Author: tianli

Sajjad, Hussnain published the artcileDegradable polyanhydride networks derived from itaconic acid, Name: Pentaerythritol tetra(3-mercaptopropionate), the main research area is itaconic acid polyanhydride thiol ene photopolymerization thermomech viscoelastic property.

The development of tunable and degradable crosslinked-polyanhydride networks from renewably derived itaconic anhydrides and multifunctional thiols is presented. Itaconic acid was initially converted to Et itaconic anhydride and isoamyl itaconic anhydride via a two-step synthetic procedure on hundred-gram scale with minimal purification Dinorbornene-functionalized derivatives were prepared via cycloaddition chem., and photoinitiated thiol-ene polymerization reactions were explored using com. available tetra- and hexa-functional thiols, all using solvent-free syntheses. The thiol-ene reaction kinetics of different monomer compositions were characterized by real-time Fourier transform IR (RT-FTIR) spectroscopy, with the norbornene functionalized derivatives exhibiting the highest reactivity towards thiol-ene photopolymerizations The thermal and mech. characteristics of the thermosets were analyzed and the viscoelastic behavior was investigated by dynamic mech. anal. to understand the influence of the ester functionality and choice of crosslinker on the material properties. The anhydride backbone was found to be susceptible to controlled degradation under physiol.-(phosphate-buffered saline) and environmentally-relevant (artificial seawater) testing conditions over a period of 60 days at 50°C. This work demonstrates that itaconic acid may be a useful feedstock in the generation of degradable polyanhydride networks via thiol-ene photopolymerization

Polymer Chemistry published new progress about Acid hydrolysis. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Name: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wandee, Yuree published the artcileYield and structural composition of pomelo peel pectins extracted under acidic and alkaline conditions, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is pomelo peel pectin yield structural composition acidic alk.

Extraction of pectin from pomelo peel was performed using water, acid and alk. solutions with a microwave power of 1100 W for 2 min, and yield and structural/chem. characteristics of the extracted pectins were investigated. Extraction of pectin with water gave the lowest yield (6.5%, dry weight basis). The water-extracted pectin contained the highest amount of neutral sugar (29.5%), while equivalent mol. weight (MWeq) and degree of methylation (DM) were 43 kDa and 29.7%, resp. Extraction of pectin with HCl solutions at concentrations of 25, 50, 100 and 200 mM resulted in a significant increase of pectin yields (12.1-20.5%) and pectins with high amount of galacturonic acid (83.3-85.6%). The MWeq and DM of the acid-extracted pectins ranged from 171 to 368 kDa and 53.9-82.5%, resp. Compared to the acid, extraction with NaOH solutions at the same concentrations provided higher yields (13.9-24.2%), smaller size (142-187 kDa) and lower DM (<1.7%) pectins, while amount of galacturonic acid was comparable. The highest yield of extraction was found at a concentration of 50 mM for both HCl and NaOH solutions Extraction of pomelo peel with 50 mM NaOH solution by reduction of the microwave power to 550 W and extending the extraction time to 15 min resulted in an increase of pectin yield (29.2%) and pectin with smaller size (76 kDa). Food Hydrocolloids published new progress about Acid hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pierre, Ronan published the artcileCarboxymethyl glucosides and carboxymethyl glucoside lactones: A detailed study of their preparation by oxidative degradation of disaccharides, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is acid hydrolysis isomaltulose oxidation catalysis glucoside preparation; carboxymethyl glucoside lactone preparation oxidative degradation disaccharide synthon.

A detailed study of the access to carboxylmethyl tri-O-acetyl-α-D-glucopyranoside 2-O-lactone from isomaltulose was performed. Side products can arise from incomplete oxidation of isomaltulose by hydrogen peroxide, acidic hydrolysis, or opening of the lactone during the acylation step. Based on these observations, the optimum conditions for the preparation of this interesting synthon, as well as of its benzylated and pivaloylated analogs, was determined Also, the use of the hydrogenated analog of isomaltulose, isomalt, as the starting material was studied. In this case, during the oxidation step, the catalysis by sodium tungstate proved to be indispensable to form carboxymethyl glucoside, unlike for isomaltulose. Although giving low yields, this reaction is very direct and was performed using cheap and simple procedures from a readily available substrate.

Comptes Rendus Chimie published new progress about Acid hydrolysis. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

El-Masry, Amal A. published the artcileEco-friendly green liquid chromatographic determination of azelastine in the presence of its degradation products: applications to degradation kinetics, Computed Properties of 111-87-5, the main research area is azelastine hydrochloride microemulsion liquid chromatog degradation kinetics.

Background: Green solvents such as microemulsion were used in the proposed method because they play a vital role in the anal. method’s influence on the environment. Objective: A highly sensitive, specific, and validated stability-indicating eco-friendly green microemulsion liquid chromatog. (MELC) method was developed for separation of the antihistaminic drug Azelastine HCl (AZL) from its degradation products with application to degradation kinetics. Methods: Chromatog. separation was operated on a C18 column with a microemulsion mobile phase, which consists of 0.1 M sodium dodecyl sulfate, 10% n-propanol, 1% n-octanol, and 0.3% triethylamine, by using 0.02 M phosphoric acid at pH 3.5 and irbesartan as internal standard The eluted compounds were monitored at 210 nm with flow rate 1 mL/min at ambient temperature Results: A linear dependence of the peak area on drug concentration over the concentration range of 0.1 to 25 μg/mL was achieved with an LOD of 0.04 μg/mL and an LOQ of 0.10 μg/mL. Moreover, the proposed method was successfully applied for determination of AZL in eye drops and metered dose nasal inhaler as well as to study the kinetics of alk., acidic, neutral, oxidative, and photolytic degradation processes of AZL according to the International Council for Harmonization guidelines. Conclusions: The proposed method could be used as a harmless alternative for quality control anal. of the mentioned drug, without interference from dosage form additives or decomposition products. Highlights: A highly sensitive stability-indicating eco-friendly green MELC method was developed for the separation of the antihistaminic drug AZL from its degradation products.

Journal of AOAC International published new progress about Acid hydrolysis. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Computed Properties of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jia, Yanan published the artcileThe structural characteristic of acidic-hydrolyzed corn silk polysaccharides and its protection on the H2O2-injured intestinal epithelial cells, Application In Synthesis of 59-23-4, the main research area is corn silk polysaccharide acidic hydrolysis hydrogen peroxidase cell injury; Acidic-hydrolyzation; Antioxidant activity; Corn silk polysaccharides; Intestinal epithelial cells.

This work aims to describe the purification and characterization of acidic-hydrolyzed corn silk polysaccharides (AH-CSP) and evaluate their protection on the H2O2-injured intestinalepithelial cells (IEC-6). Two fractions named AHP-1 and AHP-2 were obtained from AH-CSP, and physicochem. properties of them were investigated by gel permeation chromatog. (GPC), gas chromatog. (GC), NMR (NMR), fourier transform IR (FT-IR) spectroscopy, scanning electronic microscopy (SEM), and Congo red test. Results showed that AHP-1 (2.80 x 104 Da) and AHP-2 (1.25 x 104 Da) were consisted of xylose, mannose, galactose, rhamnose, arabinose, and glucose. AHP-1 and AHP-2 had strong scavenging activities on 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-Azobis-3-ethylbenzthiazoline-6-sulfonic acid (ABTS), and OH· free radicals. Furthermore, pretreatment with AHP-2 could protect the H2O2-injured IEC-6 cells by effectively scavenging the overproduced reactive oxygen species (ROS) and regulating of Kelch-like ECH-associated protein 1(Keap1)/ nuclear factor erythroid 2-related factor 2 (Nrf2) signal pathway.

Food Chemistry published new progress about Acid hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Jixian published the artcileEffects of subcritical water extraction microenvironment on the structure and biological activities of polysaccharides from Lentinus edodes, SDS of cas: 59-23-4, the main research area is Lentinus polysaccharide structure subcritical water extraction microenvironment antioxidant antitumor; Biological activities; Microenvironment; Polysaccharides; Structure; Subcritical water.

In the present study, we investigated the effects of subcritical water microenvironment on the structure and biol. activities of polysaccharides from Lentinus edodes. The results showed that, under different SWE conditions (100-150°C for 15 min, and 150°C for 10-30 min), all the polysaccharides were heteropolysaccharides and consisted of glucose, mannose and galactose with different molar ratios. In addition, FT-IR results showed that all samples were typical β-pyranose and protein-free polysaccharides. Moreover, Congo red staining and at. force microscope (AFM) analyses showed that when the temperature was above 150°C for 15 min, the triple-helix structure no longer existed. Furthermore, various polysaccharides had varying degrees of inhibitory effect on HepG2 cells and MCF-7 cells in vitro. These findings indicated that subcritical water microenvironment has an extremely important effect on the structure and bioactivities of polysaccharides. The polysaccharides may be extracted more effectively by changing the subcritical water microenvironment.

International Journal of Biological Macromolecules published new progress about Acid hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, SDS of cas: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Xiao published the artcileCharacterization of free and glycosidically bound volatile compounds from tamarillo (Solanum betaceum Cav.) with considerations on hydrolysis strategies and incubation time, Recommanded Product: 3-Pentanol, the main research area is Solanum enzyme hydrolysis glycoside volatile compound prenol.

Two different hydrolysis strategies, namely acid hydrolysis (pH 0 and 3) and enzyme hydrolysis (Rapidase AR2000, β-glucosidase, 5.6 nkat/mg), and the effect of hydrolysis time on the liberation of glycosidically bound volatiles from tamarillo (Solanum beaceum Cav.), were evaluated. Free and bound volatile profiles in tamarillo were also compared. Enzymic hydrolysis was favored for the liberation of aldehydes, esters, and terpenes. Harsh acidic hydrolysis (pH 0) was particularly effective at releasing C13-norisoprenoids including 3-hydroxy-β-damascone and 1,1,6-trimethyl-1,2-dihydronaphthalene (TDN), but those compounds cannot contribute to the pleasant odor. Moreover, the longer the duration of enzymic hydrolysis, the higher was the concentration of alcs., terpenes, benzenoids, ketones, and volatile phenols. On the other hand, 33 free and 49 bound volatiles were identified in tamarillo with a complementary profile: the major free volatiles were alcs. ((Z)-3-hexenol, 1-hexanol) and esters (Me caproate, Me butanoate and Et butanoate), while bound volatile compounds showed higher concentrations of benzenoids (benzyl alc. and phenylethyl alc.) and terpenes, including prenol, linalool and α-terpineol. Many glycosidically bound volatiles are available as aroma reservoirs in tamarillo, and to liberate these compounds during tamarillo-based product development, attention should be given to hydrolysis strategies and incubation time.

LWT–Food Science and Technology published new progress about Acid hydrolysis. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Recommanded Product: 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Salomon, Lysanne published the artcileComparison of the phenolic compound profile and antioxidant potential of Achillea atrata L. and Achillea millefolium L, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is phenolic compound antioxidant Achillea atrata millefolium; Achillea atrata L.; Achillea millefolium L.; DPPH; antioxidant activity; phenolic metabolome.

In the present study, Achillea atrata L. and A. millefolium L. were compared for the first time with regard to their phenolic compound profile and antioxidant activity by applying the 2,2-diphenyl-picryl hydrazyl radical assay. For this purpose, aerial plant parts were consecutively extracted with solvents of increasing polarity (dichloromethane, n-butanol, Et acetate), revealing that the A. atrata Et acetate fraction showed the highest antioxidant activity with an IC50 value of 12.2 ±0.29 μg/mL compared to 17.0 ± 0.26 μg/mL for A. millefolium. Both species revealed the presence of luteolin, apigenin, centaureidin, and nevadensin exclusively in this most polar fraction, which are known as effective 2,2-diphenyl-picryl hydrazyl radical scavengers. The antioxidant capacity of the aforementioned fractions strikingly correlated with their total phenolic contents, which was highest in the Et acetate fraction of A. atrata. Characterization of the metabolite profiles of both Achillea species showed only marginal differences in the presence of key compounds, whereas the concentrations of individual compounds appeared to be species-specific. Our results suggest that A. atrata, based on its compound pattern and bioactivity characteristics, has similar qualities for phytotherapy as A. millefolium.

Molecules published new progress about Achillea atrata. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Safety of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ren, Qing published the artcileThe changes of microbial community and flavor compound in the fermentation process of Chinese rice wine using Fagopyrum tataricum grain as feedstock, Quality Control of 505-10-2, the main research area is microbial community flavor compound Fagopyrum Chinese rice wine fermentation.

Chinese rice wine (CRW), a unique wine species, has a long history in China. Fagopyrum tataricum grain is a kind of high-quality grain with function in health care. The production of CRW wine with F. tataricum grain is beneficial to the development of new rice wine products. The flavor compounds and microorganisms in F. tataricum grain rice wine were studied. One hundred and seven volatile compounds (including 11 kinds of pyrazines that were rarely detected in wine) were detected and eight organic acids were measured. The microecol. diversity in the fermentation process of F. tataricum rice wine was studied. It was found that Bacillus was the main bacterial genus, and the unclassfied_O_Saccharomycetales was the main fungi. Correlation anal. between microorganism and flavor compound shown there are 838 correlations. A total of 108 microbial genera maybe participate in the formation of flavor compounds In addition, fourteen genera included unclassified_O_Saccharomycetales, Lactococcus, Pediococcus, Aspergillus, Cladosporium, Cochliobolus, Sporidiobolus, Pichia and Saccharomycopsis et al. were screened as functional significant microbiota and built correlation with flavor compounds This work provides a perspective for bridging the gap between flavor compound and microbial community, and advances our understanding of mechanisms in F. tataricum rice wine fermentation

Scientific Reports published new progress about Acetoanaerobium. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Quality Control of 505-10-2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Geffroy, Olivier published the artcileInvestigating the Aroma of Syrah Wines from the Northern Rhone Valley Using Supercritical CO2-Dearomatized Wine as a Matrix for Reconstitution Studies, Synthetic Route of 505-10-2, the main research area is supercritical dearomatized wine model aroma Syrah Rhone; Pivot profile; Syrah; aroma reconstitution; omission tests; supercritical CO2; wine.

This study aimed to investigate the key compounds involved in the aroma of French Syrah wines from the northern Rhone valley from two vintages characterized by distinct climatic conditions. The volatile composition of the wines was assessed through the determination of 76 mols. After identifying the best matrix and best model for aroma reconstitution studies, omission tests were conducted using the Pivot profile method. For both vintages, 35 mols. with odor activity values (OAVs) above 0.5 were identified. While remarkably high levels of 2-furfurylthiol (FFT) were reported in both wines, rotundone and 3-sulfanylhexanol (3SH) enabled the strongest discrimination between the two wines. Wine dearomatized using supercritical carbon dioxide (sCO2) was identified as the best matrix. The best models built using this matrix were composed of mols. with OAV > 5 and OAV > 10 highlighting that this dearomatization approach can be valuable to reconstitute the aroma of wine using a small number of mols. For the cool vintage wine, the omission of rotundone and FFT had the greatest impact on the olfactive profile for nonanosmic and anosmic respondents to rotundone, resp. 3SH, whose omission decreased the rating of the “”fruity”” attribute, was identified as the main contributor to the aroma of Syrah wine produced in the warm vintage.

Journal of Agricultural and Food Chemistry published new progress about Red wine (Syrah). 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Synthetic Route of 505-10-2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts