Category: 699-12-7

Major, Mate M.; Balogh, Szabolcs; Simon, Jozsef; Bakos, Jozsef; Farkas, Gergely published the artcile< New chiral thioether-phosphite ligands and their rhodium-coordination chemistry: steric and electronic properties, dynamic processes and application in catalysis>, Safety of 2-(Phenylthio)ethanol, the main research area is rhodium thioether phosphite chiral BINOL ester complex preparation; asym hydrogenation catalyst rhodium thioether BINOL phosphite cyclooctadiene complex.

Thioether-phosphite ligands (S)-BINOL-PO(CH2)nSPh (SP’s, n = 2, 3; BINOL-H2 = 1,1′-binaphthyl-2,2′-diol, H8-1,1′-binaphthyl-2,2′-diol) with axially chiral binaphthyl or 5,5′,6,6′,7,7′,8,8′-octahydrobinaphthyl moiety and their [Rh(COD)(SP)]BF4 complexes have been synthesized to study their coordination chem. and catalytic features and to compare them to those of the structurally analogous phosphine-phosphites (S)-BINOL-PO(CH2)nPPh2 (PP’s). NMR exchange studies on [Rh(COD)(SP)]BF4 complexes showed selective 1,5-cyclooctadiene dynamics. Firm evidence has been found that this fluxional process involves dissociation of the Rh-sulfur bond. Based on in situ NMR studies, SP ligands can form two types of bis-ligated species at ligand-to-metal ratio higher than 1. Unlike bis-ligated phosphine-phosphite complexes, bis-ligated thioether-phosphite Rh-complexes can efficiently catalyze asym. hydrogenation reactions due to their distinct coordination chem.

Journal of Coordination Chemistry published new progress about Amino acids Role: SPN (Synthetic Preparation), PREP (Preparation). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Safety of 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Alfonzo, Edwin; Hande, Sudhir M. published the artcile< α-Heteroarylation of Thioethers via Photoredox and Weak Bronsted Base Catalysis>, Safety of 2-(Phenylthio)ethanol, the main research area is Heteroarylation thioether photoredox weak Bronsted base catalysis; Classical Minisci Reaction with Thioethers.

We report the C-H activation of thioethers to α-thio alkyl radicals and their addition to N-methoxyheteroarenium salts for the redox-neutral synthesis of α-heteroaromatic thioethers. Studies are consistent with a two-step activation mechanism, where oxidation of thioethers to sulfide radical cations by a photoredox catalyst is followed by α-C-H deprotonation by a weak Bronsted base catalyst to afford α-thio alkyl radicals. Further, N-methoxyheteroarenium salts play addnl. roles as a source of methoxyl radical that contributes to α-thio alkyl radical generation and a sacrificial oxidant that regenerates the photoredox catalytic cycle.

Organic Letters published new progress about Bronsted bases Role: CAT (Catalyst Use), USES (Uses). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Safety of 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bai, Renren; Zhu, Junlong; Bai, Ziqiang; Mao, Qing; Zhang, Yingqian; Hui, Zi; Luo, Xinyu; Ye, Xiang-Yang; Xie, Tian published the artcile< Second generation β-elemene nitric oxide derivatives with reasonable linkers: potential hybrids against malignant brain glioma>, Computed Properties of 699-12-7, the main research area is beta elemene nitric oxide malignant brain glioma antitumor; NO donor; anti-tumour; malignant glioma; natural product; β-Elemene.

Elemene is a second-line broad-spectrum anti-tumor drug that has been used in China for more than two decades. However, its main anti-tumor ingredient, β-elemene, has disadvantages, including excessive lipophilicity and relatively weak anti-tumor efficacy. To improve the anti-tumor activity of β-elemene, based on its minor mol. weight character, we introduced furoxan nitric oxide (NO) donors into the β-elemene structure and designed six series of new generation β-elemene NO donor hybrids. The synthesized compounds could effectively release NO in vitro, displayed significant anti-proliferative effects on U87MG, NCI-H520, and SW620 cell lines. In the orthotopic glioma model, compound significantly and continuously suppressed the growth of gliomas in nude mice, and the brain glioma of the treatment group was markedly inhibited (>90%). In short, the structural fusion design of NO donor and β-elemene is a feasible strategy to improve the in vivo anti-tumor activity of β-elemene.

Journal of Enzyme Inhibition and Medicinal Chemistry published new progress about Amidation. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Computed Properties of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Moeini, Nazanin; Molaei, Somayeh; Ghadermazi, Mohammad published the artcile< Selective oxidation of sulfides and synthesis of 5-substituted 1H-tetrazoles on Ce (III) immobilized CoFe2O4 as a magnetically separable, highly active, and reusable nanocatalyst>, Safety of 2-(Phenylthio)ethanol, the main research area is cobalt iron oxide nanocatalyst cerium immobilized amino glycol preparation; tetrazole green preparation; nitrile sodium azide cobalt iron oxide nanocatalyst cerium immobilized; sulfoxide green preparation; sulfide oxidation cobalt iron oxide nanocatalyst cerium immobilized.

Reactions of CoFe2O4 magnetic nanoparticles supported ligands, 2-amino-2-methyl-1,3-propanediol (Amino glycol), with cerium salts provided the resp. anchored complex CoFe2O4 @Amino glycol/Ce. The nanocatalyst was characterized perfectly using thermogravimetric analyzes, FT-IR spectroscopy, SEM, energy-dispersive X-ray inductively coupled plasma optical emission spectroscopy vibrational sample magnetometry and powder X-ray diffraction. CoFe2O4 magnetic nanoparticles supported ligands with cerium salts afforded active catalysts for the synthesis of 5-substituted 1H-tetrazoles I [R = Ph, 2-ClC6H4, Bn, etc.] via reaction of nitriles and sodium azide/oxidation of sulfides RSR1 [R = Ph, n-Pr, Et, etc.; R1 = Me, Bn, Ph, etc.] using Me Ph sulfide with H2O2 as oxidant at mild reaction conditions in the green medium under optimized conditions. The ligand and metal atom identity influenced the catalytic activity of the nanocatalyst. The immobilized complexes were easily collected via an external magnetic field and further reused at least 6 times without significant loss of catalytic activity and selectivity.

Research on Chemical Intermediates published new progress about Green chemistry. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Safety of 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jani, Muhammed Ali; Bahrami, Kiumars published the artcile< Synthesis of 5-substituted 1H-tetrazoles and oxidation of sulfides by using boehmite nanoparticles/nickel-curcumin as a robust and extremely efficient green nanocatalyst.>, Recommanded Product: 2-(Phenylthio)ethanol, the main research area is nickel anchored curcumin functionalized boehmite nanocatalyst preparation; benzonitrile sodium azide nickel catalyst cycloaddtion; tetrazole preparation green chem; sulfide nickel catalyst oxidation; sulfoxide preparation green chem.

Nickel-anchored curcumin-functionalized boehmite nanoparticles (BNPs@Cur-Ni)nanocatalyst was synthesized and well-characterized by using Fourier transform IR (FT-IR), transmission electron microscopy (TEM), SEM (SEM), energy dispersive X-ray (EDX), X-ray mapping, thermogravimetric anal. (TGA), DTA (DTA), Brunauer-Emmett-Teller (BET), X-ray diffraction (XRD), and inductively coupled plasma optical emission spectroscopy (ICP-OES). The synthesis of 5-substituted 1H-tetrazoles and the oxidation of sulfides were conducted by BNPs@Cur-Ni with excellent turnover number (TON) and turnover frequency (TOF) outcomes. Also, the catalyst was reused for several sequential runs without Ni leaching or decreasing in reaction yield. Utilizing the curcumin and boehmite with a natural source as well as poly(ethylene glycol) (PEG) as a solvent in this simple protocol can be based on green chem. rules.

Applied Organometallic Chemistry published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Recommanded Product: 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Hai-Lou; Lian, Chen; Yin, Da-Peng; Yang, Guo-Yu published the artcile< Three Zr(IV)-Substituted Polyoxotungstate Aggregates: Structural Transformation from Tungstoantimonate to Tungstophosphate Induced by pH>, Computed Properties of 699-12-7, the main research area is zirconium antimony polyoxotungstate complex preparation oxidation catalyst thermal stability; crystal structure zirconium antimony polyoxotungstate complex.

Three novel Zr-substituted polyoxotungstate aggregates [H2N(CH3)2]7NaH2[Zr2Sb2O3(A-α-PW9O34)2]·16H2O (1), [H2N(CH3)2]6H12[ZrSb4(OH)O2(A-α-PW8O32)(A-α-PW9O34)]2·33H2O (2), and [H2N(CH3)2]4Na11.5H4.5[Zr4W8Sb4P5O49(OH)5(B-α-SbW9O33)2]·53H2O (3) have been made in hydrothermal reactions of the [B-α-SbW9O33]9- precursor with Zr4+ cations and PO43- anions in the presence of dimethylamine hydrochloride and sodium acetate buffer (pH = 4.8) and structurally characterized. Different pH values induce structural transformation from tungstoantimonate (TA) to tungstophosphate (TP). 1 Is a di-Zr-substituted sandwich-type TP, the tetranuclear heterometallic [Zr2Sb2O3]8+ entity sandwiched by two [A-α-PW9O34]9- moieties. 2 Is a double sandwich-type structure, which can be perceived as two equivalent sandwiched [Sb3(PW8O32)(PW9O34)]11- further sandwiching one [Sb2Zr2(OH)2O4]4+ core to form a novel large-size sandwich-type architecture. Different from 1 and 2, 3 is a tetra-Zr-substituted sandwiched configuration, in which two [B-α-SbW9O33]9- fragments sandwich a unique 21-core Sb-P-W-Zr oxo cluster ({Zr4W8Sb4P5}). Furthermore, the catalytic oxidation of aromatic thioethers by 3 as the heterogeneous catalyst has been investigated, showing high conversion and remarkable selectivity as well as excellent recyclability.

Inorganic Chemistry published new progress about Crystal structure. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Computed Properties of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Bin; Elder, W. Zachary; Miyake, Garret M. published the artcile< Scalable and Phosphine-Free Conversion of Alcohols to Carbon-Heteroatom Bonds through Blue-Light Promoted Iodination Reaction>, Reference of 699-12-7, the main research area is alc scalable carbon heteroatom bond blue light iodination.

A simple route toward the diverse conversion of alcs. via an SN2 pathway, in which blue light promoted iodination is used to form alkyl iodide intermediates from simple unreactive alcs. ROH [R = hex-5-yn-1-yl, 2-(1H-indol-3-yl)ethyl, cyclopentyl, etc.] was reported. The scope of the process tolerates a range of nucleophiles R1H [R1 = CN, (4-bromophenyl)carbonyloxidanyl, quinolin-6-yloxidanyl, (furan-2-yl)carbonyloxy, etc.] to construct C-N, C-O, C-S, and C-C bonds. Furthermore, this method can be used for the preparation and late stage functionalization of pharmaceuticals, as highlighted by the synthesis of thiocarlide, butoxycaine, and pramoxine.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Reference of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zohrevandi, Mina; Mozafari, Roya; Ghadermazi, Mohammad published the artcile< A nickel nanoparticle engineered CoFe2O4/SiO2-NH2@carboxamide composite as a novel scaffold for the oxidation of sulfides and oxidative coupling of thiols>, Electric Literature of 699-12-7, the main research area is nickel carboxamide complex supported cobalt ferrite nanoparticle catalyst preparation; sulfoxide green preparation; sulfide oxidation nickel carboxamide complex catalyst; disulfide green preparation; thiol oxidative coupling nickel carboxamide complex catalyst.

A new Ni-carboxamide complex supported on CoFe2O4 nanoparticles (CoFe2O4/SiO2-NH2@carboxamide-Ni) was prepared The carboxamide host material unit generated cavities that stabilized the nickel nanoparticles effectively and prevented the aggregation and separation of these particles on the surface. This compound was appropriately characterized using FT-IR spectroscopy, FE-SEM, ICP-OES, EDX, XRD, TGA anal., VSM and X-ray at. mapping. The catalytic oxidation of sulfides to give sulfoxides RS=OR1 [R = Ph, 4-BrC6H4, Bn, etc.; R1 = H, Me, Ph, etc.] and oxidative coupling of thiols to give disulfides R2S-SR2 [R2 = Ph, 4-MeC6H4, Bn, etc.] in the presence of the designed catalyst was explored as a highly selective catalyst using hydrogen peroxide as a green oxidant. The easy separation, simple workup, excellent stability of the nanocatalyst, short reaction times, non-explosive materials as well as appropriate yields of the products were some outstanding advantages of this protocol.

RSC Advances published new progress about Disulfides Role: SPN (Synthetic Preparation), PREP (Preparation). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Electric Literature of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mahdian, Abolfazl; Ardakani, Mehdi Hatefi; Heydari-Bafrooei, Esmaeil; Saeednia, Samira published the artcile< Oxo-vanadium(IV) unsymmetrical Schiff base complex immobilized on γ-Fe2O3 nanoparticles: A novel and magnetically recoverable nanocatalyst for selective oxidation of sulfides and oxidative coupling of thiols>, Application In Synthesis of 699-12-7, the main research area is thioether Schiff base complex catalyst selective oxidation green chem; thiol supported oxovanadium Schiff base complex catalyst oxidative coupling; iron oxide support oxovanadium Schiff base complex preparation crystallinity.

An unsym. salen-type oxo-vanadium(IV) complex, [VO(salenac-OH)] (salenac-OH = [9-(2′,4′-dihydroxyphenyl)-5,8-diaza-4-methylnona-2,4,8-trienato](-2)), was synthesized and covalently immobilized on the surface of magnetic γ-Fe2O3 nanoparticles. The resulting γ-Fe2O3@[VO(salenac-OH)] nanoparticles were characterized by several techniques including Fourier transform IR (FT-IR) spectroscopy, X-ray diffraction (XRD), scanning and transmission electron microscopies (SEM and TEM), energy-dispersive X-ray (EDX) spectroscopy, vibrating sample magnetometry (VSM), thermal gravimetric anal. (TGA), inductively coupled plasma (ICP), and elemental anal. The prepared γ-Fe2O3@[VO(salenac-OH)] nanoparticle was utilized as an efficient catalyst for selective oxidation of sulfides to sulfoxides using 30% H2O2 as oxidant and oxidative coupling of thiols into disulfides with urea/H2O2 (UHP) as an oxidizing reagent. The products were achieved with good to excellent yields at room temperature with no over-oxidation of sulfoxides and disulfides to unexpected byproducts. This catalyst were magnetically recovered by applying an external magnet and reused for five continuous cycles in both oxidation reactions without a significant loss in its catalytic activity. Furthermore, the FT-IR spectrum and XRD pattern of the recovered catalyst showed no critical change to those of the fresh one.

Applied Organometallic Chemistry published new progress about Crystallinity. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Application In Synthesis of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molaei, Somayeh; Tamoradi, Taiebeh; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash published the artcile< Highly Efficient Oxidative Coupling of Thiols and Oxidation of Sulfides in the Presence of MCM-41@Tryptophan-Cd and MCM-41@Tryptophan-Hg as Novel and Recoverable Nanocatalysts>, Application of C8H10OS, the main research area is thiol sulfide oxidative coupling silica tryptophan cadmium mercury nanocatalyst.

Abstract: Two heterogeneous catalysts, MCM-41@Tryptophan-Cd and MCM-41@Tryptophan-Hg, were synthesized by immobilization of Cd or Hg complexes on MCM-41 as novel, efficient, recoverable and stable nanocatalysts for Oxidation of sulfides to sulfoxides and oxidative coupling of thiols into their corresponding disulfides. These functionalized complexes were characterized by FT-IR spectroscopy, thermogravimetric anal. (TGA), powder X-ray diffraction (XRD) and N2 adsorption-desorption isotherms. The designed catalysts successfully oxidized a variety of sulfides and thiols with short reaction times in high to excellent yields at room temperature and recovered for several times without significant loss of their catalytic activity. Graphical Abstract: Synthesis of Cd and Hg tryptophan complexes immobilized on to surface of mesoporous MCM-41 under mild reaction conditions has been presented. After characterization of these catalysts, their catalytic activity has been investigated for the synthesis of sulfoxide and disulfides derivatives [Figure not available: see fulltext.].

Catalysis Letters published new progress about Adsorption. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Application of C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts