Author: tianli

Tran, Chieu D. published the artcileChiral separation of amino acids by capillary electrophoresis with octyl-β-thioglucopyranoside as chiral selector, Synthetic Route of 85618-21-9, the publication is Journal of Chromatography A (2002), 978(1-2), 221-230, database is CAplus and MEDLINE.

1-S-Octyl-β-D-thioglucopyranoside (OTG) was evaluated as a chiral selector for the separation of dansylamino acids by capillary electrophoresis. Enantiomeric separations of the amino acids can be accomplished by judiciously adjusting the pH of the solution and the concentration of OTG. Better separation can be achieved, however, when OTG was used, not as a sole chiral selector but rather together with sodium dodecyl sulfate (SDS) and cyclodextrin (CD). Not only can this OTG-SDS-CD system provide better separation than OTG alone but also it can sep. compounds which cannot be separated when only CD or CD and SDS were used. All amino acids were baseline separated with this OTG-SDS-CD system at optimal conditions.

Journal of Chromatography A published new progress about 85618-21-9. 85618-21-9 belongs to alcohols-buliding-blocks, auxiliary class Tetrahydropyran,Chiral,sulfides,Alcohol, name is (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C8H15ClN2, Synthetic Route of 85618-21-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Soeta, Takahiro published the artcileN-Heterocyclic Carbene-Catalyzed Chemoselective Monoacylation of 1,n-Linear Diols, Application In Synthesis of 111-29-5, the publication is Organic Letters (2021), 23(21), 8138-8142, database is CAplus and MEDLINE.

This paper discusses the N-heterocyclic carbene (NHC)-catalyzed redox monoacylation of 1,n-linear diols using α-benzoyloxyaldehydes. The reactions afforded monoacylated diols in moderate to good selectivities and chem. yields. Authors original NHC bearing a pyridine moiety plays an important role in achieving good chemoselectivities. A wide range of 1,n-linear diols were successfully applied to this reaction.

Organic Letters published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C12H16O3, Application In Synthesis of 111-29-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mori, Jiro F. published the artcileMultispecies diesel fuel biodegradation and niche formation are ignited by pioneer hydrocarbon-utilizing proteobacteria in a soil bacterial consortium, Quality Control of 86-48-6, the publication is Applied and Environmental Microbiology (2021), 87(1), e02268, database is CAplus and MEDLINE.

A soil bacterial consortium that was grown on diesel fuel and consisted of more than 10 members from different genera was maintained through repetitive subculturing and was utilized as a practical model to investigate a bacterial community that was continuously exposed to petroleum hydrocarbons. Through metagenomics analyses, consortium member isolation, growth assays, and metabolite identification which supported the linkage of genomic data and functionality, two pioneering genera, Sphingobium and Pseudomonas, whose catabolic capabilities were differentiated, were found to be responsible for the creation of specialized ecol. niches that were apparently occupied by other bacterial members for survival within the consortium. Coexisting genera Achromobacter and Cupriavidus maintained their existence in the consortium through metabolic dependencies by utilizing hydrocarbon biotransformation products of pioneer metabolism, which was confirmed through growth tests and identification of biotransformation products of the isolated strains. Pioneering Sphingobium and Pseudomonas spp. utilized relatively water-insoluble hydrocarbon parent compounds and facilitated the development of a consortium community structure that resulted in the creation of niches in response to diesel fuel exposure which were created through the production of more-water-soluble biotransformation products available to cocolonizers. That these and other organisms were still present in the consortium after multiple transfers spanning 15 years provided evidence for these ecol. niches. Member survival through occupation of these niches led to robustness of each group within the multispecies bacterial community. Overall, these results contribute to our understanding of the complex ecol. relationships that may evolve during prokaryotic hydrocarbon pollutant biodegradation

Applied and Environmental Microbiology published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Quality Control of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tanioka, Masaru published the artcileStepwise structural and fluorescent colour conversion in rhodamine analogues based on light and acid stimulations, Category: alcohols-buliding-blocks, the publication is Journal of Materials Chemistry C: Materials for Optical and Electronic Devices (2020), 8(2), 543-549, database is CAplus.

The research and development of multi-stimuli, multi-responsive mols. have attracted considerable attention in chem., biol., and material science. Herein, the authors propose a multi-stimuli-responsive multi-fluorescence system in a single mol. This system is based on the isomerization that involves ring-opening/closing reactions of spirolactones of rhodamine analogs (ABPXs), developed by the authors’ group, which can be independently controlled by light and chem. stimuli. UV light irradiation opens one of the spirolactones to give thermally stable colored isomer (Z) in solution Detailed synthetic and theor. studies reveal that the ring-opening reaction of ABPXs proceeds via the formation of a photo-induced charge separated state, followed by the recombination of the biradicals. Furthermore, the authors explore the structure-kinetic relations and demonstrate that the introduction of electron-donating substituents into the xanthene ring can tune the lifetime of the photo-generated isomer. Chem. stimulation by an acid further promotes the ring-opening reaction to give a red shifted isomer (D). These light and chem. input signals can be converted into output signals of distinct color and fluorescence. The multi-stimuli-responsive multi-color fluorescence could be distinctively expressed through the combinatorial logic gate.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C30H24BrCuN2P, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hirano, Tomohiro published the artcileSyndiotactic-specific radical polymerization of N-isopropylacrylamide in toluene at low temperatures in the presence of silyl alcohols, Application In Synthesis of 17877-23-5, the publication is Polymer International (2012), 61(6), 966-970, database is CAplus.

The radical polymerization of N-isopropylacrylamide was carried out in toluene at low temperatures in the presence of silyl alcs., such as triethylsilanol. Poly(N-isopropylacrylamide) with a racemo dyad content of 75% was obtained at – 80° with a 4:1 triethylsilanol to monomer ratio loading. NMR anal. suggests that the mechanism for syndiotactic induction, in the presence of silyl alcs., may be similar to that observed with alkyl alcs. In this case, a 1:2 complex formation, via hydrogen bonding interactions, leads to the induction of syndiotactic specificity. Copyright © 2012 Society of Chem. Industry.

Polymer International published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Application In Synthesis of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shibata, Kentaro published the artcileHomopolymer-block-Alternating Copolymers Composed of Acrylamide Units: Design of Transformable Divinyl Monomers and Sequence-Specific Thermoresponsive Properties, Product Details of C8H5F3O3, the publication is Journal of the American Chemical Society (2022), 144(22), 9959-9970, database is CAplus and MEDLINE.

In this work, we synthesized an acrylamide-based terpolymer that is a block copolymer composed of an AB alternating copolymer and a C homopolymer. The key to the unprecedented achievement is rational design of an acrylate-acrylamide divinyl monomer carrying CF₃-substituted salicylic acid ester bonds (AAm-CF₃) to realize the efficient and selective cyclopolymn. as well as the quant. transformation of the resultant cyclorepeating units. The selectivity in the cyclopolymn. and the pendant transformation ability were evaluated through reactivity ratios of the corresponding model monomers and quant. aminolysis reactions of the model compound The cyclopolymn. via the photoinduced electron transfer-reversible addition-fragmentation chain transfer (PET-RAFT) process with a macrochain-transfer agent and subsequent aminolysis reaction afforded the homopolymer-block-alternating copolymer. The sequence-controlled terpolymer exhibited a very unique thermal response behavior in water that was strikingly different from the corresponding sequence-uncontrolled terpolymers, such as homopolymer-block-statistical copolymers and all statistical terpolymers, despite the fact that the structure cannot be distinguished by ¹H NMR.

Journal of the American Chemical Society published new progress about 328-90-5. 328-90-5 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Carboxylic acid,Benzene,Phenol, name is 2-Hydroxy-4-(trifluoromethyl)benzoic acid, and the molecular formula is C9H10O4, Product Details of C8H5F3O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nojima, Susumu published the artcileSelective Oxidation with Aqueous Hydrogen Peroxide by [PO₄{WO(O₂)₂}₄]^3- Supported on Zinc-Modified Tin Dioxide, Computed Properties of 597-52-4, the publication is ChemCatChem (2015), 7(7), 1097-1104, database is CAplus.

The supported phosphorus-containing tetranuclear peroxotungstate ([PO₄{WO(O₂)₂}₄]^3-, denoted by PW4) catalysts by using zinc-modified SnO₂ supports with different zinc contents [PW₄-Zn(x)/SnO₂, in which x denotes the zinc content (wt%)] were prepared The supported catalysts, in particular PW4-Zn(0.8)/SnO₂, could act as efficient and reusable heterogeneous catalysts for selective oxidation with aqueous H₂O₂ as the terminal oxidant. The catalytic performance of PW4-Zn(0.8)/SnO₂ was much superior to those of the corresponding homogeneous analog THA₃PW4 (THA = tetra-n-hexylammonium) and the previously reported tungstate-based heterogeneous catalysts such as our W-Zn/SnO₂. In the presence of PW4-Zn(0.8)/SnO₂, various types of organic substrates such as alkenes, amines, silanes, and sulfides could be converted into the corresponding oxygenated products in high to excellent yields by using near-stoichiometric amounts of H₂O₂ with respect to the substrates (typically 1.2 equivalent). The PW4 species interacting with highly dispersed Zn²⁺ species on SnO₂ likely plays an important role in the present oxidation

ChemCatChem published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Computed Properties of 597-52-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ishimoto, Ryo published the artcileHighly selective oxidation of organosilanes to silanols with hydrogen peroxide catalyzed by a lacunary polyoxotungstate, COA of Formula: C9H22OSi, the publication is Angewandte Chemie, International Edition (2009), 48(47), 8900-8904, S8900/1-S8900/11, database is CAplus and MEDLINE.

Divacant lacunary polyoxotungstate (Bu₄N⁺)₄[γ-SiW₁₀O₃₄(H₂O)₂] (1) is an efficient homogeneous catalyst for highly selective oxidation of organosilanes to silanols with 30-60 % aqueous H₂O₂. Various kinds of silanes, Ph₂MeSiH, Et₃SiH, (C₆H₁₃)₃SiH, ^tBuMe₂SiH, Bu₃SiH, ⁱPr₃SiH, (EtO)₃SiH, (BuO)₃SiH, RMe₂SiH (R = Ph, 4-MeOC₆H₄, 4-MeC₆H₄, 4-CF₃C₆H₄, ClCH₂, PhCC, PhCH:CH) containing aryl, alkyl, alkenyl, alkynyl, and alkoxy groups are chemoselectively converted into the corresponding silanols in high yields with only one equiv of aqueous H₂O₂.

Angewandte Chemie, International Edition published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, COA of Formula: C9H22OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ghiasi, Mina published the artcileConformational Analysis of Topiramate and Related Anion in the Solution and Interaction Between the Most Stable Conformer of Topiramate with Active Center of Carbonic Anhydrase Enzyme, Computed Properties of 20880-92-6, the publication is Journal of Carbohydrate Chemistry (2015), 34(2), 80-102, database is CAplus.

D. functional theory using the B3LYP/6-311++G** method was employed to calculate the details of the electronic structure and electronic energy of the carbonic anhydrase enzyme active center (CA); topiramate, a sulfamate substituted monosaccharide; and the complex between topiramate and CA. The calculated results indicate that topiramate appears to adopt a twist-boat conformation in the solution The conformational anal. around the S-N bond (H-N-S-O dihedral angle) in deprotonated topiramate shows that the conformers with a H-N-S-O torsion of 270, 0, and 180 degrees are the min., transition state, and maximum energy conformers, resp. The deprotonated form of topiramate is coordinated to the Zn²⁺ ion.

Journal of Carbohydrate Chemistry published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Computed Properties of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ye, Juntao published the artcileDirect α-alkylation of primary aliphatic amines enabled by CO₂ and electrostatics, Recommanded Product: 4,4-Diethoxybutan-1-amine, the publication is Nature Chemistry (2018), 10(10), 1037-1041, database is CAplus and MEDLINE.

Primary aliphatic amines are important building blocks in organic synthesis due to the presence of a synthetically versatile NH₂ group. N-functionalization of primary amines is well established, but selective C-functionalization of unprotected primary amines remains challenging. Here, we report the use of CO₂ as an activator for the direct transformation of abundant primary aliphatic amines into valuable γ-lactams under photoredox and hydrogen atom transfer (HAT) catalysis. Exptl. and computational studies suggest that CO₂ not only inhibits undesired N-alkylation of primary amines, but also promotes selective intermol. HAT by an electrostatically accelerated interaction between the in situ-generated neg. charged carbamate and the pos. charged quinuclidinium radical. This electrostatic attraction overwhelms the inherent bond dissociation energies which suggest that HAT should occur unselectively. We anticipate that our findings will open up new avenues for amine functionalizations as well as selectivity control in HAT reactions.

Nature Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C15H24BNO3, Recommanded Product: 4,4-Diethoxybutan-1-amine.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts