Category: alcohols-buliding-blocks

Veeraperumal, Suresh published the artcilePolysaccharides from Gracilaria lemaneiformis promote the HaCaT keratinocytes wound healing by polarised and directional cell migration, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is polysaccharide Gracilaria lemaneiformis wound healing promoter cell proliferation; Cell migration; Cell polarisation; Gracilaria lemaneiformis; Human keratinocyte; Wound healing.

In this study, we evaluated the wound healing activity of polysaccharides fractions from Gracilaria lemaneiformis. Three purified fractions, namely, GLP-1, GLP-2 and GLP-3 were obtained from anion-exchange chromatog. and were evaluated for their cell proliferation activity. Among the three fractions, the fraction GLP-2 promoted cell proliferation at a concentration of 100μg/mL. Further, chem. and structural anal. of GLP-2 revealed it to be a homogenous and repeating structure of alternating 4-linked 3,6-anhydro-α-L-galactopyranosyl and 3-linked β-D-galactopyranosyl units with sulfate residues. Further, we analyzed the wound healing activities of the fraction GLP-2 and its underlying mechanisms. The results showed that GLP-2 promotes cell proliferation and migration through activation of PI3 K/aPKC signaling during human keratinocytes wound healing. Based on the findings in this study, we concluded that the wound healing activities of the GLP-2 fraction can provide the scientific basis for the development of G. lemaneiformis polysaccharides based product for wound management.

Carbohydrate Polymers published new progress about Cell migration. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Prestes, Alessandro de Souza published the artcileMethylglyoxal disrupts the functionality of rat liver mitochondria, SDS of cas: 97-67-6, the main research area is liver mitochondria superoxide phosphorylation bioenergetics methylglyoxal; High-resolution respirometry; Methylglyoxal; Mitochondria; Oxidative stress.

Methylglyoxal (MG) is a reactive metabolite derived from different physiol. pathways. Its production can be harmful to cells via glycation reactions of lipids, DNA, and proteins. But, the effects of MG on mitochondrial functioning and bioenergetic responses are still elusive. Then, the effects of MG on key parameters of mitochondrial functionality were examined here. Isolated rat liver mitochondria were exposed to 0.1-10 mM of MG to determine its toxicity in the mitochondrial viability, membrane potential (Δψm), swelling and the superoxide (O·-2) production Besides, mitochondrial oxidative phosphorylation parameters were analyzed by high-resolution respiratory (HRR) assay. In this set of experiments, routine state, PM state (pyruvate/malate), oxidative phosphorylation (OXPHOS), LEAK respiration, electron transport system (ETS) and oxygen residual (ROX) states were evaluated. HRR showed that PM state, OXPHOS CI-Linked, LEAK respiration, ETS CI/CII-Linked and ETS CII-Linked/ROX were significantly inhibited by MG exposure. MG also inhibited the complex II activity, and decreased Δψm and the viability of mitochondria. Taken together, our data indicates that MG is an inductor of mitochondrial dysfunctions and impairs important steps of respiratory chain, effects that can alter bioenergetics responses.

Chemico-Biological Interactions published new progress about Cell viability. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, SDS of cas: 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Kai published the artcileFruity aroma modifications in Merlot wines during simultaneous alcoholic and malolactic fermentations through mixed culture of S. cerevisiae, P. fermentans, and L. brevis, Safety of 3-(Methylthio)propan-1-ol, the main research area is alc malolactic fermentation Lactobacillus brevis Saccharomyces cerevisiae Pichia fermentans.

As a group of wine lactic acid bacteria, Lactobacillus has gained growing interest in malolactic fermentation due to possessing diverse aroma-related enzymes. In this study, a Lactobacillus brevis 26 with high β-glucosidase activity was isolated, and co-inoculated with yeasts (Saccharomyces cerevisiae and Pichia fermentans) to characterize fruity aroma modifications in Merlot wine. Compared with the traditional inoculation (sequential inoculation of L. brevis 26 after alc. fermentation by yeasts), co-inoculation of the three species induced simultaneous alc. and malolactic fermentations, leading to a pronounced reduction in total fermentation duration. P. fermentans increased L. brevis 26 cell viability when co-fermented with the predominant species S. cerevisiae. Meanwhile, the β-glucosidase activity of L. brevis 26 elevated terpene contents, and P. fermentans induced the production of higher alc. acetates and fatty acid Et esters. Sensory anal. showed that co-inoculation-based wines had enhanced complexity of fruity aroma profiles associated with jammy and temperate fruity notes.

LWT–Food Science and Technology published new progress about Cell viability. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Safety of 3-(Methylthio)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pinheiro, Fernanda C. published the artcileDispersive liquid-liquid microextraction of Cd, Hg and Pb from medicines prior to ICP OES determination according to the United States Pharmacopeia, Application In Synthesis of 111-87-5, the main research area is cadmium mercury lead tablet dispersive liquid microextraction ICPOES.

A simple, sensitive and matrix-effect free anal. method for simultaneous determination of Cd, Hg and Pb in drug samples (i.e., com. dosage tablets) by inductively coupled plasma optical emission spectrometry (ICP OES) has been developed. According to the USP (USP) Chapter 232, those metals are considered elemental impurities from class 1 and they must be assessed in pharmaceutical production as well as in quality control evaluation. In order to increase the sensitivity of the anal., dispersive liquid-liquid microextraction (DLLME) was performed and seven factors affecting analyte extraction were optimized by multivariate anal. A microvolume of analyte enriched phase was directly introduced into the plasma using a multi-nebulizer, providing a high enrichment factor. When compared to conventional ICP OES anal., DLLME improves the limit of quantitation (LOQ) values on average 40-fold for all analytes. Consequently, LOQ values were significantly lower than their permissible daily exposure limits for oral drugs. Accuracy was evaluated by addition and recovery experiments following USP recommendations in eight com. drug samples. Recovery and RSD values were within the range of 90-108% and 1-9%, resp.

Analytical Methods published new progress about Centrifugation. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gomez-Ramos, M. M. published the artcileExploration of environmental contaminants in honeybees using GC-TOF-MS and GC-Orbitrap-MS, Application In Synthesis of 124-76-5, the main research area is environmental contaminant honeybee Apis GC TOF MS Orbitrap; pollutant PAH phthalate synthetic musk Apis; Environmental contaminants; GC-EI-TOF-MS; GC-Orbitrap-MS; Honeybee; Non-targeted screening.

This study reports an anal. approach by gas chromatog. and high-resolution mass spectrometry (HRMS) intended to be used for investigation of nontargeted environmental contaminants in honeybees. The approach involves a generic extraction and anal. with two GC-HRMS systems: time-of-flight and Orbitrap analyzers, GC-TOF-MS, and GC-Orbitrap-MS operated in electron-impact ionization (EI) mode. The workflow for screening of non-targeted contaminants consisted of initial peak detection by deconvolution and matching the first-stage mass spectra EI-MS with a nominal mass spectral library. To gain further confidence in the structural characterization of the contaminants under investigation, mol. formula of representative ions (mol. and fragment ions) was provided for those with an accurate mass scoring (error < 5 ppm). This methol. was applied for screening environmental contaminants in 75 samples of adult honeybee. This approach has provided the tentative identification of environmental contaminants belonging to different chem. groups, among them, PAHs, phthalates and synthetic musks. Residues of veterinary treatments used in apiculture were also detected in the honeybee samples. Science of the Total Environment published new progress about Apis mellifera. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application In Synthesis of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

da Silva, Priscila Missio published the artcileStability of volatile compounds of honey during prolonged storage, HPLC of Formula: 584-02-1, the main research area is volatile compound stability honey prolonged storage; Aroma compounds; Degradation; Honey; Storage; Volatile compounds.

The aim of the study was to identify, via headspace solid phase microextraction and gas chromatog.-mass spectrometry, volatile compounds in eight no processing Apis mellifera L. honey samples produced in the state of Santa Catarina, Brazil, and monitor their stability over 540 days of storage at 20 ± 4°C, searching for possible degradation indicators compounds The result of the initial anal. showed the presence of 32 volatile compounds and 24 were selected for the evaluation of the behavior over the storage. The volatiles cis- and trans-linalool oxide and hotrienol showed increased over 540 days, except for one sample, which showed a decrease in the cis- and trans- linalool oxide contents. Other compounds (Et acetate, 1-hexanol. 2-Et, benzoic acid. Et ester, butanoic acid. 3-Me, butanoic acid. 2-Me, and salicylic acid. tert.-Bu ester) were detected in at least one sample from 360 days of storage. Considering the storage system applied, the compounds cis- and trans-linalool oxide and hotrienol, which were found in all samples and times evaluated, can be considered possible indicators compounds of degradation of honey.

Journal of Food Science and Technology (New Delhi, India) published new progress about Apis mellifera. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, HPLC of Formula: 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Caputo, Lucia published the artcileChemical composition and biological activities of essential oils from peels of three Citrus species, Name: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Citrus fruit peelessential oil chem composition phototoxicity biol activity; Citrus limon; Citrus × bergamia; Citrus × myrtifolia; eco-compatibility; essential oil; phytotoxicity.

Fruit peels are generally underutilized byproducts of the food industry, although they are valuable sources of bioactive compounds The aim of this study is to evaluate a new application for three Citrus peel EOs as bio-herbicides. After a micro-morphol. evaluation of Citrus peels by SEM anal., the phytochem. composition of the EOs of Citrus x bergamia Risso & Poit., Citrus x myrtifolia Raf., and Citruslimon (L.) Osbeck was characterized by GC/FID and GC/MS analyses. The in vitro phytotoxicity against germination and initial radical elongation of several crop and weed species was evaluated. Furthermore, the eco-compatibility of these EOs has been assessed by the brine shrimp (Artemia salina) lethality assay. SEM anal. highlighted the morphometric differences of the schizolysigenous pockets among the peels of the three Citrus species. Oxygenated monoterpenes are the main constituents in C. x bergamia (51.09%), whereas monoterpene hydrocarbons represent the most abundant compounds in C. x myrtifolia (82.15%) and C. limon (80.33%) EOs. They showed marked and selective phytotoxic activity in vitro, often at very low concentration (0.1 μg/mL) against all plant species investigated, without showing any toxicity on Artemia salina, opening the perspective of their use as safe bio-herbicides.

Molecules published new progress about Artemia salina. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Name: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hao, Xiaojing published the artcileA gel polymer electrolyte based on PVDF-HFP modified double polymer matrices via ultraviolet polymerization for lithium-sulfur batteries, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate), the main research area is PVDF HFP UV polymerization lithium sulfur battery; Gel polymer electrolyte; Lithium-sulfur battery; Quasi-solid-state; Ultraviolet polymerization.

Currently, as a new kind of separator, gel polymer electrolytes (GPEs) not only should play a role to sep. cathode and anode, but also should have high ionic conductivity to guarantee the elevated electrochem. performances. As for quasi-solid-state lithium-sulfur batteries (LSBs), it is also very important to confine the shuttle effect and Li dendrite growth. Herein, we synthesize GPEs polymerized under UV, in which the poly(vinylidene fluoride-hexafluoro propylene) (PVDF-HFP) is one of the polymer matrixes to provide high ionic conductivity and toughness, pentaerythritol tetrakis-divinyl adipate (PETT-DA) is another polymer matrix to simultaneously suppress shuttle effect and lithium dendrite. More importantly, Li6.4La3Zr1.4Ta0.6O12 (LLZTO) provides the Li+ transport sites to facilitate the Li+ transport speed. Meanwhile, it can hinder the crystallization of polymers, reducing crystallinity of GPEs. Prominently, the designed GPEs with 10 wt% LLZTO have elevated ionic conductivity of 8.74 × 10-4 S cm-1 and Li+ transference number of 0.69, accompanied with superb capacity retention of 88.6% after 300 cycles at 1C. Importantly, the excellent mech. properties and thermal stability give more potentials to the commercialization of LSBs.

Journal of Colloid and Interface Science published new progress about Battery anodes. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Xiuli published the artcile3D ultraviolet polymerized electrolyte based on PEO modified PVDF-HFP electrospun membrane for high-performance lithium-sulfur batteries, Name: Pentaerythritol tetra(3-mercaptopropionate), the main research area is lithium sulfur battery gel polymer electrolyte nanofiber UV polymerization.

At present, the quasi-solid-state lithium-sulfur batteries (LSBs) assembled with sulfur cathode, gel polymer electrolyte (GPE) and Li anode have explored a novel prospect for substantial energy applications owing to the high energy d. and elevated security. In this work, we propose a 3D UV polymerized electrolyte, in which the inner substrate is the PEO modified PVDF-HFP electrospun membrane, and the hydrogen bonding effect plays a critical role in regulating the nanofiber diameter and membrane porosity. Simultaneously, outside coating is the in-situ UV polymerized pentaerythritol tetrakis-divinyl adipate (PETT-DA) layer, in which the carbonyl groups can effectively suppress the polysulfides shuttling. Consequently, the optimal electrolyte membranes with high porosity possess the high electrolyte uptake of 279.8%, ionic conductivity of 9.64 × 10-4 S cm-1 and Li+ transference number of 0.71 at 25 °C. Prominently, the assembled quasi-solid-state LSBs exhibit the stable coulombic efficiency of 99.5-100.0% over 300 cycles and good capacity retention of 87.1% after 300 cycles at 2C. More importantly, excellent thermal dimensional properties and mech. performances further provide great com. potentials for our synthesized 3D electrolyte membranes.

Electrochimica Acta published new progress about Battery anodes. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Name: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Jianwei published the artcileArtificial Single-Ion Conducting Polymer Solid Electrolyte Interphase Layer toward Highly Stable Lithium Anode, Category: alcohols-buliding-blocks, the main research area is artificial single ion conducting artificial electrolyte interphase lithium anode.

Lithium (Li) as one of the most promising anode materials for the next-generation batteries was unfortunately plagued by the inevitable Li dendrite growth and the dynamically destroy/reconstruction of the unstable native solid electrolyte interphase (SEI) layer, which can severely affect the specific capacity and lifespan of lithium batteries, limiting the practical application of the Li anode. In this work, a single ion conducting artificial polymer SEI layer is designed on the surface of the Li anode. The fabricated SEI layer shows high ionic conductivity and lithium transference number, which is beneficial for inducing homogeneous Li deposition, effectively suppressing the nucleation and growth of dendrite. Moreover, the uniform and stable SEI layer with a well-designed network structure can availably protect the Li anode from directly contacting with the electrolyte, reducing the related side reactions and effectually limit the addnl. consumption of the active Li and electrolyte. The sym. Li cells can cycle stably over 1200 h without short-circuit at the current/capacity densities of 1 (1 mAh/cm2) and 5 mA/cm2 (5 mAh/cm2). The assembled LiFePO4/LPEDV-Li cells exhibit high capacity retention ≤ 81.3% after 2400 cycles at the high rate of 8 C. Therefore, the designed artificial SEI layer with excellent properties presents a high application potential in stabilizing the Li anode.

ACS Applied Energy Materials published new progress about Battery anodes. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts