Category: 10030-85-0

Sulfated polysaccharides with antioxidant and anticoagulant activity from the sea cucumber Holothuria fuscogliva was written by Li, Rongfeng;Yu, Huahua;Yue, Yang;Liu, Song;Xing, Rong’e;Chen, Xiaolin;Li, Pengcheng. And the article was included in Chinese Journal of Oceanology and Limnology in 2017.Recommanded Product: 10030-85-0 This article mentions the following:

Sea cucumber is a traditional nutritional food and medicinal resource with many bioactive components in China. Holothuria fuscogliva is a big sea cucumber with a rich of bioactive polysaccharides. To investigate the bioactivities of the polysaccharides from sea cucumber H. fuscogliva, we prepared the sulfated polysaccharides (HfP) from sea cucumber H. fuscogliva using a protease hydrolysis method. Antioxidant activities of HfP were investigated, including hydroxyl radical scavenging activity and superoxide radical scavenging activity. And, the anticoagulant activities of HfP were studied, including the activated partial thromboplastin time (APTT), prothrombin time (PT) and thrombin time (TT). The average mol. weight was 1 867.1 Da, with a sulfate content of 20.7%. In addition, the molar ratio of monosaccharide composition of HfP was Man: Rha: Glc A: Glc: Gal: Xyl: Fuc=0.083 6: 0.437: 0.134: 0: 1.182: 0.748: 1. It had a strong antioxidant activity, the hydroxyl and superoxide radical scavenging activity EC 50 of HfP was 3.74 and 0.037 mg/mL, resp. It also showed a good anticoagulant activity in our study. The APTT of HfP was much higher than that of heparin sodium, and the PT and TT of HfP was close to that of heparin sodium at a low concentration Therefore, HfP shows a good antioxidant and anticoagulant activity and it may become a potential candidate of the natural antioxidant and anticoagulant and will have a good application future in health product or medicine industry. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Recommanded Product: 10030-85-0).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 10030-85-0

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Halomonas montanilacus sp. nov., isolated from hypersaline Lake Pengyanco on the Tibetan Plateau was written by Lu, Huibin;Xing, Peng;Zhai, Lei;Li, Huabing;Wu, Qinglong. And the article was included in International Journal of Systematic and Evolutionary Microbiology in 2020.Product Details of 10030-85-0 This article mentions the following:

A Gram-stain-neg., catalase- and oxidase-pos., aerobic, rod-shaped, motile strain (PYC7WT) was isolated from Lake Pengyanco on the Tibetan Plateau. Comparisons based on 16S rRNA gene sequences showed that strain PYC7WT belongs to the genus Halomonas, with Halomonas malpeensis YU-PRIM-29T and Halomonas johnsoniae T68687T as its closest neighbors (96.8 and 96.6% 16S rRNA gene sequence similarity, resp.), and only 93.1% 16S rRNA gene sequence similarity to Halomonas elongata ATCC 33173T. The predominant respiratory quinone of strain PYC7WT is Q-9, with Q-8 as a minor component. The major fatty acids are C18:1 ω6c and / or C18:1 ω7c, C16:0, C16:1 ω6c and/or C16:1 ω7c, and C12:0 3OH. The polar lipids of strain PYC7WT include phosphatidylethanolamine, phosphatidylglycerol, diphosphatidylglycerol, phosphatidylinositol and two unidentified phospholipids. Genome sequencing revealed a genome size of 4.79 Mbp and a G+C content of 62.9 mol%. DNA-DNA hybridization values of strain PYC7WT showed 45, 30 and 38% relatedness with Halomonas johnsoniae DSM 21197T, Halomonas hamiltonii DSM 21196T and Halomonas stevensii DSM 21198T, resp. Combining phenotypic, biochem., genotypic and DNA-DNA hybridization data, we propose that strain PYC7WT represents a novel species within the genus Halomonas and to have the name Halomonas montanilacus sp. nov.; PYC7WT (=CICC 24506T= KCTC 62529T) is the type strain. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Product Details of 10030-85-0).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Product Details of 10030-85-0

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

High cobalt exposure facilitates bioactive exopolysaccharides production with a novel molecular structure in Botryococcus braunii was written by Cheng, Pengfei;Chang, Ting;Wang, Chun;Yao, Changhong;Zhou, Chengxu;Liu, Tianzhong;Wang, Guangce;Yan, Xiaojun;Ruan, Roger. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022.Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate This article mentions the following:

The promising unicellular colonial Botryococcus braunii can secrete large amounts of bioactive exopolysaccharides. Our previous study revealed Botryococcus could tolerate high-concentrations of metallic cobalt, and extracellular hydrocarbons increased simultaneously. However, the characteristics of the extracellular polysaccharides (EPS) closely related to extracellular hydrocarbons is still unclear. This research focuses on the effects of cobalt exposure on the production, structure, and bioactivity of exopolysaccharides from colonial Botryococcus, aiming to provide a theor. clue on the potential contribution of EPS to the cobalt tolerance ability in this alga for cobalt bioremediation from the perspective of structure-bioactivity relationship. The results showed that high cobalt treatment (4.5 mg/L) exerted little influence on the growth of the alga, or the total carbohydrate content obtained, compared to the algae without cobalt treatment. EPSs of B. braunii SAG 30.81, under normal condition (EPS-Co) was mainly composed of glucose, mannose, fucose, galactose, rhamnose, and xylose, but also with the presence of sulfate substitutions, which was unique among the EPSs previously reported in this alga. Cobalt treatment resulted in a remarkable decline of rhamnose, and an increase of ribose and sulfate content, with more esterified uronic acids in the EPS (EPS + Co). EPS + Co, overall, had a larger but more compact and branched, spherical-like EPSs, with more ordered (helix) chains relative to EPS-Co. EPS + Co exhibited stronger antioxidant and antibacterial activity than EPS-Co, which could be attributed to the changed structural characteristics, such as the decrease of Rha, Fuc, and Gal and an increase of sulfate substitutions, uronic acids and Ara, more branched structure, and more ordered conformation. The enhanced antioxidant activity could be contributed to the alga tolerance to cobalt exposure, which was benefitted by cobalt bioremediation. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Safety of (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Identification of L-rhamnose in aspenwood was written by Jones, J. K. N.;Schoettler, J. R.. And the article was included in Tappi in 1952.Category: alcohols-buliding-blocks This article mentions the following:

Aspenwood (I) meal was hydrolyzed at 90° with N H₂SO₄; the hydrolyzate, when examined chromatographically showed the presence of xylose, galactose, and arabinose, and possibly glucose, mannose, and glucurone. L-Rhamnose (II) was present in very small amounts (< 1%), and was isolated as the cryst, hydrate, [α]_D 9° (H₂O), which was then converted into the characteristic benzoylhydrazone, m. 188°. Presumably this is the first time that II has been isolated from the hydrolyzate of I. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0Category: alcohols-buliding-blocks).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

An Improved Synthesis of 4-O-Benzoyl-2,2-difluorooleandrose from L-Rhamnose. Factors Determining the Synthesis of 2,2-Difluoro-Carbohydrates from 2-Uloses was written by Barrena, M. Isabel;Matheu, M. Isabel;Castillon, Sergio. And the article was included in Journal of Organic Chemistry in 1998.COA of Formula: C6H14O6 This article mentions the following:

4-O-Benzoyl-2,2-difluorooleandrose I has been synthesized from L-rhamnose via DAST difluorination of ulose II followed by chemoselective etherification. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0COA of Formula: C6H14O6).

(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal hydrate (cas: 10030-85-0) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C6H14O6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts