Author: tianli

Willems, Suzanne; Toupalas, Georgios; Reisenbauer, Julia C.; Morandi, Bill published the artcile< A site-selective and stereospecific cascade Suzuki-Miyaura annulation of alkyl 1,2-bisboronic esters and 2,2'-dihalo 1,1'-biaryls>, Computed Properties of 627-27-0, the main research area is dihydrophenanthrene preparation regioselective; bisboronic ester biaryl Suzuki Miyaura annulation cascade palladium catalyst.

A cascade Suzuki-Miyaura cross-coupling gave rise to 9,10-dihydrophenanthrenes I [R1 = n-Pr, n-hexyl, (CH2)2Ph, etc.; R2 = H, 3-Me, 2-F, etc.; R3 = H, 6-Me, 7-F, etc.] was developed. Using biaryls with unsym. substitution-pattern full site-selectivity was observed Furthermore, this cross-coupling of an alkyl 1,2-bisboronic pinacol ester proceeded through the challenging coupling of a secondary boronate with complete stereoretention.

Chemical Communications (Cambridge, United Kingdom) published new progress about Biaryls Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Computed Properties of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kondo, Mizuho; Miyake, Jun-ichi; Tada, Kazuya; Kawatsuki, Nobuhiro published the artcile< Tuning photoluminescent wavelength of water-soluble oligothiophene/polymer complex film by proton bonding>, Reference of 660867-80-1, the main research area is thiophene oligomer pyridyl end group preparation photoluminescence photochromism protonation.

An oligothiophene derivative with pyridine end groups was prepared and the UV-visible absorption and photoluminescence of the compound were studied. Upon addition of aqueous polystyrenesulfonic acid solution, homogeneous complex films with protonated structure were observed Reversible color change in photoluminescence, in response to exposure of the protonated species to base solution was observed, which is due to reversible protonation of pyridyl end groups; this response can be applied to acid sensors.

Chemistry Letters published new progress about Luminescence. 660867-80-1 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H18BNO2, Reference of 660867-80-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Huang, Xu-Hui; Qi, Li-Bo; Fu, Bao-Shang; Chen, Zeng-Hui; Zhang, Yu-Ying; Du, Ming; Dong, Xiu-Ping; Zhu, Bei-Wei; Qin, Lei published the artcile< Flavor formation in different production steps during the processing of cold-smoked Spanish mackerel>, Safety of 2-Ethylhexan-1-ol, the main research area is mackerel flavor smoking; Cold smoking; Flavor formation; GC–MS; Mackerel; P&T; e-Nose.

This study aimed to determine the changes in the flavor profile during different operating units when making cold-smoked Spanish mackerel. Sensory evaluation and instrumental anal. of tenderness were applied to optimize the processing parameters. For the overall odor perception, distinct odor among fresh and processed samples could be distinguished using electronic nose (e-Nose). Purge-and-trap (P&T) extraction combined with gas chromatog.-mass spectrometry (GC-MS) was used to identify volatile compounds Alcs. were the major volatiles in Spanish mackerel over the whole processing, while 2-butanol was found in the highest concentration Curing was an effective way to remove fishy odor. Drying decreased the concentration of volatiles, especially sulfur compounds Odor formation in cold-smoked mackerel could be divided into four steps (curing, drying, cold smoking and heating) as a result of partial least squares discriminant anal. (PLS-DA).

Food Chemistry published new progress about Flavor. 104-76-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H18O, Safety of 2-Ethylhexan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Xiaolei; Guo, Feng; Tian, Peng; Yu, Shuangen; Xue, Chun-Xu; Wang, Wei; Xiao, Jiaguang; Niu, Wentao published the artcile< Flammeovirga agarivorans sp. nov., an agar-digesting marine bacterium isolated from surface seawater>, Electric Literature of 87-73-0, the main research area is Flammeovirga agarivorans agar digesting marine bacterium surface seawater; Flammeovirga agarivorans sp. nov.; Luhuitou fringing reef; surface seawater.

A Gram-stain-neg., aerobic, gliding, reddish-orange-colored, rod-shaped strain, designated SR4T, was isolated from surface seawater sampled at Luhuitou fringing reef (South China Sea). Phylogenetic analyses based on the 16S rRNA gene, phylogenomic anal. of single-copy gene families and whole genome data affiliated it to the genus Flammeovirga. It was most closely related to Flammeovirga yaeyamensis NBRC 100898T (97.99% 16S rRNA gene similarity). The genome average nucleotide identity and DNA-DNA relatedness values between strain SR4T and its reference strains were less than 74.2 and 16.3%, resp. Growth occurred at 20-35° (optimum, 28°), pH 6.0-9.0 (optimum, pH 7.0) and in the presence of 1-6% (w/v) NaCl (optimum, 2-4%). The dominant fatty acids were C16 : 0, iso-C15 : 0 and C20 : 4 ω 6,9,12,15c. The polar lipid profile of strain SR4T comprised phosphatidylethanolamine, two glycolipids, two aminophospholipids and three unidentified lipids. The major respiratory quinone was MK-7. The DNA G + C content of strain SR4T was 34.20 mol%. On the basis of the polyphasic evidence, strain SR4T is proposed as representing a novel species of the genus Flammeovirga, for which the name Flammeovirga agarivorans sp. nov. is proposed. The type strain is SR4T (= KCTC 82075T = MCCC 1A17137T).

International Journal of Systematic and Evolutionary Microbiology published new progress about 16S rRNA Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Electric Literature of 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nuerxiati, Rehebati; Abuduwaili, Aytursun; Mutailifu, Paiheerding; Wubulikasimu, Atikan; Rustamova, Nigora; Cui, Jingxue; Aisa, Haji Akber; Yili, Abulimiti published the artcile< Optimization of ultrasonic-assisted extraction, characterization and biological activities of polysaccharides from Orchis chusua D. Don (Salep)>, SDS of cas: 3458-28-4, the main research area is polysaccharide Orchis chusua biol activity ultrasonic assisted extraction; Biological activity; Characterization; Optimization; Orchis chusua D. Don polysaccharide; Ultrasonic-assisted extraction.

In the present study, ultrasonic-assisted extraction (UAE) of polysaccharides from Orchis chusua D. Don (salep) was optimized by response surface methodol. (RSM) combined with a Box-Behnken design (BBD), the optimum conditions were determined to be: ultrasonic power of 390 W, extraction temperature of 60°C, extraction time of 50 min and water/raw material ratio of 40 mL/g. Based on it, 48.30 ± 0.6% yield of crude polysaccharide was obtained. After purification, the chem. compositions, physicochem. and structural property was investigated based on the GC-MS, TGA, XRD, SEM and Congo red test. The results showed that USP-U and USP-N were hetero-polysaccharides, mainly composed of mannose and glucose, and the average mol. weight was 25.57 kDa and 11.64 kDa, resp. FT-IR spectra and NMR results indicated that the presence of a-linkage glycopyranose via typical peaks. Furthermore, reducing power and antioxidant activities of both purified fractions showed a relatively high ability to scavenge free radicals. Lastly, the cytotoxicity assay showed that purified polysaccharides have no obvious cytotoxicity against RAW267.4 and L6 cells at their effective concentration and had potent anti-inflammatory activity in a concentration-dependent manner. Salep polysaccharide is expected to be developed as a new efficacy factor in the pharmaceutical and food industry.

International Journal of Biological Macromolecules published new progress about Composition. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, SDS of cas: 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Luo, Yitao; Zhang, Chengqiang; Ma, Li; Zhang, Yuxiao; Liu, Zhengyuan; Chen, Li; Wang, Rui; Luan, Yujing; Rao, Yulan published the artcile< Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome>, COA of Formula: C27H44O, the main research area is Smith Lemli Opitz syndrome hair diagnosis 7 dehydrocholesterol cholesterol; diagnostic test; gas chromatography-mass spectrometry; hair analysis; micro-pulverized extraction; microwave-assisted derivatization.

7-Dehydrocholesterol (7-DHC) and cholesterol (CHOL) are biomarkers of Smith-Lemli-Opitz Syndrome (SLOS), a congenital autosomal recessive disorder characterized by elevated 7-DHC level in patients. Hair samples have been shown to have great diagnostic and research value, which has long been neglected in the SLOS field. In this study, we sought to investigate the feasibility of using hair for SLOS diagnosis. In the presence of antioxidants (2,6-ditert-butyl-4-methylphenol and triphenylphosphine), hair samples were completely pulverized and extracted by micro-pulverized extraction in alk. solution or in n-hexane. After microwave-assisted derivatization with N,O-Bis(trimethylsilyl)trifluoroacetamide, the analytes were measured by GC-MS. We found that the limits of determination for 7-DHC and CHOL were 10 ng/mg and 8 ng/mg, resp. In addition, good linearity was obtained in the range of 50-4000 ng/mg and 30-6000 ng/mg for 7-DHC and CHOL, resp., which fully meets the requirement for SLOS diagnosis and related research. Finally, by applying the proposed method to real hair samples collected from 14 healthy infants and two suspected SLOS patients, we confirmed the feasibility of hair anal. as a diagnostic tool for SLOS. In conclusion, we present an optimized and validated anal. method for the simultaneous determination of two SLOS biomarkers using human hair.

Journal of Lipid Research published new progress about Antioxidants. 434-16-2 belongs to class alcohols-buliding-blocks, and the molecular formula is C27H44O, COA of Formula: C27H44O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Guoqi; Li, Sihan; Zeng, Haisu; Zheng, Shengping; Neary, Michelle C. published the artcile< Diplumbane-catalysed solvent- and additive-free hydroboration of ketones and aldehydes>, Synthetic Route of 403-41-8, the main research area is alc preparation chemoselective; ketone aldehyde pinacolborane hydroboration diplumbane catalyst.

A new diplumbane, namely [Pb(CH2SiMe3)3]2, was synthesized and structurally characterized. This group 14 element compound was found to catalyze the hydroboration of ketones R1C(O)R2 (R1 = Ph, 4-fluorophenyl, naphthalen-2-yl, pyridin-3-yl, cyclohexyl, etc.; R2 = H, Me, cyclopropyl, 2-phenylethyl) and aldehydes R3CHO (R3 = Ph, 4-chlorophenyl, 2H-1,3-benzodioxol-5-yl, 2-(methylsulfanyl)phenyl, etc.) under mild conditions without the use of additives and solvents, leading to the synthesis of a range of alcs. R1CH(OH)R2/R3CH2OH in high yields after hydrolysis.

RSC Advances published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Synthetic Route of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Abdullayev, Yusif; Ahmadov, Orkhan; Valadova, Gunay; Karimli, Ayan; Autschbach, Jochen published the artcile< Unveiling the catalytic effects of Bronsted acidic ionic liquid on quantitative α-glucose conversion to 5-HMF: Experimental and computational studies>, Synthetic Route of 492-62-6, the main research area is glucose Bronsted acidic ionic liquid dehydration mechanism.

Effective biomass conversion to 5-HMF(5-hydroxymethylfurfural) is still a challenge and needs to be improved because of the 5-HMF importance as building blocks for valuable monomers and fuel precursors. We suggest for the first time utilization of low-cost metal-free Bronsted acidic Ionic liquid (IL) N,N-Diethyl-1,4-phenylenediamine hydrogen sulfate, [DPhDA]HSO4 as a catalyst for the α-glucose dehydration to 5-HMF. Quant. α-glucose conversion is achieved via optimizing the reaction condition: 91.4% 5-HMF yield with 30 mol% [DPhDA]HSO4 in the presence of DMSO as a solvent at 160°C in 30 min (TOF 6.1 h-1). 3-fold increase in reaction time leads to higher (94%) 5-HMF yield at 160°C with lower TOF 1.6 h-1. The IL surprising catalytic performance is scrutinized with its amphiprotic nature (availability of basic and acidic spots in its structure (Fig. 1)). Further computational mechanistic studies revealed the function of the catalytic sites in the α-glucose dehydration. We calculated five-membered ring formation and water extrusion in one concerted transition state (TS2A, ΔG‡ = 38.8 kcal/mol) following the α-glucose ring-opening (TS1, ΔG‡ = 20.4 kcal/mol). Further four steps (sp3-s, C-H bond cleavages (TS3, TS6) and dehydroxylation (TS4A, TS5)) are quite straightforward to reach the product (5-HMF).

Renewable Energy published new progress about Dehydration reaction. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Synthetic Route of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fischer, Oliver; Heinrich, Markus R. published the artcile< 2-Fluoro-5-nitrophenyldiazonium: A Novel Sanger-Type Reagent for the Versatile Functionalization of Alcohols>, Category: alcohols-buliding-blocks, the main research area is aryl alkoxy nitrobenzenediazonium tetrafluoroborate preparation; alc fluoro nitrophenyldiazonium tetrafluoroborate nucleophilic aromatic substitution; C−C bond formation; C−H activation; Sanger reagent; diazonium; nucleophilic aromatic substitution.

As a novel Sanger-type reagent, 2-fluoro-5-nitrophenyldiazonium tetrafluoroborate enabled the versatile functionalization of primary aliphatic alcs. e.g., β-citronellol and secondary aliphatic alcs. e.g., trans-1,2-cyclohexandiol. Based on a mild nucleophilic aromatic substitution of the fluorine atom under unprecedented, base-free conditions, the diazonium unit on the aromatic core of the resulting aryl-alkyl ether e.g., I could be employed for such diverse transformations as radical C-H activation and cyclization, as well as palladium catalyzed cross-coupling reactions.

Chemistry – A European Journal published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ren, Cheng; Fang, Runxing; Yu, Xiaochun; Wang, Shun published the artcile< A highly efficient reusable homogeneous copper catalyst for the selective aerobic oxygenation of sulfides to sulfoxides>, Recommanded Product: 2-(Phenylthio)ethanol, the main research area is sulfoxide preparation green chem; sulfide aerobic oxidation copper catalyst.

Readily available copper showed efficient activity and great selectivity for the homogeneous catalysis of oxidation of sulfides to sulfoxides using mol. oxygen as the oxidant. The reaction proceeds under mild conditions in the presence of a catalytic amount of TEMPO. Importantly, the catalysts could be conveniently recovered and reused. And this methodol. was proved to be applicable for the transformation of various aromatic and aliphatic sulfides into the corresponding sulfoxides with high conversion and high selectivity.

Tetrahedron Letters published new progress about Green chemistry. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Recommanded Product: 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts