Category: alcohols-buliding-blocks

Ghanbariasad, Ali published the artcileNanoformulating Cinnamomum zeylanicum essential oil with an extreme effect on Leishmania tropica and Leishmania major, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Leishmania tropica major Cinnamomum zeylanicum essential oil nanoemulsion.

Major causatives for cutaneous leishmaniasis, the most common form of leishmaniasis, in the old world are Leishmania major and Leishmania tropica. Investigating the leishmanicidal effects of essential oils and preparing their nano/formulation is a promising approach for developing new green drugs. In this study, the ingredients of Cinnamomum zeylanicum essential oil were investigated using GC/MS anal., and its antioxidant effect was then evaluated using the DPPH assay. Moreover, the leishmanicidal effect of the essential oil against L. major and L. tropica was investigated; obtained half-maximal inhibitory concentrations (IC50)s were 16.53 and 7.56μg/mL. After that, a practical dosage form of C. zeylanicum, i.e., the nanoemulsion with a 52 ± 4 nm droplet size and a low droplet size distribution index (SPAN = 0.97), was prepared Interestingly, after treatment of both species with nanoemulsion, their viability was reduced to 0%. The prepared nanoformulation could be considered a potent anti-leishmanial agent for other species and in vivo studies.

Journal of Drug Delivery Science and Technology published new progress about Antioxidants. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Xue-Xia published the artcileStructural characterization and antioxidant activity of polysaccharides extracted from jujube using subcritical water, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Ziziphus polysaccharide antioxidant subcritical water.

Polysaccharides were extracted from jujube fruit using an efficient, optimized subcritical water extraction process. A maximum crude polysaccharide yield of 7.9% was obtained at an extraction temperature of 140°C and a time of 60 min. The crude polysaccharides extracted under these conditions were purified. Three polysaccharide fractions, ZP1, ZP2 and ZP3, were obtained and their structures were investigated. The three fractions were mainly composed of arabinose, galactose, glucose, mannose, rhamnose, and galacturonic acid. ZP3 was further investigated using methylation and NMR spectroscopy, and ZP3 comprised a main chain of (1 â†?4)-α-D-GalAp, (1 â†?2,4)-α-L-Rhap, with a (1 â†?4,6)-α-D-Galp branch. Assays of antioxidant activity showed that ZP3 exhibited a remarkable DPPH capacity and moderate hydroxyl radical scavenging ability, suggesting that it has potential applications as a natural antioxidant in foods and pharmaceuticals.

LWT–Food Science and Technology published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yener, Ismail published the artcileDetermination of antioxidant, cytotoxic, anticholinesterase, antiurease, antityrosinase, and antielastase activities and aroma, essential oil, fatty acid, phenolic, and terpenoid-phytosterol contents of Salvia poculata, Computed Properties of 124-76-5, the main research area is Salvia terpenoid antioxidant anticholinesterase.

In this study, the essential oil, aroma, fatty acid, terpeneoid and phenolic contents of Salvia poculata were investigated. Addnl., antioxidant, toxic-cytotoxic activities of essential oil and the ethanol extracts were determined Moreover, anticholinesterase, antiurease, antityrosinase and antielastase enzymes inhibition activities of the extracts were examined In GC-MS studies, germacrene D (20.07 %), caryophyllene (17.57 %) and tricosanoic acid (17.01 %) were determined as the major components for essential oil, aroma and fatty acid compositions, resp. Besides, according to the GC-MS and LC-MS/MS results, this species was determined to contain considerable amounts of ferruginol (9292.9 μg analyte/g extract) and rosmarinic acid (15612.08 μg analyte/g extract). In parallel with the high total phenolic and rosmarinic content of the species, its ethanol extract has a high antioxidant potential. It was determined that the species was not active against acetylcholinesterase enzyme, however, the root ethanol extract showed good activity (Inhibition%: 63.01 ± 1.12) against butyrylcholinesterase enzyme. All extracts of the species were found to have fairly high anti-urease activity (Inhibition%: 89.67 ± 0.72), however, all extracts of S. poculata showed moderate and similar activities in anti-tyrosinase and antielastase activity assays.

Industrial Crops and Products published new progress about Antioxidants. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ahmadi, Omid published the artcileIntensification and optimization of the process for thyme oil in water nanoemulsions preparation using subcritical water and xanthan gum, Name: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is thyme oil nanoemulsion subcritical water xanthan gum.

Intensified process based on subcritical water conditions (120°C and 1.5 atm, for 2 h) was utilized to prepare thyme oil in water (O/W) nanoemulsions. In this technique, water and xanthan gum, as green solvent and natural microbial emulsifier, were utilized. Results of gas chromatog. revealed that Thymol and Carvacrol were two main bioactive compounds of the extracted thyme oil. Effects of amounts of xanthan gum (0.05-0.25 g) and thyme essential oil (0.2-0.8 mL) on size of oil nanodroplets and polydispersity index (PDI) of the resulted nanoemulsions were evaluated using response surface methodol. Results demonstrated that the produced thyme O/W nanoemulsion by 0.242 mL thyme oil and 0.140 g xanthan gum had smallest average nanodroplet size (150 nm) and PDI (0.088). Furthermore, monodispersed and spherical in shape thyme oil nanodroplets were provided in the nanoemulsion using these optimal conditions with zeta potential value of -10.1 mV and antioxidant activity of 17.4%. Results also indicated that this prepared nanoemulsion had high fungicidal and bactericidal activities toward Penicillium digitatum and Escherichia coli, resp.

Zeitschrift fuer Physikalische Chemie (Berlin, Germany) published new progress about Antioxidants. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Name: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, Huan published the artcileExtraction optimization and effects of extraction methods on the chemical structures and antioxidant activities of polysaccharides from snow chrysanthemum (Coreopsis tinctoria), Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is coreopsis polysaccharide uronic acid monosaccharide antioxidant UAE MAE; Coreopsis tinctoria; antioxidant activity; chemical structure; extraction optimization; polysaccharide.

In order to explore snow chrysanthemum polysaccharides (SCPs) as functional food ingredients and natural antioxidants for industrial applications, both microwave-assisted extraction (MAE) and ultrasonic-assisted extraction (UAE) were firstly optimized for the extraction of SCPs. Furthermore, the effects of conventional hot water extraction, UAE, and MAE on the chem. structures and antioxidant activities of SCPs were investigated. The maximum extraction yields of SCPs extracted by UAE (4.13 ± 0.24%) and MAE (4.26 ± 0.21%) were achieved at the optimized extraction parameters as follows: ultrasound amplitude (68%) and microwave power (500 W), ultrasound extraction time (21 min) and microwave extraction time (6.5 min), and ratio of liquid to raw material (42.0 mL/g for UAE and 59.0 mL/g for MAE). In addition, different extraction methods significantly affected the contents of uronic acids, the mol. weights, the molar ratio of constituent monosaccharides, and the degree of esterification of SCPs. SCPs exhibited remarkable DPPH (IC50 = 1.702 mg/mL), ABTS (IC50 = 1.121 mg/mL), and nitric oxide (IC50 = 0.277 mg/mL) radical scavenging activities, as well as reducing power (= 80.17 ± 4.8μg Trolox/mg), which suggested that SCPs might be one of the major contributors toward the antioxidant activities of snow chrysanthemum tea. The high antioxidant activities (DPPH, IC50 = 0.693 mg/mL; ABTS, IC50 = 0.299 mg/mL; nitric oxide, IC50 = 0.105 mg/mL; and reducing power, 127.79 ± 2.57μg Trolox/mg) observed in SCP-M extracted by the MAE method might be partially attributed to its low mol. weight and high content of unmethylated galacturonic acids. Results suggested that the MAE method could be an efficient technique for the extraction of SCPs with high antioxidant activity, and SCPs could be further explored as natural antioxidants for industrial application.

Polymers (Basel, Switzerland) published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cai, Liangliang published the artcileOptimization of extraction of polysaccharide from dandelion root by response surface methodology: Structural characterization and antioxidant activity, Related Products of alcohols-buliding-blocks, the main research area is polysaccharide dandelion root antioxidant activity; Antioxidant activity; Dandelion root polysaccharides; Response surface methodology.

In this study, response surface methodol. (RSM) was used to optimize the extraction parameters of dandelion root polysaccharide (DRP). Two novel polysaccharides (DRP-2b, DRP-3a) were isolated from dandelion root by graded ethanol precipitation and column chromatog. Structural analyses indicated that DRP-2b, with a mol. weight of 31.8 kDa, was composed of rhamnose, glucuronic acid, glucose, galactose and arabinose, whereas DRP-3a, with a mol. weight of 6.72 kDa, was composed of rhamnose, glucose, galactose and arabinose. The backbones of DRP-2b and DRP-3a were mainly composed of (1 �5)-linked-a-D-Ara and (1 �6)-linked-a-D-Glc, resp. In addition, the antioxidant activities and protective effects against H2O2-induced damage in hepatic L02 cells were evaluated. DRP-3a exhibited higher radical scavenging activity than DRP-2b against the DPPH, hydroxyl and superoxide anions. Furthermore, DRP-3a exhibited strong protective effects against H2O2-induced damage in hepatic L02 cells. Thus, DRP-3a could be used as a potential antioxidant in medicine or as a functional food.

International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Yancong published the artcileZinc(II) and manganese(II) complexes with 1,3-bis(1-allylbenzimidazol-2-yl)-2-oxapropane: synthesis, crystal structures, antioxidant activities and DNA-binding properties, Computed Properties of 110-99-6, the main research area is zinc manganese allylbenzimidazolyloxapropane complex preparation crystal structure antioxidant; DNA interaction zinc manganese allylbenzimidazolyloxapropane complex.

Two new zinc(II) and manganese(II) complexes with the ligand 1,3-bis(1-allylbenzimidazol-2-yl)-2-oxopropane (aobb), with composition [Zn(aobb)2](pic)2·DMF·CH3OH and [Mn(aobb)(DMF)2(H2O)](pic)2 (pic = picrate; DMF = N,N-dimethylformamide), were synthesized and characterized by elemental anal., elec. conductivities, x-ray single-crystal diffraction, IR, and UV-visible spectra. Single-crystal x-ray revealed that Zn(II) and Mn(II) centers are both located in the six-coordinate distorted octahedral geometry. The DNA-binding modes of the ligand and the complexes were studied by electronic absorption titration, competitive binding with ethidium bromide and viscosity measurements. The exptl. evidence indicated the ligand and complexes interact with calf thymus DNA through intercalation. The binding strength follows the order >>aobb. Addnl., displays potential superoxide dismutase activity in vitro studies.

Journal of Coordination Chemistry published new progress about Antioxidants. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Computed Properties of 110-99-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Fan published the artcileCombined toxic effects of dioxin-like PCB77 with Fe-based nanoparticles in earthworm Eisenia fetida, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is Eisenia iron PCB77 dioxin nanoparticle toxicity; PCBs; Physiological and morphological change; Synergistic effect; Vermiremediation; nZVI.

Iron-based nanomaterials hold promise for in situ remediation of persistent halogenated contaminants such as dioxin-like polychlorinated biphenyls, however, their complex interactions and joint toxicity toward beneficial soil biol. functions remain unknown. This study examined the effects of nano-zero valent iron (nZVI) on the physiol. and morphol. changes, on the bioaccumulation of co-existed dioxin-like 3,3,4,4-tetrachloro-biphenyls (PCB77), and the joint toxicity of nZVI and PCB77 in earthworms Eisenia fetida. An orthogonally designed experiment was conducted through the exposure of E. fetida to the combined and sep. nZVI and PCB77 at various concentrations in soil for 28 days (nZVI at the levels of g-Fe/kg-soil and PCB77 at the levels of mg-PCB/kg-soil). Indicated that both nZVI and PCB77 inhibited the growth and reproduction of earthworms, and the combined exposure resulted in a synergistic effect. The addition of 10 g/kg nZVI decreased the contents of PCB77 and significantly increased the accumulation of PCB77 to a level ranging 14-97 mg/kg in earthworms in a nZVI dose dependent manner. The observed synergism might relate to the aggravated damage of earthworm epidermis in the presence of nZVI. PCB77 and nZVI at their corresponding high levels (10 mg/kg and 10 g/kg) induced oxidative stress and lipid peroxidation in the earthworms through the increased levels of reactive oxygen species and the subsequent inhibition of antioxidant enzymes including superoxide dismutase and catalase. Further metabolomics analyses revealed that the normal glutamic acid metabolism and tricarboxylic acid cycle were disturbed in earthworms exposed to the combined treatment of 10 mg/kg PCB77 and 10 g/kg nZVI. Our findings suggested that earthworms as a sentinel species could be readily employed in toxicity and tolerance studies to succeed the safe applications of nZVI and interestingly earthworms themselves also hold promise for vermiremediation owing to the high bioaccumulation potential of PCBs from contaminated soils.

Science of the Total Environment published new progress about Antioxidants. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cautela, Domenico published the artcileCharacterization of essential oil recovered from fennel horticultural wastes, Application In Synthesis of 124-76-5, the main research area is fennel horticultural waste essential oil; antioxidant activity; essential oil; fennel wastes; phytochemical recovery.

Fennel crop has been traditionally used as spice in cooking and fragrances, and in folk medicine for its spectrum of useful properties. Mediterranean is the elective natural cultivation area for this plant with Italy being a leader producer. A limit of this production is due to the high amount of wastes derived still rich of phytochems., which are usually underused. Hence, the extraction and characterization of essential oil from residues of fennel horticultural market was investigated to understand the potential profit of their recycling. Forty-eight compounds resulted for fennel oil waste, analyzed by GC-FID-MS, with the most abundant among components was anethole. Other constituents contributing to fennel flavor were the monoterpenes limonene and nerol. The exploitation of this oil as a good source of bioactive compounds was assessed by means of its antioxidant power measured with DPPH test.

Natural Product Research published new progress about Antioxidants. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application In Synthesis of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kiferle, Claudia published the artcileEffect of Iodine treatments on Ocimum basilicum L.: Biofortification, phenolics production and essential oil composition, Formula: C10H18O, the main research area is Ocimum iodine essential oil biofortification phenolics.

Iodine biofortification has been gaining interest in recent years as a sustainable and innovative approach to eradicate iodine deficiency disorders. Studying the impact of iodine biofortification on plant phenotype, biochem. and physiol. parameters is crucial to leverage the expertise and best practices for the agro-food industry and human health. The aim of this study was to evaluate iodine biofortification on the main quant. and qual. traits of basil (Ocimum basilicum L.) plants cultivated both in open field and in growth chamber. The impact of KI and KIO3 treatments was evaluated on biomass production, as well as on the synthesis of phenolic compounds, especially rosmarinic acid and other caffeic acid derivatives, and on the essential oil (EO) composition These compounds are typically accumulated in basil leaves and strongly contribute to the plant nutraceutical value and aroma. In open field, the use of increasing concentrations of both iodine salts gradually enhanced iodine accumulation in leaves, also determining an increase of the antioxidant power, total phenolics, rosmarinic acid and cinnamic acid accumulation. The composition of EO was only slightly affected by the treatments, as all the samples were characterized by a linalool chemotype and a minor alteration in their relative content was observed A growth chamber experiment was performed to test EO variation in controlled conditions, broadening the range of iodine concentrations In this case, plant chemotype was significantly affected by the treatments and large EO variability was observed, suggesting that iodine form and concentration can potentially influence the EO composition but that in open field this effect is overcome by environmental factors.

PLoS One published new progress about Antioxidants. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Formula: C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts