Category: 627-27-0

Zhang, Lianglin; Lin, Shuwei; Li, Yi; Li, Baozong; Yang, Yonggang published the artcile< Ala-Ala dipeptides with a semi-perfluoroalkyl chain: Chirality driven molecular packing difference and self-assembly driven chiral transfer>, Reference of 627-27-0, the main research area is perfluoroalkyl dipeptide synthesis self assembly helical conformation chirality VCD; solid phase peptide synthesis acylation self assembly xerogel nanoribbon; supramol aggregate gelation crystal structure mol packing; mol structure HOMO LUMO perfluoroalkylated dipeptide solubility.

Four Ala-Ala dipeptides with a semi-perfluoroalkyl chain were synthesized. The intermol. hydrogen bonding among amide groups and carboxyl groups as well as the hydrophobic association of semi-perfluoroalkyl chains drove the self-assembly of dipeptides. Homochiral dipeptides were able to self-assemble into coiled nanoribbons in a mixed solvent of DMSO/H2O (5/5, volume/volume), while entangled twisted nanofibers formed for heterochiral ones in a mixed solvent of DMSO/H2O (4/6, volume/volume). The handedness of self-assemblies and the stacking chirality of phenylene groups were controlled by the chirality of the alanine residue at the C-terminal. The vibration CD investigation indicated that the helicity of the semi-perfluoroalkyl chain was controlled by the handedness of dipeptide self-assemblies. The X-ray diffraction study showed that homochiral and heterochiral dipeptides underwent distinct mol. packing during the self-assembly. Our results clearly demonstrated that, through supramol. self-assembly, the chirality transferred from the amino acid building block to the self-assemblies and eventually to the semi-perfluoroalkyl chain.

New Journal of Chemistry published new progress about Acylation. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Reference of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jarret, Maxime; Abou-Hamdan, Hussein; Kouklovsky, Cyrille; Poupon, Erwan; Evanno, Laurent; Vincent, Guillaume published the artcile< Bioinspired Early Divergent Oxidative Cyclizations toward Pleiocarpamine, Talbotine, and Strictamine>, Synthetic Route of 627-27-0, the main research area is talbotine formal synthesis oxidative cyclization.

Toward the mavacurane and akuammilane monoterpene indole alkaloids, we developed divergent oxidative couplings between the indole nucleus (at N1 or C7) and the C16-malonate of a common tricyclic model related to strictosidine according to a biosynthetic hypothesis postulated by Hesse and Schmid. These oxidative cyclizations led selectively to the formation of the N1-C16 bond of pleiocarpamine or to the C7-C16 bond of strictamine. We were then able to obtain the scaffold I of talbotine.

Organic Letters published new progress about Enantioselective synthesis. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Synthetic Route of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jiang, Siyuan; Liu, Yufei; Zou, Xiaoyu; He, Min; Zhang, Kai; Xu, Guomin; Qin, Shuhao published the artcile< Synthesis and application of new macromolecular hindered phenol antioxidants of polyamide 6>, Product Details of C4H8O, the main research area is nylon 6 antioxidant hydroxyphenyl propionate phenylmaleimide alternting copolymer preparation.

The two macromol. antioxidants, P(3,5-di-tert-butyl-4-hydroxy cinnamic acid-N-phenylmaleimide) (PCN) and P(3-butene-1-yl-3,5-di-tert-Bu -4-hydroxyphenyl propionate-N-phenylmaleimide) (PPN) were designed and synthesized via free radical copolymerization The structures of the resulting PCN and PPN antioxidants were characterized by Fourier transform IR spectroscopy, NMR spectroscopy (1H NMR), and gel permeation chromatog. In addition, the effect of the two macromol. antioxidants on the thermal oxidation aging resistance of polyamide 6 (PA6) was studied. According to the anal. of differential scanning calorimetry, thermogravimetric anal., dynamic mech. anal., dynamic viscosity, and the mech. property of PA6 and its blends, these two types of macromol. antioxidants protected the mol. chain of PA6 from breaking, protected the crystallization of PA6 and maintained the stability of PA6 crystal form, improved the activation energy of thermal degradation and thermal stability of PA6, enhanced the strength and elasticity of PA6 and maintained the mech. properties of PA6 during aging to a certain extent.

Journal of Applied Polymer Science published new progress about Antioxidants. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Product Details of C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Mengxun; Chen, Tie; Fang, Shisong; Wu, Weihua; Wang, Xin; Wu, Haiqiang; Xiong, Yongai; Song, Jun; Li, Chenyang; He, Zhendan; Lee, Chi-Sing published the artcile< Peroxide- and transition metal-free electrochemical synthesis of α,β-epoxy ketones>, Quality Control of 627-27-0, the main research area is epoxy ketone preparation antitumor activity diastereoselective green chem electrochem.

A novel electrochem. method for the synthesis of α,β-epoxy ketones I (R = 2-methylphenyl, 3-iodophenyl, 2,3-dihydro-1-benzofuran-6-yl, etc.; R1 = 4-methylphenyl, 5-fluoro-2-methoxyphenyl, naphthalen-2-yl, etc.) is reported. With KI as the redox mediator, Me ketones RC(O)CH3 reacted with aldehydes R1CHO under peroxide- and transition metal-free electrolytic conditions and afforded α,β-epoxy ketones I in one pot (36 examples, 52-90% yield). This safe and environmental-friendly method has a broad substrate scope and can readily provide a variety of α,β-epoxy ketones I in gram-scales for evaluation of their anti-cancer activities.

Organic & Biomolecular Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Quality Control of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Yu-Feng; Mellah, Mohamed published the artcile< Samarium(II)-electrocatalyzed chemoselective reductive alkoxylation of phthalimides>, Safety of But-3-en-1-ol, the main research area is phthalimide alkanol samarium catalyst electrochem selective reductive alkoxylation; alkoxy isoindolinone preparation.

The unprecedented samarium electrocatalyzed reductive alkoxylation of phthalimides in a single step was presented. Under mild conditions, using electrogenerated Sm(II) with TMSCl (tri-Me chlorosilane), N-substituted 3-alkoxyl isoindolin-1-ones were isolated in good to excellent yields with high functional group tolerance.

Organic Chemistry Frontiers published new progress about Aliphatic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hess, Stephan N.; Mo, Xiaobin; Wirtz, Conny; Fuerstner, Alois published the artcile< Total Synthesis of Limaol>, Product Details of C4H8O, the main research area is limaol total synthesis Stille asym propargylation spirocyclization.

A nonthermodynamic array of four skipped methylene substituents on the hydrophobic tail renders limaol (I), a C40-polyketide of marine origin, unique in structural terms. This conspicuous segment was assembled by a two-directional approach and finally coupled to the polyether domain by an allyl/alkenyl Stille reaction under neutral conditions. The core region itself was prepared via a 3,3′-dibromo-BINOL-catalyzed asym. propargylation, a gold-catalyzed spirocyclization, and introduction of the southern sector via substrate-controlled allylation as the key steps.

Journal of the American Chemical Society published new progress about Diastereoselective synthesis. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Product Details of C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sudhakaran, Swetha; Taketoshi, Ayako; Siddiki, S. M. A. Hakim; Murayama, Toru; Nomura, Kotohiro published the artcile< Transesterification of Ethyl-10-undecenoate Using a Cu-Deposited V2O5 Catalyst as a Model Reaction for Efficient Conversion of Plant Oils to Monomers and Fine Chemicals>, Safety of But-3-en-1-ol, the main research area is transesterification ethyl undecenoate copper vanadium oxide catalyst plant oil.

Transesterification of ethyl-10-undecenoate (derived from castor oil) with 1,4-cyclohexanedimethanol over a recyclable Cu-deposited V2O5 catalyst afforded 1,ω-diene, the corresponding cyclohexane-1,4-diylbis(methylene) bis(undec-10-enoate), a promising monomer for the synthesis of biobased polyesters, in an efficient manner. Deposition of Cu plays an important role in proceeding the reaction with high selectivity, and both the activity and the selectivity are preserved for five recycled runs by the addition of the substrates. The present catalyst was effective for transesterification with other alcs., especially primary alcs., demonstrating a possibility of using this catalyst for efficient conversion of plant oil to various fine chems.

ACS Omega published new progress about Castor oil Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhai, Pingan; Li, Wenhui; Lin, Jianying; Huang, Shuangping; Gao, Wenchao; Li, Xing published the artcile< N-Alkyl nitrones as substrates for access to N-aryl isoxazolidines via a catalyst-free one-pot three-component reaction with nitroso compounds and olefins>, Computed Properties of 627-27-0, the main research area is nitrosobenzene methylmethanimine oxide ethene catalyst free three component reaction; phenyl isoxazoldine preparation regioselective chemoselective diastereoselective.

N-Alkyl nitrones were used as the starting materials to construct various N-aryl isoxazolidines, via a catalyst-free one-pot three-component reaction with nitroso compounds and olefins. The mechanism investigations indicated that the in-situ formation of N-aryl nitrones from the reaction of N-alkyl nitrones and nitrosoarenes was the key step. The protocol features broad substrate scope, good to excellent chemo-, regio- and diastereo-selectivities, and moderate to excellent yields for most substrates.

Organic Chemistry Frontiers published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Computed Properties of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhao, Huaibo; McMillan, Alastair J.; Constantin, Timothee; Mykura, Rory C.; Julia, Fabio; Leonori, Daniele published the artcile< Merging Halogen-Atom Transfer (XAT) and Cobalt Catalysis to Override E2-Selectivity in the Elimination of Alkyl Halides: A Mild Route toward contra-Thermodynamic Olefins>, HPLC of Formula: 627-27-0, the main research area is Merging Halogen Atom Transfer Cobalt Catalysis Elimination Alkyl Halides.

We report here a mechanistically distinct tactic to carry E2-type eliminations on alkyl halides. This strategy exploits the interplay of α-aminoalkyl radical-mediated halogen-atom transfer (XAT) with desaturative cobalt catalysis. The methodol. is high-yielding, tolerates many functionalities, and was used to access industrially relevant materials. In contrast to thermal E2 eliminations where unsym. substrates give regioisomeric mixtures, this approach enables, by fine-tuning of the electronic and steric properties of the cobalt catalyst, to obtain high olefin positional selectivity. This unprecedented mechanistic feature has allowed access to contra-thermodn. olefins, elusive by E2 eliminations.

Journal of the American Chemical Society published new progress about Crystal structure. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, HPLC of Formula: 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Podrojkova, Natalia; Patera, Jan; Popescu, Radian; Skoviera, Jan; Orinakova, Renata; Orinak, Andrej published the artcile< Pyrolysis Degradation of Cellulose over Highly Effective ZnO and ZnO-CuO Nanocatalysts>, Recommanded Product: But-3-en-1-ol, the main research area is zinc copper oxide nanocatalyst cellulose pyrolysis degradation.

Pyrolysis of lignocellulosic biomass with the use of appropriative catalysts can lead to the production of high yields of fuels – bio-oils. Here, zinc oxide – copper oxide (ZnO-CuO) nanocatalysts were synthesized by solvothermal synthesis. High-angle annular dark-field imaging scanning transmission electron microscopy (HAADF-STEM), high-resolution transmission electron microscopy (HRTEM), and energy-dispersive X-ray spectroscopy (EDXS) results suggested that ZnO-CuO nanoparticles (D=23±5 nm) exhibit porous nanostructure. The pyrolytic degradation of cellulose using pyrolysis-gas chromatog.-mass spectrometry (Py-GC/MS) unit has been studied over ZnO and ZnO-CuO nanocatalysts at the temperature range 400-800 °C. The activation energy of ZnO-CuO (67.21 and 70.04 kJ/mol) was lower by 30 kJ/mol from the activation energy of clean ZnO and the calculated rate constants showed that the cellulose pyrolytic reaction is faster using ZnO-CuO catalyst. Nanoporous ZnO-CuO shifted the products maximum towards lower temperatures (< 500 °C), reduced the content of aldehydes at 400-500 °C and enhanced the overall product composition and bio-oil yield. Porous structure of ZnO nanocatalysts had a significant effect on the product selectivity and reaction mechanism of cellulose pyrolysis. ChemistrySelect published new progress about Acids Role: TEM (Technical or Engineered Material Use), USES (Uses). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts