Category: 100-55-0

In 2019,Food Additives & Contaminants, Part A included an article by Gong, Jin; Zheng, Kunming; Yang, Guoqiang; Zhao, Shan; Zhang, Kankan; Hu, Deyu. Name: 3-Pyridinemethanol. The article was titled 《Determination, residue analysis, risk assessment and processing factor of pymetrozine and its metabolites in Chinese kale under field conditions》. The information in the text is summarized as follows:

A simple determination method for pymetrozine and its metabolites in Chinese kale was developed using liquid chromatog. with tandem mass spectrometry. The method had good linearity (R2 > 0.99), accuracy (recoveries of 73.2-94.1%) and precision (relative standard deviation of 2.5-9.8%). Field results showed that half-lives of pymetrozine were 3.0-4.1 d in Chinese kale, and terminal residue concentrations were all below the United States Environmental Protection Agency’s maximum residue limit (250 μg/kg) at harvest. Owing to risk quotient <100%, pymetrozine is unlikely to give rise to vital health concerns to humans following the recommended application guidelines. Moreover, effects of home processing on pymetrozine residues in Chinese kale were monitored. The processing factor values of four processes were between 0.19 and 0.60, which indicated that the used processes could remove pymetrozine residues from Chinese kale, especially pickling after washing process. The data could provide guidance to safe and reasonable use of pymetrozine and help Chinese governments establish a maximum residue limit for pymetrozine in Chinese kale. In addition to this study using 3-Pyridinemethanol, there are many other studies that have used 3-Pyridinemethanol(cas: 100-55-0Name: 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Name: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Park, Kwihwan; Jiang, Jing; Yamada, Tsuyoshi; Sajiki, Hironao published their research in Chemical & Pharmaceutical Bulletin in 2021. The article was titled 《Ruthenium-on-carbon-catalyzed facile solvent-free oxidation of alcohols: efficient progress under solid-solid (liquid)-gas conditions》.Recommanded Product: 3-Pyridinemethanol The article contains the following contents:

A protocol for the ruthenium-on-carbon (Ru/C)-catalyzed solvent-free oxidation of alcs., which proceeds efficiently under solid-solid (liquid)-gas conditions, was developed. Various primary and secondary alcs. were transformed to corresponding aldehydes and ketones in moderate to excellent isolated yields by simply stirring in the presence of 10% Ru/C under air or oxygen conditions. The solvent-free oxidation reactions proceeded efficiently regardless of the solid or liquid state of the substrates and reagents and could be applied to gram-scale synthesis without loss of the reaction efficiency. Furthermore, the catalytic activity of Ru/C was maintained after five reuse cycles. In addition to this study using 3-Pyridinemethanol, there are many other studies that have used 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Narjinari, Himani; Tanwar, Niharika; Kathuria, Lakshay; Jasra, Raksh Vir; Kumar, Akshai published an article in Catalysis Science & Technology. The title of the article was 《Guerbet-type β-alkylation of secondary alcohols catalyzed by chromium chloride and its corresponding NNN pincer complex》.Application of 100-55-0 The author mentioned the following in the article:

The β-alkylation of secondary alcs. had been successfully accomplished using earth abundant, inexpensive and environmentally benign 3d transition metal chromium salt CrCl3 and its corresponding pincer-Cr complex, (Ph2NNN)CrCl3 (0.005 mol%), at 140°C in air under conventional (3 h) and microwave heating conditions (ca. 75 W for 1.5 h) in the presence of NaOtBu (5 mol%) to obtain β-alkylated alcs. R(CH2)2CH(OH)R1 [R = Ph, cyclohexyl, 4-ClC6H4, etc.; R1 = Ph, 4-MeC6H4, 2-thienyl, etc.]. Microwave conditions provided better results (90% yield and 18 000 TON at 12 000 TOh-1) in comparison to conventional heating (84% yield and 16 800 TON at 5600 TOh-1). While CrCl3 (0.005 mol%) afforded 76% yield (15 200 TON at 10 133 TOh-1) of the β-alkylated alcs. under microwave conditions in the presence of 5 mol% NaOtBu, the corresponding pincer-Cr complex (Ph2NNN)CrCl3 (0.005 mol%) resulted in 90% yield (18 000 TON at 12 000 TOh-1) of the β-alkylated alcs. under similar conditions. EPR studies suggest the involvement of chromium(II) active species when either CrCl3 or its corresponding NNN pincer was used. HRMS anal., hot-filtration and mercury-drop test provided conclusive evidence for the homogeneous and well-defined mol. nature of the reaction mixture Apparently, insertion of the α-alkylated ketone into the Cr-H bond was the RDS based on inferences drawn from deuterium labeling studies that demonstrate a KIE of 7.33 and HRMS anal. which provided vital information on the resting-state of the reaction. The experimental part of the paper was very detailed, including the reaction process of 3-Pyridinemethanol(cas: 100-55-0Application of 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Application of 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Selective trimethylsilylation of alcohols and phenols with hexamethyldisilazane catalyzed by LaCoO3 perovskite》 were Mehdipour, Ebrahim; Baharlouei, Ehsan; Zarnegar, Zohre. And the article was published in Iranian Chemical Communication in 2019. Name: 3-Pyridinemethanol The author mentioned the following in the article:

Trimethylsilylation of alcs. and phenols were carried out under solvent-free conditions with hexamethyldisilazane (HMDS) using LaCoO3 perovskite. LaCoO3 as an efficient catalyst accelerated this reaction under milder condition. The advantages of this method are evident regarding, easy separation, low cost and low catalyst loading, lack of pollution, easy work-up, and selective protection of primary and secondary alcs. After reading the article, we found that the author used 3-Pyridinemethanol(cas: 100-55-0Name: 3-Pyridinemethanol)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Name: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《N-Doped Yellow TiO2 Hollow Sphere-Mediated Visible-Light-Driven Efficient Esterification of Alcohol and N-Hydroxyimides to Active Esters》 were Singha, Krishnadipti; Ghosh, Subhash Ch.; Panda, Asit Baran. And the article was published in Chemistry – An Asian Journal in 2019. Safety of 3-Pyridinemethanol The author mentioned the following in the article:

A simple synthetic protocol for N-doped yellow TiO2 (N-TiO2) hollow spheres as an efficient visible-light-active photocatalyst using aqueous titanium peroxocarbonate complex (TPCC) solution as precursor and NH4OH was developed. In the developed strategy, the ammonium ion of TPCC and NH4OH acts as nitrogen source and structure-directing agent. The synthesized N-TiO2 hollow spheres were capable of promoting the synthesis of active esters ArCO2R [Ar = Et, 4-ClC6H4, 2-furyl, etc.; R = 2,5-dioxopyrrolidin-1-yl, 1,3-dioxoisoindolin-2-yl] of N-hydroxyimide and alc. through simultaneous selective oxidation of alc. to aldehyde followed by cross-dehydrogenative coupling (CDC) under ambient conditions upon irradiation of visible light. It was possible to develop a novel and cost-effective one-pot strategy for the synthesis of important esters and amides on gram scale using the developed strategy. The catalytic activity of N-TiO2 hollow spheres was much superior to that of other reported N-TiO2 samples as well as TiO2 with varying morphol. In addition to this study using 3-Pyridinemethanol, there are many other studies that have used 3-Pyridinemethanol(cas: 100-55-0Safety of 3-Pyridinemethanol) was used in this study.

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Safety of 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Gang; Kim, Hyejin; Wang, Pingyuan; Fricke, Doerte R.; Chen, Haiying; Wang, Tianzhi; Shen, Qiang; Zhou, Jia published an article in 2021. The article was titled 《Further lead optimization on Bax activators: Design, synthesis and pharmacological evaluation of 2-fluoro-fluorene derivatives for the treatment of breast cancer》, and you may find the article in European Journal of Medicinal Chemistry.HPLC of Formula: 100-55-0 The information in the text is summarized as follows:

Fluorofluorene I exhibited a good balance between antitumor activity and toxicity, displaying submicromolar activities against a variety of cancer cell lines with 5.8-10.7-fold selectivity of decreased activity to MCF-10A human mammary epithelial cell line. Compound I dose-dependently blocked colony formation of breast cancer cells and prevented the migration and invasion of MDA-MB-231 cells. Mechanism of action studies indicate that I activated Bax, rendering its insertion into mitochondrial membrane, thereby leading to cytochrome c release from the mitochondria into the cytoplasm, subsequently inducing release of apoptotic biomarkers. Further in vivo efficacy studies of I in human breast cancer xenografts arisen from MDA-MB-231 cells demonstrated that this drug candidate significantly suppressed tumor growth, indicating the therapeutic promise of this class of compounds for the treatment of breast cancer as well as the potential for developing F-radiolabeled imaging ligands as anticancer chem. probes. After reading the article, we found that the author used 3-Pyridinemethanol(cas: 100-55-0HPLC of Formula: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. HPLC of Formula: 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of C6H7NOIn 2020 ,《Ruthenium Catalyzed Divergent Alkylation and Olefination of Methyl 1,3,5-Triazines with Alcohols》 was published in European Journal of Organic Chemistry. The article was written by Su, Chengwu; Zeng, Ming; Zhang, Chen; Cui, Dong-Mei. The article contains the following contents:

An efficient ruthenium-catalyzed divergent alkylation and olefination of Me 1,3,5-triazines with alcs. have been developed. The selectivity can be rationally tuned by the judicious choice of ruthenium catalyst, wherein Ru(PPh3)3Cl2 delivers alkylated 1,3,5-triazines and RuCl3 gives olefinated 1,3,5-triazines in up to 98% yield. Following this simple, facile, and high atom economical protocol, a broad range of products was prepared in moderate to good yields and tolerated heterocyclic or benzylic alcs. containing functionalities. The overall transformation operates through dehydrogenation of primary alcs. under the reaction conditions to provide the corresponding aldehydes, which further undergo condensation with Me 1,3,5-triazines. The experimental part of the paper was very detailed, including the reaction process of 3-Pyridinemethanol(cas: 100-55-0Synthetic Route of C6H7NO)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Synthetic Route of C6H7NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kobayashi, Masaki; Yamaguchi, Hiroki; Suzuki, Takeyuki; Obora, Yasushi published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Cross β-alkylation of primary alcohols catalysed by DMF-stabilized iridium nanoparticles》.Recommanded Product: 3-Pyridinemethanol The article contains the following contents:

A simple method for the cross β-alkylation of linear alcs. R(CH2)2OH (R = octyl, cyclohexylmethyl, Ph, 3-benzyl-4-hydroxybutyl, etc.) with benzyl alcs. R1CH2OH (R1 = Ph, cyclopropyl, thiophen-2-yl, etc.) in the presence of DMF-stabilized iridium nanoparticles was developed. The nanoparticles were prepared in one-step and thoroughly characterized. Furthermore, the optimum reaction conditions have a wide substrate scope and excellent product selectivity. In the part of experimental materials, we found many familiar compounds, such as 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 3-Pyridinemethanol)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kiesow, Andreas; Teuscher, Nico; Morawietz, Maria; Eick, Sigrun published their research in Oral health & preventive dentistry in 2021. The article was titled 《In Vitro Surface Investigation of Calcium Fluoride-like Precipitation on Human Enamel after Topical Treatment with the Organic Fluoride Nicomethanol Hydrofluoride.》.Computed Properties of C6H7NO The article contains the following contents:

PURPOSE: The topical fluoride treatment of teeth can lead to a formation of CaF2-like material, which is considered to play a significant role in caries prevention. Different types of fluoride sources are applied. The aim of this study was to analyse the in vitro fluoridation effect of the lesser known organic fluoride compound nicomethanol hydrofluoride (NH) regarding fluoride accumulation and morphological changes on dental enamel surfaces. Materials and Methods: The fluoridation effect was investigated by scanning electron microscopy (SEM) and energy dispersive x-ray analysis (EDX) after treatment with fluoride solutions at a concentration of 1350 ppm F - and a pH value of 5.5. NH was tested against inorganic sodium fluoride (NaF) as reference. Fluoridation was done on pellicle-free and pellicle-covered enamel. Results: Formation of globular CaF2-like material was observed for both fluoride types. However, NH led to considerably higher calcium fluoride accumulation on the enamel surface as shown by both EDX and SEM. The globule diameters varied between 0.2 and 0.8 µm. Cross-sectional analysis revealed that the globular precipitates lay directly on the enamel surface; only the very surface-near volume was affected. No statistically significant difference of the fluoridation effect was measured with vs without saliva pre-treatment. Conclusion: The experiments showed a 6 times greater F - surface uptake on dental enamel with NH compared to sodium fluoride, thus suggesting an important role of NH during remineralization phases, fostering equilibrium between de- and remineralization. The experimental part of the paper was very detailed, including the reaction process of 3-Pyridinemethanol(cas: 100-55-0Computed Properties of C6H7NO)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Computed Properties of C6H7NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2022,Haure, Maxime; Nguyen, Thi Kim Chi; Cendres, Aurelie; Perino, Sandrine; Licandro, Helene; Wache, Yves published an article in European Food Research and Technology. The title of the article was 《Glycosidically bound volatile profiles of green and roasted coffee beans and aromatic potential of spent coffee ground》.Name: 3-Pyridinemethanol The author mentioned the following in the article:

Coffee volatile compounds formation has been studied for years and the main flavor precursors have been identified. Coffee glycosidically bound volatiles (GBVs) are still underexplored and, yet, can act as aroma precursors during the post-harvesting processing and roasting. Free volatile compounds and GBVs of green coffee beans (CB), roasted CB and spent coffee ground (SCG) were analyzed. Roasting led to the formation of a new GBVs pool from green to roasted CB and SCG. Most of the GBVs of green CB were hydrolyzed during roasting. On the other hand, pyrroles, cycloketones, pyridines and pyrans were identified for the first time as bound volatiles and occurred only after the roasting process. This study supports the importance of GBVs on coffee aroma formation during the post-harvest processing. The release of the GBVs of roasted CB during brewing could enhance the varietal aromas of industrial ready-to-drink coffees. Furthermore, the SCG GBVs could be used as a new source of natural flavours for perfume industries. The experimental part of the paper was very detailed, including the reaction process of 3-Pyridinemethanol(cas: 100-55-0Name: 3-Pyridinemethanol)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Name: 3-Pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts