Author: tianli

Zhang, Ruilei published the artcileExcess molar enthalpies for binary mixtures of different amines with water, Computed Properties of 2212-32-0, the main research area is amine molar enthalpy binary mixture water.

The isothermal excess molar enthalpies for binary mixtures of different amines with water were measured with a C-80 Setaram calorimeter. The exptl. results indicate that the excess molar enthalpy is related to the mol. structure. The exptl. excess molar enthalpies were satisfactorily fitted with the Redlich-Kister equation. They were also used to test the suitability of the NRTL model, and the deviations are a little larger than the R-K equation.

Journal of Chemical Thermodynamics published new progress about Binary mixtures. 2212-32-0 belongs to class alcohols-buliding-blocks, name is N2-(2-Hydroxyethyl)-N1,N1,N2-trimethyl-1,2-ethylenediamine, and the molecular formula is C7H18N2O, Computed Properties of 2212-32-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yan-xiao published the artcilePreparation, characterization, and prebiotic activity of manno-oligosaccharides produced from cassia gum by a glycoside hydrolase family 134 β-mannanase, Synthetic Route of 59-23-4, the main research area is prebiotic mannooligosaccharide cassia gum mannanase; Cassia gum; Characterization; Manno-oligosaccharides; Prebiotic activity; β-Mannanase.

To produce mannooligosaccharides from cassia gum, a mutated glycoside hydrolase family 134 β-mannanase gene (mRmMan134A) from Rhizopus microsporus var. rhizopodiformis F518 was expressed in Pichia pastoris and a high expression level (3680 U mL-1) was obtained through high cell d. fermentation mRmMan134A exhibited maximum activity at pH 5.5 and 50°C. It was then subjected to hydrolyze cassia gum with 70.6% of overall yield of mannooligosaccharides. From the hydrolyzate, seven components (F1-F7) were separated and identified as mannose, mannobiose, galactose, mannotriose, mannotetraose, 61-α-D-galactosyl-β-D-mannobiose, and mannopentaose, resp. According to in vitro fermentation, the mannooligosaccharides were able to promote the growth of three Bifidobacterium strains and six Lactobacillus strains with 3.0-fold increment in culture absorbance, and these strains preferred mannooligosaccharides with DP 2-3 rather than those with DP 4-5. Novel mannooligosaccharides from cassia gum with promising prebiotic activity were provided in the present study.

Food Chemistry published new progress about Bifidobacterium. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Synthetic Route of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Schauber, Juergen published the artcileHuman rectal mucosal gene expression after consumption of digestible and non-digestible carbohydrates, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is rectum mucosa gene expression profile nutrition sucrose isomalt.

The effects of regular consumption of the low-digestible and prebiotic carbohydrate isomalt (Palatinit) vs. the digestible sucrose on gene expression in the rectal mucosa were examined in 19 healthy humans. They received 30 g isomalt or sucrose daily as part of controlled diet over two 4-wk test periods with a 4-wk washout in between. At the end of each test phase, rectal biopsies were obtained. After RNA extraction, mucosal gene expression was assayed using GeneChip microarrays. The expression of cathelicidin hCap18/LL37, cellular detoxification enzymes GSTπ, UGT1A1 and CYP3A4, cyclooxygenase 2, and barrier factors MUC2 and ZO-1 were determined by real-time RT-PCR. Microbiol. analyses of fecal samples revealed a shift of the gut flora to increased bifidobacteria counts following consumption of isomalt. Isomalt did not affect the rectal mucosal gene expression in microarray analyses compared to sucrose. The expression of cathelicidin LL37, GSTπ, UGT1A1, CYP3A4, COX-2, MUC2 and ZO-1 was not changed in rectal biopsies. Thus, gene expression of the human rectal mucosa can be reliably measured in biopsy samples taken at endoscopy. Dietary intervention with the low-digestible isomalt compared to sucrose did not affect the gene expression in the rectal mucosa.

Molecular Nutrition & Food Research published new progress about Bifidobacterium. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kalicka, Dorota published the artcilePhysical and sensory characteristics and probiotic survival in ice cream sweetened with various polyols, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is Bifidobacterium survival ice cream polyol sweetening agent probiotic.

The effect of polyols (xylitol, erythritol, maltitol and isomalt) on phys. and sensory properties of probiotic ice cream, as well as the survival of BifidobacteriumBB-12 during freezing over 28 days of frozen storage, was investigated. The control sample of ice cream, sweetened with sugar, showed a lower pH and higher overrun than those sweetened with polyols. The viable bifidobacteria counts remained above 8 log cfu/g in all samples. The amount of erythritol added was not enough to obtain a similar sweetness as in control, but too high to get an ice cream with good textural properties.

International Journal of Dairy Technology published new progress about Bifidobacterium. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zorrilla, Francisco published the artcileThe metaGEM: reconstruction of genome scale metabolic models directly from metagenomes, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is metaGEM genome scale metabolic model metagenome.

Metagenomic analyses of microbial communities have revealed a large degree of interspecies and intraspecies genetic diversity through the reconstruction of metagenome assembled genomes (MAGs). Yet, metabolic modeling efforts mainly rely on reference genomes as the starting point for reconstruction and simulation of genome scale metabolic models (GEMs), neglecting the immense intra- and interspecies diversity present in microbial communities. Here, we present metaGEM (https://github.com/ franciscozorrilla/metaGEM), an end-to-end pipeline enabling metabolic modeling of multi-species communities directly from metagenomes. The pipeline automates all steps from the extraction of contextspecific prokaryotic GEMs from MAGs to community level flux balance anal. (FBA) simulations. To demonstrate the capabilities of metaGEM, we analyzed 483 samples spanning lab culture, human gut, plant-associated, soil, and ocean metagenomes, reconstructing over 14,000 GEMs. We show that GEMs reconstructed from metagenomes have fully representedmetabolism comparable to isolated genomes. We demonstrate that metagenomic GEMs capture intraspecies metabolic diversity and identify potential differences in the progression of type 2 diabetes at the level of gut bacterial metabolic exchanges. Overall, metaGEM enables FBA-readymetabolic model reconstruction directly from metagenomes, provides a resource of metabolic models, and showcases community-level modeling of microbiomes associated with disease conditions allowing generation of mechanistic hypotheses.

Nucleic Acids Research published new progress about Bifidobacterium. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kansandee, Wiratchanee published the artcileCharacterization and Bifidobacterium sp. growth stimulation of exopolysaccharide produced by Enterococcus faecalis EJRM152 isolated from human breast milk, Product Details of C6H12O6, the main research area is Bifidobacterium exopolysaccharide Enterococcus breast milk; Bifidobacterium sp.; Exopolysaccharides; Human breast milk; Prebiotics.

Sixty lactic acid bacteria (LAB) isolated from human breast milk were screened for exopolysaccharides (EPS) production EPS characterization and Bifidobacterium sp. growth support were investigated. The highest EPS-producing isolate was EJRM152 which identified as Enterococcus faecalis (98% similarity) based on the 16S rDNA gene sequence. Product yield coefficient (YEPS/x) and EPS production were 3.68 and 4.32 g/l, resp. Crude EPS was purified by DEAE-cellulose and a Sephacryl S-400 column, and it revealed different mol. weights and molar ratios of glucose, galactose, rhamnose, arabinose and fructose. FT-IR spectroscopy of EPS showed functional groups including hydroxyl and carbonyl. B. animalis TISTR 2194, B. breve TISTR 2130, B. bifidum TISTR 2129, and B. longum TISTR 2195 grew well in media containing EPS, comparing with com. prebiotics. Results suggest that EPS produced by E. faecalis EJRM152 could be a potential candidate prebiotic.

Carbohydrate Polymers published new progress about Bifidobacterium. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Berglund, Jennie published the artcileThe structure of galactoglucomannan impacts the degradation under alkaline conditions, HPLC of Formula: 59-23-4, the main research area is galactoglucomannan degradation alk hydrolysis sugar mol dynamic simulation.

Galactoglucomannan (GGM) from spruce was studied with respect to the degradation behavior in alk. solution Three reference systems including galactomannan from locust bean gum, glucomannan from konjac and the linear water-soluble CM-cellulose were studied with focus on mol. weight, sugar composition, degradation products, as well as formed oligomers, to identify relative structural changes in GGM. Initially all mannan polysaccharides showed a fast decrease in the mol. weight, which became stable in the later stage. The degradation of the mannan polysaccharides could be described by a function corresponding to the sum of two first order reactions; one slow that was ascribed to peeling, and one fast that was connected with hydrolysis. The galactose side group was stable under conditions used in this study (150 min, 90°C, 0.5 M NaOH). This could suggest that, apart from the covalent connection to C6 in mannose, the galactose substitutions also interact non-covalently with the backbone to stabilize the structure against degradation Addnl., the combination of different backbone sugars seems to affect the stability of the polysaccharides. For CM-cellulose the degradation was linear over time which further suggests that the structure and sugar composition play an important role for the alk. degradation Mol. dynamics simulations gave details about the conformational behavior of GGM oligomers in water solution, as well as interaction between the oligomers and hydroxide ions.

Cellulose (Dordrecht, Netherlands) published new progress about Base hydrolysis. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, HPLC of Formula: 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chankaew, Chaiyos published the artcileKaffir lime leaf extract mediated synthesis, anticancer activities and antibacterial kinetics of Ag and Ag/AgCl nanoparticles, Formula: C10H20O2, the main research area is silver chloride nanoparticle kaffir lime leaf antibacterial kinetic property.

A facile phytosynthesis of Ag/AgCl and Ag nanoparticles (NPs) was developed using a crude water extract of Citrus hystrix DC (kaffir lime) leaves. The phytochem. and chloride contents of the extract, and various synthesis parameters were studied. The obtained Ag/AgCl and Ag NPs were of the cubic phase and mostly spherical in shape. Particle sizes of the yielded NPs were distributed in a narrow range with an average size of 20 and 38 nm for the Ag/AgCl and Ag NPs, resp. The reducing function of the phytochems. and the stabilizing ability of gelatin were demonstrated. The NPs showed significant anti-proliferative activities against the carcinoma HCT 116 and adenocarcinoma Caco-2 colorectal cell lines, but had a neg. effect toward human fibroblasts. The NPs exhibited excellent antibacterial activities against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus cereus. The inactivation kinetics obtained in the presence of the NPs showed a biphasic behavior that can be explained by the Cerf model.

Particuology published new progress about Bacillus cereus. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Formula: C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Niteeshkumar published the artcileChemical analysis and antibacterial activity of Black turmeric (Curcuma caesia Roxb.) genotypes, Synthetic Route of 124-76-5, the main research area is Curcuma Bacillus Streptococcus Pseudomonas Shigella.

Curcuma caesia Roxb. is an important, lesser known, non-conventional medicinal plant belonging to Zingiberaceae family. The eight genotypes selected were GKM-1, GKM-2, GKB-3, GKB-4, GKJ-5, GMV-6, GKT-29 and GKK-30 were collected from different regions as presented in (Table 1). The Rhizomes of black turmeric genotypes were extracted with methanol at room temperature for 18 h. Preliminary phytochem. anal. revealed the presence of tannins, flavonoid and phenol. The highest phenol GMV-6 (1.46 mg-1g), tannin GKT-29 (0.69 mg-1g) and flavonoid GMV-6 (1.64 mg-1g) was recorded. The bioactive compounds of Curcuma caesia Roxb have been evaluated using GC-MS. Totally 19 major compounds were identified from eight genotypes. The major constituents were identified in the methanolic rhizome extracts were Curcumenol in GKM-1(20.35%), GKB-3(12.96%), GKB-4(15.67%) and in GKT-29(16.17%), Curcumenone in GKM-1(16.07%), GKM-2(25.03%), GKB-3(29.30%) and in GKT-29(22.25%), Epicurzerenone in GKM-1(12.93%) and GKM-2(21.82%), 9-12, Octadecadionic acid in GKM-1(5.54%), GKB-3(2.81%) and in GKB-4(3.59%), 2-Bornanone in GKM-2(4.38%) and in GKB3(5.38%), 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl- in GKB-3(8.91%), GKB-4(24.44%), GKJ-5(19.82%) and GKT-29(9.88%), Isoborneol in GKM-2(1.54%) and GKB-3(3.67%) and Eucalyptol in GKM-2(1.17%). The research findings have shown that the rhizome of C. caesia is extensively rich in secondary metabolites. The extracts were assessed for their potential antibacterial activity against Gram pos. and Gram neg. bacteria viz., Bacillus cereus, Bacillus subtilis, Streptococcus agalactiae, Escherichia coli, Pseudomonas aeruginosa and Shigella flexneri. The rhizome extracts of black turmeric genotypes exhibit pos. results against the Gram pos. bacteria.

Pharma Innovation published new progress about Bacillus cereus. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Synthetic Route of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gerber, Lucie published the artcileImproved mitochondrial function in salmon (Salmo salar) following high temperature acclimation suggests that there are cracks in the proverbial ‘ceiling’, Application In Synthesis of 97-67-6, the main research area is reactive oxygen species oxidative stress energy metabolism Salmo.

Mitochondrial function can provide key insights into how fish will respond to climate change, due to its important role in heart performance, energy metabolism and oxidative stress. However, whether warm acclimation can maintain or improve the energetic status of the fish heart when exposed to short-term heat stress is not well understood. We acclimated Atlantic salmon, a highly aerobic eurythermal species, to 12 and 20°C, then measured cardiac mitochondrial functionality and integrity at 20°C and at 24, 26 and 28°C (this species’ critical thermal maximum ± 2°C). Acclimation to 20°C vs. 12°C enhanced many aspects of mitochondrial respiratory capacity and efficiency up to 24°C, and preserved outer mitochondrial membrane integrity up to 26°C. Further, reactive oxygen species (ROS) production was dramatically decreased at all temperatures These data suggest that salmon acclimated to ‘normal’ maximum summer temperatures are capable of surviving all but the most extreme ocean heat waves, and that there is no ‘tradeoff’ in heart mitochondrial function when Atlantic salmon are acclimated to high temperatures (i.e., increased oxidative phosphorylation does not result in heightened ROS production). This study suggests that fish species may show quite different acclimatory responses when exposed to prolonged high temperatures, and thus, susceptibility to climate warming.

Scientific Reports published new progress about Atlantic salmon. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Application In Synthesis of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts