Month: February 2023

Copper-Catalyzed Asymmetric Borylative Ring Opening of Diazabicycles was written by Lee, Hyesu;Han, Jung Tae;Yun, Jaesook. And the article was included in ACS Catalysis in 2016.COA of Formula: C16H20B2N2O2 This article mentions the following:

Highly enantioselective, copper-catalyzed ring opening of bicyclic hydrazines using a diboron reagent was accomplished with (R,R)-taniaphos as a chiral ligand. Desymmetrization of various bicyclic hydrazines by boryl substitution afforded 3-Bpin-4-hydrazino-cyclopentene derivatives with enantioselectivity up to >99% under mild conditions. The resulting allylic boron products were utilized in further organic transformations. Kinetic resolution of a racemic bicyclic oxazine gave useful information about the relative rates of C-O and C-N bond cleavage. In the experiment, the researchers used many compounds, for example, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6COA of Formula: C16H20B2N2O2).

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.COA of Formula: C16H20B2N2O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dietary Euterpe oleracea Mart. attenuates seizures and damage to lipids in the brain of Colossoma macropomum was written by da Silva, Thamyres V. N.;Torres, Marcelo F.;Sampaio, Luis A.;Hamoy, Moises;Monserrat, Jose M.;Barbas, Luis Andre L.. And the article was included in Fish Physiology and Biochemistry in 2021.Recommanded Product: Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate This article mentions the following:

The Amazonian acai fruit (Euterpe oleracea) has shown promising anticonvulsant properties, comparable to those of diazepam (BDZ) in in vivo models submitted to pentylenetetrazole (PTZ). PTZ is a classic convulsant agent used in studies for the purpose of screening anticonvulsants and investigating the mechanisms of epilepsy. Herein, we aimed to determine, for the first time, the effect of dietary administration of lyophilized E. oleracea (LEO) on PTZ-induced seizures, using juvenile Colossoma macropomum fish (9.1 ±1.5 g) as a model. A control diet (0.00% LEO) and two levels of LEO inclusion were established: 5.00% and 10.0% LEO (weight/weight). Fish were divided into five groups (n = 5): control (0.9% physiol. solution; i.p.), PTZ (PTZ 150 mg kg-1; i.p.), PTZ LEO 5.00%, PTZ LEO 10.0%, and BDZ-PTZ (BDZ: diazepam 10 mg kg-1; i.p.). In addition to the electroencephalog. (EEG), the lipid peroxidation (TBARS) was quantified in the brain, along with the characterization of behavioral responses. Fish receiving PTZ showed intense action potential bursts (APB), which overlapped with a hyperactive behavior. In PTZ LEO 5.00% and 10.0% groups, convulsive behavior was significantly reduced compared to the PTZ group. Fish fed 5.00% or 10.0% LEO and exposed to PTZ showed less excitability and lower mean amplitude in tracings. The inclusion of 10.0% LEO in the diet prevented the increase in mean amplitude of the EEG waves by 80%, without significant differences to the quantified mean amplitude of the BDZ-PTZ group. TBARS concentration was reduced by 60% in the brain of fish fed 10.0% LEO-enriched diets relative to the PTZ-administered group. The results of this study demonstrated the anticonvulsant and protective roles of LEO to the brain, and the dietary inclusion of LEO seems to be promising for the formulation of functional diets. Results of this study may boost the interest on the anti-seizurogenic properties of Euterpe oleracea, including the development of new approaches for the prevention of seizures in humans and animals with low epileptic threshold. In the experiment, the researchers used many compounds, for example, Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6Recommanded Product: Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate).

Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pathogenicity of Aeromonas veronii causing mass mortalities of Odontobutis potamophila and its induced host immune response was written by Liu, Guoxing;Li, Jie;Jiang, Ziyan;Zhu, Xinhai;Gao, Xiaojian;Jiang, Qun;Wang, Jun;Wei, Wanhong;Zhang, Xiaojun. And the article was included in Fish & Shellfish Immunology in 2022.COA of Formula: C4H10O4 This article mentions the following:

Aeromonas veronii is a freshwater bacterium associated with many diseases in aquatic animals. However, few cases of A. veronii infection were reported in Odontobutis potamophila, which has been becoming a promising fish species in China in recent years. In this study, the dominant bacteria were isolated from diseased O. potamophila showing signs of hemorrhage on fins, ulceration on the dorsal and abdomen. The representative isolate Stl3-1was identified as A. veronii based on anal. of its morphol., physiol., and biochem. features, as well as 16S rRNA and gyrB gene sequences. The median lethal dosage (LD₅₀) of the isolate Stl3-1 for O. potamophila was determined as 4.5 x 10⁵ CFU/mL. Histopathol. anal. revealed that the isolate Stl3-1caused considerable histol. lesions in the fish, including tissue cell degeneration, necrosis, and inflammatory cell infiltrating. Detection of virulence-related genes showed that A. veronii Stl3-1 was pos. for exu, ompA, lip, flaH, hlyA, aer, flgM, tapA, act, flgA, gcaT and flgN. Addnl., quantitive real-time PCR (qRT-PCR) was also undertaken to analyzes the host defensive response in O. potamophila infected by A. veronii. The immune-related gene expressions in O. potamophila during exptl. infection were monitored at different point of time, and the results showed that the expression levels of MHC II, Myd88, TLR, and SOD were significantly up-regulated in liver, gill, spleen, and head kidney. The results revealed that A. veronii was a pathogen causing mass mortalities of O. potamophila and will contribute to better understanding the host defensive response against A. veronii infection. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6COA of Formula: C4H10O4).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.COA of Formula: C4H10O4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Heterogeneous asymmetric hydrogenation of aromatic ketones enhanced by silanols on highly monodispersed silica spheres was written by Li, Chun;Zhang, Lin;Liu, Hailong;Zheng, Xueli;Fu, Haiyan;Chen, Hua;Li, Ruixiang. And the article was included in Catalysis Communications in 2014.HPLC of Formula: 171032-87-4 This article mentions the following:

A triphenylphosphine-stabilized Ir/SiO₂ catalyst modified by a chiral diamine was synthesized with four silica spheres as support for the asym. hydrogenation of aromatic ketones. The H-bond between substrate and silanols and the interaction between substrate and modifier commonly affected the steric configuration of asym. hydrogenation of aromatic ketones. With the silanols increasing, the activity of asym. hydrogenation significantly increased. This is the first report of heterogeneous asym. hydrogenation of aromatic ketones enhanced by silanols on highly monodispersed silica spheres with > 99.9% ee and > 99% conversion. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4HPLC of Formula: 171032-87-4).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.HPLC of Formula: 171032-87-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Identification of chemicals leaching from dental resin-based materials after in vitro chemical and salivary degradation was written by Vervliet, Philippe;De Nys, Siemon;Duca, Radu Corneliu;Boonen, Imke;Godderis, Lode;Elskens, Marc;Van Landuyt, Kirsten L.;Covaci, Adrian. And the article was included in Dental Materials in 2022.Application In Synthesis of 2,2′-Oxybis(ethan-1-ol) This article mentions the following:

Only little is known about degradation of methacrylate monomers. Therefore, using in vitro chem. and saliva degradation this study aimed to identify the degradation products of organic compounds present in resin-based dental materials. Ten dental monomers and nine polymerized dental resin-based materials were immersed for 24 h in chem. media (0.1 M HCl, 0.1 M NaOH) and human pooled saliva in order to identify leached monomers and degradation products from chem. and saliva degradation Samples were analyzed using liquid chromatog. coupled to high-resolution mass spectrometry to identify previously unknown degradation products. During in vitro chem. degradation, uncured monomers were rapidly hydrolyzed into mono- and demethacrylated degradation products. During chem. degradation in alk. conditions of polymerized materials, considered the worst-case scenario, only degradation products could be detected. In acidic conditions, monomers and their degradation products were detected. In addition, different additives such as EDMAB, DMPA and HMBP were present in acidic degradation samples. Degradation in human pooled saliva for 24 h to mimic the in vivo situation, resulted in the identification of both monomers and their degradation products. Using state-of-the-art high-resolution mass spectrometry previously unknown degradation products of commonly used monomers were identified for the first time. Patients may be exposed to monomers and their degradation products in the first 24 h after restorative procedures. The results provide a base for further research on the degradation of resin-based dental composites in order to assess their safety using elution and toxicity studies. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of 2,2′-Oxybis(ethan-1-ol)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Metallacyclohexadiene and Metallabenzene Chemistry. Part 18. Synthesis, Structure, Spectroscopy, and Reactivity of a Neutral Iridathiabenzene was written by Bleeke, John R.;Hinkle, Paul V.;Shokeen, Monica;Rath, Nigam P.. And the article was included in Organometallics in 2004.Formula: C4H9NaS This article mentions the following:

Treatment of the cationic iridathiabenzene [cyclic][CH:C(Me)C(Me):CHS:Ir(PEt₃)₃]⁺BF₄^– (3) with Na tert-butylthiolate gives a stable neutral iridathiabenzene, [cyclic]CH:C(Me)C(Me):CHS:Ir(PEt₃)₂(S-tert-Bu) (4). Compound 4 exists in solution as an equilibrating mixture of two square pyramidal isomers, cis 4a and trans 4b. When 4 is cooled to -30° in MeCN, it precipitates as an MeCN adduct, [cyclic]CH:C(Me)C(Me):CHSIr(PEt₃)₂(S-tert-Bu)(NCMe) (6), featuring an iridathiacyclohexa-1,3-diene ring system. Compound 6 reverts back to 4 upon redissolving and warming to room temperature Treatment of 4 (or 6) with excess PMe₃ results in addition of PMe₃ to the Ir center and replacement of the bulky PEt₃ ligands with PMe₃‘s, producing [cyclic]CH:C(Me)C(Me):CHSIr(PMe₃)₃(S-tert-Bu) (7) as a mixture of equilibrating isomers, cis 7a and trans 7b. Compound 7, like 6, includes a nonaromatic iridathiacyclohexa-1,3-diene ring. When 4 in MeCN solvent (or 6) is reacted with trifluoromethanesulfonic acid, protonation occurs at the thiolate S, causing loss of thiol. The resulting cationic fragment dimerizes to produce [cyclic]{[CH:C(Me)C(Me):CHSIr(PEt₃)₂(NCMe)]₂}²⁺(O₃SCF₃^–)₂ (8), in which the two Ir centers are bridged by the two ring sulfurs. Finally, treatment of 4 (or 6) with [(η⁵-C₅Me₅)Ru(NCMe)₃]⁺O₃SCF₃^– gave the sandwich compound [cyclic]{η⁵-[CH:C(Me)C(Me):CHSIr(PEt₃)₂(S-tert-Bu)]Ru(η⁵-C₅Me₅)}⁺O₃SCF₃^– (9), which exists in solution as an equilibrating mixture of isomers, cis 9a and trans 9b. Compounds 4a, 7a, 8, and 9a were structurally characterized by x-ray diffraction. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Formula: C4H9NaS).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Formula: C4H9NaS

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Corrosion inhibition property and promotion of green basil leaves extract materials on Ti-Zr conversion composite coatings was written by Tian, Yuqin;Zhong, Li;Sheng, Xinxin;Zhang, Xinya. And the article was included in Advanced Composites and Hybrid Materials in 2022.Application In Synthesis of 5-Isopropyl-2-methylphenol This article mentions the following:

In this study, the extract obtained from green plant basil leaves was introduced into a corrosion medium NaCl solution to investigate the corrosion inhibition ability of basil leaves extract (BLE) on aluminum alloy (AA6061). The influence of BLE on the corrosion resistance of Ti-Zr conversion coatings (TiZrCCs) on AA6061 was also investigated. The protective performance of BLE on AA6061 was investigated through SEM (SEM). The TiZrCCs were characterized by SEM, XPS, and electrochem. tests including potentiodynamic polarization curves and electrochem. impedance spectroscopy. The results of SEM show that BLE effectively prevented AA6061 from producing corrosion products during immersion in corrosive media. As for the TiZrCCs, SEM results reveal that BLE helped to form a more complete conversion coating and greatly improved the problem of coating cracks. Compared with the blank conversion coating, the corrosion rate of the coating with the introduction of BLE decreased from 0.043 to 0.007 mpy. In addition, d. functional theory calculation was performed on several main substances in BLE, including methyleugenol, carvacrol, linalool, rosmarinic acid, and eugenol, and the reactivity and reaction sites of each mol. were theor. analyzed. The results indicate that rosmarinic acid has the maximum electronegativity and the min. hardness, as well as the best reactivity. Green plant basil leaves extract materials can effectively promote the coating formation process of titanium-zirconium conversion coatings and enhance the corrosion resistance of the coatings. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Application In Synthesis of 5-Isopropyl-2-methylphenol).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of 5-Isopropyl-2-methylphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synergistic catalysis within core-shell Fe₃O₄@SiO₂ functionalized with triethylene glycol (TEG)-imidazolium ionic liquid and tetramethylpiperidine N-oxyl (TEMPO) boosting selective aerobic oxidation of alcohols was written by Karimi, Babak;Ghaffari, Bahareh;Vali, Hojatollah. And the article was included in Journal of Colloid and Interface Science in 2021.Formula: C7H6Cl2O This article mentions the following:

It is expected that incorporation of 2, 2, 6, 6-tetra-Me piperidine-N-oxyl radical (TEMPO) and an imidazolium bromide bearing hydrophilic triethylene glycol (TEG) groups on Fe₃O₄@SiO₂ core-shell may not only result in a novel highly water-dispersible/magnetically separable multi-functional catalyst system for metal-free aerobic oxidation of alcs., which operates through a synergistic relay pathway, but it could potentially provide a strong platform for simultaneous separation and recycling of all components. The catalyst was prepared by anchoring TEMPO moieties onto a magnetic core-shell Fe₃O₄@SiO₂ functionalized with an ionic liquid bearing TEG groups. The materials was characterized using transmission electron microscopy, Fourier transform IR spectroscopy, nitrogen adsorption-desorption isotherms, thermal gravimetric anal., and elemental anal. The performance of the catalyst was evaluated and quant. measured in the aerobic oxidation of alcs. in water. The catalyst exhibited excellent and stable colloidal dispersion in water and high performance in the aerobic oxidation of various types of alcs. under metal- and halogen-free reaction conditions. As hypothesized, strong synergistic effect between functionalized components was seen in the described reaction. The catalyst displayed excellent dual-adjustable-selectivity in the oxidation of primary alcs. to either the corresponding aldehydes or carboxylic acids by tuning the reaction solvent and/or reaction time and excellent recycling behavior through a “double-separation-strategy”. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Formula: C7H6Cl2O).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Formula: C7H6Cl2O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The efficacy of the adjunct use of subgingival air-polishing therapy with erythritol powder compared to conventional debridement alone during initial non-surgical periodontal therapy was written by Divnic-Resnik, Tihana;Pradhan, Harold;Spahr, Axel. And the article was included in Journal of Clinical Periodontology in 2022.Application In Synthesis of (2R,3S)-rel-Butane-1,2,3,4-tetraol This article mentions the following:

Aim : To assess the efficacy of the adjunct use of a subgingival erythritol powder air-polishing device (EPAP) in comparison to conventional subgingival instrumentation alone during initial non-surgical periodontal therapy. Materials and Methods : Twenty-one patients with generalized Stages 2 and 3 grade B periodontitis were included in this single center, single blinded, split-mouth, randomized clin. trial. Teeth on the control side were treated with conventional hand and ultrasonic instrumentation, while those on the contralateral test side was treated using EPAP as adjunct to conventional subgingival instrumentation with hand and ultrasonic instruments. Three months after initial instrumentation, persisting pockets of ≥4 mm were re-treated, in both control and test sides, again with the resp. treatment approach-subgingival instrumentation alone on control, and subgingival instrumentation + EPAP on test side. Clin. parameters such as probing pocket depth (PPD), bleeding on probing, and relative attachment level were recorded at baseline and 3 and 6 mo following the initial instrumentation. Subgingival plaque samples were collected at baseline, immediately post surgery, as well as at 1 wk, 1 mo, 3 mo, and 6 mo after initial instrumentation. Results : In the test group after 6 mo, a significantly larger number of initially deep pockets (PPD ≥ 5.5 mm) were reduced to shallow (PPD ≤ 3.4 mm), and a larger attachment gain was observed No statistically significant microbiol. differences could be found between test and control group. Conclusions : The results of the present study indicate that the adjunct use of subgingival airflow therapy with EPAP during initial non-surgical periodontal therapy might be beneficial in initially deep pockets (PPD ≥ 5.5 mm). In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Application In Synthesis of (2R,3S)-rel-Butane-1,2,3,4-tetraol).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application In Synthesis of (2R,3S)-rel-Butane-1,2,3,4-tetraol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Agronomic and metabolomics analysis of rice-Tartary buckwheat (Fagopyrum tataricum Gaertn) bred by hybridization was written by Wang, Yan;Guan, Zhixiu;Liang, Chenggang;Liao, Kai;Xiang, Dabing;Huang, Juan;Wei, Chunyu;Shi, Taoxiong;Chen, Qingfu. And the article was included in Scientific Reports in 2022.Reference of 149-32-6 This article mentions the following:

Tartary buckwheat (TB) is an edible pseudocereal with good health benefits, but its adhering thick shell and bitter taste inhibit its consumption. In this study, the first hybrid rice-Tartary buckwheat (RTB) variety Mikuqiao18 (M18), bred by the pedigree selection of crossbreeding ‘Miqiao’ (MQ) with ‘Jingqiaomai2’ (JQ2), was selected for an agronomic and metabolomics anal. Compared with JQ2, M18 demonstrated a significantly lower yield per plant owing to the decreased grain weight and similar full-filling grain number per plant. However, M18 had a similar kernel weight per plant because of the thinner shell. The sense organ test suggested that M18 had higher taste quality regardless of partial replacement of rice through the improvement of preponderant indicators related to cereal taste quality, including lower values of total protein, albumin, glutelin, globulin, pasting temperature, cool paste viscosity, and setback. Meanwhile, M18 contained high levels of flavonoids, including rutin and quercetin, but presented a pos. summary appraisal of cooking with 25% rice. Addnl., 92 metabolites were pos. identified by GC-MS, including 59 differentially expressed metabolites (DEMs) between M18 and JQ2. Typically, M18 exhibited lower levels of 20 amino acids and higher levels of 6 sugars and 4 polyols. These DEMs might partly explain the superior eating quality of M18. In addition, M18 was abundant in 4-aminobutyric acid, which is beneficial to human health. The current findings offer a theor. foundation for breeding rice-Tartary buckwheat with high yield and quality and promoting the cultivation and consumption of rice-Tartary buckwheat as a daily functional cereal. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Reference of 149-32-6).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 149-32-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts