Author: tianli

Sam, Brannon published the artcileRuthenium-Catalyzed C-C Coupling of Fluorinated Alcohols with Allenes: Dehydrogenation at the Energetic Limit of β-Hydride Elimination, Product Details of C4H5F3O, the publication is Angewandte Chemie, International Edition (2015), 54(18), 5465-5469, database is CAplus and MEDLINE.

Ruthenium(II) complexes catalyze the C-C coupling of 1,1-disubstituted allenes and fluorinated alcs. to form homoallylic alcs. bearing all-carbon quaternary centers with good to complete levels of diastereoselectivity. Whereas fluorinated alcs. are relatively abundant and tractable, the corresponding aldehydes are often not com. available because of their instability.

Angewandte Chemie, International Edition published new progress about 83706-94-9. 83706-94-9 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is (E)-4,4,4-Trifluorobut-2-en-1-ol, and the molecular formula is C4H5F3O, Product Details of C4H5F3O.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sam, Brannon published the artcileRuthenium-Catalyzed C-C Coupling of Fluorinated Alcohols with Allenes: Dehydrogenation at the Energetic Limit of β-Hydride Elimination, Application In Synthesis of 2240-88-2, the publication is Angewandte Chemie, International Edition (2015), 54(18), 5465-5469, database is CAplus and MEDLINE.

Ruthenium(II) complexes catalyze the C-C coupling of 1,1-disubstituted allenes and fluorinated alcs. to form homoallylic alcs. bearing all-carbon quaternary centers with good to complete levels of diastereoselectivity. Whereas fluorinated alcs. are relatively abundant and tractable, the corresponding aldehydes are often not com. available because of their instability.

Angewandte Chemie, International Edition published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Application In Synthesis of 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ding, Haohao published the artcileA phosphorus/sulfur-containing compound toward simultaneously endowing epoxy resin with good flame retardancy and high transparency, Computed Properties of 80-09-1, the publication is Journal of Applied Polymer Science (2022), 139(26), e52431, database is CAplus.

A phosphorus/sulfur-containing compound (sulfonylbis(3,1-phenylene) bis(diphenyl-phosphinate), named as SBPDPP) is designed and synthesized by nucleophilic substitution reaction between diphenylphosphinyl chloride and 4,4-dihydroxydiphenylsulfone, and its chem. structure is verified by Fourier transform IR, ¹H and ³¹P NMR. The incorporation of SBPDPP accelerates the curing process but decreases the glass transition temperature and the crosslinking d. of the epoxy resin (EP). The cured EP with 6 wt% SBPDPP passes UL-94 V0 rating and gives limited oxygen index value of 38.8%, meanwhile maintaining 90% of the transmittance of the pure EP. Its peak heat release rate, total heat release, total smoke production, and total smoke rate are reduced by 40.8%, 42.0%, 26.3%, and 21.9% in comparison with the pure EP, demonstrating that the SBPDPP improved simultaneously the fire safety and smoke suppression. The comprehensive anal. of the char residues after cone calorimeter test and the volatile gasses during the pyrolysis demonstrates that the SBPDPP exerted dual flame retardant effect in the gas and condensed phase. The cured FREPs have promising applications that requiring flame retardancy and maintaining transparency.

Journal of Applied Polymer Science published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Computed Properties of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Fan, Lingling published the artcileSynthesis and antifungal activity of imidazo[1,2-b]pyridazine derivatives against phytopathogenic fungi, Safety of 2-Morpholinoethanol, the publication is Bioorganic & Medicinal Chemistry Letters (2020), 30(14), 127139, database is CAplus and MEDLINE.

A series of 3,6-disubstituted imidazo[1,2-b]pyridazine derivatives were synthesized and characterized with spectroscopic analyses. The antifungal activities of these compounds against nine phytopathogenic fungi were evaluated by the mycelium growth rate method. The in vitro antifungal bioassays indicated that most of compounds displayed excellent and broad-spectrum antifungal activities. Especially, compounds 6-chloro-3-phenylimidazo[1,2-b]pyridazine, 6-chloro-3-(2-fluorophenyl)imidazo[1,2-b]pyridazine, 6-chloro-3-(2-chlorophenyl)imidazo[1,2-b]pyridazine, 6-chloro-3-(thiophen-3-yl)imidazo[1,2-b]pyridazine and 6-methoxy-3-phenylimidazo[1,2-b]pyridazine exhibited 1.9-25.5 fold more potent than the com. available fungicide hymexazol against Corn Curvalaria Leaf Spot (CL), Alternaria alternate (AA), Pyricularia oryzae (PO) and Alternaria brassicae (AB) strains. Structure-activity relation anal. showed that the enhanced antifungal activity is significantly affected by the substituents on the benzene ring and pyridazine ring.

Bioorganic & Medicinal Chemistry Letters published new progress about 622-40-2. 622-40-2 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Alcohol, name is 2-Morpholinoethanol, and the molecular formula is C6H13NO2, Safety of 2-Morpholinoethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yu, Wan-Lei published the artcileDehydrogenative Silylation of Alkenes for the Synthesis of Substituted Allylsilanes by Photoredox, Hydrogen-Atom Transfer, and Cobalt Catalysis, Computed Properties of 20880-92-6, the publication is Angewandte Chemie, International Edition (2019), 58(32), 10941-10945, database is CAplus and MEDLINE.

A synergistic catalytic method combining photoredox catalysis, hydrogen-atom transfer, and proton-reduction catalysis for the dehydrogenative silylation of alkenes was developed. With this approach, a highly concise route to substituted allylsilanes has been achieved under very mild reaction conditions without using oxidants. This transformation features good to excellent yields, operational simplicity, and high atom economy. Based on control experiments, a possible reaction mechanism is proposed.

Angewandte Chemie, International Edition published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C18H16N2O6, Computed Properties of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Liang published the artcileMetal- and solvent-free conditions for the acylation reaction catalyzed by carbon tetrabromide (CBr₄), Computed Properties of 27292-49-5, the publication is Green Chemistry (2007), 9(9), 1022-1025, database is CAplus.

An efficient and useful catalyst, carbon tetrabromide (CBr₄), was discovered to be highly effective for the acylation of phenols, alcs., and thiols under metal- and solvent-free conditions.

Green Chemistry published new progress about 27292-49-5. 27292-49-5 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Benzene,Phenol, name is 3-Morpholinophenol, and the molecular formula is C9H6F3NO, Computed Properties of 27292-49-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liang, YaoYao published the artcileDirected evolution of PobR allosteric transcription factor to generate biosensor for 4-hydroxymandelic acid, Formula: C8H8O3, the publication is World Journal of Microbiology & Biotechnology (2022), 38(6), 104, database is CAplus and MEDLINE.

Hydroxy-mandelic acid (HMA) is widely applied in pharmaceuticals, food and cosmetics. In this study, we aimed to develop an allosteric transcription factors (aTFs) based biosensor for HMA. PobR, an aTF for HMA analog 4-hydroxybenzoic acid, was used to alter its selectivity and create novel aTFs responsive to HMA by directed evolution. We established a PobR mutant library with a capacity of 550,000 mutants using error-prone PCR and Megawhop PCR. Through our screening, two mutants were obtained with responsiveness to HMA. Anal. of each missense mutation indicating residues 122-126 were involved in its PobR ligand specificity. These results showed the effectiveness of directed evolution in switching the ligand specificity of a biosensor and improving HMA production

World Journal of Microbiology & Biotechnology published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Formula: C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yang, Zhi published the artcileEfficient hydrodeoxygenation of phenolic compounds and raw lignin-oil under a temperature-controlled phase-transfer catalysis, Formula: C9H12O, the publication is Fuel (2021), 120091, database is CAplus.

An effective binary catalyst by using tungstic acid (H₂WO₄) and Ru/C was employed for the hydrodeoxygenation (HDO) of phenolic compounds and raw lignin-oil. H2WO4 was presented as solid at ambient temperature, but it dissolved at high temperature above 100°C and therefore functioned as an active homogeneous catalyst. This phenomenon resulted in a temperature-controlled phase-transfer behavior in the HDO of phenolic compounds An efficient HDO performance and an exceptional reusability for guaiacol HDO were presented by this bifunctional catalyst, which can be reused more than 10 times with guaiacol conversion and cyclohexane selectivity over 90%. The comparison of traditional liquid organic and mineral acids, as well as solid acids, with H₂WO₄ confirmed the outstanding catalytic performance of H₂WO₄ and highlighted the advantages of H₂WO₄ as a homogeneous catalyst. Besides guaiacol, other phenolic compounds including various monomers and dimers all exhibited good HDO results, with 100% conversion and cycloalkanes selectivity. Moreover, the raw lignin-oil can be efficiently deoxygenated under the catalysis of this bifunctional catalyst 99.3% content of hydrocarbons was obtained in the upgraded lignin-oil, which was promising to be used as fuel directly. This catalytic system has great potential for the industrial application of lignin-oil upgrade.

Fuel published new progress about 645-56-7. 645-56-7 belongs to alcohols-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 4-Propylphenol, and the molecular formula is C15H12O6, Formula: C9H12O.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kautny, Paul published the artcileOxadiazole based bipolar host materials employing planarized triarylamine donors for RGB PHOLEDs with low efficiency roll-off, Safety of 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, the publication is Journal of Materials Chemistry C: Materials for Optical and Electronic Devices (2014), 2(11), 2069-2081, database is CAplus.

6 Novel triarylamine-containing oxadiazole compounds (o-PCzPOXD, o-ICzPOXD, o-TPATOXD, o-PCzTOXD, o-ICzTOXD, o-CzTOXD) were designed, synthesized and characterized concerning applications as host materials in PHOLED devices. To further improve the ortho-linkage concept, the impact of incorporating planarized electron-donating triarylamine (TAA) structures on intramol. charge transfer was examined The effect was evaluated for 2 series of electron-accepting oxadiazole scaffolds, realizing ortho-linkage on the benzene (POXD) and the thiophene (TOXD) cores. Thermal anal. shows increased glass-transition temperatures for planarized structures indicating an improved morphol. stability. A higher degree of planarization also results in significantly increased singlet and triplet energy values, revealing the impact on the intramol. charge transfer. Using the developed materials, red (o-TPATOXD: CE_max: 28.8 cd A^-1, EQE_max: 16.9%), green (o-PCzPOXD: CE_max: 62.9 cd A^-1, EQE_max: 17.1%) and blue (o-PCzPOXD: CE_max: 29.8 cd A^-1, EQE_max: 13.4%) devices were achieved showing remarkably low efficiency roll-off for planarized donors. This is the 1st report of efficient blue devices for this specific class of host materials. Probably the results correlate with an increasing ortho-linkage effect and decreasing donor strength of the TAA moiety by planarization and, thus, tackling 1 of the major challenges in PHOLED research: improving both triplet energy and compound stability.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about 25240-59-9. 25240-59-9 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Boronic Acids,Boronate Esters, name is 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, and the molecular formula is C6H13BO3, Safety of 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xie, Yun published the artcileExcited-state hydroxide ion transfer from a model xanthenol photobase, Category: alcohols-buliding-blocks, the publication is Journal of Physical Chemistry B (2015), 119(6), 2498-2506, database is CAplus and MEDLINE.

This article reports a study of excited-state hydroxide ion release from a model xanthenol photobase, XanOH. The driving force for the reaction was tuned using solvent mixtures with varying water/acetonitrile ratios, and the kinetics of the reaction was monitored using ultrafast pump-probe spectroscopy. The intrinsic barrier for the heterolysis was evaluated using Marcus and bond-energy bond-order (BEBO) models. The obtained value (ΔG^#_o = 10.17-10.80 kcal/mol) is significantly higher than the intrinsic barriers found for the proton release from previously studied photoacids. These results were discussed in terms of the difference in structures of solvated H⁺ and OH^– ions.

Journal of Physical Chemistry B published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C9H10O3S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts