Author: tianli

Kolacinska, Kamila published the artcileApplication of new covalently-bound diglycolamide sorbent in sequential injection analysis flow system for sample pretreatment in ICP-MS determination of 239Pu at ppt level, Synthetic Route of 110-99-6, the main research area is diglycolamide sorbent sequential injection analysis pretreatment plutonium ICP MS; Diglycolamide; ICP-MS; Nuclear reactor coolant; Plutonium; Sequential injection analysis; Solid-phase extraction.

Diglycolamide ligands are widely applied in the anal. of radionuclides, especially lanthanides and actinides. They are used in liquid-liquid extraction procedures or in solid-phase extraction sorbents where they are adsorbed on the surface of hydrophobic polymers. The main objective of this study was to synthesize the N,N,N’N’-tetrahexyl diglycolamide with one vinyl terminating group (vTHDGA) for further covalent immobilization on the polystyrene-divinylbenzene polymeric support. The obtained complexing resin (THDGA) was employed for the mechanized sample pretreatment in the Sequential Injection Anal. – Lab-on-Valve (SIA-LOV) flow system for the determination of 239Pu using ICP-MS detection. The anal. procedure was optimized in terms of selectivity towards several other radionuclides and elements forming potentially isobaric interferences in mass spectrometry. For 100 mL volume of sample to be analyzed, the method detection limit (MDL) was 96 mBq L-1 (42 pg L-1). The developed method was employed for the determination of 239Pu in real samples of a nuclear reactor coolant and spent fuel pool water from a nuclear reactor.

Talanta published new progress about Affinity. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Synthetic Route of 110-99-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Serna, Sonia published the artcileConstruction of N-Glycan Microarrays by Using Modular Synthesis and On-Chip Nanoscale Enzymatic Glycosylation, Product Details of C13H19NO3, the main research area is construction glycan microarray modular synthesis chip nanoscale enzymic glycosylation.

An effective chemoenzymic strategy is reported that has allowed the construction, for the first time, of a focused microarray of synthetic N-glycans. Based on modular approaches, a variety of N-glycan core structures have been chem. synthesized and covalently immobilized on a glass surface. The printed structures were then enzymically diversified by the action of three different glycosyltransferases in nanodroplets placed on top of individual spots of the microarray by a printing robot. Conversion was followed by lectin binding specific for the terminal sugars. This enzymic extension of surface-bound ligands in nanodroplets reduces the amount of precious glycosyltransferases needed by seven orders of magnitude relative to reactions carried out in the solution phase. Moreover, only those ligands that have been shown to be substrates to a specific glycosyltransferase can be individually chosen for elongation on the array. The methodol. described here, combining focused modular synthesis and nanoscale on-chip enzymic elongation, could open the way for the much needed rapid construction of large synthetic glycan arrays.

Chemistry – A European Journal published new progress about Affinity. 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Product Details of C13H19NO3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, Weihong published the artcileMajor constituents of cannabis vape oil liquid, vapor and aerosol in California vape oil cartridge samples, Computed Properties of 124-76-5, the main research area is cannabis vape oil liquid vapor aerosol major constituent GCMS; EVALI (e-cigarette or vaping product use-associated lung injury); GC-MS; aerosol; delta-9 tetrahydrocannabinol; nontarget; toxin; vape oil; vapor.

During the E-cigarette or Vaping product use Associated Lung Injury (EVALI) outbreak of August 2019 to Feb. 2020, the California Department of Public Health, Food and Drug Laboratory Branch received numerous cannabis vape oil cartridge investigation samples from throughout the state. Many of these products were directly linked to patients; others were collected as part of investigations. We determined the major ingredients and additives in twelve unused cannabis vape oil cartridge samples obtained before (n = 2) and during the EVALI outbreak (n = 10) in California from Sept. 2018 to Dec. 2019. We tested for major constituents in vape oil liquid, vape oil vapor, and vape oil aerosol phases. A nontargeted Gas Chromatog. Mass Spectrometry direct injection screening method was developed for vape oils, a headspace heating module used for vape oil vapors and a solid-phase microextraction (SPME) vaping rig for aerosols generated by vaping. We have identified more than 100 terpenes and natural extracts, 19 cannabinoids, and other potential toxic additives such as Vitamin E Acetate, Polyethylene Glycols, and Medium Chain Triglycerides. We determined more terpenes and minor cannabinoids can be produced via vaporizing and aerosolizing the vape oil. Delta9-THC and potential toxic additives were found at lower levels in the vapor and aerosol than in the vape liquid

Frontiers in Chemistry (Lausanne, Switzerland) published new progress about Aerosols. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Azeem, Hafiz Abdul published the artcileExtending the scope of dispersive liquid-liquid microextraction for trace analysis of 3-methyl-1,2,3-butanetricarboxylic acid in atmospheric aerosols leading to the discovery of iron(III) complexes, Recommanded Product: n-Octanol, the main research area is dispersive liquid microextraction trace analysis methylbutanetricarboxylic acid; atm aerosol iron complex monoterpene complexation vegetation; Biogenic secondary organic aerosol; Dispersive liquid–liquid microextraction; MBTCA; Metal complexes; Trace analysis.

3-Methyl-1,2,3-butanetricarboxylic acid (MBTCA) is a secondary organic aerosol and can be used as a unique emission marker of biogenic emissions of monoterpenes. Seasonal variations and differences in vegetation cover around the world may lead to low atm. MBTCA concentrations, in many cases too low to be measured. Hence, an important tool to quantify the contribution of terrestrial vegetation to the loading of secondary organic aerosol may be compromised. To meet this challenge, a dispersive liquid-liquid microextraction (DLLME) method, known for the extraction of hydrophobic compounds, was extended to the extraction of polar organic compounds like MBTCA without compromising the efficiency of the method. The extraction solvent was fine-tuned using tri-n-octyl phosphine oxide as additive. A multivariate exptl. design was applied for deeper understanding of significant variables and interactions between them. The optimum extraction conditions included 1-octanol with 15% tri-n-octyl phosphine oxide (weight/weight) as extraction solvent, MeOH as dispersive solvent, 25% NaCl dissolved in 5 mL sample (weight/weight) acidified to pH 2 using HNO3, and extraction time of 15 min. A limit of detection of 0.12 pg/m3 in air was achieved. Also, unique complexation behavior of MBTCA with Fe(III) was found when analyzed with ultra-HPLC coupled with electrospray ionization-quadrupole time-of-flight mass spectrometry (UHPLC-ESI-QToF). A comprehensive overview of this complexation behavior of MBTCA was examined with systematically designed experiments This newly discovered behavior of MBTCA will be of interest for further research on organometallic photooxidation chem. of atm. aerosols.

Analytical and Bioanalytical Chemistry published new progress about Aerosols. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ugbabe, Grace E. published the artcileChemo-microscopy of the leaves and GC-MS analyses of oils from different parts of Lantana camara linn grown in Nigeria, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Lantana camara linn chemomicroscopy GCMS analyses.

Chemo-microscopic anal. of Lantana camara Linn revealed the presence of lignin, starch, cellulose, oxalate crystals, tannin, oils, proteins and absence of mucilage in the leaves while the flowers showed the presence of all tested metabolites except mucilage and lignin. The GC-MS anal. of volatile oils of different parts (leaves, flowers, fruits) obtained by hydro-distillation was carried out. The total components detected in the oil of the leaf were 48, the flower oil had 49, and the fruit oil had 14 compounds, the major components common in the parts studied were: eucalyptol, beta-caryophyllene and alpha-caryophyllene. The components with the highest percentage compositions in the leaves were: gamma-terpinene (10.24%), eucalyptol (9.36%), alpha-pinene (5.82%), beta-caryophyllene (5.13%). In the flowers the components that had the highest composition were: eucalyptol (7.65%), trans-nerolidol (7.17%), beta-caryophyllene (6.95%), sabinene (6.29%), 14-hexadecatetraenyl acetate (5.82%), alpha-caryophyllene (5.81%) and in the fruits the components that had the highest composition were: phytol (23.04%), octadec-9-enoic acid (15.50%), beta-caryophyllene (13.57%), sabinene (9.66%), nhexadecanoic acid (9.51%), alpha-caryophyllene (6.97%) and trans-nerolidol (6.93%). The chemo-microscopic and GC-MS characterization of Lantana camara can be used for identification and quality control of the L. camara as a crude drug. Volatile oil constituents found in the different parts of the plant find applications in flavorings, fragrances or perfumery, cough suppressant, manufacture of cosmetic products, manufacture of detergents, soaps, emulsifying agent, manufacture of synthetic vitamin E and vitamin K1 as well as antiinflammatory, anti-bacterial and anti-fungal agents and manufacture of aerosol product and insecticides.

European Journal of Biomedical and Pharmaceutical Sciences published new progress about Aerosols. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yi-Fan published the artcileTreatment of particle/gas partitioning using level III fugacity models in a six-compartment system, HPLC of Formula: 111-87-5, the main research area is particle gas partitioning fugacity model six compartment system; Equilibrium; Fugacity model; Particle/gas partition; SVOCs; Steady state.

In this paper, two level III fugacity models are developed and applied using an environmental system containing six compartments, including air, aerosols, soil, water, suspended particulate matters (SPMs), and sediments, as a “”unit world””. The first model, assumes equilibrium between air and aerosols and between water and SPMs. These assumptions lead to a four-fugacity model. The second model removes these two assumptions leading to a six-fugacity model. The two models, compared using four PBDE congeners, BDE-28, -99, -153, and -209, with a steady flux of gaseous congeners entering the air, lead to the following conclusions. 1. When the octanol-air partition coefficient (KOA) is less than 1011.4, the two models produce similar results; when KOA > 1011.4, and especially when KOA > 1012.5, the model results diverge significantly. 2. Chems. are in an imposed equilibrium in the four-fugacity model, but in a steady state and not necessary an equilibrium in the six-fugacity model, between air and aerosols. 3. The results from the six-fugacity model indicate an internally consistent system with chems. in steady state in all six compartments, whereas the four-fugacity model presents an internally inconsistent system where chems. are in equilibrium but not a steady state between air and aerosols. 4. Chems. are mass balanced in air and aerosols predicted by the six-fugacity model but not by the four-fugacity model. If the mass balance in air and aerosols is achieved in the four-fugacity model, the condition of equilibrium between air and aerosols will be no longer valid.

Chemosphere published new progress about Aerosols. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, HPLC of Formula: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Ziyang published the artcileHydrophobic and thermal-insulating aerogels based on rigid cellulose nanocrystal and elastic rubber, Synthetic Route of 7575-23-7, the main research area is hydrophobic thermal insulating aerogel cellulose nanocrystal elastic rubber; Aerogels; Cellulose nanocrystals; Click reaction; Rubber.

Inspired from the ancient China philosophy of “”coupling hardness with softness””, we attempted the combination of rigid cellulose nanocrystals (CNC) and elastic rubbers to solve the limitations of structural brittleness and water sensitivity of CNC-based aerogels. Three rubber chains with the different chem. structures (silicon rubber, 1,2-polybutadiene, styreneic block copolymer) were covalently bonded on the CNC porous skeleton based on thiol-ene click chem., to fabricate the CNC/rubber composite aerogels. With the introduction of moderate loading levels of rubber, the composites aerogels exhibited low d. and shrinkage, high porosity and sp. surface area and improved mech. performance. Furthermore, the presence of rubber components completely changed the hydrophilic nature of cellulose skeleton as the hydrophobic aerogels, contributing the superior solvents resistance and self-cleaning property. With their advantages on mech. stability, heat insulation and hydrophobicity, the fabricated aerogels in this study exhibited the high added values in various potential applications.

Carbohydrate Polymers published new progress about Aerogels. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Synthetic Route of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Napolitano, Gaetana published the artcileOxidative damage and mitochondrial functionality in hearts from KO UCP3 mice housed at thermoneutrality, Formula: C4H6O5, the main research area is UCP oxidative damage heart mitochondria thermoneutrality phosphorylation; Calnexin; EIF2α; GRP78 BIP; Heart; Hsp 60; Mitochondrial complexes; Oxidative stress; Oxygen consumption; Thermoneutrality; UCP3.

The antioxidant role of mitochondrial uncoupling protein 3 (UCP3) is controversial. This work aimed to investigate the effects of UCP3 on the heart of mice housed at thermoneutral temperature, an exptl. condition that avoids the effects of thermoregulation on mitochondrial activity and redox homeostasis, preventing the alterations related to these processes from confusing the results caused by the lack of UCP3. WT and KO UCP3 mice were acclimatized at 30°C for 4 wk and hearts were used to evaluate metabolic capacity and redox state. Tissue and mitochondrial respiration, the activities of the mitochondrial complexes, and the protein expression of mitochondrial complexes markers furnished information on mitochondrial functionality. The levels of lipid and protein oxidative damage markers, the activity of antioxidant enzymes, the reactive oxygen species levels, and the susceptibility to in vitro Fe-ascorbate-induced oxidative stress furnished information on redox state. UCP3 ablation reduced tissue and mitochondrial respiratory capacities, not affecting the mitochondrial content. In KO UCP3 mice, the mitochondrial complexes activities were lower than in WT without changes in their content. These effects were accompanied by an increase in the level of oxidative stress markers, ROS content, and in vitro susceptibility to oxidative stress, notwithstanding that the activities of antioxidant enzymes were not affected by UCP3 ablation. Such modifications are also associated with enhanced activation/phosphorylation of EIF2α, a marker of integrated stress response and endoplasmic reticulum stress (GRP778 BIP). The lack of UCP3 makes the heart more prone to oxidative insult by reducing oxygen consumption and increasing ROS. Our results demonstrate that UCP3 helps the cell to preserve mitochondrial function by mitigating oxidative stress.

Journal of Physiology and Biochemistry published new progress about Ablation. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Formula: C4H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hodges, Geoff published the artcileA comparison of log Kow (n-octanol-water partition coefficient) values for non-ionic, anionic, cationic and amphoteric surfactants determined using predictions and experimental methods, COA of Formula: C8H18O, the main research area is partition coefficient surfactant prediction.

Surfactants are widely used across the globe both in industrial and consumer products. The n-octanol/water partition ratio or coefficient (log Kow) and n-octanol/water distribution coefficient (log D) are key parameters in environmental risk assessment of chems. as they are often used to estimate the environmental fate and bioavailability and thus exposure and toxicity of a compound Determining log Kow data for surfactants is a tech. challenge due to their amphiphilic properties. Currently several existing exptl. OECD methods (e.g. slow-stirring, HPLC, solubility ratio) and QSPR models are available for log Kow/D measurement or prediction. However, there are concerns that these methods have not been fully validated for surfactants and may not be applicable due to the specific phase behavior of surfactants. Results: The current methods were evaluated for the four surfactant classes (non-ionic, anionic, cationic and amphoteric). The solubility ratio approach, based on comparative n-octanol and water solubility measurements, did not generate robust or accurate data. The HPLC method generates consistently higher log Kow values than the slow-stirring method for non-ionics, but this pos. bias could be removed using reference surfactants with log Kow values determined using the slow-stirring method. The slow-stirring method is the most widely applicable exptl. method for generating log Kow/D data for all the surface-active test compounds Generally, QSPR-predicted log Kow/D values do not correlate well with exptl. values, apart for the group of non-ionic surfactants. Relatively, large differences in predicted log Kow/D values were observed when comparing various QSPR models, which were most noticeable for the ionised surfactants. Conclusions: The slow-stirring method is the most widely applicable exptl. method for generating log Kow/D data for all the four surfactant classes. A weight of evidence approach is considered appropriate for non-ionic surfactants using exptl. and model predications. However, it is more difficult to apply this approach to ionisable surfactants. Recommendations are made for the preferred existing QSPR predictive methods for determination of log Kow/D values for the surfactant classes. Investigation of newer alternative exptl. log Kow methods as well as more biol. relevant and methodol. defensible alternative methods for describing partitioning of surfactants are recommended.

Environmental Sciences Europe published new progress about Partition. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, COA of Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hanson, Kaila B. published the artcileEstimating n-octanol-water partition coefficients for neutral highly hydrophobic chemicals using measured n-butanol-water partition coefficients, Category: alcohols-buliding-blocks, the main research area is octanol butanol water partition coefficient; Collander equation; n-Butanol/water partition coefficients; n-octanol/water partition coefficients (K(OW)).

Direct measurement of the n-octanol partition coefficients (KOW) for highly hydrophobic organic chems. is extremely difficult because of the extremely low concentrations present in the water phase. n-Butanol/water partition coefficients (KBW) are generally much lower than KOW due to the increased solubility of solute in the alc. saturated aqueous phase, and therefore become easier to measure. We measured the KBW for 25 neutral organic chems. having measured log KOWs ranging from 2 to 9 and 4 addnl. highly hydrophobic chems., with unmeasured KOWs, having estimated log KOWs ranging from 6 to 18. The measured log KBW and log KOW values were linearly related, r2 = 0.978, and using the regression developed from the data, KOWs were predicted for the 4 highly hydrophobic chems. with unmeasured KOWs. The resulting predictions were orders of magnitude lower than those predicted by a variety of computational models and suggests the estimates of KOW in the literature for highly hydrophobic chems. (i.e., log KOW greater than 10) are likely incorrect by several orders of magnitude.

Chemosphere published new progress about Partition. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts