Category: 492-62-6

Abraham, Raymond J.; Cooper, M. Ashley; Reid, Matthew published the artcile< The use of MM/QM calculations of 13C chemical shifts in the conformational analysis of some monosaccharides and sucrose>, Formula: C6H12O6, the main research area is MM QM conformational monosaccharide sucrose crystal structure.

The 13C NMR chem. shifts of some common pyranose monosaccharides in D2O solution were predicted using a combined mol. mechanics (Pcmod 9.1/MMFF94) and ab initio (GIAO (B3LYP/DFT, 6-31G(d))) model. This method has been successfully used for a range of organic mols. in CDCl3 solution but has not previously been used for aqueous solutions The method gave such good agreement with experiment that the populations of the conformers at C6 of the monosaccharides could be obtained. This has been attempted previously by various methods with diverse results. In all the compounds studied the α and β anomers have similar populations. In glucose the populations of the GG and GT conformers are ca equal with TG a minor component, in galactose GT has the largest population and GG the smallest, in mannose GG is preferred with TG a minor component and in talose GT and TG are favored with GG a minor constituent. The results are in general agreement with previous work. To our knowledge this is the first time that 13C shifts have been used to determine sugar conformations in solution The conformation of sucrose in D2O solution was examined by both 1H and 13C NMR. The complete anal. of the 1H NMR spectrum has been achieved and provides information on the preferred conformations of the CH2OH fragments at G6 (GG) and F6 (GG, GT). Calculations of the 13C shifts confirm these results and show also that the conformation at F1 is mainly GG plus TG. The sucrose conformational profile in solution includes the crystal structure together with the above conformations at F1 and F6.

New Journal of Chemistry published new progress about Ab initio methods. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xu, Xiaotong; Zhang, Hanmin; Gao, Tianyu; Wang, Yuezhu; Teng, Jiaheng; Lu, Mengyang published the artcile< Customized thin and loose cake layer to mitigate membrane fouling in an electro-assisted anaerobic forward osmosis membrane bioreactor (AnOMEBR)>, Quality Control of 492-62-6, the main research area is electro assisted anaerobic forward osmosis membrane bioreactor wastewater treatment; customized thin loose cake layer mitigation membrane fouling; AnOMEBR; Electro-assisted; Electrostatic repulsion; Membrane fouling alleviation; Membrane surface charge.

An anaerobic forward osmosis (FO) membrane bioreactor (AnOMBR) is a potential wastewater treatment technol. with low energy consumption and high effluent quality; however, membrane fouling remains a considerable problem which causes water flux dwindling and shortened membrane lifetime. An electro-assisted, anaerobic forward osmosis membrane bioreactor (AnOMEBR) was developed to treat wastewater and mitigate membrane fouling, where the conductive FO membrane was used as the separation unit and cathode. Formation, development, and alleviation of membrane fouling in AnOMEBR were assessed. Results showed the soluble microbial products content and protein/polysaccharide (PN/PS) value in AnOMEBR were 26 and 15% lower than that in AnOMBR, resp. The sludge mixture absolute zeta value in AnOMEBR was 1.2 times that of AnOMBR. Increased interaction between the membrane surface and neg. charged foulants could inhibit foulant adsorption on the membrane surface in the initial membrane fouling stage. The strong interaction among foulants further affected the composition, structure, and thickness of the FO membrane surface cake layer. AnOMEBR with a shorter hydraulic retention time, higher organic loading rate, and a lower osmotic pressure difference, could still obtain a lower flux decline rate (0.063 LMH/h), 35.7% lower than AnOMBR. The AnOMEBR wastewater treatment capacity was nearly 1.5 times that of AnOMBR. Results provided an efficient strategy to mitigate membrane fouling and improve wastewater treatment capacity.

Science of the Total Environment published new progress about Biopolymers Role: OCU (Occurrence, Unclassified), RCT (Reactant), OCCU (Occurrence), RACT (Reactant or Reagent) (soluble microbial products and loose- and tightly-bound). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Quality Control of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Malerz, Sebastian; Mudryk, Karen; Tomanik, Lukas; Stemer, Dominik; Hergenhahn, Uwe; Buttersack, Tillmann; Trinter, Florian; Seidel, Robert; Quevedo, Wilson; Goy, Claudia; Wilkinson, Iain; Thuermer, Stephan; Slavicek, Petr; Winter, Bernd published the artcile< Following in Emil Fischer's Footsteps: A Site-Selective Probe of Glucose Acid-Base Chemistry>, Reference of 492-62-6, the main research area is site selective probe glucose acid base chem.

Liquid-jet photoelectron spectroscopy was applied to determine the first acid dissociation constant (pKa) of aqueous-phase glucose while simultaneously identifying the spectroscopic signature of the resp. deprotonation site. Valence spectra from solutions at pH values below and above the first pKa reveal a change in glucose’s lowest ionization energy upon the deprotonation of neutral glucose and the subsequent emergence of its anionic counterpart. Site-specific insights into the solution-pH-dependent mol. structure changes are also shown to be accessible via C 1s photoelectron spectroscopy. The spectra reveal a considerably lower C 1s binding energy of the carbon site associated with the deprotonated hydroxyl group. The occurrence of photoelectron spectral fingerprints of cyclic and linear glucose prior to and upon deprotonation are also discussed. The exptl. data are interpreted with the aid of electronic structure calculations Our findings highlight the potential of liquid-jet photoelectron spectroscopy to act as a site-selective probe of the mol. structures that underpin the acid-base chem. of polyprotic systems with relevance to environmental chem. and biochem.

Journal of Physical Chemistry A published new progress about Acidity (pKa). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Reference of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Matsuo, Koichi; Gekko, Kunihiko published the artcile< Vacuum Ultraviolet Electronic Circular Dichroism Study of D-Glucose in Aqueous Solution>, Application In Synthesis of 492-62-6, the main research area is glucose aqueous solution vacuum UV CD model.

Vacuum UV (VUV) electronic CD (ECD) spectra of D-glucose, α-D-glucopyranose, and β-D-glucopyranose were measured in aqueous solution down to 163 nm using a synchrotron radiation VUV-ECD spectrophotometer and theor. analyzed using mol. dynamics (MD) simulations with explicit water mols. and using time-dependent d. functional theory (TDDFT). The theor. calculated spectra reproduced the exptl. observed spectra well, revealing that VUV-ECD exhibited unique spectra depending on the α-anomer and β-anomer configurations of the hydroxyl group at C-1 and the three gauche (G) and trans (T) rotamer conformations (GT, GG, and TG) of the hydroxymethyl group at C-5. These unique spectra could be ascribed to differences in the patterns of intramol. hydrogen bonds around the hydroxymethyl group at C-5 for the three rotamers and around the hydroxyl group at C-1 for the two anomers. The strengths of these intramol. interactions increased as the degree of hydration around the corresponding chromophores decreased, suggesting that hydration is a key factor for stabilizing rotamer and anomer structures. The rotamerization and anomerization mechanisms are further discussed in terms of differences in the intramol. interactions and the degree of hydration among the rotamer and anomer structures. The findings demonstrate that VUV-ECD spectroscopy is a useful tool for characterizing the equilibrium structures of monosaccharides.

Journal of Physical Chemistry A published new progress about Circular dichroism. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Application In Synthesis of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qiao, Wanjin; Qiao, Yu; Liu, Fulu; Zhang, Yating; Li, Ran; Wu, Zhenzhou; Xu, Haijin; Saris, Per Erik Joakim; Qiao, Mingqiang published the artcile< Engineering Lactococcus lactis as a multi-stress tolerant biosynthetic chassis by deleting the prophage-related fragment>, Electric Literature of 492-62-6, the main research area is proteomics rpsN rplR lysozyme carbohydrate Lactococcus; Genome editing; Lactococcus lactis; Multi-stress tolerance; Nisin immunity; Nisin yield; Prophage-related fragment; TMT quantitative proteomics.

In bioengineering, growth of microorganisms is limited because of environmental and industrial stresses during fermentation This study aimed to construct a nisin-producing chassis Lactococcus lactis strain with genome-streamlined, low metabolic burden, and multi-stress tolerance characteristics. The Cre-loxP recombination system was applied to reduce the genome and obtain the target chassis strain. A prophage-related fragment (PRF; 19,739 bp) in the L. lactis N8 genome was deleted, and the mutant strain L. lactis N8-1 was chosen for multi-stress tolerance studies. Nisin immunity of L. lactis N8-1 was increased to 6500 IU/mL, which was 44.44% higher than that of the wild-type L. lactis N8 (4500 IU/mL). The survival rates of L. lactis N8-1 treated with lysozyme for 2 h and lactic acid for 1 h were 1000- and 10,000-fold higher than that of the wild-type strain, resp. At 39°C, the L. lactis N8-1 could still maintain its growth, whereas the growth of the wild-type strain dramatically dropped. SEM showed that the cell wall integrity of L. lactis N8-1 was well maintained after lysozyme treatment. Tandem mass tags labeled quant. proteomics revealed that 33 and 9 proteins were significantly upregulated and downregulated, resp., in L. lactis N8-1. These differential proteins were involved in carbohydrate and energy transport/metabolism, biosynthesis of cell wall and cell surface proteins. PRF deletion was proven to be an efficient strategy to achieve multi-stress tolerance and nisin immunity in L. lactis, thereby providing a new perspective for industrially obtaining engineered strains with multi-stress tolerance and expanding the application of lactic acid bacteria in biotechnol. and synthetic biol. Besides, the importance of PRF, which can confer vital phenotypes to bacteria, was established.

Microbial Cell Factories published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Electric Literature of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Abdullayev, Yusif; Ahmadov, Orkhan; Valadova, Gunay; Karimli, Ayan; Autschbach, Jochen published the artcile< Unveiling the catalytic effects of Bronsted acidic ionic liquid on quantitative α-glucose conversion to 5-HMF: Experimental and computational studies>, Synthetic Route of 492-62-6, the main research area is glucose Bronsted acidic ionic liquid dehydration mechanism.

Effective biomass conversion to 5-HMF(5-hydroxymethylfurfural) is still a challenge and needs to be improved because of the 5-HMF importance as building blocks for valuable monomers and fuel precursors. We suggest for the first time utilization of low-cost metal-free Bronsted acidic Ionic liquid (IL) N,N-Diethyl-1,4-phenylenediamine hydrogen sulfate, [DPhDA]HSO4 as a catalyst for the α-glucose dehydration to 5-HMF. Quant. α-glucose conversion is achieved via optimizing the reaction condition: 91.4% 5-HMF yield with 30 mol% [DPhDA]HSO4 in the presence of DMSO as a solvent at 160°C in 30 min (TOF 6.1 h-1). 3-fold increase in reaction time leads to higher (94%) 5-HMF yield at 160°C with lower TOF 1.6 h-1. The IL surprising catalytic performance is scrutinized with its amphiprotic nature (availability of basic and acidic spots in its structure (Fig. 1)). Further computational mechanistic studies revealed the function of the catalytic sites in the α-glucose dehydration. We calculated five-membered ring formation and water extrusion in one concerted transition state (TS2A, ΔG‡ = 38.8 kcal/mol) following the α-glucose ring-opening (TS1, ΔG‡ = 20.4 kcal/mol). Further four steps (sp3-s, C-H bond cleavages (TS3, TS6) and dehydroxylation (TS4A, TS5)) are quite straightforward to reach the product (5-HMF).

Renewable Energy published new progress about Dehydration reaction. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Synthetic Route of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shishmarev, Dmitry; Quiquempoix, Lucas; Fontenelle, Clement Q.; Linclau, Bruno; Kuchel, Philip W. published the artcile< Anomerization of Fluorinated Sugars by Mutarotase Studied Using 19F NMR Two-Dimensional Exchange Spectroscopy>, Reference of 492-62-6, the main research area is anomerization fluorinated monosaccharide mutarotase glucose enzyme mol structure NMR.

Five 19F-substituted glucose analogs were used to probe the activity and mechanism of the enzyme mutarotase by using magnetization-exchange NMR spectroscopy. The sugars (2-fluoro-2-deoxy-d-glucose, FDG2; 3-fluoro-3-deoxy-d-glucose, FDG3; 4-fluoro-4-deoxy-d-glucose, FDG4; 2,3-difluoro-2,3-dideoxy-d-glucose, FDG23; and 2,2,3,3-tetrafluoro-2,3-dideoxy-d-glucose (2,3-dideoxy-2,2,3,3-tetrafluoro-d-erythro-hexopyranose), FDG2233) showed sep. 19F NMR spectroscopic resonances from their resp. α- and β-anomers, thus allowing two-dimensional exchange spectroscopy measurements of the anomeric interconversion at equilibrium, on the time scale of a few seconds. Mutarotase catalyzed the rapid exchange between the anomers of FDG4, but not the other four sugars. This finding, combined with previous work identifying the mechanism of the anomerization by mutarotase, suggests that the rotation around the C1-C2 bond of the pyranose ring is the rate-limiting reaction step. In addition to D-glucose itself, it was shown that all other fluorinated sugars inhibited the FDG4 anomerization, with the tetra-fluorinated FDG2233 being the most potent inhibitor. Inhibition of mutarotase by F-sugars paves the way for the development of novel fluorinated compounds that are able to affect the activity of this enzyme in vitro and in vivo.

Australian Journal of Chemistry published new progress about Anomerization. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Reference of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Iles, Bruno; Ribeiro de Sa Guimaraes Noleto, Isabela; Dourado, Flaviane Franca; de Oliveira Silva Ribeiro, Fabio; de Araujo, Alyne Rodrigues; de Oliveira, Taiane Maria; Souza, Jessica Maria Teles; Barros, Ayslan Batista; Sousa, Gabrielle Costa; de Jesus Oliveira, Antonia Carla; da Silva Martins, Conceicao; de Oliveira Viana Veras, Mariana; de Carvalho Leitao, Renata Ferreira; de Souza de Almeida Leite, Jose Roberto; da Silva, Durcilene Alves; Medeiros, Jand Venes Rolim published the artcile< Alendronate sodium-polymeric nanoparticles display low toxicity in gastric mucosal of rats and Ofcol II cells>, Synthetic Route of 492-62-6, the main research area is alendronate sodium polymeric nanoparticle gastric toxicity osteotoxicity; Alendronate; Cashew gum; Gastric lesion; Polymeric nanoparticle; Red Angico gum.

The use of bisphosphonates constitutes the gold-standard therapy for the control and treatment of bone diseases. However, its long-term use may lead to gastric problems, which limits the treatment. Thus, this study aimed to formulate a nanostructured system with biodegradable polymers for the controlled release of alendronate sodium. The nanoparticles were characterized, and its gastric toxicity was investigated in rats. The synthesis process proved to be effective for encapsulating alendronate sodium, exhibiting nanoparticles with an average size of 51.02 nm and 98.5% of alendronate sodium incorporation. The release tests demonstrated a controlled release of the drug in 420 min, while the morphol. analyzes showed spherical shapes and no apparent roughness. The biol. tests demonstrated that the alendronate sodium nanoformulation reversed the gastric lesions, maintaining the normal levels of malondialdehyde and myeloperoxidase. Also, the encapsulated alendronate sodium showed no toxicity in murine osteoblastic cells, even at high concentrations

NanoImpact published new progress about Anacardium occidentale. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Synthetic Route of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ruschhaupt, Peter; Varzi, Alberto; Passerini, Stefano published the artcile< Natural Polymers as Green Binders for High-Loading Supercapacitor Electrodes>, Product Details of C6H12O6, the main research area is natural polymer green binder high loading supercapacitor electrode; binders; carbohydrates; flexible electrodes; high mass loading; supercapacitors.

The state-of-the-art aqueous binder for supercapacitors is CM-cellulose (CMC). However, it limits the mass loading of the coatings owing to shrinkage upon drying. In this work, natural polymers, i.e., guar gum (GG), wheat starch (WS), and potato starch (PS), were studied as alternatives. The flexibility and adhesion of the resulting coatings and electrochem. performance was tested. The combination of 75:25 (weight/weight) ratio PS/GG showed a promising performance. Electrodes were characterized by SEM, thermal, adhesion, and bending tests. Their electrochem. properties were determined by cyclic voltammetry, electrochem. impedance spectroscopy, and cycling experiments The PS/GG mixture conformed well to criteria for industrial production, enabling mass loadings higher than CMC (7.0 mg cm-2) while granting the same specific capacitance (26 F g-1) and power performance (20 F g-1 at 10 A g-1). Including the mass of the current collector, this represents a +45% increase in specific energy at the electrode level.

ChemSusChem published new progress about Binders. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ruschhaupt, Peter; Varzi, Alberto; Passerini, Stefano published the artcile< Natural Polymers as Green Binders for High-Loading Supercapacitor Electrodes>, Product Details of C6H12O6, the main research area is natural polymer green binder high loading supercapacitor electrode; binders; carbohydrates; flexible electrodes; high mass loading; supercapacitors.

The state-of-the-art aqueous binder for supercapacitors is CM-cellulose (CMC). However, it limits the mass loading of the coatings owing to shrinkage upon drying. In this work, natural polymers, i.e., guar gum (GG), wheat starch (WS), and potato starch (PS), were studied as alternatives. The flexibility and adhesion of the resulting coatings and electrochem. performance was tested. The combination of 75:25 (weight/weight) ratio PS/GG showed a promising performance. Electrodes were characterized by SEM, thermal, adhesion, and bending tests. Their electrochem. properties were determined by cyclic voltammetry, electrochem. impedance spectroscopy, and cycling experiments The PS/GG mixture conformed well to criteria for industrial production, enabling mass loadings higher than CMC (7.0 mg cm-2) while granting the same specific capacitance (26 F g-1) and power performance (20 F g-1 at 10 A g-1). Including the mass of the current collector, this represents a +45% increase in specific energy at the electrode level.

ChemSusChem published new progress about Binders. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts