide antioxidant antibiofilm; Exopolysaccharide; Homopolysaccharide; Mannan; Weissella confusa.

The present study focused on production, optimization and characterization of exopolysaccharide (EPS) from Weissella confusa MD1. The purified EPS MD1 was also evaluated for in vitro biol. activities. The maximum yield of EPS (10.07 ± 0.32 g/L) was obtained with optimized culture conditions of 35°C at pH 6.5 for 36 h with 4% (w/v) galactose and 1% (w/v) ammonium nitrate supplemented in MRS broth. The crude EPS was purified with diethylamino ethanol-Sepharose Fast Flow column and Sephadex-G 75 column. The physicochem. and functional characterization of the EPS was done by high-performance thin-layer chromatog. (HPTLC), high-performance gel permeation chromatog. (HPGPC), Fourier transform IR (FTIR) spectroscopy, NMR (NMR), thermo gravimetric and differential scanning calorimetric (TG-DSC) anal., x-ray diffraction (XRD) and SEM (SEM). HPGPC anal. showed mol. weight of purified EPS MD1 as 2.909 KDa. Monosaccharide anal. showed that EPS was a novel mannan with mannose as the only monomeric unit present, suggesting EPS to be a homopolysaccharide containing → 6) α-Man p (1 → linkages. Microstructure studies by SEM showed MD1 EPS has globular and porous structure. The purified EPS MD1 exhibited higher thermal stability having degradation temperature around 267.74°C with melting enthalpy value (Δ H) of 337.7 J/g. The EPS showed promising antioxidant activities with excellent antibiofilm activity against Staphylococcus aureus, Listeria monocytogenes, Salmonella enterica and Salmonella typhi. These striking physicochem. characteristics features and bioactivities of EPS would serve as potential candidate in food processing industry to be used as food adjunct in foods with health benefits. This is the first study reporting a mannan homopolysaccharide from Weissella sp. to be structurally characterized.

International Journal of Biological Macromolecules published new progress about Antibiofilm agents. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Woolard, Katherine J. published the artcileDevelopment of small molecules that work cooperatively with ciprofloxacin to clear salmonella biofilms in a chronic gallbladder carriage model, Application of 2-(3,5-Dichlorophenyl)ethanol, the main research area is piperidine alkylation alc mesylation preparation antibiofilm salmonella gallbladder.

Salmonella enterica serovars cause millions of infections each year that result either in typhoid fever or salmonellosis. Among those serovars that cause typhoid fever, Salmonella enterica subspecies Typhi can form biofilms on gallstones in the gallbladders of acutely-infected patients, leading to chronic carriage of the bacterium. These biofilms are recalcitrant to antibiotic-mediated eradication, leading to chronic fecal shedding of the bacteria, which results in further disease transmission. Herein, we report the synthesis and anti-biofilm activity of a 55-member library of small mols. based upon a previously identified hit that both inhibits and disrupts S.Typhi and S. Typhimurium (a nontyphoidal model serovar for S. Typhi) biofilms. Lead compounds inhibit S. Typhimurium biofilm formation in vitro at sub-micromolar concentrations, and disperse biofilms with five-fold greater potentency than the parent compound Three of the most promising compounds demonstrated synergy with ciprofloxacin in a murine model of chronic Salmonella carriage. This work furthers the development of effective anti-biofilm agents as a promising therapeutic avenue for the eradication of typhoidal Salmonella.

European Journal of Medicinal Chemistry published new progress about Antibiofilm agents. 93427-13-5 belongs to class alcohols-buliding-blocks, name is 2-(3,5-Dichlorophenyl)ethanol, and the molecular formula is C8H8Cl2O, Application of 2-(3,5-Dichlorophenyl)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gargouri, Wafa published the artcileCoupling xylitol with remineralizing agents improves tooth protection against demineralization but reduces antibiofilm effect, Computed Properties of 64519-82-0, the main research area is antibiofilm xylitol tooth demineralization; CPP-ACP; Chewing gum; Dental plaque; Streptococcus mutans; Tooth demineralization; Xylitol.

To explore the efficiency of xylitol chewing gum enriched or not with remineralizing agents to protect tooth against cariogenic biofilm formation and demineralization. Six groups of chewing gums were prepared; Group 1: isomalt (1.8%), Group 2: casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) (3%) + isomalt (1.8%), Group 3: hydroxyapatite (HAP) (2.5%) + isomalt (1.8%), Group 4: xylitol (1.8%), Group 5: CPP-ACP (3%) + xylitol (1.8%) and Group 6: HAP (2.5%) + xylitol (1.8%). The antibiofilm properties of different chewing gum extracts using seven oral bacterial species including Streptococcus mutans, Streptococcus constellatus, Streptococcus Salivarius and Streptococcus oralis were explored via the crystal violet staining assay. The remineralizing effects of those products were assessed on thirty human permanent teeth, half-protected with varnish before chem. erosion and thermocycling process with chewing gum. Remineralization was evaluated using SEM and microscopic measurements on polarized light microscopy. The ratio R comparing the thickness between unvarnished and varnished sides was evaluated. While the min. biofilm inhibitory concentration (MBIC50) was low for xylitol alone compared to isomalt, it was inconsistent when enriched with remineralizing agents. The min. biofilm eradication concentration (MBEC50) was low for xylitol groups compared to isomalt, for all the studied strains. R was significantly lower in Group 1 and Group 2, while Group 6 showed the highest ratio. Xylitol chewing gums confirmed good antibiofilm properties and showed remineralized potential on eroded teeth. When xylitol is associated to CPP-ACP or HAP, antibiofilm activity decreased while remineralization of eroded teeth increased.

Microbial Pathogenesis published new progress about Antibiofilm agents. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Computed Properties of 64519-82-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yeo, Hyunki published the artcilePhotoinduced proton-transfer polymerization: a practical synthetic tool for soft lithography applications, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate), the main research area is photopolymerization proton transfer nanoimprint lithog base catalysis.

Proton-transfer photopolymerization through the thiol-epoxy “”click”” reaction is shown to be a versatile new method for the fabrication of micro- and nanosized polymeric patterns. In this approach, complexation of a guanidine base, diazabicycloundecene (DBU), with benzoylphenylpropionic acid (ketoprofen) generates a photolabile salt. Under illumination at a wavelength of 365 nm, the salt undergoes a photodecarboxylation reaction to release DBU as a base. The base-catalyzed ring opening reaction then creates cross-linked poly(β-hydroxyl thio-ether) patterns. The surface chem. of these patterns can be altered through alkylation of the thio-ether linkages. For example, a reaction with bromoacetic acid produces a hitherto unknown sulfonium/carboxylate-based zwitterionic motif that endows antibiofouling capacity to the micropatterns.

Journal of the American Chemical Society published new progress about Antifouling agents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kubisch, Christin published the artcileValorization of a Pyrolytic Aqueous Condensate and Its Main Components for L-Malic Acid Production with Aspergillus oryzae DSM 1863, Product Details of C4H6O5, the main research area is Aspergillus malic acid valorization pyrolytic aqueous condensate.

Pyrolytic aqueous condensate (PAC) might serve as a cost-effective substrate for microbial malic acid production, as it is an unused side stream of the fast pyrolysis of lignocellulosic biomass that contains acetol and acetate as potential carbon sources. In the present study, shake flask cultures were performed to evaluate the suitability of acetol and its combination with acetate as substrates for growth and L-malate production with the filamentous fungus Aspergillus oryzae. Acetol concentrations of up to 40 g/L were shown to be utilized for fungal growth. In combination with acetate, co-metabolization of both substrates for biomass and malate formation was observed, although the maximum tolerated acetol concentration decreased to 20 g/L. Furthermore, malate production on PAC detoxified by a combination of rotary evaporation, overliming and activated carbon treatment was studied. In shake flasks, cultivation using 100% PAC resulted in the production of 3.37 ± 0.61 g/L malate, which was considerably improved by pH adjustment up to 9.77 ± 0.55 g/L. A successful scale-up to 0.5-L bioreactors was conducted, achieving comparable yields and productivities to the shake flask cultures. Accordingly, fungal malate production using PAC was successfully demonstrated, paving the way for a bio-based production of the acid.

Fermentation published new progress about Aspergillus oryzae. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Product Details of C4H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Di Carluccio, Cristina published the artcileCharacterisation of the Dynamic Interactions between Complex N-Glycans and Human CD22, Related Products of alcohols-buliding-blocks, the main research area is autoimmune disease B cell malignancy CD22 N glycan; N-glycans; NMR spectroscopy; Siglecs; molecular recognition; sialic acids.

CD22 (Siglec-2) is a B-cell surface inhibitory protein capable of selectively recognising sialylated glycans, thus dampening autoimmune responses against self-antigens. Here we have characterised the dynamic recognition of complex-type N-glycans by human CD22 by means of orthogonal approaches including NMR spectroscopy, computational methods and biophys. assays. We provide new mol. insights into the binding mode of sialoglycans in complex with h-CD22, highlighting the role of the sialic acid galactose moieties in the recognition process, elucidating the conformational behavior of complex-type N-glycans bound to Siglec-2 and dissecting the formation of CD22 homo-oligomers on the B-cell surface. Our results could enable the development of addnl. therapeutics capable of modulating the activity of h-CD22 in autoimmune diseases and malignancies derived from B-cells.

ChemBioChem published new progress about Autoimmune disease. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Farkas, Erzsebet published the artcileRegioselective synthesis of galactosylated tri- and tetrasaccharides by use of β-galactosidase from Bacillus circulans, Product Details of C12H24O11, the main research area is oligosaccharide preparation regioselective transglycosylation catalyst galactosidase Bacillus circulans.

β-Galactosidase from Bacillus circulans (EC 3.2.1.23) catalyzes the transfer of galactose units to various glucose and galactose derivatives, forming β1→4 linkages. The synthesis of several biol. relevant tri- and tetrasaccharides {β-D-Galp-(1→4)-β-D-Galp-(1→4)-α,β-D-Glcp, β-D-Galp-(1→4)-α-D-Glcp-(1→4)-D-Glcp-ol/Manp-ol, β-D-Galp-(1→4)-α-D-Glcp-(1→6)-β-D-Fruf, β-D-Galp-(1→4)-α-D-Glcp-(1→2)-β-D-Fruf, β-D-Galp-(1→4)-α-D-Glcp-(1→2)-β-D-Fruf-(1→2)-β-D-Fruf, β-D-Galp-(1→4)-α-D-Glcp-(1→6)-[α-D-Glcp-(1→2)]-β-D-Fruf, β-D-Galp-(1→4)-α-D-Glcp-(1→2)-[α-D-Glcp-(1→6)]-β-D-Fruf, α-D-Galp-(1→6)-[β-D-Galp-(1→4)]-α-D-Glcp-(1→2)-β-D-Fruf, β-D-Galp-(1→4)-α-D-Galp-(1→6)-α-D-Glcp-(1→2)-β-D-Fruf} has been achieved in 11-59% yields by application of this enzyme.

Synthesis published new progress about Bacillus circulans. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Product Details of C12H24O11.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Becerra, Jaime-Andres published the artcileTechno-Economic Evaluation of d-Limonene and α-Pinene Separation from Citrus and Turpentine Oils, Quality Control of 124-76-5, the main research area is techno economic limonene alpha pinene Citrus turpentine oil.

The evaluation of the tech. and economic separation of the monoterpenes α-pinene and d-limonene from essential oils, carried out by computational simulation of the vacuum fractional distillation in continuous and batch mode from samples of turpentine and citrus oils, was developed using Aspen Plus software combined with estimations of operational expenses (OPEX) and capital expenses (CAPEX) based on the Guthrie method. The production of d-limonene and α-pinene with high purity from the essential oils is a tech. feasible process. From the economic point of view and based on the average annual import costs of turpentine and orange oils in Colombia, it was found that the selling prices of α-pinene and d-limonene obtained from the distillation module cost anal. depend on the daily production and can be minimized if essential oils are preliminary extracted from local industrial wastes.

Chemical Engineering & Technology published new progress about Batch distillation. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts