Category: alcohols-buliding-blocks

Mou, Lin-Yun published the artcilePhytochemical and chemotaxonomic investigation from the roots of Anemone vitifolia Buch.-Ham. (Ranunculaceae), HPLC of Formula: 20880-92-6, the publication is Biochemical Systematics and Ecology (2021), 104306, database is CAplus.

Phytochem. investigation from the roots of Anemone vitifolia Buch.-Ham. led to the isolation of eight compounds, including one triterpenoid saponin, two sugars, one coumarin, one amide, one saturated alkane, one olefin and one fatty acid. The structures of these metabolites were elucidated by spectroscopic data and comparisons with the data available in the literature. Among them, compound 7 ((6Z,9Z,12Z)-6,9,12-Eicosatriene) was isolated for the first time as a natural product. Furthermore, compounds 2 (D-(+)-raffinose), 3 (mixture of β-D-fructopyranose and β-D-fructofuranose) and 5 (bonaroside) were obtained from the Ranunculaceae family for the first time. Compounds 4 (siderin) and 6 (n-hexadecane) were isolated from A. vitifolia for the first time. The chemotaxonomic significance of the isolated compounds was discussed.

Biochemical Systematics and Ecology published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, HPLC of Formula: 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Alliot, Julien published the artcileA straightforward enantioselective synthesis of F17807, Quality Control of 57044-25-4, the publication is Tetrahedron (2015), 71(50), 9383-9387, database is CAplus.

An efficient approach for the enantioselective synthesis of the 1,4-benzodioxane F17807 drug is reported. The developed route relied on two key steps, namely S_NAr and Mitsunobu reactions, which permitted a straightforward access to the title compound with full preservation of the enantiomeric excess throughout the synthetic sequence.

Tetrahedron published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Quality Control of 57044-25-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Donck, Simon published the artcileMild and selective catalytic oxidation of organic substrates by a carbon nanotube-rhodium nanohybrid, Category: alcohols-buliding-blocks, the publication is Catalysis Science & Technology (2015), 5(9), 4542-4546, database is CAplus.

Rhodium nanoparticles were assembled on carbon nanotubes and the resulting nanohybrid was used for the catalytic aerobic oxidation of diverse substrates such as hydroquinones, hydroxylamines, silanes, hydrazines and thiols at room temperature The catalytic system was proved to be very efficient on the investigated substrates and demonstrated high selectivity. Furthermore, the catalyst operates under mild reaction conditions, with excellent yields and could be easily recycled without loss of activity.

Catalysis Science & Technology published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Farah, Joseph published the artcileDirect integration of gold-carbon nanotube hybrids in continuous-flow microfluidic chips: A versatile approach for nanocatalysis, Category: alcohols-buliding-blocks, the publication is Journal of Colloid and Interface Science (2022), 359-367, database is CAplus and MEDLINE.

A carbon nanotube-based packed-bed microreactor was developed for the on-chip oxidation of silanes. The process is catalyzed by a heterogeneous gold-carbon nanotube hybrid that was embedded in the device using a micrometric restriction zone. Integration of the nanohybrid permitted efficient flow aerobic oxidation of the substrates into the corresponding silanols with high selectivity and under sustainable conditions.

Journal of Colloid and Interface Science published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

John, Jubi published the artcileCatalytic Oxidation of Silanes by Carbon Nanotube-Gold Nanohybrids, Computed Properties of 17877-23-5, the publication is Angewandte Chemie, International Edition (2011), 50(33), 7533-7536, S7533/1-S7533/37, database is CAplus and MEDLINE.

Here reported an alternative strategy which has led to the discovery of the most efficient catalytic system to date for silane oxidation The approach involves layer-by-layer (LBL) assembly of gold nanoparticles on carbon nanotubes (CNT₅). Nanotubes provide high sp. surface area and excellent nanoparticle (NP) dispersion. In addition, nanotubes are electronically active and stabilization of transient higher oxidation states of gold are anticipated by collaborative interactions with the metal. To the best of authors knowledge, this is the first report on silane oxidation by CNT-supported catalysts. Thus, gold carbon nanotube catalyzed oxidation of PhSiMe₂H in THF/H₂O in the presence of air gave 98% PhSiMe₂OH in 45m at room temperature

Angewandte Chemie, International Edition published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Computed Properties of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Villemin, Elise published the artcilePolydiacetylene Nanotubes in Heterogeneous Catalysis: Application to the Gold-Mediated Oxidation of Silanes, Synthetic Route of 17877-23-5, the publication is Macromolecular Chemistry and Physics (2015), 216(24), 2398-2403, database is CAplus.

A layer-by-layer approach is used to anchor small gold nanoparticles onto organic nanotubes resulting from the self-assembly and polymerization of diacetylene-containing nitrilotriacetic amphiphiles. The obtained nanotube-gold hybrid is used as a catalyst for the aerobic oxidation of various silanes. With minimal gold loading (0.05 mol%), all substrates are converted into the corresponding silanols with hydrogen gas as the only byproduct. The catalyst operates under mild conditions and can be easily recycled, losing neither activity nor selectivity.

Macromolecular Chemistry and Physics published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C6H8O3, Synthetic Route of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Langford, Vaughan S. published the artcileSelected ion flow tube studies of several siloxanes, HPLC of Formula: 597-52-4, the publication is Rapid Communications in Mass Spectrometry (2013), 27(6), 700-706, database is CAplus and MEDLINE.

People are using increasing amounts of siloxanes which ultimately end up in landfills, then in landfill gas and biogas digesters. Their presence poses difficulties for industries to use the energy content of landfill gas and biogas because the combustion process oxidizes Si to SiO₂ which in turn damages engine parts. Rapid, efficient, accurate methods are needed to quantify the presence of siloxanes. Selected ion flow tube mass spectrometry (SIFTMS), an emerging real-time technique, is used to monitor trace volatile compounds in air. Samples containing the trace volatile compounds are drawn into the flow tube and convected in a He stream. Chem. ionization reactions from mass-selected reagent ions with the volatile compounds occur. To quantify volatile compounds in the sample, the ion chem. of the reagent ion with each volatile must be known. Rate coefficients and product ion branching ratios were determined for dodecamethylpentasiloxane, decamethylcyclopentasiloxane, decamethyltetrasiloxane, octamethylcyclotetrasiloxane, triethylsilanol, tetramethylsilane, and hexamethyldisilazane. The ion/mol. reactions of these 7 Si-containing compounds were fast, occurring at or near the collision rate, allowing for low concentration detection. The very simple reaction chem. of proton transfer, electron transfer, and Me loss enables easy siloxane quantitation in landfill gas and biogas by SIFTMS. Copyright © 2013 John Wiley & Sons, Ltd.

Rapid Communications in Mass Spectrometry published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, HPLC of Formula: 597-52-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Askey, Hannah E. published the artcilePhotocatalytic Hydroaminoalkylation of Styrenes with Unprotected Primary Alkylamines, Quality Control of 6346-09-4, the publication is Journal of the American Chemical Society (2021), 143(39), 15936-15945, database is CAplus and MEDLINE.

A solution to these problems using organophotoredox catalysis, enabling a direct, modular and sustainable preparation of α-(di)substituted γ-arylamines, including challenging electron-neutral and moderately electron-rich aryl groups was reported. A broad range of functionalities were tolerated, and the reactions was run on multigram scale in continuous flow. The method was applied to a concise, protecting-group-free synthesis of the blockbuster drug Fingolimod, as well as a phosphonate mimic of its in-vivo active form (by iterative α-C-H functionalization of ethanolamine). The reaction was sequenced with an intramol. N-arylation to provided a general and modular access to valuable (spirocyclic) 1,2,3,4-tetrahydroquinolines and 1,2,3,4-tetrahydronaphthyridines. Mechanistic and kinetic studies supportes an irreversible hydrogen atom transfer activation of the alkylamine by the azidyl radical and some contribution from a radical chain. The reaction was photon-limited and exhibits a zero-order dependence on amine, azide, and photocatalyst, with a first-order dependence on styrene.

Journal of the American Chemical Society published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H19NO2, Quality Control of 6346-09-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ghislieri, Diego published the artcileEngineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products, COA of Formula: C8H19NO2, the publication is Journal of the American Chemical Society (2013), 135(29), 10863-10869, database is CAplus and MEDLINE.

The development of cost-effective and sustainable catalytic methods for the production of enantiomerically pure chiral amines is a key challenge facing the pharmaceutical and fine chem. industries. This challenge is highlighted by the estimate that 40-45% of drug candidates contain a chiral amine, fueling a demand for broadly applicable synthetic methods that deliver target structures in high yield and enantiomeric excess. Herein we describe the development and application of a “toolbox” of monoamine oxidase variants from Aspergillus niger (MAO-N) which display remarkable substrate scope and tolerance for sterically demanding motifs, including a new variant, which exhibits high activity and enantioselectivity toward substrates containing the aminodiphenylmethane (benzhydrylamine) template. By combining rational structure-guided engineering with high-throughput screening, it has been possible to expand the substrate scope of MAO-N to accommodate amine substrates containing bulky aryl substituents. These engineered MAO-N biocatalysts have been applied in deracemization reactions for the efficient asym. synthesis of the generic active pharmaceutical ingredients Solifenacin and Levocetirizine as well as the natural products (R)-coniine, (R)-eleagnine, and (R)-leptaflorine. We also report a novel MAO-N mediated asym. oxidative Pictet-Spengler approach to the synthesis of (R)-harmicine.

Journal of the American Chemical Society published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H19NO2, COA of Formula: C8H19NO2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Matviitsuk, Anastassia published the artcileUnanticipated Silyl Transfer in Enantioselective α,β-Unsaturated Acyl Ammonium Catalysis Using Silyl Nitronates, Application of Triisopropylsilanol, the publication is Organic Letters (2020), 22(1), 335-339, database is CAplus and MEDLINE.

The use of silyl nitronates is reported for the isothiourea-catalyzed synthesis of γ-nitro-substituted silyl esters containing up to two contiguous stereocenters in good yields with excellent enantioselectivities (up to 93% yield and 99:1 er). The serendipitously discovered formation of silyl ester products in this reaction demonstrates a novel platform for catalyst turnover in α,β-unsaturated acyl ammonium catalysis.

Organic Letters published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Application of Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts