Author: tianli

Horne, Gregory P. published the artcileDoes addition of 1-octanol as a phase modifier provide radical scavenging radioprotection for N,N,N’,N’-tetraoctyldiglycolamide (TODGA)?, Application of n-Octanol, the main research area is octanol phase modifier radical scavenging radioprotection TODGA fuel reprocessing.

To mitigate third phase formation in next generation used nuclear fuel reprocessing technologies, the addition of 1-octanol has been trialed. However, contradictory reports on the radiolytic effect of 1-octanol incorporation on separation ligand degradation need to be resolved. Here, 50 mM N,N,N’,N’-tetraoctyldiglycolamide (TODGA) dissolved in n-dodecane was gamma irradiated in the presence and absence of 1-octanol (2.5-10 vol%) and a 3.0 M HNO3 aqueous phase. Radiation-induced TODGA degradation exhibited pseudo-first-order decay kinetics as a function of absorbed gamma dose for all investigated solution and solvent system formulations. The addition of 1-octanol afforded diametrically different effects on the rate of TODGA degradation depending on solvent system formulation. For organic-only irradiations, 1-octanol promoted TODGA degradation (d = 0.0057 kGy-1 for zero 1-octanol present vs. ∼0.0073 kGy-1 for 7.5-10 vol%) attributed to a favorable hydrogen atom abstraction reaction free energy (-0.31 eV) and the ability of 1-octanol to access a higher yield of n-dodecane radical cation (RH+̇) at sub-nanosecond timescales. This was rationalized by determination of the rate coefficient (k) for the reaction of 1-octanol with RH+̇, k = (1.23 ± 0.07) x 1010 M-1 s-1. In contrast, irradiation in the presence of 1-octanol and a 3.0 M HNO3 aqueous phase afforded significant radioprotection (d = 0.0054 kGy-1 for zero 1-octanol present vs. ≤ 0.0044 kGy-1 for >2.5 vol%) that increases with 1-octanol concentration, relative to the single phase, organic-only solutions This effect was attributed to the extraction of sufficiently high concentrations of HNO3 and H2O into the organic phase by TODGA and 1-octanol as adducts which interfere with the hydrogen atom abstraction process between the 1-octanol radical and TODGA. The findings suggest that the addition of 1-octanol as a phase modifier will enhance the radiation robustness of TODGA-based separation technologies under envisioned solvent system conditions in the presence of aqueous HNO3.

Physical Chemistry Chemical Physics published new progress about Electron beams. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shen, Wenbo published the artcileElectrically switchable light transmittance of epoxy-mercaptan polymer/nematic liquid crystal composites with controllable microstructures, Product Details of C17H28O8S4, the main research area is epoxy resin mercaptan nematic liquid crystal composite light transmittance; electrooptical property.

In this paper, we report the design, preparation and properties of epoxy-mercaptan polymer/nematic liquid crystal (LC) composites with elec. switchable optical transmittance. It is found that the polymer microstructure can be regulated from porous structure to microspheres or beads by appropriately modulating the curing temperature, the mol. structure of mercaptan, as well as the compositions of epoxy, mercaptan and nematic LC host. Under an external elec. field, the thin films based on such composites can switch from opaque to transparent. The electro-optical performance is found to be highly dependent on the polymer microstructures and the optimum characteristics can be achieved in the composite with a microstructure of smaller microspheres. The possible mechanism for the formation of polymer microspheres and the effects of the microstructures on the electro-optical characteristics of the composites are also discussed. This work is expected to provide an efficient way to control the microstructure of epoxy/mercaptan polymer and develop the composites with switchable optical transmittances for both civil and military applications.

Polymer published new progress about Electric field. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Product Details of C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dani, Vivek D. published the artcileComparison of metabolomic responses of earthworms to sub-lethal imidacloprid exposure in contact and soil tests, SDS of cas: 97-67-6, the main research area is Eisenia metabolomic response imidacloprid contact soil test; Contact exposure; Eisenia fetida; Energy disruption; Gluconeogenesis; Neonicotinoids; Soil exposure.

Eisenia fetida earthworms were exposed to sub-lethal levels of imidacloprid for 48 h via contact filter paper tests and soil tests. After the exposure, 1H NMR (NMR) metabolomics was used to measure earthworm sub-lethal responses by analyzing the changes in the polar metabolite profile. Maltose, glucose, malate, lactate/threonine, myo-inositol, glutamate, arginine, lysine, tyrosine, leucine, and phenylalanine relative concentrations were altered with imidacloprid exposure in soil. In addition to these metabolites (excluding leucine and phenylalanine), fumarate, ATP, inosine, betaine, scyllo-inositol, glutamine, valine, tryptophan, alanine, tyrosine, and isoleucine relative concentrations shifted with imidacloprid exposure during contact tests. Overall, imidacloprid exposure in soil induces a less pronounced response in metabolites glucose, maltose, fumarate, adenosine-5′-triphosphate (ATP), inosine, scyllo-inositol, lactate/threonine, and tyrosine in comparison to the response observed via contact tests. Thus, our study highlights that tests in soil can result in a different metabolic response in E. fetida and demonstrates the importance of different modes of exposure and the extent of metabolic perturbation in earthworms. Our study also emphasizes the underlying metabolic disruption of earthworms after acute sub-lethal exposure to imidacloprid.

Environmental Science and Pollution Research published new progress about Eisenia fetida. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, SDS of cas: 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Can Karaca, Asli published the artcileEffects of polyols on gelation kinetics, gel hardness, and drying properties of alginates subjected to internal gelation, Application of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is polyol alginate gelation gel hardness drying viscosity.

This study investigates the influence of polyols (glycerol, sorbitol, mannitol and isomalt) on thickening of sodium alginate solutions, hardness and drying kinetics of calcium alginate gels and their glass transition temperature (Tg) after drying. Two alginate samples with 30% and 63% guluronate were used to prepare gels by internal gelation based on release of calcium ions from CaCO3 by hydrolysis of glucono-delta-lactone. The lag period, determined from viscosity-time plots, for the low-G alginate was about 13 min less than that for the high-G alginate. Presence of polyols did not influence the lag period values. The hardness value for high-G gels was about 100 g greater than that of low-G gels. Addition of isomalt resulted in gels with higher hardness values compared to other polyols. Presence of polyols had a significant effect on residual moisture and Tg of alginate films. Initial drying rates were the same for all samples but gels containing glycerol had high residual moisture (∼3.5 g/100 g) and produced very flexible films, whereas mannitol containing samples had low moisture (∼0.2 g/100 g) and produced brittle films. Tg of the films varied from -88°C to 35°C and decreased upon polyol addition

LWT–Food Science and Technology published new progress about Drying process. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Application of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lyu, Jian published the artcileCharacterization of water status and water soluble pectin from peaches under the combined drying processing, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is water soluble pectin peach drying processing; Average molar mass; Degradation; Degree of esterification; Osmotic dehydration; Pectin.

Characterization of water status and water soluble pectin (WSP) from peach were evaluated after different stage of combined drying in which osmotic dehydration (OD) was considered as the pre-treatment prior to instant controlled pressure drop (DIC) – assisted IR radiation drying (IRD) (IR-DIC). Results showed that the contents of free water and immobilized water decreased to 0 g after the combined drying. The content of bound water increased after IRD treatment. The residual PME activity in peach slices was 153.3-179.6% after OD treatment, while, the PG were totally inactivated after IRD. The degree of esterification (DE), WSP content and average molar mass (Mw) decreased significantly (from 75.00 to 43.74, from 156.00 to 74.91 mg/g AIR and from 2.28 to 0.49 × 105 Da, resp.) after the combined drying. The neutral sugar of WSP was mainly composed by galactose, arabinose and rhamnose, whose contents decreased after the combined drying. However, OD treatment would slow down the degradation There was a low peak at 1740 cm-1 in FT-IR spectrum observed for WSP after IRD and DIC treatment, which might illustrate the degradation of WSP during the combined drying.

International Journal of Biological Macromolecules published new progress about Drying process. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Caputo, Lucia published the artcileImpact of drying methods on the yield and chemistry of Origanum vulgare L. essential oil, Related Products of alcohols-buliding-blocks, the main research area is Origanum essential oil carvacrol drying thermal stress.

Oregano (Origanum vulgare L.) is mainly cultivated, both as fresh and dried herb, for several purposes, such as ailments, drugs, and spices. To evaluate the influence of some drying methods on the chem. composition of the essential oil of oregano, its aerial parts were dehydrated by convective drying techniques (shade, static oven), microwave-assisted heating (three different treatments) and osmotic treatment. The oils were analyzed by GC-FID and GC-MS. The highest essential oil yield was achieved from microwave and shade drying methods. In total, 39 components were found, with carvacrol (ranging from 56.2 to 81.4%) being the main constituent; other compounds present in lower amounts were p-cymene (1.6-17.7%), γ-terpinene (0.8-14.2%), α-pinene (0.1-2.1%), thymol Me ether (0.4-1.8%) and thimoquinone (0.5-3.5%). The essential oil yields varied among the different treatments as well as the relative compositions The percentages of p-cymene, γ-terpinene and α-pinene decreased significantly in the dried sample compared with the fresh sample; on the other hand, carvacrol, isoborneol and linalool increased significantly in the dried materials. The choice of the drying method for obtaining the essential oil therefore appears crucial not only in relation to the higher yield but also and above all in reference to the percentage presence of components that can direct the essential oil toward an appropriate use.

Scientific Reports published new progress about Drying process. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lim, Juhyeon published the artcilePhosphoenolpyruvate depletion mediates both growth arrest and drug tolerance of Mycobacterium tuberculosis in hypoxia, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is Mycobacterium hypoxia phosphoenolpyruvate growth inhibition drug tolerance; drug tolerance; metabolic remodeling; phosphoenolpyruvate; synthetic lethality; tuberculosis.

Mycobacterium tuberculosis (Mtb) infection is difficult to treat because Mtb spends the majority of its life cycle in a nonreplicating (NR) state. Since NR Mtb is highly tolerant to antibiotic effects and can mutate to become drug resistant (DR), our conventional tuberculosis (TB) treatment is not effective. Thus, a novel strategy to kill NR Mtb is required. Accumulating evidence has shown that repetitive exposure to sublethal doses of antibiotics enhances the level of drug tolerance, implying that NR Mtb is formed by adaptive metabolic remodeling. As such, metabolic modulation strategies to block the metabolic remodeling needed to form NR Mtb have emerged as new therapeutic options. Here, we modeled in vitro NR Mtb using hypoxia, applied isotope metabolomics, and revealed that phosphoenolpyruvate (PEP) is nearly completely depleted in NR Mtb. This near loss of PEP reduces PEP-carbon flux toward multiple pathways essential for replication and drug sensitivity. Inversely, supplementing with PEP restored the carbon flux and the activities of the foregoing pathways, resulting in growth and heightened drug susceptibility of NR Mtb, which ultimately prevented the development of DR. Taken together, PEP depletion in NR Mtb is associated with the acquisition of drug tolerance and subsequent emergence of DR, demonstrating that PEP treatment is a possible metabolic modulation strategy to resensitize NR Mtb to conventional TB treatment and prevent the emergence of DR.

Proceedings of the National Academy of Sciences of the United States of America published new progress about Drug tolerance. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Deliang published the artcileThermodynamics-based model construction for the accurate prediction of molecular properties from partition coefficients, Safety of n-Octanol, the main research area is computational chem linear free energy relationship mol properties; noncovalent interaction partition coefficient quant structure properties; computational chemistry; linear free energy relationships; molecular properties; noncovalent interactions; partition coefficient; quantitative structure-property relationships.

Developing models for predicting mol. properties of organic compounds is imperative for drug development and environmental safety; however, development of such models that have high predictive power and are independent of the compounds used is challenging. To overcome the challenges, we used a thermodn.-based theor. derivation to construct models for accurately predicting mol. properties. The free energy change that determines a property equals the sum of the free energy changes (ΔGFs) caused by the factors affecting the property. By developing or selecting mol. descriptors that are directly proportional to ΔGFs, we built a general linear free energy relationship (LFER) for predicting the property with the mol. descriptors as predictive variables. The LFER can be used to construct models for predicting various specific properties from partition coefficients Validations show that the models constructed according to the LFER have high predictive power and their performance is independent of the compounds used, including the models for the properties having little correlation with partition coefficients The findings in this study are highly useful for applications in drug development and environmental safety.

Frontiers in Chemistry (Lausanne, Switzerland) published new progress about Drug discovery. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Safety of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Deshmukh, Sandip published the artcileEffects of using alcohols on the performance and emissions of a diesel engine, Application In Synthesis of 111-87-5, the main research area is alc diesel engine greenhouse gas emission.

Addition of renewable alcs. to diesel is being investigated extensively to reduce greenhouse gas emissions. The objective of this study was to examine the suitability of such renewable alcs. In this study, emissions and performance characteristics of alc./diesel blends were evaluated for a four stroke single cylinder diesel engine test rig. n-octanol and nbutanol were the alcs. considered. Experiments were conducted at different loads up to 4 kW and for alc. contents from 10% to 40% by volume The results indicated that the alc./diesel blends exhibited similar performance characteristics to that possessed by diesel. A slight drop in brake power was observed in all the blends compared to pure diesel. The brake thermal efficiency and brake specific fuel consumption increased in all alc. blends at almost all the loads considered in the study. The emission anal. was also conducted using the AVL DI Test. The results revealed that CO and NO emissions decreased compared to pure diesel. However, HC emissions increased for n-butanol blends but they decreased in case of n-octanol blends. Results are a clear indication that these blends have an excellent potential and detailed investigations in real life conditions can lead to com. usage.

Journal of Physics: Conference Series published new progress about Diesel engines. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application In Synthesis of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nebesny, Ewa published the artcileEffect of lecithin concentration on properties of sucrose-free chocolate masses sweetened with isomalt, SDS of cas: 64519-82-0, the main research area is lecithin isomalt chocolate food rheol.

Rheol. properties such as Casson viscosity and yield value strongly affect costs and efficiency of the chocolate making process. The addition of a proper amount of lecithin to the blend of chocolate ingredients results in a decrease of both the aforementioned parameters. However, overdosing of lecithin leads to worse sensory attributes and flow properties of the chocolate mass. These studies on rheol. properties of isomalt-containing dark chocolate masses and sucrose-containing milk chocolate masses revealed that the critical lecithin concentration was 0.9 g/100 g; and the Casson yield value of both the types of chocolate blends was enhanced above this content. The same phenomenon, i.e. chocolate thickening, was observed at lecithin concentrations of 0.4 g/100 g and 0.6 g/100 g for milk chocolate masses sweetened with isomalt, and for dark chocolate masses sweetened with sucrose, resp.

European Food Research and Technology published new progress about Dark chocolate. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, SDS of cas: 64519-82-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts