Author: tianli

COA of Formula: C8H10O2. Authors Yamamoto, Y; Ota, M; Kodama, S; Michimoto, K; Nomoto, A; Ogawa, A; Furuya, M; Kawakami, K in AMER CHEMICAL SOC published article about in [Yamamoto, Yuki; Ota, Miyuto; Kodama, Shintaro; Michimoto, Kazuki; Nomoto, Akihiro; Ogawa, Akiya] Osaka Prefecture Univ, Grad Sch Engn, Dept Appl Chem, Sakai, Osaka 5998531, Japan; [Furuya, Mitsunori; Kawakami, Kiminori] Mitsubishi Chem Corp, Sci & Innovat Ctr, Yokohama, Kanagawa 2278502, Japan in 2021, Cited 67. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5

A green method for the oxidation of alcohols to carboxylic acids was developed using a novel co-catalytic system based on gold, silver, and copper catalysts. This reaction system was conducted under atmospheric oxygen in water and mild conditions to selectively oxidize 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid, as a building block for polyethylene furanoate, which is a 100% bio-based, future alternative to the petroleum-based polyethylene terephthalate. Furthermore, various primary alcohols were conveniently oxidized to their corresponding carboxylic acids in up to quantitative yields.

Welcome to talk about 105-13-5, If you have any questions, you can contact Yamamoto, Y; Ota, M; Kodama, S; Michimoto, K; Nomoto, A; Ogawa, A; Furuya, M; Kawakami, K or send Email.. COA of Formula: C8H10O2

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An article Real-World Data on Osimertinib in Chinese Patients with Pretreated, EGFR T790M Mutation Positive, Advanced Non-Small Cell Lung Cancer: A Retrospective Study WOS:000621647300001 published article about GROWTH-FACTOR RECEPTOR; 1ST-LINE TREATMENT; BRAIN METASTASES; OPEN-LABEL; PHASE-II; RESISTANCE; CHEMOTHERAPY; GEFITINIB; ERLOTINIB; MULTICENTER in [Peng, Da; Dai, Chengcheng; Wang, Zifan; Huang, Ziyi; Peng, Rui; Ma, Xuezhen] Qingdao Univ, Affiliated Qingdao Cent Hosp, Dept Oncol, 127 Siliunan Rd, Qingdao 266042, Shandong, Peoples R China; [Shan, Dongfeng] Qingdao Univ, Affiliated Hosp, Qingdao, Shandong, Peoples R China; [Li, Jie] Jiaozhou Cent Hosp, Dept Oncol, Jiaozhou, Peoples R China; [Zhao, Peng] Qingdao Univ, Affiliated Qingdao Cent Hosp, Biotherapy Ctr, Qingdao, Shandong, Peoples R China in 2021, Cited 25. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Formula: C8H10O2

Purpose: As a third-generation EGFR TKI has been taken orally, Osimertinib effectively inhibits mutant EGFR, including T790M EGFR resistance mutations. Here, we examined real-world efficacy and tolerability of Osimertinib among Chinese patients with advanced EGFR T790M-mutant NSCLC. Patients and Methods: A total of 106 advanced NSCLC patients who were taking Osimertinib following disease progression after EGFR-TKIs or other treatments were retro-spectively recruited in this study. The PFS and OS after Osimertinib treatment were analyzed as the primary endpoints. Results: Osimertinib was used as a second line and >= 3rd line treatment in 22.6% and 77.4% of the patients, respectively. DCR and ORR were 93.4% and 57.5%, respectively. Median PFS was 12.4 12 (95% CI, 10.5-13.5) months. The PFS was 11 (8.0, 14.0) and 12 (10.3,13.7) months (p = 0.373), in patients with and without CNS metastasis, respectively. PFS in 2nd and >= 3rd line treatment was 11 (9.0, 13.0) and 12.4 12 (8.9, 15.1) months (p = 0.799), respectively. In patients with EGFR exon 19 deletion and exon 21 L858 mutation, the median PFS was 11 (9.2, 12.8) and 12 (9.2, 14.8) months, respectively (p = 0.833). Median PFS in the monotherapy group and combined anti-angiogenesis group was 11 (9.9,12.1) and 14 (11.2,16.8) months, respectively. Median OS after Osimertinib initiation was 27 (19.6, 34.4) months: 15 (6.9, 23.1) and 27 (22, 32) months in patients with and without CNS metastasis (p=0.027), 27 (20.3,33.7) months and (undefined) as second line or >= 3rd line of treatment (p = 0.421), respectively. In patients with exon 19 deletion, the median OS was not reached, and in patients with exon 21 L858 mutations, the median OS was 23 (19.1,29.9) months (p=0.027). Median OS in the monotherapy group was 27 (21.7,32.3) months, and in combined anti-angiogenesis group was not reached (p=0.68). Conclusion: Osimertinib can effectively treat advanced NSCLC with T790M mutations independently of previous treatment lines.

Formula: C8H10O2. Welcome to talk about 105-13-5, If you have any questions, you can contact Peng, D; Shan, DF; Dai, CC; Li, J; Wang, ZF; Huang, ZY; Peng, R; Zhao, P; Ma, XZ or send Email.

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Application In Synthesis of (4-Methoxyphenyl)methanol. Authors Xia, YY; Lv, QY; Yuan, H; Wang, JY in SPRINGER INTERNATIONAL PUBLISHING AG published article about in [Xia, Yu-Yan; Lv, Qing-Yang; Yuan, Hua; Wang, Jia-Yi] Wuhan Inst Technol, Minist Educ, Key Lab Green Chem Proc, Wuhan 430073, Peoples R China in 2021, Cited 46. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5

An efficient method for catalyzing the ammoxidation of aromatic alcohols to aromatic nitriles was developed, in which a new heterogeneous catalyst based on transition metal elements was employed, the new catalyst was named Co-[Bmim]Br/C-700 and then characterized by X-ray photo-electronic spectroscopy, transmission electron microscope and X-ray diffraction. The reaction was carried out by two consecutive dehydrogenations under the catalysis of Co-[Bmim]Br/C-700, which catalytically oxidized the alcohol to the aldehyde, and then the aldehyde was subjected to ammoxidation to the nitrile. The catalyst system was suitable for a wide range of substrates and nitriles obtained in high yields, especially, the conversion rate of benzyl alcohol, 4-methoxybenzyl alcohol, 4-chlorobenzyl alcohol and 4-nitrobenzyl alcohol reached 100%. The substitution of ammonia and oxygen for toxic cyanide to participate in the reaction accords with the theory of green chemistry.

Welcome to talk about 105-13-5, If you have any questions, you can contact Xia, YY; Lv, QY; Yuan, H; Wang, JY or send Email.. Application In Synthesis of (4-Methoxyphenyl)methanol

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SDS of cas: 105-13-5. Malatinec, S; Bednarova, E; Tanaka, H; Kotora, M in [Malatinec, Stefan; Bednarova, Eva; Tanaka, Hiroki; Kotora, Martin] Charles Univ Prague, Fac Sci, Dept Organ Chem, Chem, Albertov 6, Prague 12843 2, Czech Republic; [Tanaka, Hiroki] Okayama Univ, Res Inst Interdisciplinary Sci, Kita Ku, 3-1-1 Tsushimanaka, Okayama 7008530, Japan published Highly Enantioselective Ring-Opening of meso-Epoxides with O- and N-Nucleophiles Catalyzed by a Chiral Sc(III)/bipyridine Complex in 2021, Cited 52. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5.

The ring-opening of epoxides is a synthetically significant process widely applied in all kinds of chemistry. Herein, we report the catalytic and highly enantioselective variant of this reaction exploiting our recent endeavors to design and synthesize chiral bipyridine type ligands. A Sc-complex with a newly developed bipyridine ligand exhibited high reactivity and stereocontrol in the desymmetrization of meso-epoxides with various alcohols. The respective enantiomerically enriched 1,2-alkoxyalcohols were obtained with e.r. values of up to 99.5:0.5 for various alcohols regardless of their nature (benzyl, alkyl, cycloalkyl, allyl, propargyl, etc.). We attempted ring-opening of meso-epoxides with anilines as well; however, it proceeded with lower enantioselectivity and was strongly depended on the electronic effect of substituents attached to the aromatic ring.

SDS of cas: 105-13-5. Bye, fridends, I hope you can learn more about C8H10O2, If you have any questions, you can browse other blog as well. See you lster.

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An article Role of dietary carbohydrates on risk of lung cancer WOS:000644431300012 published article about GROWTH-FACTOR-I; GLYCEMIC LOAD; SCREENING TRIAL; MEAT MUTAGENS; HEME IRON; PROSTATE; INDEX; INSULIN; VALUES; FIBER in [Tao, Jun; Lam, Wendy W. T.; Pang, Herbert] Univ Hong Kong, Li Ka Shing Fac Med, Sch Publ Hlth, Hong Kong, Peoples R China; [Jatoi, Aminah] Mayo Clin, Dept Oncol, Rochester, MN USA; [Crawford, Jeffrey] Duke Univ, Med Ctr, Duke Canc Inst, Durham, NC USA; [Ho, James C.] Univ Hong Kong, Li Ka Shing Fac Med, Dept Med, Hong Kong, Peoples R China; [Wang, Xiaofei; Pang, Herbert] Duke Univ, Sch Med, Dept Biostat & Bioinformat, Durham, NC USA; [Lam, Wendy W. T.] Univ Hong Kong, Jockey Club Inst Canc Care, Hong Kong, Peoples R China in 2021, Cited 53. COA of Formula: C8H10O2. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5

Objectives: Inconsistent findings have been reported on the link between dietary carbohydrates and lung cancer. This study aims to comprehensively evaluate the role of dietary carbohydrates on lung cancer risk. Materials and methods: The prospective study is based on the PLCO trial, which recruited 113,096 eligible participants across the United States. Participants had to have completed baseline and diet history questionnaires. The incidence of lung cancer was acquired through self-report and medical record follow-up. A multivariable logistic model adjusted for confounders was used to estimate odds ratios (ORs) and 95 % confidence intervals (CIs) of dietary carbohydrates, fiber, whole grains, glycemic index (GI) and glycemic load (GL) for lung cancer. Similar methods were applied in analyzing the carbohydrates and fiber from different food sources. Multinomial logistic models were used for sensitivity analysis with lung cancer subtypes as outcomes. Results: Dietary carbohydrates and GL were inversely associated with lung cancer incidence in the PLCO population. Among various carbohydrates, 30-g daily consumption of dietary fiber was related to a lower risk of lung cancer (fourth vs first quartile OR: 0.62, 95 % CI: 0.54-0.72) compared with 8.8-g. Furthermore, consuming whole grains 2.3 servings per day as opposed to 0.3 servings per day was associated with a lower risk of lung cancer (OR: 0.73, 95 % CI: 0.64-0.83). A higher risk of lung cancer was seen for the consumption of high-GI food (OR: 1.19, 95 % CI: 1.05?1.35) and refined carbohydrates from soft drinks (OR: 1.23, 95 % CI: 1.04?1.46). Conclusion: Carbohydrates and fiber from fruits, vegetables and whole grains are associated with lower lung cancer risk. Refined carbohydrates from processed food, such as soft drinks, appear to increase risk.

COA of Formula: C8H10O2. Bye, fridends, I hope you can learn more about C8H10O2, If you have any questions, you can browse other blog as well. See you lster.

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I found the field of Chemistry very interesting. Saw the article OH/Na co-functionalized carbon nitride: directional charge transfer and enhanced photocatalytic oxidation ability published in 2020. Recommanded Product: 105-13-5, Reprint Addresses Sun, YJ (corresponding author), Chongqing Technol & Business Univ, Coll Environm & Resources, Chongqing Key Lab Catalysis & New Environm Mat, Chongqing 400067, Peoples R China.; Sun, YJ (corresponding author), Univ Elect Sci & Technol China, Inst Fundamental & Frontier Sci, Res Ctr Environm Sci & Technol, Chengdu 611731, Peoples R China.. The CAS is 105-13-5. Through research, I have a further understanding and discovery of (4-Methoxyphenyl)methanol

Graphitic carbon nitride (g-C3N4, CN for short) is a compelling visible-light responsive photocatalyst. However, its photocatalytic efficiency is low due to the random carrier transfer in planes and insufficient redox potential. Herein, we build oxygen functional group modified sodium-doped carbon nitride (OH/Na co-functionalized carbon nitride) to promote directional transfer of charge carriers for acceleration of separation and enhance redox potential for efficient oxidation of NO in air. Specifically, the function of sodium atoms could control the directional transfer of random carriers from the intralayer to the oxygen functional group-modified surface for the purpose of effectively reducing photogenerated electron-hole recombination. Meanwhile, the modification by oxygen-containing functional groups could adjust the band structure of CN, thereby increasing the oxidation-reduction potential of NO in the photocatalyst. The transformation pathways and reaction mechanism of photocatalytic NO oxidation on CN and OH/Na co-functionalized carbon nitride have also been explicated by ESR spectroscopy and in situ DRIFTS and compared. This work provides a new method for simultaneously controlling the random transfer of carriers and adjusting the energy band structure of CN to optimize its photocatalytic efficiency. It is also possible to extend this strategy to improve the performance of other 2D layered catalysts for photocatalytic oxidation.

Welcome to talk about 105-13-5, If you have any questions, you can contact Wang, JD; Cui, W; Chen, RM; He, Y; Yuan, CW; Sheng, JP; Li, JY; Zhan, YX; Dong, F; Sun, YJ or send Email.. Recommanded Product: 105-13-5

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Recommanded Product: (4-Methoxyphenyl)methanol. Authors Epifanov, M; Mo, JY; Dubois, R; Yu, H; Sammis, GM in AMER CHEMICAL SOC published article about in [Epifanov, Maxim; Mo, Jia Yi; Dubois, Rudy; Yu, Hao; Sammis, Glenn M.] Univ British Columbia, Dept Chem, Columbia, BC V6T 1Z1, Canada in 2021, Cited 48. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5

Sulfuryl fluoride is a valuable reagent for the one-pot activation and derivatization of aliphatic alcohols, but the highly reactive alkyl fluorosulfate intermediates limit both the types of reactions that can be accessed as well as the scope. Herein, we report the SO2F2-mediated alcohol substitution and deoxygenation method that relies on the conversion of fluorosulfates to alkyl halide intermediates. This strategy allows the expansion of SO2F2-mediated one-pot processes to include radical reactions, where the alkyl halides can also be exploited in the one-pot deoxygenation of primary alcohols under mild conditions (52-95% yield). This strategy can also enhance the scope of substitutions to nucleophiles that are previously incompatible with one-pot SO2F2-mediated alcohol activation and enables substitution of primary and secondary alcohols in 54-95% yield. Chiral secondary alcohols undergo a highly stereospecific (90-98% ee) double nucleophilic displacement with an overall retention of configuration.

Recommanded Product: (4-Methoxyphenyl)methanol. Bye, fridends, I hope you can learn more about C8H10O2, If you have any questions, you can browse other blog as well. See you lster.

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Computed Properties of C8H10O2. Authors Huang, M; Li, YW; Lan, XB; Liu, JH; Zhao, CY; Liu, Y; Ke, ZF in ROYAL SOC CHEMISTRY published article about in [Huang, Ming] Guangdong Pharmaceut Univ, Sch Clin Pharm, Affiliated Hosp 1, Clin Pharm, Guangzhou 510006, Peoples R China; [Huang, Ming; Li, Yinwu; Lan, Xiao-Bing; Liu, Jiahao; Zhao, Cunyuan; Ke, Zhuofeng] Sun Yat Sen Univ, Sch Chem, PCFM Lab, Sch Mat Sci & Engn, Guangzhou 510275, Peoples R China; [Liu, Yan] Guangdong Univ Technol, Sch Chem Engn & Light Ind, Guangzhou 510006, Peoples R China in 2021, Cited 67. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5

Metal hydride complexes are key intermediates for N-alkylation of amines with alcohols by the borrowing hydrogen/hydrogen autotransfer (BH/HA) strategy. Reactivity tuning of metal hydride complexes could adjust the dehydrogenation of alcohols and the hydrogenation of imines. Herein we report ruthenium(s) complexes with hetero-bidentate N-heterocyclic carbene (NHC)-phosphine ligands, which realize smart pathway selection in the N-alkylated reaction via reactivity tuning of IRu-H) species by hetero-bidentate ligands. In particular, complex 6cb with a phenyl wingtip group and BArr counter anion, is shown to be one of the most efficient pre-catalysts for this transformation (temperature is as low as 70 degrees C, neat conditions and catalyst loading is as low as 0.25 mol%). A large variety of (hetero)aromatic amines and primary alcohols were efficiently converted into mono-N-alkylated amines in good to excellent isolated yields. Notably, aliphatic amines, challenging methanol and diamines could also be transformed into the desired products. Detailed control experiments and density functional theory (DFT) calculations provide insights to understand the mechanism and the smart pathway selection via [Ru-H] species in this process.

Computed Properties of C8H10O2. Welcome to talk about 105-13-5, If you have any questions, you can contact Huang, M; Li, YW; Lan, XB; Liu, JH; Zhao, CY; Liu, Y; Ke, ZF or send Email.

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In 2021 POLYHEDRON published article about ONE-POT SYNTHESIS; SELECTIVE ALKYLATION; EFFICIENT; COMPLEX; ANILINES; SUBSTITUTION; OXIDATION; AMIDES in [Feng, Xinshu; Huang, Ming] Guangdong Pharmaceut Univ, Sch Clin Pharm, Guangzhou 510006, Peoples R China in 2021, Cited 40. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Recommanded Product: 105-13-5

A series of air-stable N-heterocyclic carbene (NHC) Ir(III) complexes (Ir1-6), bearing various combinations of chlorine, pyridine and NHC ligands, were assayed for the N-alkylation of amines with alcohols. It was found that Ir3, with two monodentate 1,3-bis-methyl-imidazolylidene (IMe) ligands, emerged as the most active complex. A large variety of amines and primary alcohols were efficiently converted into mono-N-alkylated amines in 53-96% yields. As a special highlight, for the challenging MeOH, selective N-monomethylation could be achieved using KOH as a base under an air atmosphere. Moreover, this catalytic system was successfully applied to the gram-scale synthesis of some valuable compounds. (C) 2021 Elsevier Ltd. All rights reserved.

Recommanded Product: 105-13-5. Welcome to talk about 105-13-5, If you have any questions, you can contact Feng, XS; Huang, M or send Email.

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In 2021 APPL ORGANOMET CHEM published article about ONE-POT SYNTHESIS; HETEROCYCLIZATION SYNTHESIS; NITROGEN-HETEROCYCLES; 3-COMPONENT SYNTHESIS; PURINE DERIVATIVES; AEROBIC OXIDATION; EFFICIENT; ALCOHOLS; ALDEHYDES; 1,3,5-TRIAZINES in [Debnath, Pradip] Maharaja Bir Bikram Coll, Dept Chem, Agartala 799004, Tripura, India; [Sahu, Gouranga] Ramkrishna Mahavidyalaya, Dept Chem, Unakoti, India; [De, Utpal C.] Tripura Univ, Dept Chem, Agartala, India in 2021, Cited 96. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Name: (4-Methoxyphenyl)methanol

A dehydrogenative coupling of N-uracil amidines with (hetero)aryl methanols has been developed, allowing for the facile synthesis of a broad range of structurally diverse pyrimidouracils. By applying [RuCl2(p-cymene)](2)/Cs2CO3 as an efficient catalytic system, the easily available, cheap (hetero)aryl methanols were firstly employed for oxidative insertion/C-H amination into the N-uracil amidines, providing highly functionalized pyrimido[4,5-d]pyrimidine-2,4-diones. Due to the better stability of alcohols than aldehydes, this synthetic protocol is applicable to a broad range of alcoholic substrates and does not required any protection during the whole preparation process. The presented protocol has the potential to prepare valuable products which cannot be accessed presently or extremely arduous to procure by following regular procedure. Hence, this is a remarkably improved protocol compared with the existing methodologies. The overall reaction sequence is an effective oxidation-imination-cyclization tandem process catalyzed by ruthenium catalyst.

Bye, fridends, I hope you can learn more about C8H10O2, If you have any questions, you can browse other blog as well. See you lster.. Name: (4-Methoxyphenyl)methanol

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