Category: alcohols-buliding-blocks

Wang, Ruihua published the artcileThe bisphenol F and bisphenol S and cardiovascular disease: results from NHANES 2013-2016, Quality Control of 80-09-1, the publication is Environmental Sciences Europe (2022), 34(1), 4, database is CAplus.

Bisphenol F (BPF) and bisphenol S (BPS) have replaced bisphenol A (BPA) in the manufacturing of products containing polycarbonates and epoxy resins; however, the effects of these substitutes on the risk of cardiovascular disease (CVD), including congestive heart failure, coronary heart disease, angina pectoris, heart attack, and stroke, have not been assessed. To examine the association of urinary BPS and BPF with CVD risk in a U.S. representative U.S. population. Cross-sectional data from 1267 participants aged 20-80 years from the 2013-2016 National Health and Nutrition Examination Survey (NHANES) were analyzed. Survey-weighted multiple logistic regression was used to assess the association between BPA, BPF, BPS and CVD. The Bayesian kernel machine regression (BKMR) model was applied to assess the mixture effect. A total of 138 patients with CVD were identified. After adjusting for potential confounding factors, the T3 tertile concentration of BPS increased the risk of total CVD (OR: 1.99, 95% CI 1.16-3.40). When stratified by age, we found that BPS increased the risk of CVD in the 50-80 age group (OR: 1.40, 95% CI 1.05-1.87). BPS was pos. associated with the risk of coronary heart disease, and the T3 tertile concentration of BPS increased the coronary heart disease risk by 2.22 times (95% CI 1.04-4.74). No significant association was observed between BPF and CVD. Although the BKMR model did not identify the mixed exposure effect of BPS, the risk of CVD increased with increasing compound concentration Our results suggest that BPS may increase the risk of total CVD and coronary heart disease in the US population, and prospective studies are needed to confirm the results.

Environmental Sciences Europe published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C19H14O2, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Burba, Christopher M. published the artcileThe Effect of Fluorinated Solvents on the Physicochemical Properties, Ionic Association, and Free Volume of a Prototypical Solvate Ionic Liquid, Safety of 2,2′-((Perfluoroethane-1,2-diyl)bis(oxy))bis(2,2-difluoroethanol), the publication is ChemPhysChem (2022), 23(4), e202100548, database is CAplus and MEDLINE.

Solvate ionic liquid (SIL) synthesis and properties depend on a delicate balancing of cation-solvent and cation-anion interactions to produce materials containing only cation-solvent complexes and solvent-separated anions. Most SILs meeting these characteristics fall within the paradigm of oligomeric ethylene oxides (e.g. glymes and glycols) and lithium salts. Targeted functionalization of solvent mols. to achieve desired properties is a relatively unexplored avenue of research. Fluorinated solvents have significantly different elec. charge distributions compared to their nonfluorinated analogs. We test the impact of solvent fluorination for a SIL created from equimolar mixtures of lithium bis(trifluoromethylsulfonyl)imide (LiNTf₂) and triethylene glycol (TEG), hereafter [(TEG)₁Li]NTf₂. In the first experiment, TEG is partially substituted with 2,2,4,4,5,5,7,7-octafluoro-3,6-dioxaoctane-1,8-diol (FTEG). This leads to a precipitous decrease in ionic conductivity and larger quantities of ionically-associated Li(NTf₂)₂^– species, as detected with vibrational spectroscopy. These observations suggest FTEG does not readily coordinate Li⁺ ions in a manner analogous to TEG. Computational studies reinforce this conclusion. Relative complex cation stabilities are ranked as [(FTEG)₁Li]⁺ > [(TEG)₁Li]⁺. A second experiment adds FTEG as a diluent to [(TEG)₁Li]NTf₂. This places FTEG and TEG in competition to coordinate a limited number of Li⁺ ions. The resulting mixtures exhibit conductivity enhancement over the parent SIL and minimal changes in ion speciation due to the poor Li⁺ binding by FTEG compared to TEG. Positron annihilation lifetime spectroscopic studies point to increased amounts of free volume upon dilution of FTEG. This likely explains the origin of the conductivity and viscosity enhancements.

ChemPhysChem published new progress about 129301-42-4. 129301-42-4 belongs to alcohols-buliding-blocks, auxiliary class Fluoride,Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2,2′-((Perfluoroethane-1,2-diyl)bis(oxy))bis(2,2-difluoroethanol), and the molecular formula is C6H6F8O4, Safety of 2,2′-((Perfluoroethane-1,2-diyl)bis(oxy))bis(2,2-difluoroethanol).

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zheng, Ran published the artcileMicrowave-assisted efficient synthesis of 3-substituted bis-isoxazole ether bearing 2-chloro-3-pyridyl via 1,3-dipolar cycloaddition, Recommanded Product: 3-(2-Chlorophenyl)-5-isoxazolemethanol, the publication is Molecular Diversity (2020), 24(2), 423-435, database is CAplus and MEDLINE.

An efficient strategy for synthesizing of 3-substituted bis-isoxazole ether bearing 2-chloro-3-pyridyl under microwave radiation was reported. The reactive regioselectivity was improved by changing mainly the solvent and acid-binding agent. 3-(2-Chloropyridin-3-yl)-5-(((3-substituted Ph isoxazol-5-yl)methoxy)methyl)isoxazoles were synthesized in 31-92% yields and were characterized by FT-IR, HRMS, ¹H and ¹³C NMR spectroscopy. The single crystal of 3-(2-chloropyridin-3-yl)-5-(((3-(p-tolyl)isoxazol-5-yl)methoxy)methyl)isoxazole was obtained and the structure of compound was also determined by X-ray diffraction technique. Weak intra- and intermol. C-H···O interactions and a C-H···π interaction link mols. into a three-dimensional network. The results showed that the synthesized compounds belonged to triclinic system, and their regioselectivity depended on the solvent and acid-binding agent. The merits of this method include the environmentally friendly, efficient, simple operation, and higher regional selectivity. An efficient synthesis of 3-substituted bis-isoxazole ethers was developed via 1,3-dipolar cycloaddition reaction starting from 3-substituted phenyl-5-((prop-2-yn-1-yloxy)methyl)isoxazoles and (Z)-2-chloro-N-hydroxynicotinimidoyl chloride using NaHCO₃ as an acid-binding agent in THF solvent-dissolved trace water under catalyst-free microwave-assisted conditions.

Molecular Diversity published new progress about 438565-33-4. 438565-33-4 belongs to alcohols-buliding-blocks, auxiliary class Isoxazole,Chloride,Benzene,Alcohol, name is 3-(2-Chlorophenyl)-5-isoxazolemethanol, and the molecular formula is C9H4F6O, Recommanded Product: 3-(2-Chlorophenyl)-5-isoxazolemethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lu, Xinli published the artcileDetermination of 2-keto-L-gulonic acid in fermented broth by flow injection chemiluminescence using potassium permanganate-rhodamine B system, Product Details of C6H10O7, the publication is Asian Journal of Chemistry (2013), 25(18), 10179-10181, database is CAplus.

In this paper, a flow injection-chemiluminescence (FI-CL) was presented for the determination of 2-keto-L-gulonic acid in fermented broth. This method was based on enhance effect of 2-keto-L-gulonic acid on the chemiluminescence reaction between rhodamine B and potassium permanganate in acid medium. The optimized exptl. conditions were evaluated. Under optimum conditions, calibration curve over the range of 0.2-60 mg L^-1 was obtained. The detection limit of this method was 0.04 mg L^-1. The relative standard deviation was 3.7 % for 2.0 mg L^-1 2-keto-L-gulonic acid. The method validation has been compared vs. HPLC method for determination of 2-keto-L-gulonic acid in fermented broth.

Asian Journal of Chemistry published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Product Details of C6H10O7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Aki, Sudhir N. V. K. published the artcileGeneration of Xanthenium and 9-Phenylxanthenium Carbocations in Subcritical Water and Reactivity with Amylamine, Product Details of C19H14O2, the publication is Journal of Physical Chemistry A (2001), 105(34), 8046-8052, database is CAplus.

The ability of subcritical water to support ionic chem. is evident from the successful generation of 9-R-xanthenium (R = H and C₆H₅) carbocations at temperatures up to 330° from their resp. alc. precursors using laser flash photolysis. The intrinsic carbocation decay in the solvent was found to follow simple Arrhenius behavior at all temperatures, from ambient up to 330 °C. In addition, we determined the bimol. rate constants for the reactions of xanthenium cation and 9-phenylxanthenium cations with amylamine, a neutral nucleophile. The activation energies of the two reactions were 21.6 ± 1.2 kJ mol^-1 and 18.2 ± 3.9 kJ mol^-1, resp. More importantly, we found that the rate equations determined at high temperatures extrapolated extremely well to ambient conditions. Thus, we conclude that for ion/neutral isoCoulombic reactions, it would be reasonable to use low-temperature Arrhenius parameters to predict the rate constants in water at higher temperatures Finally, we found that the effect of pressure on the bimol. rate constants at 22-330° was negligible.

Journal of Physical Chemistry A published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Product Details of C19H14O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Chen published the artcileManipulating the Assembly of Au Nanoclusters for Luminescence Enhancement and Circularly Polarized Luminescence, Safety of 2-Hydroxy-2-phenylacetic acid, the publication is Nanomaterials (2022), 12(9), 1453, database is CAplus and MEDLINE.

Au nanocluster (AuNCs)-based luminescent functional materials have attracted the interest of researchers owing to their small size, tractable surface modification, phosphorescence lifetime and biocompatibility. However, the poor luminescence quantum yield (QY) of AuNCs limits their practical applications. Herein, we synthesized a type of AuNCs modified by 4,6-diamino-2-mercaptopyrimidine hydrate (DPT-AuNCs). Furthermore, organic acids, i.e., citric acid (CA) and tartaric acid (TA), were chosen for co-assembly with DPT-AuNCs to produce AuNCs-based luminescent materials with enhanced emission. Firstly, it was found that CA could significantly enhance the emission of DPT-AuNCs with the formation of red emission nanofibers (QY = 17.31%), which showed a potential for usage in I- detection. The n···π/π···π interaction between the CA and the DPT ligand was proposed as crucial for the emission. Moreover, chiral TA could not only improve the emission of DPT-AuNCs, but could also transfer its chirality to DPT-AuNCs and induce the formation of circularly polarized luminescence (CPL)-active nanofibers. It was demonstrated that the CPL signal could increase 4.6-fold in a ternary CA/TA/DPT-AuNCs co-assembly system. This work provides a convenient way to build AuNCs-based luminescent materials as probes, and opens a new avenue for building CPL-active materials by achiral NCs through a co-assembly strategy.

Nanomaterials published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Safety of 2-Hydroxy-2-phenylacetic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xu, Baoguo published the artcileSelection of drying techniques for Pingyin rose on the basis of physicochemical properties and volatile compounds retention, COA of Formula: C10H18O, the publication is Food Chemistry (2022), 132539, database is CAplus and MEDLINE.

Awareness of edible rose being beneficial for health has attracted researchers in exploring different rose products. The study aimed to investigate effects of vacuum freeze drying (VFD), hot air drying (HAD), heat pump drying (HPD), relative humidity drying (RHD) and catalytic IR drying (CID) on the physicochem. properties, and volatile organic compounds (VOCs) of Pingyin roses. Results showed that the VFD roses had significantly (p < 0.05) bright color, complete tissue cells, low shrinkage, and good plasma membrane permeability. CID roses showed the highest total phenols content (164.09 ± 0.88 mg/g) and the strongest antioxidant activity. Besides, the odor is the most crucial indicator for dried roses. VFD can well prevent the odor from diminishing/destroying and preserve the natural smell of rose. Thermal drying including HAD, HPD, RHD, and CID, could cause significant losses of VOCs. Consequently, the findings can provide the scientific basis for future large-scale production of dried rose products.

Food Chemistry published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C12H10FeO4, COA of Formula: C10H18O.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Qiuxu published the artcileSimultaneous determination of seven bisphenol analogues in surface water by solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry, Quality Control of 80-09-1, the publication is Microchemical Journal (2022), 107098, database is CAplus.

For the simultaneous determination of seven types of bisphenol analogs (BPs) in surface water, a method combining solid-phase extraction (SPE) with ultra-performance liquid chromatog.-tandem mass spectrometry (UPLC-MS/MS) was developed. The extraction efficiency was improved by optimizing the parameters that affect it, including the sorbent types of SPE cartridge, pH, enrichment factor, flow rate, rinsing and elution volume On the basis of the single factor experiments, an attempt to obtain the result of optimizing by response surface methodol. was made, and the optimal parameters were as follows: at a flow rate of 8 mL/min, 1000 mL of water sample was run through the hydrophilic-lipophilic balance cartridge, rinsed with 10% methanol, eluted with 9 mL methanol, and concentrated with nitrogen using an automatic SPE system. The analytes were separated on an Acquity UPLC BEH C18 column using gradient elution with a mobile phase of acetonitrile and 0.05% (volume/volume) ammonia, and then analyzed using UPLC-MS/MS with multiple reaction monitoring in the neg.-ion mode, with an 8-min chromatog. run time. In the range of 1.0-500μg/L, seven BPs showed good linearity with the correlation coefficient greater than 0.998. The recovery ranged from 82.3 to 96.7%, and the range of matrix effect was 89.2 to 107%. These results indicated excellent recovery and minimal matrix effect. The limits of detection were 0.05-1.5 ng/L, the relative standard deviation ranged from 2.9 to 8.5%. Applying the developed method, seven BPs in Luoma Lake and its inflow rivers were analyzed. Only five BPs were detected in Luoma Lake and four BPs were detected in inflow rivers, and the concentrations of the detected BPs were determined BPA and BPF were the predominant BPs, and the concentration of BPA was the highest.

Microchemical Journal published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C8H6ClF3, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Shihuan published the artcileHollow fiber membrane-protected amino/hydroxyl bifunctional microporous organic network fiber for solid-phase microextraction of bisphenols A, F, S, and triclosan in breast milk and infant formula, Safety of 4,4′-Sulfonyldiphenol, the publication is Food Chemistry (2022), 133217, database is CAplus and MEDLINE.

Bisphenols and triclosan have been used in various products, and exposure to these chems. may affect human health. The present study proposes a sensitive method for the determination of bisphenols A, F, S, and triclosan. The fiber was coated by amino/hydroxyl bifunctional microporous organic network and protected by polyvinylidene fluoride hollow fiber membrane for direct immersion solid phase microextraction The limit of detection was 0.005μg/L (μg/kg), and the recoveries were in the range of 76.7% to 107.5% (87.4% to 107.6%) for breast milk (infant formula), with intra-day and inter-day precisions <10.5% (7.3%) and 13.6% (8.4%), resp. Fiber-to-fiber reproducibility of < 9.5% and a lifespan of >100 cycles were obtained. The 95th percentile estimated daily intake of total bisphenols was close to temporary tolerable daily intake for infants fed by human milk, which highlighted the needs for further attention on human exposure to BPA and its substitutes.

Food Chemistry published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Safety of 4,4′-Sulfonyldiphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhuang, Haining published the artcileIsolation, identification, and application of yeast strains from the local ecosystem of Summer Black vineyard, Recommanded Product: cis-3,7-Dimethyl-2,6-Octadien-1-Ol, the publication is Journal of Food Processing and Preservation (2022), 46(3), e16341, database is CAplus.

Several indigenous yeast strains originating from the local ecosystems of Summer Black vineyard in Jingjiang, Jiangsu, China, were isolated and identified using Wallenstein Laboratory (WL) medium combined with 26S rDNA D1/D2 region sequence anal. The 18 isolated colonies were classified into four different culture types. Two yeast strains were selected for vinification of Summer Black wines, and the volatile compounds were analyzed by headspace solid-phase microextraction-gas chromatog.-mass spectrometry (HS-SPME/GC-MS). 2,3-butanediol, Et octanoate, Et hexanoate, and Et decanoate were the key odor-active compounds The wines vinificated using the two selected yeast strains had higher quantities of identified compounds than that vinificated by com. yeast. The two yeast strains isolated from the local ecosystem of Summer Black vineyard were more effective in producing aroma in Summer Black wines than com. yeast was. This study will give some guidance or fundamental data toward wine making and yeast selection and fermentation Novelty impact statement : Saccharomyces cerevisiae and Brettanomyces bruxellensis were two main strains isolated from local “Summer Black” grape yard located in Jingjiang, Jiangsu Province, China. 2,3-butanediol, Et octanoate, Et hexanoate, and Et decanoate were major contributors to the flavor of the grape wine. The two yeast strains were much more effective in producing aroma in wine than com. yeast strain BV818.

Journal of Food Processing and Preservation published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C18H26ClN3O, Recommanded Product: cis-3,7-Dimethyl-2,6-Octadien-1-Ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts