Author: tianli

Zhou, Qingqing; Ye, Man; Ma, Wenbao; Li, Difan; Ding, Bingjie; Chen, Manyu; Yao, Yefeng; Gong, Xueqing; Hou, Zhenshan published the artcile< Ionic Liquid Stabilized Niobium Oxoclusters Catalyzing Oxidation of Sulfides with Exceptional Activity>, Quality Control of 699-12-7, the main research area is ionic liquid stabilized niobium oxocluster catalyzing oxidation sulfide activity; hydrogen peroxide; oxidation; oxoclusters; peroxoniobium species; sulfides.

We present here a new class of niobium oxoclusters that are stabilized effectively by carboxylate ionic liquids These functionalized ILs are designated as [TBA][LA], [TBA][PA], and [TBA][HPA] in this work, in which TBA represents tetrabutylammonium and LA, PA, and HPA refer to lactate, propionate, 3-hydroxypropionate anions, resp. The as-synthesized Nb oxoclusters have been characterized by use of elemental anal., NMR, IR, XRD, TGA, HRTEM. It was found that [TBA][LA]-stabilized Nb oxoclusters (Nb-OC@[TBA][LA]) are uniformly dispersed with an average particle size of 2-3 nm and afforded exceptionally high catalytic activity for the selective oxidation of various thioethers. The turnover number with Nb-OC@[TBA][LA] catalyst was over 56 000 at catalyst loading as low as 0.0033 mol % (1 ppm). Meantime, the catalyst also showed the high activity for the epoxidation of olefins and allylic alcs. by using only 0.065 mol % of catalyst (50 ppm). The characterization of 93Nb NMR spectra revealed that the Nb oxoclusters underwent structural transformation in the presence of H2O2 but regenerated to their initial state at the end of the reaction. In particular, the highly dispersed Nb oxoclusters can absorb a large amount of polar organic solvents and thus were swollen greatly, which exhibited “”pseudo”” liquid phase behavior, and enabled the substrate mols. to be highly accessible to the catalytic center of Nb oxocluster units.

Chemistry – A European Journal published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Quality Control of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pesci, Pierantonio published the artcile< Involvement of chloride in the increase in proline induced by ABA and stimulated by potassium chloride in barley leaf segments>, SDS of cas: 35564-86-4, the main research area is ABA induction proline barley chloride.

Stimulation by NaCl or KCl of the ABA-induced increase in proline was synergistically enhanced by CaCl2 or MgCl2 as well as by 1,3-bis[tris(hydroxymethyl)methylamino]propane chloride (BTP-Cl), N-methyl-D-glucamine chloride (NMG-Cl), or 2-amino-2-hydroxymethyl-1,3-propandiol chloride (TRIS-Cl). This enhancing effect did not depend on the osmolarity and occurred when Cl- was higher than K+ in the incubation medium, but not vice versa. When CaCl2 or MgCl2 or NMG-Cl were added, the higher the Cl-:K+ ratio in the external solution the higher was the increase in proline. When the excess of Cl- to K+ was obtained with BTP-Cl the highest enhancing effect resulted with a Cl-:K+ ratio of 3:1 while, at a 5:1 ratio, the KCl stimulation was completely suppressed. The inhibiting effect of proline accumulation by NH4+ and 4,4′-diisothiocyano-2,2′-disulfonicacid stilbene was reversed to varying degrees depending on the magnitude of the excess of Cl- on K+ concentration in the medium. Also, the inhibition of proline accumulation obtained by tetraethylammonium chloride, monensin, and D-mannose was similarly reverted. Thus, Cl- elicits an increase in ABA-induced proline which requires the simultaneous presence of K+ (or Na+).

Plant Physiology published new progress about Barley. 35564-86-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C7H18ClNO5, SDS of cas: 35564-86-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Moggia, Giulia; Schalck, Jonathan; Daems, Nick; Breugelmans, Tom published the artcile< Two-steps synthesis of D-glucaric acid via D-gluconic acid by electrocatalytic oxidation of D-glucose on gold electrode: Influence of operational parameters>, Electric Literature of 87-73-0, the main research area is synthesis glucaric gluconic acid electrocatalysis oxidation glucose gold electrode.

Glucose electrooxidation to glucaric acid, a highly valuable platform chem., was conducted, for the 1st time, in two consecutive steps employing a bare Au electrode in a batch reactor. The 1st step, at low potential, enabled the effective formation of the intermediate, gluconic acid, promoted by the oxidation of the aldehyde group on C1. For this reaction step, except for the reaction time, all the operational parameters had a strong impact on the selectivity. At the optimal conditions of pH 11.3, 5° and 0.04M initial glucose, a maximum selectivity of 97.6% was obtained, the highest reported to date for the electrochem. process, with a conversion of 25%. At higher potential, gluconic acid was further converted to glucaric acid by the oxidation of the hydroxymethyl group on C6. For this oxidation step, the variation of the operational parameters (pH, gluconic acid initial concentration, reaction temperature and time) had no conspicuous effect on the selectivity, while the applied potential had a major role: at 1.1 VRHE, a maximum selectivity of 89.5% to glucaric acid was obtained, which is one of the highest values reported in literature so far. In all experiments, irresp. of conditions and reaction time, a maximum concentration of ∼1.2 mM of glucaric acid was achieved, and a drastic decrease of the c.d. was observed in the 1st hours of electrolysis. Addnl. control experiments revealed a poisoning process caused by glucaric acid that, once formed, remains strongly bonded to the catalyst’s active sites, thus deactivating it.

Electrochimica Acta published new progress about Cyclic voltammetry. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Electric Literature of 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lu, Jianwu; Shi, Yinfei; Li, Xiao; Liang, Xiaomin; Wang, Yinquan; Yuan, Shun; Wu, Taizhi published the artcile< Understanding and Controlling the Formation of an N-Alkyl Impurity in Olmesartan Medoxomil: A Derivative via Michael-Type Addition between Tetrazole and Mesityl Oxide In Situ Generated from Acetone>, COA of Formula: C19H16O, the main research area is olmesartan medoxomil API impurity quality by design definitive screening.

An unknown impurity was detected in olmesartan medoxomil active pharmaceutical ingredient (API), which was determined as 2-methyl-4-oxopentan-2-yl-protected olmesartan medoxomil by NMR and mass spectrometry (MS). The formation mechanism of this impurity was investigated. In summary, the tetrazole of the final product was condensed with the potential genotoxic compound mesityl oxide generated from acetone self-condensation in acidic conditions to form the N-Alkyl impurity. Further quality control of the reaction was investigated using statistical methods (design of experiment, DoE) via a definitive screening design. The key factors of the reaction were determined to control the process parameters. Three batches of validation experiments showed that the generation of the N-Alkyl impurity was suppressed (<0.1%) and the residual mesityl oxide was not detected (<2.5 ppm). Organic Process Research & Development published new progress about Antihypertensives. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, COA of Formula: C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cui, Jianchao; Ke, Sen; Zhao, Jia; Wu, Shufeng; Luo, Wencheng; Xu, Shinuo; Su, Xiaolong; Li, Yi published the artcile< Photocatalytic access to aromatic keto sulfonyl fluorides from vinyl fluorosulfates>, Reference of 627-27-0, the main research area is aromatic keto sulfonyl fluoride preparation; vinyl fluorosulfate preparation rearrangement iridium photocatalyst.

An efficient photocatalytic transformation of vinyl fluorosulfates I [R = H, 5-Br, 6-Me, 7-(phenanthren-1-yl), etc.; X = -CH2-, -O-, -CH(CH3)-], and 1H-inden-3-yl sulfofluoridate, 6-bromo-1H-inden-3-yl sulfofluoridate to aromatic β-keto sulfonyl fluorides II, III (R = H, Br) with 1 mol% of iridium catalyst under the irradiation of 3 W blue LEDs was presented. Preliminary mechanistic studies proposed a direct radical fragmentation and recombination of vinyl fluorosulfates through a free fluorosulfonyl radical (FSO2). This methodol. provides a facile approach to aromatic β-keto sulfonyl fluorides, featuring sustainable conditions and a broad substrate scope (32 examples) with 33%-90% isolated yields.

Organic Chemistry Frontiers published new progress about Cyclic voltammetry. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Reference of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Comotti, A.; Castiglioni, F.; Bracco, S.; Perego, J.; Pedrini, A.; Negroni, M.; Sozzani, P. published the artcile< Fluorinated porous organic frameworks for improved CO2 and CH4 capture>, SDS of cas: 76-84-6, the main research area is fluoropolymer polyacetylene synthesis adsorbent carbon dioxide methane adsorption.

A porous 3D selectively fluorinated framework (F-PAF1), robust yet flexible and with a surface area of 2050 M2 g-1, was synthesized by condensation of an ad hoc prepared fluorinated tetraphenylmethane (TPM) monomer to ensure homogeneously distributed C-F dipoles in the swellable architecture. Tetradentate TPM was also the comonomer for the reaction with fluorinated difunctional monomers to obtain frameworks (FMFs) with a controlled amount of regularly spaced reorientable C-F dipoles. The isosteric heat of adsorption of CO2 was increased by 53% by even moderate C-F dipole insertion, with respect to the non-fluorinated frameworks. CO2/N2 selectivity was also increased up to a value of 50 for the difluoro-containing comonomer. Moreover, methane shows optimal interaction energies of 24 kJ mol-1.

Chemical Communications (Cambridge, United Kingdom) published new progress about Adsorbents. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, SDS of cas: 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pandey, Bedraj; Xu, Shi; Ding, Keying published the artcile< Switchable β-alkylation of Secondary Alcohols with Primary Alcohols by a Well-Defined Cobalt Catalyst>, Electric Literature of 403-41-8, the main research area is alkylation primary secondary alc preparation cobalt triphosphine pyridine catalyst; switchable ketone secondary alc preparation alkylation benzenemethanol cobalt catalyst.

β-Alkylation of secondary alcs. R1CH(OH)Me with primary alcs. R2CH2OH catalyzed by cobalt(I) triphosphine-pyridine complex in the presence of KOtBu selectively generate either alcs. R1CH(OH)CH2CH2R2 or ketones R1COCH2CH2R2 in dependence of catalyst and base loadings and hydrogen presence or removal. Remarkably, a low catalyst loading of 0.7 mol% can be employed for the reaction. More significantly, this study represents the first Co-catalyzed switchable alc./ketone synthesis by simply manipulating the reaction parameters. In addition, the transformation is environmentally friendly, with water as the only byproduct.

Organometallics published new progress about Alkylation. 403-41-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H9FO, Electric Literature of 403-41-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Baars, Julian; Grimm, Isabelle; Blunk, Dirk; Neudorfl, Jorg-Martin; Schmalz, Hans-Guenther published the artcile< Enantioselective Total Synthesis and Structural Revision of Dysiherbol A>, Recommanded Product: But-3-en-1-ol, the main research area is dysiherbol A enantiomer enantioselective synthesis addition cyclization cyclopropane opening; cyclization; enantioselectivity; gold catalysis; natural products; rearrangement.

A 12-step total synthesis of the natural product dysiherbol A, a strongly anti-inflammatory and anti-tumor avarane meroterpene isolated from the marine sponge Dysidea sp., was elaborated. As key steps, the synthesis features an enantioselective Cu-catalyzed 1,4-addition/enolate-trapping opening move, an Au-catalyzed double cyclization to build up the tetracyclic core-carbon skeleton, and a late installation of the C5-bridgehead Me group via proton-induced cyclopropane opening associated with spontaneous cyclic ether formation. The obtained pentacyclic compound I (corresponding to an anhydride of the originally suggested structure for dysiherbol A) showed identical spectroscopic data as the natural product, but an opposite mol. rotation. CD-spectroscopic measurements finally confirmed that both the constitution and the absolute configuration of the originally proposed structure of (+)-dysiherbol A need to be revised.

Angewandte Chemie, International Edition published new progress about 1,4-Addition reaction catalysts (stereoselective). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sun, Peng-Wei; Zhang, Ze; Wang, Xinyao; Li, Linshan; Li, Yuxin; Li, Zhengming published the artcile< Cobalt-Catalyzed Intermolecular Hydroamination of Unactivated Alkenes Using NFSI as Nitrogen Source>, Application of C4H8O, the main research area is diphenylsulfonimide preparation chemoselective regioselective; alkene fluorobenzenesulfonimide cobalt hydroamination.

Comprehensive Summary : Cheap metal (Fe, Mn, and Co)-catalyzed hydroamination of alkenes has been an attractive method for synthesis of amines because of biocompatibility of metal, excellent Markovnikov selectivity and chemoselectivity. However, most reports are limited to unsaturated nitrogen sources (nitric oxide, azos, azides, cyano, etc.), for which aminated products are very limited. Notably, while used widely for fluorinating reaction, N-fluorobenzenesulfonimide (NFSI) as amine source for hydroamination has seldom been reported. Here authors developed a cobalt-catalyzed intermol. hydroamination of unactivated alkenes using NFSI as nitrogen source under mild conditions. The reaction exhibits excellent chemo- and regio-selectivity with no hydrofluorination or linear-selectivity products. Notably, the reaction proceeded with excellent yield even though the amount of Co(salen) catalyst was reduced to 0.2 mol%. Recently, a similar work was also reported by Zhang and coworkers (reference 19).

Chinese Journal of Chemistry published new progress about Aryl alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Application of C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rodriguez Tzompantzi, Tomasa; Amaro Hernandez, Aldo Guillermo; Meza-Leon, Rosa Luisa; Bernes, Sylvain published the artcile< Deciphering the hydrogen-bonding scheme in the crystal structure of triphenylmethanol: a tribute to George Ferguson and co-workers>, Quality Control of 76-84-6, the main research area is triphenylmethanol crystal structure hydrogen bond; alcohol; crystal structure; disorder; hydrogen bond; topological chirality; triphenylmethanol.

The crystal structure of triphenylmethanol, C19H16O, has been redetermined using data collected at 295 and 153 K, and is compared to the model published by Ferguson et al. over 25 years ago [Ferguson et al. (1992). Acta Crystalline C48, 1272-1275] and that published by Serrano-Gonzalez et al., using neutron and X-ray diffraction data [Serrano-Gonzalez et al. (1999). J. Phys. Chem. B, 103, 6215-6223]. As predicted by these authors, the hydroxy groups are involved in weak intermol. hydrogen bonds in the crystal, forming tetrahedral tetramers based on the two independent mols. in the asym. unit, one of which is placed on the threefold symmetry axis of the R [inline formula omitted] space group. However, the reliable determination of the hydroxy H-atom positions is difficult to achieve, for two reasons. Firstly, a positional disorder affects the full asym. unit, which is split over two sets of positions, with occupancy factors of ca 0.74 and 0.26. Secondly, all hydroxy H atoms are further disordered, either by symmetry, or through a positional disorder in the case of parts placed in general positions. We show that the correct description of the hydrogen-bonding scheme is possible only if diffraction data are collected at low temperature The prochiral character of the hydrogen-bonded tetrameric supramol. clusters leads to enantiomorphic three-dimensional graphs in each tetramer. The crystal is thus a racemic mixture of supS and supR motifs, consistent with the centrosym. nature of the R [inline formula omitted] space group.

Acta Crystallographica, Section C: Structural Chemistry published new progress about Crystal structure. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Quality Control of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts