Category: 107-54-0

Islam, Sk. Safikul published the artcileGreen Synthesized AgNPs Embedded in COF: An Efficient Catalyst for the Synthesis of 2-Oxazolidinones and α-Alkylidene Cyclic Carbonates via CO2 Fixation, Application of 3,5-Dimethylhex-1-yn-3-ol, the main research area is porous covalent organic framework silver nanocatalyst preparation; terminal propargyl amine carboxylative cyclization; propargyl alc carboxylative cyclization; aryl oxazolidinone green preparation; cyclic carbonate green preparation.

The synthesis of silver nanoparticles (AgNPs) by an eco-friendly method and incorporation of the particles into a covalent organic framework obtained a sustainable heterogeneous catalyst, AgN@COF was demonstrated. The catalyst was characterized in detail by FT-IR,UV-Vis. spectroscopy, FE-SEM, TEM, EDAX, XPS, PXRD, ICP-AES, TG-DTA and N2 absorption-desorption studies. The synthesized catalyst was able to fix CO2 to terminal propargylic amine and propargylic alc. for the production of 2-oxazolidinones and α-alkylidene cyclic carbonates, resp., through two different catalytic pathways. In both catalytic protocols, one atm. carbon dioxide was used. Production of α-alkylidene cyclic carbonates occurred at room temperature and solvent-free condition, and 2-oxazolidinones were obtained under mild reaction conditions. Moreover, the catalyst was recyclable and reusable. Its catalytic efficacy was preserved even after the use of six consecutive catalytic cycles.

ChemNanoMat published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Application of 3,5-Dimethylhex-1-yn-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhou, Yulu published the artcilePhotocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes, HPLC of Formula: 107-54-0, the main research area is cyclopentene indene preparation regioselective; alkyne sodium sulfinate photocatalytic Sulfonylcarbocyclization; 5-endo-trig cyclization; C−H functionalization; alkyne; photocatalysis; radical.

Herein, a traceless directing group strategy was designed to reverse the regioselectivity of radical addition which enabled an unprecedented photocatalytic sulfonylcarbocyclization of terminal alkynes by forming C-C bond on inert C(sp3)-H bond. It offered a facile access to decorated cyclopentenes and indenes under mild conditions. The resultant products could be converted into a set of valuable mol. scaffolds, including a key intermediate of AM-6226. Mechanistic experiments suggested a radical cascade pathway comprising a Markovnikov-type sulfonylation, 1,5-hydrogen atom transfer, 5-endo-trig cyclization, and β-elimination. This study lays further groundwork for the use of anti-Baldwin 5-endo-trig radical cyclization in rapidly assembling five-membered carbocycles.

Angewandte Chemie, International Edition published new progress about Cyclization (sulfonylcarbocyclization). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, HPLC of Formula: 107-54-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Karlinskii, Bogdan Ya. published the artcileSynthesis of 2-Azidomethyl-5-ethynylfuran: A New Bio-Derived Self-Clickable Building Block, Computed Properties of 107-54-0, the main research area is azidomethylfurancarboxaldehyde preparation azide alkyne cycloaddition; triazolylmethylfurancarboxaldehyde preparation; azidomethylethynylfuran preparation polymerization copper catalyzed azide alkyne cycloaddition; biomass derived azide containing alkyne preparation polymerization; safety toxicity sodium azide.

Furanylmethyl azide I was prepared in three steps from D-fructose or cellulose; copper-catalyzed azide-alkyne cycloaddition of I with terminal alkynes and diynes yielded triazolylmethylfurancarboxaldehydes such as II [R = Me2C(OH), Ph, BuCH2, BuCH2CCCH2, MeO2C, NC(CH2)3, HO(CH2)4, BocNHCH2, HOCH2, 3-quinolinyl, MeOCH2, t-Bu, cyclopropyl, i-PrCH2CMe(OH), t-BuCMe(OH)]. 2-Azidomethyl-5-ethynylfuran III was prepared as a monomer; in the presence of CuBr and pentamethyldiethylenetriamine, it underwent polymerization to form oligomer with MN = 4100 g/mol. Sodium azide is toxic and should be handled with care.

Synthesis published new progress about Azide-alkyne 1,3-dipolar cycloaddition reaction. 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Computed Properties of 107-54-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Roberts, Dean D. published the artcileRegioselective Synthesis of Multifunctional Allylic Amines; Access to Ambiphilic Aziridine Scaffolds, SDS of cas: 107-54-0, the main research area is allylic amine ambiphilic aziridine preparation regioselective; propargylic amine dimethylphenylsilane hydrosilylation platinum chloride XantPhos catalyst.

A highly regioselective hydrosilylation of propargylic amines has been described here for the first time. The reaction utilizes a PtCl2/XantPhos catalyst system to deliver hydrosilanes across the alkyne to afford multifunctional allylic amines in high yields. The reaction is tolerant to a wide variety of functional groups and provides high value intermediates with two distinct functional handles. The synthetic applicability of the reaction has been shown through the synthesis of diverse ambiphilic aziridines.

Organic Letters published new progress about Amines, propargyl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, SDS of cas: 107-54-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Yu-Lan published the artcileFour-component defluorinative reaction of allylic fluorides, amidines, and Cs2CO3 under transition-metal-free conditions, Name: 3,5-Dimethylhex-1-yn-3-ol, the main research area is hydroxy iodoperfluorobutene amidine cesium carbonate tandem defluorinative heterocyclization; pyrimidinylmethyl iminomethyl carbamate preparation green chem.

An unprecedented four-component defluorinative reaction of allylic fluorides, amidines, and Cs2CO3 for the convenient synthesis of valuable pyrimidine-containing amidino carbamates under transition-metal-free conditions was reported. The synthetic linchpin for realizing the multi-bonding tandem protocol relied on the directed function of the α-positioned hydroxyl group and the activating effect of the perfluoroalkyl substituent in allylic fluorides. Moreover, cesium carbonate served as a green carbonyl equivalent for formal CO capture. Mechanistic studies revealed that the reaction proceeded via a possible cyclic carbonate intermediate.

Green Chemistry published new progress about Amidines Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Name: 3,5-Dimethylhex-1-yn-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kumar, Shreemoyee published the artcileRu(II)-catalyzed allenylation and sequential annulation of N-tosylbenzamides with propargyl alcohols, Recommanded Product: 3,5-Dimethylhex-1-yn-3-ol, the main research area is allenylamide isoquinolone preparation; tosylbenzamide propargyl alc allenylation sequential annulation ruthenium catalyst.

Here Ru(II)-catalyzed C(sp2)-H allenylation of N-tosylbenzamides to access multi-substituted allenylamides has been reported. Furthermore, the allenylamides were converted to the corresponding isoquinolone derivatives via base mediated annulation. The current protocol features low catalyst loading, mild reaction conditions, high functional group compatibility and desired scalability. The unique functionality of the afforded allenes allowed further transformations to expand the practicality of the protocol.

Chemical Communications (Cambridge, United Kingdom) published new progress about Allenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Recommanded Product: 3,5-Dimethylhex-1-yn-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Luo, Yi published the artcileFormation of diversified spiro-[imidazole-indene] derivatives from 2H-imidazoles: based on versatile propargyl alcohols, COA of Formula: C8H14O, the main research area is phenylimidazole aryl propargyl alc rhodium catalyst regioselective tandem spirocyclization; aryl spiro imidazole indene preparation.

Rh(III)-catalyzed efficient cascade annulation for the regioselective construction of various spiro[imidazole-indene] derivatives were reported by utilizing versatile propargyl alcs. as coupling partners. The type of propargyl alc. played a key role in tuning the combination state and controlling formation of different products.

Organic Chemistry Frontiers published new progress about Alkenylation. 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, COA of Formula: C8H14O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cui, Hui-Ya published the artcileEngineering noble-metal-free metal-organic framework composite catalyst for efficient CO2 conversion under ambient conditions, COA of Formula: C8H14O, the main research area is copper bromide zeolite catalyst CO2 propargylamine propargyl alc cycloaddition.

The cyclization of propargylic alcs. and propargylic amines with CO2 are of great significance since the generated O/N-containing cyclic skeletons are extensively employed in pharmaceutical chem. and industrial production However, most of the reported catalysts only effectively catalyze propargylic alcs. or propargylic amines with CO2, and often involve noble-metal catalysts, high temperature and CO2 pressure. It is a great challenge that non-noble-metal catalysts catalyzed both propargylic alcs. and propargylic amines with CO2 under ambient conditions. Herein, CuBr@NH2-MIL-101 was successfully synthesized by loading CuBr nanoparticles into zeolite-type NH2-MIL-101 via simple thermal conversion method, and it displayed highly selective CO2 uptake properties. Importantly, CuBr@NH2-MIL-101 featured high catalytic activity for carboxylative cyclization of both propargylic alcs. and propargylic amines with CO2 under ambient conditions (25°C, 0.1 MPa CO2), resp. Moreover, CuBr@NH2-MIL-101 can be recycled at least three times without significant decline in catalytic activity. The combination explorations of NMR, FTIR and 13C isotope labeling experiments clearly illustrate the reaction process and mechanism. The d. functional theory (DFT) calculations uncover that CuBr and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) can synergistically activate substrates, and the proton-demetalation step with the highest energy barrier was the rate-determining step in two catalytic systems. To our knowledge, it is the first report of noble-metal-free catalyst that can simultaneously catalyze CO2 conversion with propargylic alcs. and propargylic amines under room temperature and atm. CO2 pressure.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Amines, propargyl Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, COA of Formula: C8H14O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ji, Xiaoliang published the artcilePalladium-Catalyzed Cross Haloalkynylation of Haloalkynes, Quality Control of 107-54-0, the main research area is dihaloalkenyne preparation regioselective chemoselective diastereoselective; haloalkynol haloalkyne cross haloalkynylation palladium catalyst.

A robust Pd-catalyzed haloalkynylation of haloalkynes for the synthesis of dihaloalkenyne derivatives R1R2C(OH)C≡CC(R3)=C(R4)R5 [R1 = Me, Et, n-Bu, i-Bu, 3-ClC6H4CH2; R2 = Me, Et, n-Bu, i-Bu; R3 = Br, Cl; R4 = Br, Cl; R5 = hexyl, Ph, 4-MeC6H4, etc.; R1R2 = (CH2)4, (CH2)5, (CH2)7, etc.] was developed. This cross-haloalkynylation reaction proceeded in a highly chemo- and regioselective manner under mild conditions in the presence of two slightly structurally different haloalkynes and showed strong functional group tolerance under ligand- and base-free conditions.

Organic Letters published new progress about Alkynyl alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Quality Control of 107-54-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts