Author: tianli

Okimoto, Mitsuhiro published the artcileElectrooxidative cyclization of hydroxy amino compounds possessing a benzyl group, Name: 2-(Benzyl(methyl)amino)ethanol, the publication is Synthesis (2012), 44(9), 1315-1322, database is CAplus.

Several novel 2-aryl-1,3-oxazinane and 2-aryl-1,3-oxazolidine derivatives were synthesized from N-benzyl-2-piperidineethanols and N-benzyl-2-piperidinemethanols, resp., by using electrooxidative methods in methanol. For these reactions, the yields of the corresponding cyclized compounds were significantly increased by using catalytic amounts of iodide ions. In contrast, 3-dialkylamino-1-phenylpropanols afforded the expected cyclic 6-phenyl-1,3-oxazinane derivatives using only a small excess of base.

Synthesis published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Name: 2-(Benzyl(methyl)amino)ethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bonnet, Nelly published the artcileIonic strength mediated hydrophobic force switching of CF₃-terminated ethylene glycol self-assembled monolayers (SAMs) on gold, Quality Control of 2240-88-2, the publication is Chemical Communications (Cambridge, United Kingdom) (2007), 5066-5068, database is CAplus and MEDLINE.

We have synthesized oligo(ethylene glycol) CF₃-terminated switching self-assembled monolayers, which allow the force experienced by a hydrophobic object to be controlled via the ionic strength of the environment.

Chemical Communications (Cambridge, United Kingdom) published new progress about 2240-88-2. 2240-88-2 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol, name is 3,3,3-Trifluoropropan-1-ol, and the molecular formula is C3H5F3O, Quality Control of 2240-88-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Escobedo, Ericson published the artcileActivation of hydrogen peroxide, persulfate, and free chlorine by steel anode for treatment of municipal and livestock wastewater: Unravelling the role of oxidants speciation, Recommanded Product: 2-Methyl-3-bromo-2-butanol, the publication is Water Research (2022), 118305, database is CAplus and MEDLINE.

Despite the extensive application of electrochem. advanced oxidation processes (EAOPs) in wastewater treatment, the exact speciation of oxidants and their effects on pollutants removal efficiency, byproducts formation, and effluent toxicity are largely unknown. In this study, galvanostatic steel anodes were used to drive the electrochem. activation of hydrogen peroxide (EAHP), persulfate (EAP), and free chlorine (EAFC), for industrial-scale treatment of municipal and livestock wastewater with a focus on micropollutants and transformation products (MTPs) and effluent toxicity. Response surface methodol. determined the optimized conditions for each treatment towards total organic carbon ([TOC]₀ = 180 mg/L) removal at pH 3.0: persulfate dose = 0.12 mmol/min, 26.5 mA/cm²; free chlorine dose = 0.29 mmol/min, 37.4 mA/cm²; H₂O₂ dose = 0.20 mmol/min, 45 mA/cm². Probe-compound degradation revealed that HO^•, SO^•-₄ and Fe^IVO²⁺ species were simultaneously generated in EAP, whereas HO^• and Fe^IVO²⁺ were the principal oxidants in EAHP and EAFC, resp. Samples were analyzed via liquid and gas chromatog. in non-target screening (NTS) mode to monitor the generation or removal of MTPs and byproducts including compounds that have not been reported previously. The speciation of oxidants, shifted in presence of halide ions (Cl^–, Br^–) in real wastewater samples, significantly affected the mineralization efficiency and byproduct formation. The production of halogenated byproducts in EAFC and EAP substantially increased the effluent toxicity, whereas EAHP provided non-toxic effluent and the highest mineralization efficiency (75 – 80%) to be nominated as the best strategy.

Water Research published new progress about 2588-77-4. 2588-77-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 2-Methyl-3-bromo-2-butanol, and the molecular formula is C5H11BrO, Recommanded Product: 2-Methyl-3-bromo-2-butanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Hasegawa, Tadashi published the artcilePhotocyclization of (ω-dialkylamino)alkyl β-oxoesters via remote hydrogen transfer, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1990), 901-5, database is CAplus.

The (ω-dialkylamino)alkyl β-oxoesters PhCOCR₂CO₂(CH₂)_nN(CH₂R¹)CH₂R² I (n = 2, 3, 4; R = H, Me; R², R³ = H, Ph) undergo photocyclization via remote hydrogen transfer to give the medium-sized azalactones (II) and/or aminolactones III. Intramol. electron transfer from nitrogen to the excited carbonyl group of I occurs prior to the remote hydrogen transfer.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kinugawa, Masahiko published the artcileFacile synthesis of 1,4-dihydropyridine monocarboxylic acids and unsymmetrical dicarboxylates via quaternary ammonium salts of 2-aminoethyl 1,4-dihydropyridine-3,5-dicarboxylates, COA of Formula: C10H15NO, the publication is Synthetic Communications (1997), 27(19), 3321-3331, database is CAplus.

Useful 1,4-dihydropyridine unsym. dicarboxylates nitrendipine (I, R = Et), nicardipine (I, R = CH₂CH₂NMeCH₂Ph) and monocarboxylic acid I (R = H) were prepared from I (R = CH₂CH₂NMeCH₂Ph, N-benzyl-3-piperidinyl) via their quaternary ammonium salts, e.g., II.

Synthetic Communications published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, COA of Formula: C10H15NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Matejczyk, Marzena published the artcileThe study of biological activity of mandelic acid and its alkali metal salts in wastewaters, SDS of cas: 90-64-2, the publication is Environmental Research (2022), 112429, database is CAplus and MEDLINE.

In the present work we compared the biol. activity of mandelic acid (MA) and its Li, Na, K, Rb and Cs salts. The study also investigated the effect of raw wastewaters (RW) and treated wastewaters (TW), comparable to microbial medium (MM) on the biol. activity of the tested chem. compounds used in concentrations of 5; 2.5; 1.25; 0.625; 0.3125 mg/mL. In the present experiment the evaluation of the following parameters was performed: E. coli (ATCC 25922) cells viability, growth inhibition of E. coli (ATCC 25922), the inhibition of GFP protein, genotoxicity and ROS generation. Our results showed that three main factors differentiated the antibacterial activity of MA and its Li, Na, K, Rb and Cs salts: study environment (MM, RW, TW), metal forming salt of mandelic acid and concentration of tested compounds Addnl., raw and treated wastewater, compared to microbial medium, changes the antimicrobial activity of MA and its salts in relation to the E. coli strain. We also detected that both MA and its salts affect the GFP protein and the induction of the recA promoter (genotoxicity test). The activity of the tested salts in relation to these two parameters is strictly dependent on the type of salt-forming metal and the concentration used. The anal. of ROS synthesis suggests that in the majority of the studied mandelic acid salts, oxidative stress is the dominant mechanism of cytotoxicity and genotoxicity. We also showed that both raw wastewaters (RW) and treated wastewaters (TW), compared to microbial medium (MM), change significantly the activity of MA and its salts.

Environmental Research published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, SDS of cas: 90-64-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Adger, B. M. published the artcileCatalytic transfer hydrogenolysis of N-benzyl protecting groups, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol, the publication is Synthesis (1987), 53-5, database is CAplus.

The catalytic transfer hydrogenolysis of a number of N-benzyl compounds has been examined Of the three hydrogen donors studied, ammonium formate and hydrazine hydrate were more effective than sodium hypophosphite. In general, debenzylation of secondary and tertiary benzylamines could be readily accomplished by refluxing the substrate with an excess of the hydrogen donor in alc. solvents for a few hours using catalytic amounts of 10% palladium on carbon. The two N-benzyl heteroaromatic amines studied were stable to the above conditions.

Synthesis published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

O’Brien, Anne Marie published the artcileLocation of crosslinks in chemically stabilized horseradish peroxidase: implications for design of crosslinks, Related Products of alcohols-buliding-blocks, the publication is Biotechnology and Bioengineering (2001), 76(4), 277-284, database is CAplus and MEDLINE.

The bifunctional compound, ethylene-glycol bis(N-hydroxysuccinimidylsuccinate) (EGNHS), stabilizes horseradish peroxidase C (HRP) by reaction with the enzyme’s lysine residues. In this study we compare native and modified HRP by proteolytic fragmentation, peptide sequencing, and mass spectroscopy, and identify the sites of modification. Most significantly, EGNHS is shown to form a crosslink between Lys232 and Lys241 of HRP and modifies Lys174 without formation of a crosslink. These findings are in agreement with the lysine side-chain reactivities predicted from the surface accessibility of the amino groups, and the maximal span of 16 Å of the EGNHS crosslinker.

Biotechnology and Bioengineering published new progress about 70539-42-3. 70539-42-3 belongs to alcohols-buliding-blocks, auxiliary class pyrrolidine,Ester,Amide,Inhibitor,Inhibitor, name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, and the molecular formula is C18H20N2O12, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

O’Brien, Anne Marie published the artcileDye bleaching and phenol precipitation by phthalic anhydride-modified horseradish peroxidase, Name: Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, the publication is Journal of Chemical Technology & Biotechnology (2000), 75(5), 363-368, database is CAplus.

The phenol precipitation and dye bleaching capabilities of phthalic anhydride-modified horseradish peroxidase C (PA-HRP) were compared with those of native HRP C and ethylene glycol bis(succinic acid N-hydroxysuccinimide ester)-modified HRP (EG-HRP) reported previously. The removal efficiency (percentage of phenol removed from solution under exptl. conditions) was determined for native HRP and both modified forms. Removal efficiencies at 37° were very similar, with >95% removal in each case. Removal efficiencies were less at 70° overall (range 25-45%), but PA-and EG-HRP removed up to 50% more phenol than native HRP. The three HRP forms showed similar dye bleaching performance at 37° in the presence of H₂O₂ and accelerators (up to 86% color removal). PA- and EG-HRP showed slightly greater bleaching abilities at 65° than native HRP for some of the dye/accelerator combinations tested. Modified HRPs performed better in 40% (volume/volume) mixtures of dioxane or DMF.

Journal of Chemical Technology & Biotechnology published new progress about 70539-42-3. 70539-42-3 belongs to alcohols-buliding-blocks, auxiliary class pyrrolidine,Ester,Amide,Inhibitor,Inhibitor, name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, and the molecular formula is C18H20N2O12, Name: Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Colleary, Sandra published the artcileStability and catalytic properties of chemically modified pig trypsin, Related Products of alcohols-buliding-blocks, the publication is Biocatalysis and Biotransformation (2009), 27(5-6), 309-317, database is CAplus.

Pig trypsin was chem. modified with the bifunctional compound ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) to yield EG-trypsin. EG-trypsin showed greater thermal stability (100% active beyond 100 min at 55°C; native only 53% active at 100 min) together with slightly increased tolerance toward some organic solvents. Arg/Lys hydrolysis ratio changed little. Esterase/amidase activity ratio of EG-trypsin in buffer was 11-fold greater than that of native pig trypsin, but 5-fold less in 30% volume/volume acetonitrile. In buffer, EG-trypsin synthesized the dipeptide benzoyl-Arg-Leu-NH₂ at a 3-fold higher rate than native trypsin, but native trypsin outperformed EG-trypsin in 30% volume/volume acetonitrile.

Biocatalysis and Biotransformation published new progress about 70539-42-3. 70539-42-3 belongs to alcohols-buliding-blocks, auxiliary class pyrrolidine,Ester,Amide,Inhibitor,Inhibitor, name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, and the molecular formula is C18H20N2O12, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts