Author: tianli

Hosseiny Davarani, Saied Saeed published the artcileQuantification of controlled release leuprolide and triptorelin in rabbit plasma using electromembrane extraction coupled with HPLC-UV, Formula: C8H18O, the main research area is HPLC UV plasma determination controlled release leuprolide triptorelin pharmacokinetics; electromembrane extraction HPLC controlled release leuprolide triptorelin; Electromembrane extraction; Leuprolide; Pharmacokinetic; Rabbit plasma; Triptorelin.

An electromembrane extraction followed by HPLC-UV technique was developed and validated for quantification of leuprolide and triptorelin in rabbit plasma. The influencing parameters on the extraction efficiency were optimized using exptl. design methodol. The optimized conditions were found to be; supported liquid membrane: a mixture of 1-octanol and 2-Et hexanol (1:1) containing 10% volume/volume di(2-ethylhexyl) phosphate, applied voltage: 5 V, extraction time: 5 min, pH of the donor phase: 4.5 and pH of the acceptor phase: 1.0. The optimized method was validated for linearity, intraday and interday precision, and accuracy in rabbit plasma. The range of quantification for both peptides was 0.5-1000 ng/mL with regression coefficients higher than 0.994. Relative recoveries of leuprolide and triptorelin were found to be 80.3 and 75.5%, resp. Limits of quantification and detection for both peptides were found to be 0.5 and 0.15 ng/mL, resp. The validated method was successfully applied to pharmacokinetic study of the 1-mo depot formulations of each peptide after s.c. administration to rabbits.

Electrophoresis published new progress about Blood analysis. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ganapathy, Birintha published the artcileBioremediation of palm oil mill effluent (POME) using indigenous Meyerozyma guilliermondii, Application In Synthesis of 584-02-1, the main research area is palm oil mill effluent bioremediation Meyerozyma wastewater treatment; Aerobic treatment; Bioremediation; Chemical oxygen demand; Indigenous; Lipase; Oil and grease; Palm oil mill effluent.

Despite being a key Malaysian economic contributor, the oil palm industry generates a large quantity of environmental pollutant known as palm oil mill effluent (POME). Therefore, the need to remediate POME has drawn a mounting interest among environmental scientists. This study has pioneered the application of Meyerozyma guilliermondii with accession number (MH 374161) that was isolated indigenously in accessing its potential to degrade POME. This strain was able to treat POME in shake flask experiments under aerobic condition by utilizing POME as a sole source of carbon. However, it has also been shown that the addition of suitable carbon and nitrogen sources has significantly improved the degradation potential of M. guilliermondii. The remediation of POME using this strain resulted in a substantial reduction of COD (COD) of 72%, total nitrogen of 49.2% removal, ammonical nitrogen of 45.1% removal, total organic carbon of 46.6% removal, phosphate of 60.6% removal, and 92.4% removal of oil and grease after 7 days of treatment period. The strain also exhibited an extracellular lipase activity which promotes better wastewater treatment. Addnl., Fourier transform IR spectroscopy (FTIR) and gas chromatog.-mass spectrometry (GC-MS) analyses have specifically shown that M. guilliermondii strain can degrade hydrocarbons, fatty acids, and phenolic compounds present in the POME. Ultimately, this study has demonstrated that M. guilliermondii which was isolated indigenously exhibits an excellent degrading ability. Therefore, this strain is suitable to be employed in the remediation of POME, contributing to a safe discharge of the effluent into the environment.

Environmental Science and Pollution Research published new progress about Bioremediation. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Application In Synthesis of 584-02-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Hao published the artcileThe enhanced mechanisms of Hansschlegelia zhihuaiae S113 degrading bensulfuron-methyl in maize rhizosphere by three organic acids in root exudates, Name: (S)-2-hydroxysuccinic acid, the main research area is bensulfuronmethyl degradation organic acid root exudate maize rhizosphere Hansschlegelia; Bensulfuron-methyl; Chemotactic response; Hansschlegelia zhihuaiae S113; Maize rhizosphere; Organic acids.

The residues of bensulfuron-Me (BSM), a sulfonylurea herbicide, in soil have caused serious damage to the rotation of susceptible crops. Many studies have reported that the removal of BSM in soil was achieved by adding degrading bacteria. However, the mechanisms used by bacteria to degrade BSM in the crop rhizosphere remain unclear. In this study, a BSM-degrading bacterium, Hansschlegelia zhihuaiae S113, was applied to investigate the enhancement of effects mediated by organic acids during the bioremediation of BSM-contaminated maize rhizosphere soil. Organic acids, such as -malic acid, tartaric acid, and fumaric acid, identified in maize root exudates, significantly stimulated the expression of cheA, which encoded the histidine kinase in strain S113 and contributed to the chemotactic response. This process accelerated the accumulation of strain S113 around the maize roots and promoted the colonization process on maize roots. The growth of strain S113 was significantly increased by -malic acid but not tartaric acid or fumaric acid. After the S113 suspension was root-irrigated to BSM-contaminated soil, the d. of strain S113 colonizing root surfaces and in rhizosphere soil reached 1.1 x 104 cells/g for roots and 4.9 x 104 cells/g in dry soil at 15 d, leading to 80.9% BSM degradation efficiency. The treatment with the addition of a mixture of S113 and -malic acid completely degraded BSM in rhizosphere soil due to the strong attraction and growth promotion of strain S113 by -malic acid, with a higher efficiency than that with the extra addition of fumaric acid (89.7%) or tartaric acid (87.0%). This paper revealed the enhancement effects of organic acids identified in root exudates for the in situ bioremediation of BSM-contaminated rhizosphere soil.

Ecotoxicology and Environmental Safety published new progress about Bioremediation. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Name: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Jia-Jia published the artcileGC-MS profile of Hua-Feng-Dan and RNA-Seq analysis of induced adaptive responses in the liver, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Hua Feng Dan RNA sequence liver bioinformatic signaling GCMS; GC-MS; GEO database; Hua-Feng-Dan; RNA-seq; adaptation; bioinformatics.

Hua-Feng-Dan is a patent Chinese medicine for stroke recovery and various diseases. This study used GC-MS to profile its ingredients and RNA-Seq to analyze the induced adaptive response in the liver. Hua-Feng-Dan was subjected to steam distillation and solvent extraction, followed by GC-MS anal. Mice were orally administered Hua-Feng-Dan and its “”Guide drug”” Yaomu for 7 days. Liver pathol. was examined, and total RNA isolated for RNASeq, followed by bioinformatic anal. and quant. real-time PCR (qPCR). Forty-four volatile and fifty liposol. components in Hua-Feng-Dan were profiled and analyzed by the NIST library and their concentrations quantified. The major components (>1%) in volatile (5) and liposol. (10) were highlighted. HuaFeng-Dan and Yaomu at hepatoprotective doses did not produce liver toxicity as evidenced by histopathol. and serum enzyme activities. GO Enrichment revealed that Hua-Feng-Dan affected lipid homeostasis, protein folding, and cell adhesion. KEGG showed activated cholesterol metabolism, bile secretion, and PPAR signaling pathways. Differentially expressed genes (DEGs) were identified by DESeq2 with p < 0.05 compared to controls. Hua-Feng-Dan produced more DEGs than Yaomu. qPCR on selected genes largely verified RNA-Seq results. Ingenuity Pathways Anal. of the upstream regulator revealed activation of MAPK and adaptive responses by Hua-FengDan, and Yaomu was less effective. Hua-Feng-Dan-induced DEGs were highly correlated with the Gene Expression Omnibus database of chem.-induced adaptive transcriptome changes in the liver. GC-MS primarily profiled volatile and liposol. components in Hua-FengDan. Hua-Feng-Dan at the hepatoprotective dose did not produce liver pathol. changes but induced metabolic and signaling pathway activations. The effects of Hua Feng-Dan on liver transcriptome changes point toward induced adaptive responses to program the liver to produce hepatoprotective effects. Frontiers in Pharmacology published new progress about Bioinformatics. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

El-Seesy, Ahmed I. published the artcileImpacts of octanol and decanol addition on the solubility of methanol/hydrous methanol/diesel/biodiesel/Jet A-1 fuel ternary mixtures, COA of Formula: C8H18O, the main research area is octanol decanol hydrous methanol diesel biodiesel jetA1 fuel solubility.

This study attempts to enhance the mixture instability of methanol/hydrous methanol mixed with diesel fuel, waste cooking oil (WCO) biodiesel, and Jet A-1 fuel using n-octanol and n-decanol as cosolvent at numerous temperatures of 10°C, 20°C, and 30°C. The experiment is divided into two stages: first, blending pure methanol with diesel oil, Jet A-1, and WCO biodiesel individually utilizing n-octanol and n-decanol as cosolvent at various temperatures Second, combining hydrous methanol (90% methanol + 10 wt% water) with diesel oil, Jet A-1, and WCO biodiesel independently and applying n-octanol and n-decanol as cosolvent at different temperatures Pure methanol or hydrous methanol is mixed with the base fuels at different mixing proportions varying from 0 to 100 vol% with 10 vol% increments. The co-solvent, mainly n-octanol and n-decanol (titrant), is progressively and sep. inserted into the tube with continuous shaking by utilizing a high-precision pipet until the ternary mixtures’ phase borders seem. The findings demonstrate phase separation in pure methanol-diesel and pure methanol-Jet A-1 combinations even when the blend temperature increased to 60°C. The pure methanol/biodiesel combination proves complete solubility without adding an external agent. The results also illustrate that the ambient temperature considerably affects the stability of mixture and amount of cosolvent in the blend. n-Octanol and n-decanol showed promising performance in enhancing the phase stability issue of methanol and hydrous methanol with the base fuels. It can be deduced that the min. amount of cosolvent is recorded for biodiesel-hydrous methanol, Jet A-1-hydrous methanol, and diesel-hydrous methanol, resp.

RSC Advances published new progress about Biodiesel fuel. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, COA of Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sidharth published the artcileComparison of properties of ternary fuel blends of diesel-octanol with biodiesel, COA of Formula: C8H18O, the main research area is biodiesel octanol nitrogen oxide transesterification petroleum diesel.

Biodiesel is adopted by many countries as a substitute to diesel and is used in blended form in a diesel engine. It has very similar properties to diesel. However, owing to slightly higher viscosity, d. and nitrogen oxide (NOX) emissions on burning, it still is not the best choice. Octanol, have similar properties to diesel. Octanol has added oxygen and also reduces the NOX emissions due to the quenching effect in the cylinder. However, its lower calorific value shall reduce engine performance. In the current study, waste cooking oil biodiesel is produced by a single step transesterification process and several blends of diesel, biodiesel and octanol were prepared Fourier-transform IR spectroscopy (FTIR) and oxidation stability tests of the produced biodiesel were performed. FTIR test confirmed the presence of biodiesel. Oxidation stability test of biodiesel was also passed as the induction time in over 6 h. Blends of diesel and octanol were prepared in proportion of diesel (95%, 90%, 85% and 80%) and octanol (5%, 10%, 15% and 20%). These blends were added to 3%, 5% and 10% biodiesel. Several physico-chem. properties namely d., viscosity, calorific value, flash point and cold filter plugging point (CFPP) were determined as per ASTM standards It is concluded that the 10% octanol, 90% diesel when mixed with 10% biodiesel showed very similar properties to diesel and shall be a viable alternative to petroleum diesel.

IOP Conference Series: Materials Science and Engineering published new progress about Biodiesel fuel. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, COA of Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xuan, Tiemin published the artcileAn optical study on spray and combustion characteristics of ternary hydrogenated catalytic biodiesel/methanol/n-octanol blends; part I: Spray morphology, ignition delay, and flame lift-off length, Category: alcohols-buliding-blocks, the main research area is biodiesel methanol octanol blend spray morphol optical combustion.

A fundamental study on spray morphol., ignition delay, and flame lift-off length of two ternary hydrogenated catalytic biodiesel (HCB)/methanol/n-octanol blends were carried out by performing visualization tests through high-speed Schlieren and OH* chemiluminescence simultaneously within a quiescent combustion chamber. The two ternary mixtures are 68% by volume HCB, 17% octanol, and 15% methanol, as well as 58% HCB, 17% octanol, and 25% methanol, which are denoted as M15 and M25 resp. It was found that the mixture stability of HCB/methanol is significantly enhanced using n-octanol as the co-solvent. The pure HCB (M0) was also tested under the same operating conditions as references All the sprays were injected into the chamber through an injector equipped with a single-hole nozzle. Exptl. results show that spray of M0 presents a faster penetration, following by M15 and M25, which is mainly caused by the shorter ignition delay of M0; With the increase of methanol percentage in the blends, the stoichiometric fuel mass fraction increases because of the high oxygen content of methanol, which contributes to a longer ignition delay; There are two factors of the blended fuel properties affecting flame lift-off length, namely stoichiometric fuel mass fraction and cetane number It was found the cetane number plays a much more important role than that of stoichiometric fuel mass fraction on lift-off length.

Fuel published new progress about Biodiesel fuel. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Khajone, Vijay B. published the artcileBronsted acid functionalized phthalocyanine on perylene diimide framework knotted with ionic liquid: An efficient photo-catalyst for production of biofuel component octyl levulinate at ambient conditions under visible light irradiation, Application of n-Octanol, the main research area is Bronsted acid functionalized phthalocyanine perylene diimide framework esterification; biofuel octyl levulinate visible light irradiation ionic liquid photocatalyst.

Novel Broensted acid functionalized phthalocyanine on perylene diimide framework knotted with ionic liquid (BAFPcPDIL) was synthesized and confirmed by instrumentation techniques. DRS-spectrum and Hammett value has been determined to confirm band-gap and proton levels of photo-catalyst, resp. The photo-catalytic performance was evaluated by production of octyl levulinate (OL) using levulinic acid (LA) with n-octyl alc. (OA) under visible light irradiations. Response surface methodol. (RSM) with Box-Behnken design (BBD) with 29 experiments was applied to explore consequences of 4 crucial process variables: catalyst loading (A), molar ratio of reactants (B) and power of visible light (C), duration in hour (D) on OL yield. From the model, the optimum conditions for the utmost conversion were found as: 10 mg catalyst with (1:1) alc. to LA molar ratio under 12 W lamp, in 12 h for completing esterification reaction with 95.58% yield of OL. With optimum conditions, various alkyl esters such as Me levulinate 92.14%, Et levulinate 93.12%, Pr levulinate 91.45%, isoPr levulinate 92.38%, Bu levulinate 85.13%, n-pentyl levulinate 86.35%, n-hexyl levulinate 89.57%, CMe3 levulinate 91.58%, were successfully synthesized with excellent yields. The plausible photocatalytic mechanism of the esterification reaction was also described. The study was extended on blending of OL with diesel sample in 10-30%, found comparable result of d., kinematic viscosity, calorific values, cetane number, flash, fire and pour point of the blended samples with blank diesel sample and appreciable changes in exhaust gases of 25% blended diesel sample. Addnl., BAFPcPDIL displayed good recyclability without loss of photo reactivity after 4 runs.

Fuel published new progress about Biodiesel fuel. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lapsiri, Wanticha published the artcileViability of Lactobacillus plantarum TISTR 2075 in Different Protectants during Spray Drying and Storage, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is Lactobacillus probiotic viability protectant spray drying storage.

Spray drying was applied for the production of Lactobacillus plantarum TISTR 2075 powder using maltodextrin as the carrier. A survival rate of 0.85% was achieved for this probiotic bacteria after spray drying. To improve the survival of this strain during the spray-drying process and storage, various protectants were added before drying. These included protein, trehalose, fibersol, ascorbic acid, isomalt, palatinose, and gum acacia. The results indicated that trehalose and protein (a combination of soy protein isolate and milk protein concentrate) significantly (P < 0.05) enhanced the viability during spray drying, with survival rates of 57.70 and 25.31%, resp. Survival of the dried strain was also monitored over a period of 12 mo' storage at 4 and 25°C. Higher temperature induced lower viability of the strain in all protectants during this long-term storage. Accelerated storage tests using temperatures of 37, 45, 60, and 80°C were also applied to the spray-dried powders. A temperature-dependent prediction model was developed to determine the viability of the spray-dried L. plantarum TISTR 2075 in different protectants for long-term storage. Drying Technology published new progress about Biodegradation. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yu, Chao published the artcileA “”graphdiyne-like”” anti-fouling TBBPA molecularly imprinted membrane synthesized based on the delayed phase inversion method: A concomitant permeability and selectivity, HPLC of Formula: 7575-23-7, the main research area is antifouling molecularly imprinted membrane delayed phase inversion nanomaterial.

Integration of membrane and nanomaterial is a forward-looking research orientation, which can effectively overcome the permeability-selectivity trade-off relationship and improve anti-fouling performance. However, the current combination methods usually suffer from defects due to the aggregation and embedding of nanomaterials, resulting in serious performance deterioration of membrane during continuous operation process. Herein, “”graphdiyne-like”” Tetrabromobisphenol A molecularly imprinted membranes with uniform and dense SiO2 layer, namely TB-MIMs, are successfully prepared by delayed phase inversion method (DPIM). We found that the membrane prepared by DPIM exhibits both promoted pure water flux (405 L m-2 h-1) and enhanced adsorption capacity (83.476 mg g-1) by comparing with the membranes prepared by blending and grafting methods. The role of molecularly imprinting technique contributes to improving the selectivity of TB-MIMs toward TBBPA, leading to a high selectivity factor of 3.39, 3.27 and 3.05 for bisphenol A, p-tert-Bu phenol and 4, 4′-dihydroxybiphenyl, resp. Moreover, the flux of TB-MIMs is nearly recovered to an original level after washing the bovine serum albumin fouled membrane surface with deionized water. Notably, the TB-MIMs presents a high rejection rate for bovine serum albumin (94%), humic acid (92%) and alginic acid (91%) in natural water, indicating its bright actual application value. These superior performances highlight the advantage of DPIM strategy over traditional methods in terms of combination between membrane and nanomaterials.

Journal of Membrane Science published new progress about Binding energy. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, HPLC of Formula: 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts