Category: 92093-23-7

Abdul Waseem, Malik published the artcileCatalyst Free Selective Monobenzoylation of Diols with Benzoyl Cyanide: A Robust and Regioselective Strategy, COA of Formula: C8H9BrO2, the main research area is diol polyol benzoyl cyanide regioselective chemoselective monobenzoylation catalyst free.

A general and robust strategy for regio- and chemoselective benzoylation of diols and polyols was developed under catalyst-free reaction conditions. This approach is highly flexible in generating a diverse range of 1,2-, 1,3-, and 1,4-monobenzoylated-adducts in excellent yields without the involvement of expensive catalysts. Collectively, these results have implications in reducing the burden of cost and toxicity associated with the catalysts used in earlier methods.

ChemistrySelect published new progress about Benzoylation, regioselective. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, COA of Formula: C8H9BrO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fischer, Christoph S. published the artcileEnhanced Brightness Emission-Tuned Nanoparticles from Heterodifunctional Polyfluorene Building Blocks, Product Details of C8H9BrO2, the main research area is enhanced brightness emission tuned nanoparticle heterodifunctional polyfluorene building block.

Three-coordinate complexes (bromo)[4-(2,2-dimethyl-1,3-dioxolan-4-yl)-phenyl](tri-tert-butyl-phosphine)palladium (1) and (bromo){4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}(tri-tert-butyl-phosphine)palladium (2) were used to initiate Suzuki-Miyaura chain growth polymerization of 7′-bromo-9′,9′-dioctyl-fluoren-2′-yl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (3). The polymerization was optionally terminated by end-capping with red-emitting N-(2-ethylhexyl)-1,6-bis(4-tert-octylphenoxy)-9-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-perylene-3,4-dicarboximide. Heterodisubstituted polyfluorenes of adjustable mol. weights between 5 × 103 and 1.0 × 104 g mol-1 and narrow mol. weight distribution (Mw/Mn < 1.2), bearing precisely one or two hydroxyl groups on one chain end and optionally a dye-label on the opposite end, were obtained virtually devoid of any side-products. Covalent attachment of polyethylene glycol (Mn = 2 × 103 g mol-1) to the reactive end groups yielded amphiphilic block copolymer, which afforded stable nanoparticles with diameters in the range of 25-50 nm when dispersed in water. These particles exhibited a bright fluorescence emission with quantum yields as high as Φ = 84%, which could optionally be tuned to longer wavelengths by energy transfer to the perylene monoimide dye. The heterodifunctional nature of these polyfluorenes is crucial for a bright and enduring fluorescence brightness as revealed by comparison to nanoparticles containing phys. mixed dye. Further addition of terrylene diimide dye to the nanoparticles of perylene-end-capped polyfluorene block copolymers allows for an energy cascade resulting in emission exclusively in the deep red and near-IR regime. Journal of the American Chemical Society published new progress about Fluorescence. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Product Details of C8H9BrO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pawliczek, Martin published the artcileAlkylative kinetic resolution of vicinal diols under phase-transfer conditions: a chiral ammonium borinate catalysis, Quality Control of 92093-23-7, the main research area is alc benzyloxy allyloxy asym synthesis; vicinal diol enantioselective regioselective phase transfer alkylative kinetic resolution.

Enantioselective synthesis of alcs. I [R1 = Ph, 2-MeC6H4, cyclohexyl, etc.; R2 = Ph, 2-MeC6H4, 2-naphthyl, (E)-PhCH:CH, etc.] and II (R3 = Ph, 4-FC6H4, 3-thienyl, etc.; R4 = Me, CH2:CHCH2) via alkylative kinetic resolution of vicinal diols R1CH(OH)CH2OH or R3R4C(OH)CH2OH, resp., with allylic or benzylic bromides realized by cooperative use of a chiral quaternary ammonium salt and an achiral borinic acid is reported. In addition, a catalytic regioselective alkylation of a secondary alc. in the presence of an unprotected primary one was presented, emphasizing the unique selectivity and potential of this ammonium borinate catalysis.

Chemical Science published new progress about Alkylation catalysts, stereoselective. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Quality Control of 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hirose, Keiji published the artcileEnantioselective complexation of phenolic crown ethers with chiral aminoethanol derivatives: effects of substituents of aromatic rings of hosts and guests on complexation, Quality Control of 92093-23-7, the main research area is enantioselective complexation phenolic crown ether chiral aminoethanol substituent effect.

Optically active azophenolic crown ethers having Ph groups substituted at the resp. para-position were prepared and their association constants with chiral aminoethanol derivatives, including 2-amino-2-phenylethanols having an electron-donating or an electron-withdrawing group, were determined in chloroform by means of UV-vis titration methods. The enantioselectivities of these crown ethers are estimated from the ratio of the association constants KR/KS and the effect of aromatic substituents of both hosts and guests on the binding abilities and enantioselectivities is discussed. The structures of the complexes were investigated on the basis of the 1H NMR and UV-vis spectra.

Perkin 2 published new progress about Chiral recognition. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Quality Control of 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kurapati, Sathish Kumar published the artcilecis-Dioxomolybdenum(VI) complexes with unsymmetric linear tetradentate ligands: syntheses, structures and bromoperoxidase activities, SDS of cas: 92093-23-7, the main research area is dioxomolybdenum hydroxyethylamino substituted phenol complex preparation electrochem; aralkyl bromide preparation dioxomolybdenum hydroxyethylamino substituted phenol catalyst; oxidative bromination dioxomolybdenum hydroxyethylamino substituted phenol catalyst; crystal structure dioxomolybdenum hydroxyethylamino ethylamino methyl substituted phenol complex.

Reactions of [MoO2(acetylacetonate)2], 2-((2-(2-hydroxyethylamino)ethylamino)methyl)-4-R-phenols (H2Ln, n = 1 – 5 for R = H, Me, OMe, Cl and Br, resp.) and KOH in 1:1:2 mol ratio in methanol afford a series of complexes having the general formula cis-[MoO2(Ln)] (1-5) in 81-86% yields. The complexes have been characterized using elemental anal., spectroscopy (IR, UV-visible, and 1H NMR, 13C NMR and 13C-DEPT NMR) and electrochem. measurements. The mol. structures of 1-4 have been determined using single-crystal x-ray crystallog. In each of 1-4, the ONNO-donor 6,5,5-membered fused chelate rings forming (Ln)2- and the two mutually cis oxo groups assemble a distorted octahedral N2O4 coordination sphere around the metal center. In the crystal lattice, each of 1-4 forms a one-dimensional infinite chain structure via intermol. N-H···O hydrogen bonding interactions. In cyclic voltammograms, the diamagnetic complexes display an irreversible metal-centered reduction in the potential range -0.73 to -0.88 V (vs. Ag/AgCl). The physicochem. data are consistent with a very similar gross mol. structure for all of 1-5. All the complexes exhibit decent bromoperoxidase activities and are also able to effectively catalyze benzoin and methyl(phenyl)sulfide oxidation reactions.

Applied Organometallic Chemistry published new progress about Aralkyl bromides Role: SPN (Synthetic Preparation), PREP (Preparation). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, SDS of cas: 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 92093-23-7, 1-(4-Bromophenyl)ethane-1,2-diol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Safety of 1-(4-Bromophenyl)ethane-1,2-diol, blongs to alcohols-buliding-blocks compound. Safety of 1-(4-Bromophenyl)ethane-1,2-diol

Alternative preparation of chiral 71rans-Lambda/-[2-(4-bromophenyl)cyclopropyl]-2- propanesulfonamide Enantiomer 1 and Enantiomer 2 EPO enantiomer 2enantiomer 1 Intermediate 7 Intermediate 7 enantiomer 2 Enantiomer 1 Enantiomer 2 trans trans; Intermediate 9, Enantiomer 1: chiral 2-(4-bromophenyl)oxirane Enantiomer 1; A 50OmL round bottom flask, equipped with magnetic stirrer, was charged with 10OmL of 1BuOH, 10OmL of water and of AD-mix-beta(30.6g). Stirring at room temperature produced two clear phases; the lower aqueous one appeared bright yellow. The mixture was cooled to 00C whereupon some of the dissolved salts precipitated. 4-Br-styrene (4g, 21.85mmol) was added at once and the heterogeneous slurry was stirred vigorously at 00C for 3h. While the mixture was stirred at 00C, solid sodium sulfite (32.8g) was added and the mixture was allowed to warm to room temperature and stirred for 1h. 20OmL DCM was added to the reaction mixture and after separation of the layers the aqueous one was further extracted with DCM (3x10OmL). Combined organic extracts were dried over Na2SO4 and evaporated to dryness to get 4.9g of crude material as a colourless thick oil.3.9g of this oil (17.97mmol) were dissolved in dry DCM 5OmL, under nitrogen. To this solution trimethylorthacetate (2.962mL, 23.27mmol) was added and the mixture cooled down to O0C. TMS-CI (2.964mL, 23.36mmol) was added dropwise and the reaction mixture left reacting for 1.5h. The volatiles were evaporated and the residue was dissolved in MeOH, treated with K2CO3 (3.1 g) and stirred vigorously at room temperature for 3h. The suspension was filtered, the solid was washed with DCM and the filtrate was evaporated in a rotary evaporator at room temperature under EPO vacuum to get crude title material (3.9g) that was purified by SiO2 flash chromatography eluting with petroleum ether/Et2O from 95/5 to 90/10. Evaporation of the solvent afforded title material, 2.95g, as a colourless oil that became a waxy solid in the fridge. NMR (CDCI3): 7.49 (d,2H), 7.13 (d, 2H), 3.84 (dd, 1 H), 3.13 (dd, 1 H), 2.77 (dd, 1 H). Chiral HPLC: ee 98.6% Analytical Chiral HPLC conditions: column: CHIRALPAK AS-H (25×0.46 cm) mobile phase: n-Hexane/Ethanol 95/5% v/v flow rate: 1 ml/minUV wavelength range: 200-400 nm Rt Enantiomer 1 : 6.1 min 99.3 a/a% Rt Enantiomer 2: 8.5min 0.7 a/a%.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,92093-23-7, 1-(4-Bromophenyl)ethane-1,2-diol, and friends who are interested can also refer to it.

Reference:
Patent; GLAXO GROUP LIMITED; WO2006/87169; (2006); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of 92093-23-7 ,Some common heterocyclic compound, 92093-23-7, molecular formula is C8H9BrO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: A diol 6c or 6d or 6e (2 equiv) and PPTS (0.1 equiv) was added to a toluene (25.0 mL/1 mmol of substrate) solution of a substituted-4,4-dimethoxycyclohexa-2,5-dienone 5a or 5b (1 equiv) at room temperature. After stirring at 40 C for 18 h, the reaction mixture was quenched by the addition of saturated aqueous NaHCO3 and the product was extracted with ethyl acetate three times. The combined organic extracts were washed with brine, dried over anhydrous magnesium sulphate, filtered, and concentrated under reduced pressure. The residue was purified by preparative TLC to give the title compound.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,92093-23-7, its application will become more common.

Reference:
Article; Fuse, Shinichiro; Inaba, Kennichi; Takagi, Motoki; Tanaka, Masahiro; Hirokawa, Takatsugu; Johmoto, Kohei; Uekusa, Hidehiro; Shin-ya, Kazuo; Takahashi, Takashi; Doi, Takayuki; European Journal of Medicinal Chemistry; vol. 66; (2013); p. 180 – 184;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts