Author: tianli

Bojinova, S published the artcile[The use of prostaglandin F2alpha (Prostin 15M) for terminationof second trimester pregnancy]., Safety of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, the publication is Akusherstvo i ginekologiia (2013), 52(2), 53-5, database is MEDLINE.

The authors describe a case of terminating a second trimester pregnancy in 21 gestational weeks with use of Prostin 15 M. The patient come to the clinic in 21 gestational week with spontaneous rupture of the liquid amnii 72 hours ago, without any contractions and cervical dilatation. The foetus has breech presentation. From the ultrasound investment the fetal weight is measured to be around 380 grams and it has been confirmed that the liquid is less than normal. The woman refuse the use of Foley catheter. We induce the delivery with 10 E Oxytocin intravenously and with Cytotec by vaginal and per oral way (3 tablets equal to 600 micrograms) but there was no effect. There were no changes at the cervix and no contractions. Then we use 4 ampules of Prostin 15 M intramuscular through three hours and the pregnancy was successfully terminated.

Akusherstvo i ginekologiia published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Safety of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chainet, Fabien published the artcileCombining Fourier Transform-Ion Cyclotron Resonance/Mass Spectrometry Analysis and Kendrick Plots for Silicon Speciation and Molecular Characterization in Petroleum Products at Trace Levels, Product Details of C6H16OSi, the publication is Analytical Chemistry (Washington, DC, United States) (2012), 84(9), 3998-4005, database is CAplus and MEDLINE.

A new method combining FT-ICR/MS anal. and Kendrick plots for the characterization of silicon species at trace levels in light petroleum products is presented. The method provides efficient instrumental detection limits ranging from 80 ng/kg to 5 μg/kg and reliable mass accuracy lower than 0.50 ppm for model silicon mols. in spiked gasoline. More than 3000 peaks could be detected in the m/z 50-500 range depending on the nature of the gasoline sample analyzed. An inhouse software program was used to calculate Kendrick plots. Then, an algorithm searched, selected, and represented silicon species classes (O₂Si, O₃Si, and O₄Si classes) in Kendrick plots by incorporating model mols.’ information (i.e., exact mass and intensity). This procedure allowed the complete characterization of more than 50 new silicon species with different degrees of unsaturation in petroleum products.

Analytical Chemistry (Washington, DC, United States) published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C6H16OSi, Product Details of C6H16OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Igielska-Kalwat, Joanna published the artcileThe use of Dalmatian pyrethrum daisy and an excipient in the treatment of seborrheic dermatitis, Synthetic Route of 90-64-2, the publication is Acta Biochimica Polonica (2022), 69(1), 123-129, database is CAplus and MEDLINE.

The active ingredients of the Pyretrin-D trichol. cosmetic series, namely benzyl benzoate, Dalmatian pyrethrum daisy, Cistus incanus, tea tree oil and geranium oil, almond acid and arginine were tested in respect to the treatment of seborrheic dermatitis. The paper describes the application of Dalmatian pyrethrum daisy and the excipient. Methods and devices used to confirm the effectiveness of the tested formulations included the TrichoScope Polarizer Dino-Lite (MEDL4HM) and the scanning electron microscope (SEM).

Acta Biochimica Polonica published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Synthetic Route of 90-64-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barret, Laurie-Anne published the artcileA new high-performance thin layer chromatography-based assay of detergents and surfactants commonly used in membrane protein studies, Application of (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol, the publication is Journal of Chromatography A (2013), 135-141, database is CAplus and MEDLINE.

The hydrophobic nature of membrane proteins (MPs) necessitates the use of detergents for their extraction, solubilization and purification Because the concentration of amphiphiles is crucial in the crystallization process, detergent quantification is essential to routine anal. Here we describe a quant. high-performance thin-layer chromatog. (HPTLC) method we developed for the detection of small quantities of detergent bound to solubilized MPs. After optimization of aqueous deposit conditions, we show that most detergents widely used in membrane protein crystallog. display distinctive mobilities in a mixture of dichloromethane, methanol and acetic acid 32:7.6:0.4 (volume/volume/v). Migration and derivatization conditions were optimized with n-dodecyl-β-D-maltoside (DDM), the most popular detergent for membrane protein crystallization A linear calibration curve very well fits our data from 0.1 to 1.6 μg of DDM in water with a limit of detection of 0.05 μg. This limit of detection is the best achieved to date for a routine detergent assay, being not modified by the addition of NaCl, commonly used in protein buffers. With these chromatog. conditions, no prior treatment is required to assess the quantities of detergent bound to purified MPs, thus enabling the quantification of close structure detergents via a single procedure. This HPTLC method, which is fast and requires low sample volume, is fully suitable for routine measurements.

Journal of Chromatography A published new progress about 85618-21-9. 85618-21-9 belongs to alcohols-buliding-blocks, auxiliary class Tetrahydropyran,Chiral,sulfides,Alcohol, name is (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C14H28O5S, Application of (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Coupek, Jiri published the artcileGel chromatographic behavior of mononuclear aromatic hydrocarbons and phenols, Formula: C14H22O2, the publication is Journal of Chromatography (1974), 95(1), 103-12, database is CAplus.

The gel chromatog. behavior of aromatic hydrocarbons and phenols during elution with THF in columns packed with styrene-divinylbenzene copolymer was investigated. From the elution volumes of 27 aromatic hydrocarbons and 80 phenols, conclusions were drawn about the effects of the types and positions of substituents and of the numbers and positions of phenolic hydroxyl groups on the elution volumes of these compounds in the system under investigation. The effects of the size of the alkyl substituents and of their positions with respect to the hydroxyl group of phenols were determined, and the partial contributions of the alkyl and hydroxyl groups to the elution volumes were calculated Chromatog. results were used for the characterization of the solvatability of phenolic mols. with THF and as the basis of a discussion of problems of the steric hindrance of hydroxyl groups due to neighboring substituents.

Journal of Chromatography published new progress about 1139-46-4. 1139-46-4 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, and the molecular formula is C14H22O2, Formula: C14H22O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pospisil, J. published the artcileThe influence of the structure on the activity of hydroquinone-type fat antioxidants, Application of 2,5-Bis(2,4,4-trimethylpentan-2-yl)benzene-1,4-diol, the publication is Fette, Seifen, Anstrichmittel (1964), 66(12), 1043-7, database is CAplus.

The antioxidant activity of hydroquinone (I) was compared with that of 43 I derivatives The neg. effect of 2,5- and 2,6-substitution was confirmed. Increased activity is found with 2-alkyl I derivatives, with 2,6-di-tert-Bu I derivatives in which the 4-OH group is etherified or acetylated, and with 2-tert-Bu- and 2-tert-octyl-4-methoxyphenols.

Fette, Seifen, Anstrichmittel published new progress about 903-19-5. 903-19-5 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 2,5-Bis(2,4,4-trimethylpentan-2-yl)benzene-1,4-diol, and the molecular formula is C22H38O2, Application of 2,5-Bis(2,4,4-trimethylpentan-2-yl)benzene-1,4-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Pospisil, J. published the artcileAntioxidants and stabilizers. XIII. Activity of phenolic antioxidants with large tertiary alkyl groups in lard and isopropyl oleate, Safety of 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, the publication is Fette, Seifen, Anstrichmittel (1968), 70(6), 442-5, database is CAplus.

The activity of 5 types of phenolic antioxidants containing 1 or 2 OH groups and substituted by 1 or more large tert-alkyl groups with 4, 8, or 12 C atoms was tested with lard and iso-Pr oleate as substrates. The effectiveness of the antioxidants was dependent on several factors which affect their reaction with the ROO- radicals formed by the autoxidation of the fat. The antioxidants tested had a different effect on the 2 substrates. The best effect was with a 2,4,6-trisubstituted phenol and a 4-tert-alkylpyrocatechol acting on lard. 17 references.

Fette, Seifen, Anstrichmittel published new progress about 1139-46-4. 1139-46-4 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, and the molecular formula is C14H22O2, Safety of 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yap, Chew Pheng published the artcileMetal-free catalytic hydrogen production from a polymethylhydrosilane-water mixture, Safety of Triethylsilanol, the publication is RSC Advances (2016), 6(7), 5903-5906, database is CAplus.

Hydrogen gas is the most promising carbon-free energy carrier although its on-demand generation remains a formidable challenge. One of the potential pathways for generating hydrogen is through hydrolytic oxidation of organosilanes. Here, we demonstrate that the hydroxide ion OH^– serves as a potent room-temperature metal-free catalyst in the hydrolytic oxidation of polymethylhydrosilane, PMHS to hydrogen gas and the corresponding silanol with a turnover number and turnover frequency in excess of 200 and 8 min^-1 resp. Kinetic studies suggest the hydrogen generation rate is first order with respect to PMHS and OH^– but zero order with respect to water. The first step of the reaction, where the Si center of PMHS is attacked by the OH^– ion, is believed to be the rate-determining step.

RSC Advances published new progress about 597-52-4. 597-52-4 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is Triethylsilanol, and the molecular formula is C7H7ClN2S, Safety of Triethylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yap, Chew Pheng published the artcileMetal-free catalytic hydrogen production from a polymethylhydrosilane-water mixture, Quality Control of 17877-23-5, the publication is RSC Advances (2016), 6(7), 5903-5906, database is CAplus.

Hydrogen gas is the most promising carbon-free energy carrier although its on-demand generation remains a formidable challenge. One of the potential pathways for generating hydrogen is through hydrolytic oxidation of organosilanes. Here, we demonstrate that the hydroxide ion OH^– serves as a potent room-temperature metal-free catalyst in the hydrolytic oxidation of polymethylhydrosilane, PMHS to hydrogen gas and the corresponding silanol with a turnover number and turnover frequency in excess of 200 and 8 min^-1 resp. Kinetic studies suggest the hydrogen generation rate is first order with respect to PMHS and OH^– but zero order with respect to water. The first step of the reaction, where the Si center of PMHS is attacked by the OH^– ion, is believed to be the rate-determining step.

RSC Advances published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C12H25Br, Quality Control of 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Jingyao published the artcileChIA-PET analysis of transcriptional chromatin interactions, Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, the publication is Methods (Amsterdam, Netherlands) (2012), 58(3), 289-299, database is CAplus and MEDLINE.

Long-range chromatin contacts between specific DNA regulatory elements play a pivotal role in gene expression regulation, and a global characterization of these interactions in the 3-dimensional (3D) chromatin structure is imperative in understanding signaling networks and cell states. Chromatin Interaction Anal. using Paired-End Tag sequencing (ChIA-PET) is a method which converts functional chromatin structure into millions of short tag sequences. Combining Chromatin Immunoprecipitation (ChIP), proximity ligation and high-throughput sequencing, ChIA-PET provides a global and unbiased interrogation of higher-order chromatin structures associated with specific protein factors. Here, we describe the detailed procedures of the ChIA-PET methodol., unraveling transcription-associated chromatin contacts in a model human cell line.

Methods (Amsterdam, Netherlands) published new progress about 70539-42-3. 70539-42-3 belongs to alcohols-buliding-blocks, auxiliary class pyrrolidine,Ester,Amide,Inhibitor,Inhibitor, name is Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate, and the molecular formula is C20H19NO4, Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) O,O’-ethane-1,2-diyl disuccinate.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts