Author: tianli

Nebesny, Ewa published the artcileProperties of sucrose-free chocolates enriched with viable lactic acid bacteria, Quality Control of 64519-82-0, the main research area is chocolate viscosity isomalt yogurt lactic acid bacteria.

Chocolate formulated with isomalt and enriched with lactic acid bacteria Streptococcus thermophilus MK-10 and Lactobacillus delbrueckii subsp. bulgaricus 151, added in the form of powd. yogurt, prepared by spray-drying is a sucrose-free, low-calorie product with functional properties. The technique of the production of chocolate sweetened with isomalt and containing live cells of the aforementioned bacterial strains was established. Physicochem. and sensory properties of this product as well as survival of cells during 6-mo storage at 4 and 18 °C were determined The isomalt-containing yogurt chocolates displayed satisfactory sensory attributes. Their calorific value and consistency (hardness) were similar to those of control sucrose-free chocolates. The total acidity of yogurt and standard milk chocolates was also similar, whereas yogurt-containing dark chocolates displayed higher acidity. The characteristics of yogurt-containing chocolates were a relatively low solid substance content (96.82-96.91% weight/weight), low Casson viscosity and yield value for milk chocolate masses, and enhanced rheol. parameters for dark chocolate masses compared with control sucrose-free chocolates. Because the total number of lactic acid bacteria after 6-mo storage at 4 and 18 °C was high (approx. 107 cfu/g), the sucrose-free yogurt-containing chocolates can be regarded as functional foods.

European Food Research and Technology published new progress about Dark chocolate. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Quality Control of 64519-82-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nebesny, Ewa published the artcileDark chocolates supplemented with Lactobacillus strains, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is Lactobacillus dark chocolate sucrose aspartama isomalt.

Dark chocolate masses and chocolates were supplemented with viable cells of 2 bacterial strains Lactobacillus caseii and Lactobacillus paracasei with potential probiotic properties, which were lyophilized in milk. Total number of live bacteria in the lyophilizate was 7.9 × 109 cfu/g. Sucrose or isomalt and aspartame were used as bulking substances and sweeteners. Sensory attributes of these chocolates were not different from that of traditional chocolates. Calorie value of sucrose-free chocolate was lower by approx. 11.1-14.6% (dependent on their formulation) relative to chocolate sweetened with sucrose. Chocolate, which contains isomalt and aspartame can be consumed by diabetics. Numbers of live L. casei and L. paracasei cells in the examined batches of chocolate were very high and approached 106-107 cfu/g after 12 mo of keeping at 4 and 18 °C. Neither the texture nor the total and volatile acidity of chocolate masses were changed by addition of the lyophilized preparation of Lactobacillus cells. Casson yield values of dark sucrose-free chocolate masses supplemented with this lyophilizate were decreased by approx. 3-55% (dependently on fat contents in these masses) as compared to that of analogous chocolate masses sweetened with sucrose.

European Food Research and Technology published new progress about Dark chocolate. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Kun published the artcileSynthesis, structure, and the second-order nonlinear optical properties of a borate-carboxylic acid compound: KB(L-(-)-C4H4O5]2m·H2O, Application of (S)-2-hydroxysuccinic acid, the main research area is potassium bismalic acid borate second order nonlinear optical property.

A new organic-inorganic hybrid noncentrosym. potassium bis(malic acid)-borates KB(L-(-)-C4H4O5)2·H2O was synthesized by solution method. It was characterized by elemental anal., FT-IR, TGA and single-crystal X-ray crystallog. It crystallizes in the monoclinic space group P21/c with a = 5.546(6), b = 11.985(13), c = 9.952(11) β, β = 97.522(17)°, V = 655.8(13) Δ3, Z = 2, Dc = 1.682 g/cm3, μ(MoKa) = 0.46 mm-1 and F(000) = 340. 5009 reflections were measured and 2893 independent reflections(Rint = 0.051) were used for further refinement. Single-crystal X-ray diffraction reveals that the complex exhibits a threedimensional pseudo tunnel structure consisting of fundamental building block [B(L-(-)-C4H4O5)2]- anions. The small cavities are occupied by the H2O mols., which stabilize the whole structure by O-H···×O hydrogen bonds. The complex exhibits nonlinear optical effect as high as 1.5 times that of KDP standard

Chinese Journal of Structural Chemistry published new progress about Crystal growth. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Application of (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ahn, Jinhyeok published the artcileThiol-ene UV-curable sponge electrolyte for low-voltage color changing wearable tactile device, Category: alcohols-buliding-blocks, the main research area is sponge electrolyte low voltage color changing wearable tactile device.

Interest in developing advanced flexible materials that are stable, mech. deformable, lightweight, cost-effective, and eco-friendly is ever-growing to support high-performance state-of-the-art wearable electronic devices. Another critical requirement of wearable devices is low energy consumption during operation for prolonged use. Herein, we demonstrate a compressible electrochromic device (ECD) using the three-dimensional (3D) compressible sponge electrolyte layer. A 3D porous sponge was fabricated using a facile and eco-friendly method of leaching sugar, a pore-creating agent, from an UV-cured skeletal structure. The simple structure of a compressible ECD is advantageous for its applicability as an optical tactile sensor device. A low-voltage operation, as evidenced by optical measurements, can ensure the long-term performance of the sensor. Furthermore, the color change in the ECD that occurs with the applied pressure acts as an effective pressure-sensing mechanism for the system involved. Thus, compressible sponge electrolytes layers are promising for various wearable tactile device applications.

Polymer published new progress about Color (change). 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

De Flaviis, Riccardo published the artcileWheat classification according to its origin by an implemented volatile organic compounds analysis, Name: n-Octanol, the main research area is ethanol hexanal acetic acid classification wheat quality; GC–MS; Pedoclimatic conditions; SPME; Volatile organic compounds; Wheat species.

Food volatile organic compounds (VOCs) anal. is a useful tool in authentication and classification processes, but, to date, the anal. of wheat VOCs is still little explored. In this study a method of anal. based on solid phase microextraction coupled with gas chromatog.-mass spectrometry was optimized by testing different types of fibers, sample preparation methods and amounts, extraction temperatures and times, desorption times and oven programs. The anal. was applied to six wheat cultivars harvested in different areas, and permitted to identify 158 VOCs, of which 98 never found before. A principal component anal. performed on the dataset showed that the area of cultivation accounted for the highest source of variability. Partial least squares anal. permitted to correctly classify wheats based on their cultivation area and species, and to identify the most discriminant VOCs. These results are promising for the study of the influence of geog. origin on wheat quality.

Food Chemistry published new progress about Classification. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Name: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pinheiro, Fernanda C. published the artcileDispersive liquid-liquid microextraction of Cd, Hg and Pb from medicines prior to ICP OES determination according to the United States Pharmacopeia, Application In Synthesis of 111-87-5, the main research area is cadmium mercury lead tablet dispersive liquid microextraction ICPOES.

A simple, sensitive and matrix-effect free anal. method for simultaneous determination of Cd, Hg and Pb in drug samples (i.e., com. dosage tablets) by inductively coupled plasma optical emission spectrometry (ICP OES) has been developed. According to the USP (USP) Chapter 232, those metals are considered elemental impurities from class 1 and they must be assessed in pharmaceutical production as well as in quality control evaluation. In order to increase the sensitivity of the anal., dispersive liquid-liquid microextraction (DLLME) was performed and seven factors affecting analyte extraction were optimized by multivariate anal. A microvolume of analyte enriched phase was directly introduced into the plasma using a multi-nebulizer, providing a high enrichment factor. When compared to conventional ICP OES anal., DLLME improves the limit of quantitation (LOQ) values on average 40-fold for all analytes. Consequently, LOQ values were significantly lower than their permissible daily exposure limits for oral drugs. Accuracy was evaluated by addition and recovery experiments following USP recommendations in eight com. drug samples. Recovery and RSD values were within the range of 90-108% and 1-9%, resp.

Analytical Methods published new progress about Centrifugation. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Kai published the artcileFruity aroma modifications in Merlot wines during simultaneous alcoholic and malolactic fermentations through mixed culture of S. cerevisiae, P. fermentans, and L. brevis, Safety of 3-(Methylthio)propan-1-ol, the main research area is alc malolactic fermentation Lactobacillus brevis Saccharomyces cerevisiae Pichia fermentans.

As a group of wine lactic acid bacteria, Lactobacillus has gained growing interest in malolactic fermentation due to possessing diverse aroma-related enzymes. In this study, a Lactobacillus brevis 26 with high β-glucosidase activity was isolated, and co-inoculated with yeasts (Saccharomyces cerevisiae and Pichia fermentans) to characterize fruity aroma modifications in Merlot wine. Compared with the traditional inoculation (sequential inoculation of L. brevis 26 after alc. fermentation by yeasts), co-inoculation of the three species induced simultaneous alc. and malolactic fermentations, leading to a pronounced reduction in total fermentation duration. P. fermentans increased L. brevis 26 cell viability when co-fermented with the predominant species S. cerevisiae. Meanwhile, the β-glucosidase activity of L. brevis 26 elevated terpene contents, and P. fermentans induced the production of higher alc. acetates and fatty acid Et esters. Sensory anal. showed that co-inoculation-based wines had enhanced complexity of fruity aroma profiles associated with jammy and temperate fruity notes.

LWT–Food Science and Technology published new progress about Cell viability. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Safety of 3-(Methylthio)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Prestes, Alessandro de Souza published the artcileMethylglyoxal disrupts the functionality of rat liver mitochondria, SDS of cas: 97-67-6, the main research area is liver mitochondria superoxide phosphorylation bioenergetics methylglyoxal; High-resolution respirometry; Methylglyoxal; Mitochondria; Oxidative stress.

Methylglyoxal (MG) is a reactive metabolite derived from different physiol. pathways. Its production can be harmful to cells via glycation reactions of lipids, DNA, and proteins. But, the effects of MG on mitochondrial functioning and bioenergetic responses are still elusive. Then, the effects of MG on key parameters of mitochondrial functionality were examined here. Isolated rat liver mitochondria were exposed to 0.1-10 mM of MG to determine its toxicity in the mitochondrial viability, membrane potential (Δψm), swelling and the superoxide (O·-2) production Besides, mitochondrial oxidative phosphorylation parameters were analyzed by high-resolution respiratory (HRR) assay. In this set of experiments, routine state, PM state (pyruvate/malate), oxidative phosphorylation (OXPHOS), LEAK respiration, electron transport system (ETS) and oxygen residual (ROX) states were evaluated. HRR showed that PM state, OXPHOS CI-Linked, LEAK respiration, ETS CI/CII-Linked and ETS CII-Linked/ROX were significantly inhibited by MG exposure. MG also inhibited the complex II activity, and decreased Δψm and the viability of mitochondria. Taken together, our data indicates that MG is an inductor of mitochondrial dysfunctions and impairs important steps of respiratory chain, effects that can alter bioenergetics responses.

Chemico-Biological Interactions published new progress about Cell viability. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, SDS of cas: 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Veeraperumal, Suresh published the artcilePolysaccharides from Gracilaria lemaneiformis promote the HaCaT keratinocytes wound healing by polarised and directional cell migration, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is polysaccharide Gracilaria lemaneiformis wound healing promoter cell proliferation; Cell migration; Cell polarisation; Gracilaria lemaneiformis; Human keratinocyte; Wound healing.

In this study, we evaluated the wound healing activity of polysaccharides fractions from Gracilaria lemaneiformis. Three purified fractions, namely, GLP-1, GLP-2 and GLP-3 were obtained from anion-exchange chromatog. and were evaluated for their cell proliferation activity. Among the three fractions, the fraction GLP-2 promoted cell proliferation at a concentration of 100μg/mL. Further, chem. and structural anal. of GLP-2 revealed it to be a homogenous and repeating structure of alternating 4-linked 3,6-anhydro-α-L-galactopyranosyl and 3-linked β-D-galactopyranosyl units with sulfate residues. Further, we analyzed the wound healing activities of the fraction GLP-2 and its underlying mechanisms. The results showed that GLP-2 promotes cell proliferation and migration through activation of PI3 K/aPKC signaling during human keratinocytes wound healing. Based on the findings in this study, we concluded that the wound healing activities of the GLP-2 fraction can provide the scientific basis for the development of G. lemaneiformis polysaccharides based product for wound management.

Carbohydrate Polymers published new progress about Cell migration. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Altassan, Ruqaiah published the artcileInternational consensus guidelines for phosphoglucomutase 1 deficiency (PGM1-CDG): Diagnosis, follow-up, and management, COA of Formula: C6H12O6, the main research area is review phosphoglucomutase diagnosis protein glycosylation; d-galactose; PGM1-CDG; congenital disorder of glycosylation; management guidelines; phosphoglucomutase 1 deficiency.

Phosphoglucomutase 1 deficiency is a rare genetic disorder that affects glycogen metabolism, glycolysis, and protein glycosylation. Previously known as GSD XIV, it was recently reclassified as a congenital disorder of glycosylation, PGM1-CDG. PGM1-CDG usually manifests as a multisystem disease. Most patients present as infants with cleft palate, liver function abnormalities and hypoglycemia, but some patients present in adulthood with isolated muscle involvement. Some patients develop life-threatening cardiomyopathy. Unlike most other CDG, PGM1-CDG has an effective treatment option, -galactose, which has been shown to improve many of the patients’ symptoms. Therefore, early diagnosis and initiation of treatment for PGM1-CDG patients are crucial decisions. In this article, our group of international experts suggests diagnostic, follow-up, and management guidelines for PGM1-CDG. These guidelines are based on the best available evidence-based data and experts’ opinions aiming to provide a practical resource for health care providers to facilitate successful diagnosis and optimal management of PGM1-CDG patients.

Journal of Inherited Metabolic Disease published new progress about Cardiomyopathy. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, COA of Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts