Author: tianli

Spiliopoulou, Nikoleta published the artcilePhotochemical metal-free aerobic oxidation of thiols to disulfides, SDS of cas: 4410-99-5, the publication is Green Chemistry (2021), 23(1), 546-551, database is CAplus.

A mild, inexpensive and green photochem. approach for the synthesis of both sym. and non-sym. disulfides, using metal-free and environmentally friendly conditions was reported. Utilizing phenylglyoxylic acid as the photoinitiator, common household bulbs as the light source and a simple inorganic salt as the additive, a versatile oxidation of thiols leading to products in excellent yields was described.

Green Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C11H14O4, SDS of cas: 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Limnios, Dimitris published the artcileOrganocatalytic Oxidation of Organosilanes to Silanols, Related Products of alcohols-buliding-blocks, the publication is ACS Catalysis (2013), 3(10), 2239-2243, database is CAplus.

The oxidation of organosilanes to silanols constitutes an attractive transformation for both industry and academia. Bypassing the need for stoichiometric oxidants or precious metal catalytic complexes, the first organocatalytic oxidation of silanes has been accomplished. Catalytic amounts of 2,2,2-trifluoroacetophenone, in combination with the green oxidant H₂O₂, lead to excellent to quant. yields in a short reaction time. A variety of alkyl, aryl, alkenyl, and alkynyl substituents can be tolerated, providing an easy, cheap, efficient, and practical solution to a highly desirable transformation.

ACS Catalysis published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Limnios, Dimitris published the artcileOrganocatalytic Oxidation of Organosilanes to Silanols, Synthetic Route of 17877-23-5, the publication is ACS Catalysis (2013), 3(10), 2239-2243, database is CAplus.

The oxidation of organosilanes to silanols constitutes an attractive transformation for both industry and academia. Bypassing the need for stoichiometric oxidants or precious metal catalytic complexes, the first organocatalytic oxidation of silanes has been accomplished. Catalytic amounts of 2,2,2-trifluoroacetophenone, in combination with the green oxidant H₂O₂, lead to excellent to quant. yields in a short reaction time. A variety of alkyl, aryl, alkenyl, and alkynyl substituents can be tolerated, providing an easy, cheap, efficient, and practical solution to a highly desirable transformation.

ACS Catalysis published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Synthetic Route of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Maness, Peter published the artcileSubstituent Effects on Temperature Dependence of Kinetic Isotope Effects in Hydride-Transfer Reactions of NADH/NAD⁺ Analogues in Solution: Reaction Center Rigidity Is the Key, Synthetic Route of 596-38-3, the publication is Organic Letters (2020), 22(15), 5963-5967, database is CAplus and MEDLINE.

Substituent effects on the temperature dependence of primary kinetic isotope effects, characterized by ΔE_a = E_aD – E_aH, for two series of the title reactions in acetonitrile were studied. The change from ΔE_a â‰?0 for a highly rigid system to ΔE_a > 0 for systems with reduced rigidities was observed The rigidities were controlled by the electronic and steric effects. This work replicates the observations in enzymes and opens a new research direction that studies structure-ΔE_a relationship.

Organic Letters published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Synthetic Route of 596-38-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Seitz, Ann-Katrin published the artcileConcentrated Aqueous Peroxodicarbonate: Efficient Electrosynthesis and Use as Oxidizer in Epoxidations, S-, and N-Oxidations, Related Products of alcohols-buliding-blocks, the publication is Angewandte Chemie, International Edition (2022), 61(25), e202117563, database is CAplus and MEDLINE.

Peroxodicarbonates are of substantial interest as potentially powerful and sustainable oxidizers but have so far been accessible only in low concentrations with unsatisfactory energy efficiency. Concentrated (> 0.9 mol L^-1) peroxodicarbonate solutions have now been made accessible by the electrolysis of aqueous K₂CO₃/Na₂CO₃/KHCO₃ solutions at high c.d. of 3.33 A cm^-2 in an efficiently cooled circular flow reactor equipped with a boron-doped diamond anode and a stainless-steel cathode. Their synthetic potential as platform oxidizers was clearly demonstrated in transformations including sulfoxidation, N-oxidation, and epoxidation

Angewandte Chemie, International Edition published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C8H11NO, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Seitz, Ann-Katrin published the artcileConcentrated Aqueous Peroxodicarbonate: Efficient Electrosynthesis and Use as Oxidizer in Epoxidations, S-, and N-Oxidations, Name: 2-Morpholinoethanol, the publication is Angewandte Chemie, International Edition (2022), 61(25), e202117563, database is CAplus and MEDLINE.

Peroxodicarbonates are of substantial interest as potentially powerful and sustainable oxidizers but have so far been accessible only in low concentrations with unsatisfactory energy efficiency. Concentrated (> 0.9 mol L^-1) peroxodicarbonate solutions have now been made accessible by the electrolysis of aqueous K₂CO₃/Na₂CO₃/KHCO₃ solutions at high c.d. of 3.33 A cm^-2 in an efficiently cooled circular flow reactor equipped with a boron-doped diamond anode and a stainless-steel cathode. Their synthetic potential as platform oxidizers was clearly demonstrated in transformations including sulfoxidation, N-oxidation, and epoxidation

Angewandte Chemie, International Edition published new progress about 622-40-2. 622-40-2 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Alcohol, name is 2-Morpholinoethanol, and the molecular formula is C12H23N3S, Name: 2-Morpholinoethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Karaman, Rafik published the artcileConversion of aromatic ketones, benzyl alcohols, and alkyl aryl ethers to aromatic hydrocarbons with lithium 4,4′-di-tert-butylbiphenyl radical anion, Name: 9-Phenyl-9H-xanthen-9-ol, the publication is Tetrahedron Letters (1990), 31(43), 6155-8, database is CAplus.

Treatment of THF solutions of the title compounds with excess lithium (or potassium) metal under ultrasonic irradiation in the presence of catalytic amounts of the electron-transfer agent 4,4′-di-t-butylbiphenyl caused conversions to aromatic hydrocarbons in good yields. Addition of 1 or 2 equiv of alkyl halides prior to aqueous ammonium chloride treatment during workup provided mono- or dialkylated products.

Tetrahedron Letters published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Name: 9-Phenyl-9H-xanthen-9-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Prosser, Kathleen E. published the artcile¹⁹F-Tagged metal binding pharmacophores for NMR screening of metalloenzymes, Recommanded Product: 2-Hydroxy-4-(trifluoromethyl)benzoic acid, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(40), 4934-4937, database is CAplus and MEDLINE.

This study demonstrates the screening of a collection of twelve ¹⁹F-tagged metal-binding pharmacophores (MBPs) against the Zn(II)-dependent metalloenzyme human carbonic anhydrase II (hCAII) by ¹⁹F NMR. The isomorphous replacement of Zn(II) by Co(II) in hCAII produces enhanced sensitivity and reveals the potential of ¹⁹F NMR-based techniques for metalloenzyme ligand discovery.

Chemical Communications (Cambridge, United Kingdom) published new progress about 328-90-5. 328-90-5 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Carboxylic acid,Benzene,Phenol, name is 2-Hydroxy-4-(trifluoromethyl)benzoic acid, and the molecular formula is C8H5F3O3, Recommanded Product: 2-Hydroxy-4-(trifluoromethyl)benzoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Murayama, Eigoro published the artcileMetal-catalyzed organic photoreactions. Evidence for the long-range electron-transfer mechanism in the uranyl- or iron(III)-catalyzed photoreactions of olefins, Safety of 2-Methyl-3-bromo-2-butanol, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1980), 947-9, database is CAplus.

A mechanism for the title reaction was proposed involving interligand electron transfer from the electron-donating ligand (OH^– or Cl^–) to O₂ through the metal ion and olefin mol. This was verified for the UO₂²⁺-catalyzed photochem. formation of bromohydrins from olefins and polyhalogenated compounds by correlation of the reactivities and product ratios with the half-wave reduction potentials of the polyhalogenated compounds

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 2588-77-4. 2588-77-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 2-Methyl-3-bromo-2-butanol, and the molecular formula is C5H11BrO, Safety of 2-Methyl-3-bromo-2-butanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ishikawa, Nobuo published the artcilePreparation of trifluoromethylated allylic alcohols from trifluoroacetaldehyde and organometallic compounds, Application In Synthesis of 83706-94-9, the publication is Journal of Fluorine Chemistry (1984), 24(4), 419-30, database is CAplus.

A number of allylic alcs. bearing a CF₃ group at the α- or γ-position, and α-trifluoromethylated γ-enols and -ynols were prepared by the reaction of CF₃CHO with a variety of organometallic compounds Most of the Reformatskii- or Grignard-type reactions required promotion by ultrasound. E.g., Reformatskii-type reaction of CF₃CHO and BrCH₂CO₂Et in the presence of Zn powder and ultrasound gave CF₃CH(OH)CH₂CO₂Et, which was dehydrated, then reduced (LiAlH₄/AlCl₃) to give CF₃CH:CHCH₂OH. Also prepared were RCH:CHCH(OH)CF₃ (R = Bu, Ph), RCMe:CHCH(OH)CF₃ (same R), CF₃CH(OH)CHR¹CH:CH₂ (R¹ = H, Me, Ph), and CF₃CH(OH)CH₂CCH.

Journal of Fluorine Chemistry published new progress about 83706-94-9. 83706-94-9 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is (E)-4,4,4-Trifluorobut-2-en-1-ol, and the molecular formula is C4H5F3O, Application In Synthesis of 83706-94-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts