Category: alcohols-buliding-blocks

Li, Yingwei published the artcileHydrogen Evolution Electrocatalyst Design: Turning Inert Gold into Active Catalyst by Atomically Precise Nanochemistry, Name: 2-Phenylethanethiol, the publication is Journal of the American Chemical Society (2021), 143(29), 11102-11108, database is CAplus and MEDLINE.

Electrocatalytic hydrogen evolution reaction (HER) holds promise in the renewable clean energy scheme. Crystalline Au and Ag are, however, poor in catalyzing HER, and the ligands on colloidal nanoparticles are generally another disadvantage. Herein, we report a thiolate (SR)-protected Au₃₆Ag₂(SR)₁₈ nanocluster with low coverage of ligands and a core composed of three icosahedral (I_h) units for catalyzing HER efficiently. This trimeric structure, together with the monomeric I_h Au₂₅(SR)₁₈^– and dimeric I_h Au₃₈(SR)₂₄, constitutes a unique series, providing an opportunity for revealing the correlation between the catalytic properties and the catalyst′s structure. The Au₃₆Ag₂(SR)₁₈ surprisingly exhibits high catalytic activity at lower overpotentials for HER due to its low ligand-to-metal ratio, low-coordinated Au atoms and unfilled superat. orbitals. The c.d. of Au₃₆Ag₂(SR)₁₈ at -0.3 V vs RHE is 3.8 and 5.1 times that of Au₂₅(SR)₁₈^– and Au₃₈(SR)₂₄, resp. D. functional theory (DFT) calculations reveal lower hydrogen binding energy and higher electron affinity of Au₃₆Ag₂(SR)₁₈ for an energetically feasible HER pathway. Our findings provide a new strategy for constructing highly active catalysts from inert metals by pursuing atomically precise nanoclusters and controlling their geometrical and electronic structures.

Journal of the American Chemical Society published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Name: 2-Phenylethanethiol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sun, Jie published the artcileA dual probe for selective sensing of Zn (II) by fluorescent and Cu (II) by colorimetric methods in different systems based on 7,8-benzochromone-3-carbaldehyde -(fluorescein)hydrazone, Synthetic Route of 86-48-6, the publication is Journal of Photochemistry and Photobiology, A: Chemistry (2021), 113007, database is CAplus.

In this study, a novel fluorescent probe sensor, 7,8-benzochromone-3-carbaldehyde (fluorescein)hydrazone L, was designed and synthesized. Based on the photoinduced electron transfer (PET) process, L can detect Zn²⁺ in the solution of EtOH/H₂O (9/1, V/V). The probe had high selectivity and sensitivity to Zn²⁺ with a lower detection limit of 3.4 x 10^-7 M. Furthermore, the coordination ratio of L-Zn²⁺ was 1:1, which could be corroborated by Job′s plot. In addition, in the EtOH/ H₂O (5/2, V/V) solution of the probe L, Cu²⁺ was added to produce a marked change in color from achromatous to yellow, indicating that the probe L could detect Cu²⁺ by colorimetry, which was detectable by the naked eye, simply and quickly. According to the Benesi-Hildebrand equation, the complexing constants values of L-Zn²⁺ and L-Cu²⁺ were 9.8 x 104 M²⁺ and 1.009 x 105 M²⁺, resp.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C6H5F4NO3S, Synthetic Route of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lu, Jian-ping published the artcileClinical effect of hemabate in prevention and treatment of postpartum hemorrhage and adverse events among high risk pregnant women receiving cesarean section, Category: alcohols-buliding-blocks, the publication is Zhongguo Fuyou Baojian (2016), 31(18), 3717-3719, database is CAplus.

Objective To explore the clin. effect of hemabate in prevention and treatment of postpartum hemorrhage and adverse events among high risk pregnant women receiving cesarean section, accumulate experience for clin. optimization strategy among the population. Methods From June 2010 to Oct. 2013, 78 pregnant women underwent cesarean section in Department of Obstetrics and Gynecol. in the hospital were selected, then they were divided into study group and control group according to random number table, 39 cases in each group. The cases in control group were treated by oxytocin combined with carboprost methylate suppositories, while the cases in study group were treated by hemabate. The amounts of blood loss and urine volumes during operation and at 2 and 24 h after operation in the two groups were recorded, the incidence rates of adverse events in the two groups were compared. Results The amount of blood loss during operation and at 2 and 24 h after operation in study group were statistically significantly lower than those in control group (P<0.05). Urine volumes during operation and at 2 and 24 h after operation in study group were statistically significantly higher than those in control group (P<0.05). The incidence rate of adverse reactions in study group was statistically significantly lower than that in control group (P<0.05). Conclusion For the high-risk pregnant women receiving cesarean section, the clin. efficacy and safety of hemabate in prevention and treatment of postpartum hemorrhage are better than those of oxytocin combined with carboprost methylate suppositories, which is worthy of further promotion and application in clin. practice.

Zhongguo Fuyou Baojian published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhao, Mu published the artcileCharacterization of key aroma-active compounds in Hanyuan Zanthoxylum bungeanum by GC-O-MS and switchable GC x GC-O-MS, Formula: C10H18O, the publication is Food Chemistry (2022), 132659, database is CAplus and MEDLINE.

The present study sought to characterize the composition of volatile aroma compounds and key aroma-active compounds of dried Hanyuan Zanthoxylum bungeanum. The volatile aroma compounds were analyzed by the solid-phase microextraction (SPME) combined with gas chromatog.-olfactometry-mass spectrometry (GC-O-MS) and two-dimensional comprehensive gas chromatog.-olfactometry-mass spectrometry (GC x GC-O-MS). The key aroma-active compounds were analyzed by the aroma extract dilution anal. and odor activity value. A total of 72 volatile compounds were identified by GC-O-MS, of which 28 were aroma-active. Meanwhile, 116 volatile compounds were identified by GC x GC-O-MS, of which 43 were aroma-active. These results revealed that myrcene, (+)-limonene, (E)-β-ocimene, β-cubebene, Germacrene D, cineole, linalool, and linalyl acetate were the key aroma-active compounds of dried Hanyuan Zanthoxylum bungeanum.

Food Chemistry published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C17H29BO2, Formula: C10H18O.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tang, Ri-Yuan published the artcileConformation-induced remote meta-C-H activation of amines, Product Details of C7H9NO, the publication is Nature (London, United Kingdom) (2014), 507(7491), 215-220, database is CAplus and MEDLINE.

Achieving site selectivity in carbon-hydrogen (C-H) functionalization reactions is a long-standing challenge in organic chem. The small differences in intrinsic reactivity of C-H bonds in any given organic mol. can lead to the activation of undesired C-H bonds by a non-selective catalyst. One solution to this problem is to distinguish C-H bonds on the basis of their location in the mol. relative to a specific functional group. In this context, the activation of C-H bonds five or six bonds away from a functional group by cyclometallation has been extensively studied. However, the directed activation of C-H bonds that are distal to (more than six bonds away) functional groups has remained challenging, especially when the target C-H bond is geometrically inaccessible to directed metalation owing to the ring strain encountered in cyclometallation. Here we report a recyclable template that directs the olefination and acetoxylation of distal meta-C-H bonds – as far as 11 bonds away – of anilines and benzylic amines. This template is able to direct the meta-selective C-H functionalization of bicyclic heterocycles via a highly strained, tricyclic-cyclophane-like palladated intermediate. X-ray and NMR studies reveal that the conformational biases induced by a single fluorine substitution in the template can be enhanced by using a ligand to switch from ortho- to meta-selectivity.

Nature (London, United Kingdom) published new progress about 14703-69-6. 14703-69-6 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Phenol, name is 3-(Methylamino)phenol, and the molecular formula is C6H12Br2, Product Details of C7H9NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cheng, Yujiao published the artcileFlavor deterioration of Mandarin juice during storage by MDGC-MS/O and GC-MS/PFPD, Synthetic Route of 106-25-2, the publication is LWT–Food Science and Technology (2022), 113132, database is CAplus.

Com. mandarin juice often exhibits flavor deterioration during storage. The changes in volatile flavor profiles were investigated in mandarin juice stored under three different temperature conditions (4°C, 25°C, and 40°C). The application of multidimensional gas chromatog.-mass spectrometry/olfactometry (MDGC-MS/O) coupled with aroma extract dilution anal. (AEDA) identified 31 odorants in stored mandarin juice, including seven off-flavor contributing compounds: methanethiol (unpleasant, repulsive), di-Me sulfide (sulfur, cabbage), methional (cooked potato), p-cymene (solventy), 4-vinylguaiacol (medicine), terpinen-4-ol (wood), and α-terpineol (floral, mint). 4-Vinylguaiacol was also identified in mandarin juice for the first time. In addition, 64 volatile compounds determined by GC-MS/pulsed flame photometric detector (GC-MS/PFPD) were classified as alcs., terpenes, volatile sulfur compounds (VSCs), aldehydes, esters, ketones, and phenols. Volatile compound differences were observed in mandarin juice under different storage conditions by heat-map generation and principal component anal. (PCA). The results revealed that high-temperature storage led to a rapid increase in the concentration of total alcs. and VSCs. Furthermore, the flavor deterioration markers α-terpineol and di-Me sulfide were identified based on off-flavor contribution and variable importance in projection (VIP) (score >1) values in the PLS-DA model. These two compounds are valuable for marker-assisted flavor deterioration anal. in mandarin juice during storage.

LWT–Food Science and Technology published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Synthetic Route of 106-25-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ma, Xinxia published the artcileObservation on carboprost tromethamine and oxytocin for reduction of hemorrhage in caesarean section, Application of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, the publication is Zhonghua Fuyou Linchuang Yixue Zazhi, Dianziban (2014), 10(5), 73-76, database is CAplus.

Objective: To observe the effect of carboprost tromethamine (hemabate) and oxytocin in cesarean section for preventing and reducing the intraoperative bleeding and compare their adverse reaction. Methods: From Nov. 2013 to March 2014, a total of 40 parturient women underwent cesarean section were included in the study. They were randomly divided into group I (20 cases using carboprost tromethamine injection) and group II (20 cases using oxytocin) according to different drugs for the injection into their uterine corpus immediately after fetal disengagement. There were no significant differences in maternal age, gestational age, body weight in general between two groups (P > 0.05). The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Shanghai First Maternity and Infant Hospital. Informed consent was obtained from each participants. Results: The amount of blood loss during cesarean section in group I was obviously lower than that of group II (P < 0.05). There were significant differences in vital signs at 10 min after treatment between two groups (P < 0.05). The incidence rate of adverse reaction in group I was significantly higher than that of group II (P < 0.01). Conclusion: Carboprost tromethamine injection in caesarean operation can effectively decrease the intraoperative bleeding, but more attention should be paid on its adverse reaction.

Zhonghua Fuyou Linchuang Yixue Zazhi, Dianziban published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Application of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lin, Wenjing published the artcilePrevention effect of Guyuan Fujiu decoction combined with carboprost tromethamine on postpartum hemorrhage caused by uterine inertia in vaginal delivery, Application In Synthesis of 58551-69-2, the publication is Jianyan Yixue Yu Linchuang (2021), 18(16), 2335-2338, 2343, database is CAplus.

Objective To observe the preventive effect of Guyuan Fujiu decoction combined with carboprost tromethamine on postpartum hemorrhage caused by uterine inertia in vaginal delivery. Methods A total of 110 cases of postpartum hemorrhage due to uterine inertia in the hospital from Apr. 2018 to June 2020 were randomly divided into control group and observation group, 55 cases in each group. The control group was given carboprost tromethamine injection after the delivery of the fetus, and the observation group was given Guyuan Fujiu decoction on the basis of the control group. The incidence of postpartum hemorrhage, amount of postpartum hemorrhage, hemostatic time, use of other hemostatic measures, changes of Hb and hematocrit were compared between the two groups. Results The postpartum hemorrhage rate of the observation group (3.64%) was significantly lower than that of the control group (14.55%), the difference was statistically significant (χ²=3.960, P<0.05). Postpartum hemostasis time [(23.56±3.14) min] was significantly shorter than that in the control group [(40.05±5.74) min], the difference was statistically significant (t=18.691, P<0.05). Compared with the control group, the amount of bleeding in the observation group decreased significantly at 30 min, 2 h and 24 h postpartum (t=8.654, 13.495 and 15.496, P<0.05). The application rate of other hemostatic measures in the observation group (7.27%) was significantly lower than that in the control group (21.82%) (χ²=4.681, P<0.05). Compared with the control group, the decrease of maternal Hb and hematocrit in the observation group were significantly reduced (t=22.817, 28.939, P<0.05). Compared with the control group, the serum D-dimer level in the observation group was significantly lower at 2 h postpartum, and the FIB level was significantly higher (t=19.492, 17.256, P<0.05). The level of serum antithrombin-III in the observation group was significantly higher than that in the control group (t=6.090, 10.092, P<0.05). The adverse reaction rate of the observation group (7.27%) was lower than that of the control group (16.36%), but the difference was not statistically significant (χ²=2.181, P>0.05). Conclusion Guyuan Fuguo decoction combined with carboprost tromethamine can be used to prevent uterine hypostasis postpartum hemorrhage, reduce postpartum hemorrhage, improve coagulation function, promote uterine contraction and drug safety.

Jianyan Yixue Yu Linchuang published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Application In Synthesis of 58551-69-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yuan, Shiyu published the artcileMeasurement of non-hindered and hindered phenolic species in aviation fuels via tandem-SPE with comprehensive GC x GC-MS/FID, Application of 4-Propylphenol, the publication is Fuel (2021), 119561, database is CAplus.

Phenolic species have a great impact on the thermal oxidation stability of aviation fuels. However, it is difficult to measure phenolic complex composition and trace content. In this paper, a novel method based on tandem-solid phase extraction (SPE) with comprehensive two-dimensional gas chromatog. (GC x GC)-mass spectrometry (MS) and flame ionization detector (FID) was proposed for measurement of phenolic species in aviation fuels. The tandem of normal phase SPE and anion exchange SPE was employed to extract non-hindered and hindered phenolic species resp. from aviation fuels, and comprehensive GC x GC-MS/FID was used to identify and quantify individual phenolic species with few co-elution. Ninety-eight kinds of phenolic species were identified manually in aviation fuels according to the characteristic m/z and phenolic distribution regular in the 2D chromatogram. Quant. accuracy for phenolic species was verified as their recoveries were satisfactory, especially hindered phenols (BHT), which were totally deprotonated by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD). Each phenolic species was individually quantified using calibration curve library. Moreover, this work analyzed the adsorption characteristics of phenolic isomers in tandem-SPE procedure and the variation of the contents of phenolic and other oxygenated species after thermal stress. This is an accurate and complete method for measurement of non-hindered and hindered phenolic species in aviation fuels, which is of great significance to establish and improve the kinetic model of thermal oxidation deposition.

Fuel published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C13H14N2O, Application of 4-Propylphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Huifang published the artcilePhotocatalytic Cleavage of C-C Bond in Lignin Models under Visible Light on Mesoporous Graphitic Carbon Nitride through π-π Stacking Interaction, Related Products of alcohols-buliding-blocks, the publication is ACS Catalysis (2018), 8(6), 4761-4771, database is CAplus.

Photocatalysis is a potentially promising approach to harvest aromatic compounds from lignin. However, the development of an active and selective solid photocatalyst is still challenging for lignin transformation under ambient conditions. We herein report a mild photocatalytic oxidative strategy for C-C bond cleavage of lignin β-O-4 and β-1 linkages using a mesoporous graphitic carbon nitride catalyst. Identifications by solid-state NMR techniques and d. functional theory (DFT) calculations indicate that π-π stacking interactions are most likely present between the flexible carbon nitride surface and lignin model mol. Besides, low charge recombination efficiency and high sp. surface area (206.5 m² g^-1) of the catalyst also contribute to its high catalytic activity. Mechanistic investigations reveal that photogenerated holes, as the main active species, trigger the oxidation and C-C bond cleavage of lignin models. This study sheds light on the interaction between complex lignin structures and the catalyst surface and provides a new strategy of photocatalytic cleavage of lignin models with heterogeneous photocatalysts.

ACS Catalysis published new progress about 70110-65-5. 70110-65-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Alcohol,Ether,Benzene Compounds, name is 2-Phenoxy-1-phenylpropane-1,3-diol, and the molecular formula is C15H16O3, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts