Author: tianli

Zhang, Sai published the artcileInterfacial Effects of the CuO/GO Composite to Mediate the Side Reactions of N,N-Dimethylformamide Fragments, HPLC of Formula: 23351-09-9, the publication is ACS Applied Materials & Interfaces (2014), 6(24), 22174-22182, database is CAplus and MEDLINE.

The interface between nanocatalysts and graphene oxide (GO) has been found to play a crucial role in enhancing the catalytic activity and improving the selectivity of amination reactions in N,N-dimethylformamide (DMF). The composite catalysts of CuO/GO used for the catalytic coupling of aryl halides with amines in DMF can completely inhibit the side reaction between the aryl halides and fragments of DMF. With identical amounts of Cu-catalysts, the conversion of iodobenzene and the selectivity for the target product reached 100% when CuO/GO composite catalysts were employed, while these results were 70.3 and 42.8%, resp., when CuO catalysts were used alone. Exptl. evidence confirms that the interfacial effect of CuO/GO is the origination of the improved performance of composite catalysts, which has been found to efficiently transfer fragments of DMF to GO and avoid unexpected side reactions during the catalytic process.

ACS Applied Materials & Interfaces published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C7H16Cl2Si, HPLC of Formula: 23351-09-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Yuan-Yuan published the artcileProtective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize, Application In Synthesis of 96-20-8, the publication is Pest Management Science (2021), 77(1), 177-183, database is CAplus and MEDLINE.

Herbicide safeners mitigate crop damage without reducing herbicide efficacy. Here, the protective effects of phenoxyacetyl oxazolidine derivatives as potential safeners were evaluated with a view toward reducing injury caused by sulfonylurea herbicide nicosulfuron to sensitive maize varieties. Growth indexes demonstrated that the bioactivity of compound 9 (N-phenoxyacety-2-methyl-2,4-diethyl-1,3-oxazolidine) was superior to that of R-28725 and all other compounds tested. Compound 9 induced endogenous glutathione and upregulated glutathione-S-transferase (GST) in maize. Thus, it could enhance maize tolerance to nicosulfuron. Compared with the untreated water control group, the maximum reaction rate of GST was increased by 37.62%, while the maximum velocity of GST was decreased by 61.93% after treatment with compound 9. Acetolactate synthase relative activity was significantly enhanced in the case of treatment with compound 9, indicating the excellent protective effects of compound 9 against nicosulfuron in maize. The present work demonstrates that phenoxyacetyl oxazolidine derivatives are potentially efficacious as herbicide safeners and merit further investigation.

Pest Management Science published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is CBF6K, Application In Synthesis of 96-20-8.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yang, Yu published the artcileOptimization of medium composition for two-step fermentation of vitamin C based on artificial neural network-genetic algorithm techniques, Computed Properties of 526-98-7, the publication is Biotechnology & Biotechnological Equipment (2015), 29(6), 1128-1134, database is CAplus.

The production of 2-keto-L-gulonic acid (2-KGA) during the conversion from L-sorbose to 2-KGA in the two-step fermentation of vitamin C can be improved by using an efficient companion strain Bacillus subtilis A9 to facilitate the growth of Ketogulonicigenium vulgare and the production of 2-KGA. Two optimization models, namely response surface methodol. (RSM) and artificial neural network (ANN), were built to optimize the medium components for mixed-culture fermentation of 2-KGA. The root mean square error, R2 and the standard error of prediction given by the ANN model were 0.13%, 0.99% and 0.21%, resp., while the RSM model gave 1.89%, 0.84% and 2.9%, resp. This indicated that the fitness and the prediction accuracy of the ANN model were higher than those of the RSM model. Furthermore, using genetic algorithm (GA), the input space of the ANN model was optimized, predicting that the maximum 2-KGA production of 72.54 g·L-1 would be obtained at the GA-optimized concentrations of the medium components (L-sorbose, 92.5 g·L-1; urea, 10.2 g·L-1; corn steep liquor, 16 g·L-1; CaCO3, 3.96 g·L-1; MgSO4, 0.28 g·L-1). The 2-KGA production exptl. obtained using the ANN-GA-designed medium was 71.21 ± 1.53 g·L-1, which was in good agreement with the predicted value. The same optimization process may be used to improve the production during bacterial mixed-cultures fermentation by changing the fermentation parameters.

Biotechnology & Biotechnological Equipment published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H8N2, Computed Properties of 526-98-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xu, Tingting published the artcileResponse surface methodology to optimize medium for 2-keto-L-gulonic acid production by new strains system in two-step vitamin C fermentation, Recommanded Product: (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, the publication is Weishengwuxue Zazhi (2012), 32(2), 47-53, database is CAplus.

The ability of Bacillus pumilus HJ-04 to promote the production of vitamin C (VC) precursor, 2-keto-L-gulonic acid (2-KGA), by 2-KGA-producing strain is stronger than industrial Bacillus megaterium B2980 as associated bacteria in second step of two-step VC fermentation Six factors that affected the 2-KGA production by new strains system were analyzed and optimized adopting single factor test, Plackett-Burman (PB) design, and Box-Behnken design. The results indicated that L-sorbose, urea, and corn syrup were the noticeably influencing factors. The optimum acid-producing condition was 94.95 g/L of L-sorbose, 11.99 g/L of urea, 14.13 g/L of corn syrup. The acid production increased by 12.31 mg/mL, and the production period shortened by 6 h after the optimization.

Weishengwuxue Zazhi published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C20H23N3O2S, Recommanded Product: (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lu, Shu-xia published the artcileOptimization of medium composition for two-step fermentation of vitamin C using response surface methodology, Name: (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, the publication is Shipin Kexue (Beijing, China) (2013), 34(3), 202-206, database is CAplus.

2-Keto-L-gulonic acid production during the conversion process from L-sorbose to 2-keto-L-gulonic acid in the two-step fermentation of vitamin C was improved. An efficient companion strain of Bacillus subtilis A9 that facilitates the growth of Gluconobacter oxydans and the production of acids was screened from fresh milk. Based on single factor tests, the compositions of fermentation medium were optimized by response surface methodol. The results showed that three factors including L-sorbose, corn liquor and urea revealed significant impact on the production of 2-KGA. The optimal compositions included 90 g/L L-sorbose, 14.2 g/L corn liquor, 12.2 g/L urea, 4.1 g/L CaCO₃ and 0.2 g/L MgSO₄. Under the optimal medium, the yield of 2-keto-L-gulonic acid was up to 69.74 g/L, which was close to the theor. value of 70.33 g/L with the relative error of-0.59 g/L. The established regression equation for 2-KGA revealed excellent fitting. Therefore, it is credible and can be used for practical prediction.

Shipin Kexue (Beijing, China) published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Name: (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ma, Lijuan published the artcileCharacterization of the key aroma-active compounds in high-grade Dianhong tea using GC-MS and GC-O combined with sensory-directed flavor analysis, Related Products of alcohols-buliding-blocks, the publication is Food Chemistry (2022), 132058, database is CAplus and MEDLINE.

Dianhong tea (DHT) is popular for its pleasant caramel-like aroma. In this study, the aroma profile of high-grade DHT have been studied using gas chromatog.-mass spectrometry (GC-MS) and gas chromatog.-olfactometry (GC-O) combined with headspace solid phase microextraction (HS-SPME). A total of 52 aroma-active compounds were identified by GC-O coupled with aroma extract dilution anal. (AEDA) and odor specific magnitude estimation (Osme). Among them, quantification of 21 aroma-active compounds indicated that the content of linalool (5928μg/kg) was the highest in high-grade DHT, followed by phenylethanol (3923μg/kg) and phenylacetaldehyde (1801μg/kg). Sensory-directed aroma recombination and omission tests further verified that phenylacetaldehyde, linalool, geraniol and 3-ethyl-2,5-dimethylpyrazine were important contributors to the overall sensory characteristics of high-grade DHT which dominated mainly by floral, sweet and caramel-like odors. This work will provide a theor. reference for comprehensively understanding the aroma characteristic of DHT.

Food Chemistry published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Qiao, Lin published the artcileScreening of ToxCast Chemicals Responsible for Human Adverse Outcomes with Exposure to Ambient Air, COA of Formula: C9H12O, the publication is Environmental Science & Technology (2022), 56(11), 7288-7297, database is CAplus and MEDLINE.

Air pollution poses a major threat to global public health. Although there have been a few investigations into the relationships between organic pollutants and adverse outcomes, the responsible components and mol. mechanisms may be ignored. In this study, a suspect screening method combining comprehensive two-dimensional gas chromatog. – time-of-flight mass spectrometry (GC x GC-TOFMS) with Toxicity Forecaster (ToxCast) database was applied to analyze complex hydrophobic compounds in ambient air and prospectively figure out toxicol. significant compounds 76 ToxCast compounds were screened, including 7 pollutants receiving less attention and 5 chems. never published in the air previously. Given the concentrations, bioactivities, as well as absorption, distribution, metabolism, and excretion properties in vivo, 29 contaminants were assigned high priority since they had active biol. effects in the vascular, lung, liver, kidney, prostate and bone tissues. Phenotypic linkages of key pollutants to potential mechanistic pathways were explored by systems toxicol. A total of 267 chem.-effect pathways involving 29 toxicants and 31 mol. targets were mapped in bipartite network, in which 12 key pathogenic pathways were clarified, which not only provided the evidence supporting previous hypothesis but also provided new insights into the mol. targets. The results would facilitate the development of pollutant priority control, population intervention and clin. therapeutic strategies so as to substantially reduce human health hazards induced by urban air.

Environmental Science & Technology published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C9H12O, COA of Formula: C9H12O.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Meijie published the artcileEffect of hemabate combined with oxytocin on bleeding after cesarean section, Recommanded Product: 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, the publication is Xin Zhongyi (2015), 47(5), 185-186, database is CAplus.

Objective: To observe the effect of hemabate combined with oxytocin on bleeding after cesarean section. Methods: 116 cases of cesarean section women were randomly divided into a control group and an observation group. The control group received hemabate, while the observation group addnl. received oxytocin. Results: The total effective rate in the observation group was significantly higher than that in the control group. After treatment, the postpartum hemorrhage volume significantly decreased in both groups, and the observation group was significantly lower than that in the control group. There were no serious adverse reactions in both groups. Conclusion: Hemabate combined with oxytocin for maternal postoperative cesarean section can significantly reduce postpartum hemorrhage and improve clin. effect.

Xin Zhongyi published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C44H28ClFeN4, Recommanded Product: 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barik, Chandan Kr published the artcileRuthenacyclic Carbamoyl Complexes: Highly Efficient Catalysts for Organosilane Hydrolysis, Safety of Triethylsilanol, the publication is European Journal of Inorganic Chemistry (2018), 2018(46), 4982-4986, database is CAplus.

The ruthenacyclic carbamoyl complexes [RuX{2-NHC(O)C₅H₃NR}(CO)₂(NCMe)] (R = H and Me; X = Br and SC₆H₃-o,o-Me₂) are excellent catalysts for the hydrolysis of organosilanes, particularly towards primary silanes, generating H under ambient conditions within seconds. These complexes are structural mimics of the [Fe]-hydrogenase active site and like the natural enzyme, a labile ligand at the 6th coordination site is essential to the catalytic activity.

European Journal of Inorganic Chemistry published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Safety of Triethylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barik, Chandan Kr published the artcileRuthenacyclic Carbamoyl Complexes: Highly Efficient Catalysts for Organosilane Hydrolysis, Recommanded Product: Triisopropylsilanol, the publication is European Journal of Inorganic Chemistry (2018), 2018(46), 4982-4986, database is CAplus.

The ruthenacyclic carbamoyl complexes [RuX{2-NHC(O)C₅H₃NR}(CO)₂(NCMe)] (R = H and Me; X = Br and SC₆H₃-o,o-Me₂) are excellent catalysts for the hydrolysis of organosilanes, particularly towards primary silanes, generating H under ambient conditions within seconds. These complexes are structural mimics of the [Fe]-hydrogenase active site and like the natural enzyme, a labile ligand at the 6th coordination site is essential to the catalytic activity.

European Journal of Inorganic Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Recommanded Product: Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts