Category: 627-27-0

Li, Yuanhao; Gu, Fan; Ding, Bingbing; Zou, Lei; Ma, Xiang published the artcile< Photo-controllable room-temperature phosphorescence of organic photochromic polymers based on hexaarylbiimidazole>, Synthetic Route of 627-27-0, the main research area is amorphous polymer photochromism room temperature phosphorescence.

Pure organic room-temperature phosphorescent (RTP) materials have been attracting widespread attention due to the unique properties and broad applications. However, RTP materials with the adjustable photochromic property are still a challenge. Based on this, two polymers containing hexaarylbiimidazole are strategically designed with dual emission of both fluorescence and phosphorescence. Furthermore, both polymers show sensitive photochromic responses from faint yellow to brown upon exposure to UV light This study can enrich pure organic luminescent systems and provide new ideas for functional RTP materials.

Science China: Chemistry published new progress about Phosphorescence. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Synthetic Route of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jones, Brad H.; Staiger, Chad; Powers, Jackson; Herman, Jeremy A.; Roman-Kustas, Jessica published the artcile< Selectively Depolymerizable Polyurethanes from Unsaturated Polyols Cleavable by Olefin Metathesis>, COA of Formula: C4H8O, the main research area is selectively depolymerizable polyurethane unsaturated polyol cleavable olefin metathesis; cycloalkenes; depolymerization; olefin metathesis; polyurethanes; ring-closing metathesis.

This communication describes a novel series of linear and crosslinked polyurethanes (PUs) and their selective depolymerization under mild conditions. Two unique polyols are synthesized bearing unsaturated units in a configuration designed to favor ring-closing metathesis (RCM) to five- and six-membered cycloalkenes. These polyols are co-polymerized with toluene diisocyanate to generate linear PUs and trifunctional hexamethylene- and diphenylmethane-based isocyanates to generate crosslinked PUs. The polyol design is such that the RCM reaction cleaves the backbone of the polymer chain. Upon exposure to dilute solutions of Grubbs’ catalyst under ambient conditions, the PUs are rapidly depolymerized to low mol. weight, soluble products bearing vinyl and cycloalkene functionalities. These functionalities enable further re-polymerization by traditional strategies for polymerization of double bonds. It is anticipated that this general approach can be expanded to develop a range of chem. recyclable condensation polymers that are readily depolymerized by orthogonal metathesis chem.

Macromolecular Rapid Communications published new progress about Depolymerization. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, COA of Formula: C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Cheng; Sun, Qiaoying; Rudolph, Matthias; Rominger, Frank; Hashmi, A. Stephen K. published the artcile< Gold-Catalyzed Regiodivergent Annulations of Diazo-Alkynes Controlled by Et3N(HF)3>, Name: But-3-en-1-ol, the main research area is ethyl aryl alkyl naphthoate regioselective preparation; phenyl ethyl diazo oxopropanoate annulation catalyst gold.

Selectivity control in catalytic carbene insertions was known to be dominated by the adjustment of both the electronic and steric properties of metal complexes. Herein, a conceptually distinct strategy that enables a regioselectivity switch for the gold-catalyzed carbohydroxylation of diazo-tethered alkynes controlled by the additive Et3N(HF)3 for synthesis of Et (aryl/alkyl)-naphthoates was I [R1 = OH, Ph, 4-MeC6H4, etc.; R2 = F, OH, Ph, etc.; R3 = H, 7-F, 7-MeO, etc.] reported. Depending on the reaction conditions, either direct carbohydroxylation was observed or Michael addition/1,2-shift of the quinoid carbene intermediate in the presence of a Bronsted acid was involved. In both cases, the reaction proceeded with high regioselectivity. An intramol. cascade fluorination process for the synthesis of aryl fluorides I [R1 = Ph, 4-MeC6H4, 2-naphthyl, etc.; R2 = F; R3 = H, 7-F, 7-MeO, etc.] in high yield, which could be triggered under inert conditions and the use of Et3N(HF)3 was described.

ACS Catalysis published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Name: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Varghese, Swapna; Rahmani, Raphael; Drew, Damien R.; Beeson, James G.; Baum, Jake; Smith, Brian J.; Baell, Jonathan B. published the artcile< Structure-Activity Studies of Truncated Latrunculin Analogues with Antimalarial Activity>, Quality Control of 627-27-0, the main research area is Plasmodium growth antimalarial latrunculin QSAR; Actin inhibitors; P. falciparum; heterocycles; latrunculin analogues; malaria; natural products.

Malarial parasites employ actin dynamics for motility, and any disruption to these dynamics renders the parasites unable to effectively establish infection. Therefore, actin presents a potential target for malarial drug discovery, and naturally occurring actin inhibitors such as latrunculins are a promising starting point. However, the limited availability of the natural product and the laborious route for synthesis of latrunculins have hindered their potential development as drug candidates. In this regard, we recently described novel truncated latrunculins, with superior actin binding potency and selectivity towards P. falciparum actin than the canonical latrunculin B. In this paper, we further explore the truncated latrunculin core to summarize the SAR for inhibition of malaria motility. This study helps further understand the binding pattern of these analogs in order to develop them as drug candidates for malaria.

ChemMedChem published new progress about Antimalarials. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Quality Control of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shen, Wenbo; Du, Bin; Zhuo, Haitao; Chen, Shaojun published the artcile< Recyclable and reprocessable epoxy-polyhedral oligomeric silsesquioxane (POSS)/mesogenic azobenzene/poly (ethylene-co-vinyl acetate) composites with thermal- and light-responsive programmable shape-memory performance>, SDS of cas: 627-27-0, the main research area is recyclable reprocessable epoxy polyhedral oligomeric silsesquioxane.

In this study, an Epoxy/POSS-liquid crystalline azobenzene-Poly (ethylene-co-vinyl acetate) (Epoxy/POSS-Azo-EVA) composite was prepared via the thermal curing of epoxy monomers and multi-functional thiol-containing Polyhedral oligomeric silsesquioxane (POSS) in an EVA matrix. The EVA matrix afforded the composite with shape memory performance. Epoxy/POSS polymer was uniformly dispersed in the matrix to act as a rigid skeleton, leading to the improvement of the mech. properties and shape memory performance of the composite. Liquid crystalline azobenzene as the photosensitive component provided the inner stress to render the composite film with photo-induced shape-deformation behavior under UV light. The composite film not only exhibited thermal- and light-responsive programmable shape-memory behavior stimulated by heat and light, but also was recyclable and reprocessable. Moreover, the recycled composite film was processed into different functional devices. A flexible photomech. device based on the recycled Epoxy/POSS-Azo-EVA composite film was fabricated, and the soft device deformed into a hook-shape under UV light and hooked an object whose weight is larger than that of the device. A smart wire was also prepared via assembling a stretched recycled Epoxy/POSS-Azo-EVA composite film and a copper foil by adhesive. The wire could control the status of a circuit via changing its shape under UV light and maintain the status after the removal of light. The functional devices described in this work only needed a short time of UV irradiation during a work cycle, and the devices still held the temporary shape in the absence of UV irradiation The recyclable and reprocessable Epoxy/POSS-Azo-EVA composite film in this work could provide a creative approach for the fabrication of novel photomech. devices and soft robotics with energy-saving, intelligence, recyclability, and sustainability.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Apparatus (functional). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, SDS of cas: 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Yong; Chen, Qi; Wang, Yuyu; Zhang, Qiang; Han, Qiuxia published the artcile< Fluorocarbon-assisted surface orientation of N-halamine groups on cellulose in supercritical CO2: An effective and eco-friendly approach for developing higher biocidability>, Safety of But-3-en-1-ol, the main research area is surface orientation halamine polysiloxane cellulose supercritical carbon dioxide; biocidal halamine polysiloxane coating cotton textile antibacterial.

Preferential segregation of N-halamine structure to top surface to better contact with bacteria is demonstrated to be an effective tactic for achievement of higher biocidability. 5-Allylbarbituric acid and its fluorinated derivative, formed by sacrificing a imide hydrogen to tether a 4-perfluorohexylbutyl segment via nucleophilic substitution, were synthesized and sep. attached to (50% methylhydrosiloxane)-dimethylsiloxane block copolymer (P(MHS-DMS)) via hydrosilylation. Chlorination of N-H bonds originating from barbituric acid produced two N-halamine polysiloxanes that were interpenetrated into cellulose to form coatings with similar morphol. and thickness. Although containing ∼50% less total content of chlorine than its nonfluorinated counterpart, polysiloxane with fluorinated pendants exerted faster inactivation against Staphylococcus aureus and Escherichia coli due to the orientation of its N-halamine groups on top surface with the assistance of the low-surface-tension 4-perfluorohexylbutyl segment as verified by depth profiling using angle-dependent XPS (ADXPS). Design biocide with proper surface segregation ability therefore paves a new way for improved antibacterial efficacy. The stability and rechargeability of the biocidability of the coatings are satisfactory under washing cycles, UV irrigation, and storage.

Applied Surface Science published new progress about Antibacterial agents. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Peng-Fei; Shu, Wei published the artcile< Orthogonal Access to α-/β-Branched/Linear Aliphatic Amines by Catalyst-Tuned Regiodivergent Hydroalkylations>, Application In Synthesis of 627-27-0, the main research area is amine preparation regioselective; chiral amine preparation regioselective enantioselective; alkenyl amine alkyl halide hydroalkylation metal catalyst; Amines; Chain Walking; Cobalt Catalysis; Hydroalkylations; Regiodivergent Reactions.

Herein, a catalyst-controlled synthesis of α-branched e.g., N-(1-phenylpentan-3-yl)benzamide, β-branched e.g., N-(2-methyl-4-phenylbutyl)benzamide and linear aliphatic amines e.g., N-(5-phenylpentyl)benzamide from Ni/Co-catalyzed regio- and site-selective hydroalkylations of alkenyl amines e.g., N-(prop-2-en-1-yl)benzamide with alkyl halides RX (R = butan-2-yl, Bn, 2-phenylethyl, 2-(1,3-dioxolan-2-yl)ethyl, etc.; X = I, Br) is developed. This catalytic protocol features the reliable prediction and control of the coupling position of alkylation to provide orthogonal access to α-branched, β-branched and linear alkyl amines from identical starting materials. This platform unlocks orthogonal reactivity and selectivity of nickel hydride and cobalt hydride chem. to catalytically repurpose three types of alkyl amines under mild conditions.

Angewandte Chemie, International Edition published new progress about Aliphatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Application In Synthesis of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wu, Yingtao; Li, Mingrui; Sun, Jiaqiong; Zheng, Guangfan; Zhang, Qian published the artcile< Synthesis of Axially Chiral Aldehydes by N-Heterocyclic-Carbene-Catalyzed Desymmetrization Followed by Kinetic Resolution>, Quality Control of 627-27-0, the main research area is axially chiral aldehyde preparation; biaryl dialdehyde atroposelective esterification desymmetrizing kinetic resolution NHC catalyzed; Axially Chiral Aldehydes; Desymmetrization; Esterification; Kinetic Resolution; N-Heterocyclic Carbenes.

Herein an NHC-catalyzed atroposelective esterification of biaryl dialdehydes as a general and practical strategy for the construction of axially chiral aldehydes I [Ar = Ph, 1-naphthyl, 9-phenanthryl, etc.; R1 = Et, CH2CF3, cyclopropyl, etc.] was described. Mechanistic studies indicated that coupling proceeds through a novel combination of NHC-catalyzed desymmetrization of the dialdehydes and kinetic resolution This protocol featured excellent enantioselectivity, mild conditions, good functional-group tolerance and applicability to late-stage functionalization and provided a modular platform for the synthesis of axially chiral aldehydes and their derivatives

Angewandte Chemie, International Edition published new progress about Aldehydes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Quality Control of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Tan; Miao, Kai; Zhao, Zhigang; Li, Yuqing; Wang, Huiyuan; Watanabe, Atsushi; Teramae, Norio; Wang, Kaige published the artcile< Understanding cellulose pyrolysis under hydrogen atmosphere>, Electric Literature of 627-27-0, the main research area is cellulose pyrolysis hydropyrolysis mechanism.

The product distributions of cellulose pyrolysis under different pressures, temperatures, and atmospheres were investigated using a high-pressure micropyrolyzer to clarify the pyrolysis reaction mechanism of cellulose decomposition with hydrogen. EGA-MS results shows that the increase in hydrogen pressure prolonged the second stage of cellulose pyrolysis, which was dominated by decarboxylation. Pyrolysis products of cellulose under helium mainly included levoglucosan, furfural, and acids, while cellulose hydropyrolysis mainly produced C5-C7 ketones, besides small amount of alcs., aromatics and aliphatic hydrocarbons, and even small amount of phenolics. Carbon yield of ketones was as high as 27.2% from cellulose hydropyrolysis under 2.5 MPa hydrogen and 500°. The yield of liquid products and non-condensable hydrocarbons increased with elevated hydrogen pressure. The formation mechanisms of aromatics, phenolics, aliphatic hydrocarbons, aldehydes, ketones, and alcs. under hydrogen atm. were discussed. Acetaldehyde was produced by acids through a HDO reaction. C5-C7 chain ketones and cyclic ketones were generated by furfural through HDO and hydrocracking reactions. The Diels-Alder reaction to generate aromatics was enhanced by increasing pyrolysis temperature under hydrogen atm. The reaction network of cellulose hydropyrolysis was also proposed.

Energy Conversion and Management published new progress about Chars. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Electric Literature of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jia, Hao; Haering, Andreas P.; Berger, Florian; Zhang, Li; Ritter, Tobias published the artcile< Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3+, CF3• and CF3- Reactivity>, Reference of 627-27-0, the main research area is trifluoromethyl thianthrenium triflate preparation application trifluoromethylation.

Here, the synthesis and application of trifluoromethyl thianthrenium triflate (TT-CF3+OTf-) as a novel trifluoromethylating reagent, which was conveniently accessible in a single step from thianthrene and triflic anhydride was reported. The use of TT-CF3+OTf- in electrophilic, radical, and nucleophilic trifluoromethylation reactions was demonstrated.

Journal of the American Chemical Society published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Reference of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts