Category: alcohols-buliding-blocks

Nadian, Narges published the artcileTextural and sensory characteristics of sugar-free biscuit formulated with quinoa flour, isomalt, and maltodextrin, Application In Synthesis of 64519-82-0, the main research area is optimization quinoa response surface method sugar free biscuit; optimization; quinoa; response surface method; sugar ‐free biscuit.

A low-calorie biscuit formulation containing quinoa flour (cultivars TTKK), isomalt, and maltodextrin was optimized using response surface methodol. Optimized samples were evaluated in terms of total phenolic compounds (TPC), sensory properties, and nutritional value while samples containing only wheat flour (Pishgam var.) and sucrose were used as control. Morphol. of isolated starch from quinoa was also investigated. The results showed that with increasing amounts of quinoa, isomalt, and maltodextrin Δ E and Browning index increased, whereas hardness and L values decreased. The formulation containing 25% quinoa flour, 3.5% maltodextrin, and 10% isomalt was found to be optimal with an overall desirability value of 0.95. The sensory evaluation showed that replacement of wheat flour with 25 g/100 g quinoa flour in biscuits was acceptable. TPC of the optimal biscuit (1,180.34 ± 0.02 μg GAE/g) was higher than that of the control sample (729.95 ± 0.007 μg GAE/g). In addition, the optimized biscuit had more protein (8.36 ± 0.035%) and dietary fiber (2.14± 0.035%) content compared with the control sample (7.01 ± 0.007% and 1.66 ± 0.028%, resp.). The consumption of 100 g of optimized quinoa biscuits supplies the daily requirement of Fe, Mg, Ca, and Zn at 2.43%, 44.81%, 19.46% and 1.12%, resp.

Food Science & Nutrition (Hoboken, NJ, United States) published new progress about Biscuits. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Application In Synthesis of 64519-82-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shapira, Anna published the artcileTandem Mass Spectrometric Quantification of 93 Terpenoids in Cannabis Using Static Headspace Injections, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Cannabis terpenoid GC quadrupole tandem MS.

The therapeutic effect of Cannabis largely depends on the content of its pharmacol. active secondary metabolites, mainly phytocannabinoids, flavonoids, and terpenoids. Recent studies suggest there are therapeutic effects of specific terpenoids as well as synergistic effects with other active compounds in the plant. Although Cannabis contains an overwhelming milieu of terpenoids, only a limited number are currently reported and used for metabolic anal. of Cannabis chemovars. In this study, we report the development and validation of a method for simultaneous quantification of 93 terpenoids in Cannabis air-dried inflorescences and extracts This method employs the full evaporation technique via a static headspace sampler, followed by gas chromatog.-mass spectrometry (SHS-GC/MS/MS). In the validation process, spiked terpenoids were quantified with acceptable repeatability, reproducibility, sensitivity, and accuracy. Three medical Cannabis chemovars were used to study the effect of sample preparation and extraction methods on terpenoid profiles. This method was further applied for studying the terpenoid profiles of 16 different chemovars acquired at different dates. Our results demonstrate that sample preparation methods may significantly impact the chem. fingerprint compared to the nontreated Cannabis. This emphasizes the importance of performing SHS extraction in order to study the natural terpenoid contents of chemovars. We also concluded that most inflorescences expressed relatively unique terpenoid profiles for the most pronounced terpenoids, even when sampled at different dates, although absolute concentrations may vary due to aging. The suggested method offers an ideal tool for terpenoid profiling of Cannabis and sets the scene for more comprehensive works in the future.

Analytical Chemistry (Washington, DC, United States) published new progress about Cannabis. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Katagiri, Takayuki published the artcileTrivalent metal ions promote the malic enzyme-catalyzed building of carbon-carbon bonds from CO2 and pyruvate, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is malic enzyme carbon dioxide pyruvate aluminum iron ion carboxylation.

Malic enzyme (ME) from chicken liver (EC 1.1.1.40) is an enzyme that catalyzes the decarboxylation of malate into pyruvate and CO2 and the reverse reaction that introduces CO2 as a carboxy-group to pyruvate to form malate via oxaloacetate in the presence of natural co-enzyme NADP+/NADPH. Thus, ME is an attractive biocatalyst for building carbon-carbon bonds through the carboxylation of pyruvate with CO2. Since ME mainly catalyzes the decarboxylation of malate to produce pyruvate via oxaloacetate, it is necessary to devise ways to promote the carboxylation of pyruvate with CO2 to produce oxaloacetate based on the building of carbon-carbon bonds. Enhancing the carboxylation of pyruvate by the addition of metal ions with CO2 and using ME as a catalyst will lead to new insight into biocatalytic CO2 utilization research. The effect of adding divalent and trivalent metal ions to promote the ME-catalyzed building of carbon-carbon bonds through the carboxylation of pyruvate with CO2 was investigated. Specifically, it was found for the first time that the addition of trivalent aluminum and iron ions accelerates ME-catalyzed carboxylation of pyruvate with CO2. Moreover, it was found that a high concentration of aluminum ions (>100μM) and a low concentration of iron ions (<10μM) promote the ME-catalyzed carboxylation of pyruvate with CO2. New Journal of Chemistry published new progress about C-C bond. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Minwei published the artcileHS-SPME-GC-MS/olfactometry combined with chemometrics to assess the impact of germination on flavor attributes of chickpea, lentil, and yellow pea flours, Application of n-Octanol, the main research area is germination chickpea lentil pea; (E,E)-2,4-decadienal (PubChemCID: 5283349); (E,E)-2,4-nonadienal (PubChemCID: 5283339); 1-Hexanol (PubChemCID: 8103); 2-Pentyl-furan (PubChemCID: 19620); 3-Methyl-1-butanol (PubChemCID: 31260); Beany flavor; Chemometric; Germination; Gluten-free; Hexanal; Hexanal (PubChemCID: 6184); Pulse.

In this study, volatile component changes of germinated chickpea, lentil, and yellow pea flours over the course of 6 days germination were characterized by HS-SPME-GC-MS/O. In total, 124 volatile components were identified involving 19 odor active components being recorded by GC-O exclusively. Principal component anal. (PCA) and hierarchical cluster anal. (HCA) revealed that lentil and yellow pea flours had the similar aromatic attributes, while the decrease of beany flavor compounds along with the occurrence of unpleasant flavors was detected in chickpea flours upon germination. Six beany flavor markers, including hexanal, (E,E)-2,4-nonadienal, (E,E)-2,4-decadienal, 3-methyl-1-butanol, 1-hexanol, and 2-pentyl-furan, were employed to quantify beany flavor formation in the flours over the course of germination. The results suggested that no significant beany flavor formation or mitigation was appeared after 1 day of germination. The findings are crucial for tailing pulse germination process to enhance the macronutrients without increasing undesirable beany flavor.

Food Chemistry published new progress about Chickpea. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sharma, Manish published the artcileA significant increase in rhizosheath carboxylates and greater specific root length in response to terminal drought is associated with greater relative phosphorus acquisition in chickpea, HPLC of Formula: 97-67-6, the main research area is Cicer arietinum rhizosheath carboxylate root drought phosphorus.

We investigated the effects of water stress under low phosphorus (P) supply on P-acquisition by chickpea, and identified a genotype with faster relative growth and P-acquisition rates. We grew four genotypes in pots filled with a sand and soil mixture with a low P availability in a glasshouse. Plants were either well-watered or water-stressed, imposed at the reproductive stage. Plants were harvested when water-stressed plants fully closed their stomata. For all four genotypes, water stress reduced shoot and root growth, root mass ratio, and shoot P content, while it increased specific root length (except in ICC 456), water-use efficiency and the amount of rhizosheath carboxylates per g root dry weight A faster relative shoot P-acquisition rate in ICC 2884 was associated with a greater specific root length, a smaller mean root diameter and a greater increase in the amount of rhizosheath carboxylates in response to water stress under low P supply. Interestingly, under water stress ICC 2884 also maintained a similar physiol. P-use efficiency to that of the well-watered plants. ICC 2884 is recommended as a parental genotype in chickpea breeding programs to develop cultivars for low-P and terminal drought environments.

Plant and Soil published new progress about Chickpea. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, HPLC of Formula: 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Khatouri, M. published the artcileSol/gel transition of oil/water microemulsions controlled by surface grafted triblock copolymer dodecyl-PEO227-dodecyl: molecular dynamics simulations with experimentally validated interaction potential, Recommanded Product: n-Octanol, the main research area is soluble gel transition microemulsion copolymer mol dynamic simulation.

We studied a large range of identical spherical oil/water microemulsion (O/W-MI) volume fractions. The O/W-MIs are stabilized by cetylpyridinium chloride ionic surfactant (CpCl) and octanol cosurfactant and dispersed in salt water. We grafted different numbers of dodecyl-(polyEthylene oxide)227-dodecyl triblock copolymer that we note (n(D-PEO227-D)), where n varies from 0 to 12. We accomplished the grafting process by replacing a small amount of CpCl and octanol with the appropriate n(D-PEO227-D). The aim is to determine the interaction/structure relationship of the covered microemulsions. Precisely, we are interested in a quant. investigation of the influence of volume fraction Φ, temperature (T), and n(D-PEO227-D) on the microemulsion sol/gel transition. To this end, we first study the uncoated microemulsion structure depending only on Φ. Second, we determine the coated microemulsions structure as a function of n(D-PEO227-D) for different Φ. Third, we examine the effect of temperature on the uncoated and coated microemulsion. We show that the sol/gel transition is controlled by the three main parameters, Φ, T, and n(D-PEO227-D). Accordingly, the uncoated microemulsion sol/gel transition, at ambient temperature, occurred for Φ ≃ 33.65%. By increasing Φ, the O/W-MIs show a glass state, which occurs, along with the gel state, at Φ ≃ 37% and arises clearly at Φ ≃ 60%. The coated O/W-MI sol/gel transition is found to be linearly dependent on n(D-PEO227-D) and takes place for Φ ≃ 26.5% for n(D-PEO227-D) = 12. Ordinarily, the decrease in temperature leads to gel formation of microemulsions for low Φ. Addnl., in this work, we found that the gelation temperature increases linearly with n(D-PEO227-D). Thus, the parameter n(D-PEO227-D) can control the sol/gel transition of the O/W-MIs at ambient temperature and moderate Φ.

RSC Advances published new progress about Clusters. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yoshimura, Yukihiro published the artcileRaman investigation on the local structure of alcohols in 1-butyl-3-methylimidazolium tetrafluoroborate, Application In Synthesis of 111-87-5, the main research area is alc ionic liquid hydrogen bond cluster Raman spectra conformation.

In this study, we investigated the evolution of the local structure of a series of primary alcs. from methanol to octanol in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]) as a function of alc. concentration using Raman spectroscopy, with the aim of gaining more insight into the fundamentals of the compelling ionic liquid-mol. solvent interactions at mol. level. The Raman spectra revealed the presence of various types of O-H species in the mixtures, with the major fractions at low alc. concentration corresponding to monomers, which indicates that most of the alc. mols. are isolated from each other. A plausible picture for the changes in the local structures of alc. mols. loosely confined in the [bmim][BF4] matrix is presented, which suggests the occurrence of conformational changes in the bmim+ cation and the alc. mols. This observation may indicate a unique evolution of the local structure of alc. clusters formed in the ionic liquid

Journal of Molecular Liquids published new progress about Clusters. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yoshimura, Yukihiro published the artcileAn insight into the filling of the nanoheterogeneous structures of1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide by primary alcohols, COA of Formula: C8H18O, the main research area is ionic liquid alc hydrogen bond cluster Raman spectra conformation.

Mixtures of ionic liquids (ILs) with mol. cosolvents are attracting increased attention for the development of their technol. applications. As a result, understanding the interaction between the heterogeneous structure of ILs and mol. cosolvents at a microscopic level with the aim of fine-tuning the properties of ILs is of utmost importance. In this study, the local structure of the IL 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide ([bmim][TFSA]) in a series of mixtures of primary alc. (from methanol to 1-dodecanol) is investigated as a function of alc. concentration by Raman spectroscopy, providing a unique picture of the evolution of the local structure of alc. clusters formed in [bmim][TFSA]. The Raman spectra reveal the presence of various types of O-H species in the [bmim][TFSA]-alc. mixtures, with the major fractions corresponding to monomers at lower alc. concentrations Presented in this study is a plausible mechanism for the filling of the nanoheterogeneous structures of the [bmim][TFSA] matrix by alc. mols., revealing the occurrence of conformational changes in the bmim+ cation and TFSA- anion, which involves an increase of the population of the gauche and transoid conformers with alc. concentration Interestingly, the results show that the local structures of bmim+ and TFSA- cooperatively change along with the conformational change in the alc. mols. toward a smaller total volume

Journal of Molecular Liquids published new progress about Clusters. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, COA of Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sun, Tong published the artcileFreezing of Dilute Aqueous-Alcohol Nanodroplets: The Effect of Molecular Structure, Category: alcohols-buliding-blocks, the main research area is freezing alc nanodroplet mol structure property relationship.

We investigate vapor-liquid nucleation and subsequent freezing of aqueous-alc. nanodroplets containing 1-pentanol, 1-hexanol, and their 3-isomers. The aerosols are produced in a supersonic nozzle, where condensation and freezing are characterized by static pressure and Fourier transform IR (FTIR) spectroscopy measurements. At fixed water concentrations, the presence of alc. enables particle formation at higher temperatures since both the equilibrium vapor pressure above the critical clusters and the cluster interfacial free energy are decreased relative to the pure water case. The disappearance of a small free OH peak, observed for pure water droplets, when alcs. are added and shifts in the CH peaks as a function of alc. chain length reveal varying surface partitioning preferences of the alcs. Changes in the FTIR spectra during freezing, as well as changes in the ice component derived from self-modeling curve resolution anal., show that 1-hexanol and 1-pentanol perturb freezing less than their branched isomers do. This behavior may reflect the mol. footprints of the alcs., the available surface area of the droplets, and not only alc. solubility The presence of alcs. also lowers the freezing temperature relative to that of pure water, but when there is clear evidence for the formation of ice, the ice nucleation rates change by less than a factor of ~2-3 for all cases studied.

Journal of Physical Chemistry B published new progress about Clusters. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Quodbach, Julian published the artcileCompaction behavior of isomalt after roll compaction, Name: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is galenIQ 801 tablet roll compaction dry granulation flowability friability.

The suitability of the new isomalt grade galenIQ 801 for dry granulation and following tableting is evaluated in this study. Isomalt alone, as well as a blend of equal parts with dibasic calcium phosphate, is roll compacted and tableted. Particle size distribution and flowability of the granules and friability and disintegration time of the tablets are determined Tensile strength of tablets is related to the specific compaction force during roll compaction and the tableting force. In all cases, the tensile strength increases with raising tableting forces. The specific compaction force has a different influence. For isomalt alone the tensile strength is highest for tablets made from granules prepared at 2 kN/cm and 6 kN/cm and decreases at higher values, i.e., >10 kN/cm. Tensile strength of the blend tablets is almost one third lower compared to the strongest tablets of pure isomalt. Friability of pure isomalt tablets is above the limit. Disintegration time is longest when the tensile strength is at its maximum and decreases with higher porosity and lower tensile strengths. Isomalt proves to be suitable for tableting after roll compaction. Even though the capacity as a binder might not be as high as of other excipients, it is a further alternative for the formulation scientist.

Pharmaceutics published new progress about Cohesion. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Name: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts