Month: February 2023

Hybrid collagen/pNIPAAM hydrogel nanocomposites for tissue engineering application was written by Tatiana, Nistor Manuela;Cornelia, Vasile;Tatia, Rodica;Aurica, Chiriac. And the article was included in Colloid and Polymer Science in 2018.Computed Properties of C10H14O5 This article mentions the following:

The present work explores new hybrid bioactive, enzymically degradable hydrogel nanocomposites. They are composed by stimuli-sensitive semi-interpenetrating collagen/poly(N-iso-Pr acrylamide) polymeric matrix, Dellite 67G and Cloisite 93A nanoclays, and hydroxyapatite particles. Morphol. of the hybrid hydrogel nanocomposites was examined by near IR chem. imaging, X-ray diffraction, SEM, and transmission electron microscopy techniques. It has been found that the porous hydrogel nanocomposites showed a mix between intercalated and exfoliated structure, with interconnected pores and the inorganic material was evenly distributed in the polymeric matrix because of specific interactions between components. The collagen resistance against enzymic degradation and the thermal stability were improved due to the protein encapsulation in the synthetic polymer matrix. The hydrogel nanocomposites showed suitable swelling characteristics for tissue engineering. In vitro cytocompatibility and cell viability revealed that the hybrid nanocomposites were non-cytotoxic for rat osteoblasts. These hybrid nanocomposites were designed as potential synthetic bone tissue engineering. [Figure not available: see fulltext.]. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Computed Properties of C10H14O5).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Computed Properties of C10H14O5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel Inorganic Mesoporous Material with Chiral Nematic Structure Derived from Nanocrystalline Cellulose for High-Resolution Gas Chromatographic Separations was written by Zhang, Jun-Hui;Xie, Sheng-Ming;Zhang, Mei;Zi, Min;He, Pin-Gang;Yuan, Li-Ming. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2014.Synthetic Route of C4H11NO This article mentions the following:

Chiral nematic mesoporous silica (CNMS) has attracted widespread attention due to some unique features, such as its nematic structure, chirality, large pore size, high temperature resistance, low cost, and ease of preparation The authors 1st reported the use of CNMS as a stationary phase for capillary gas chromatog. (GC). The CNMS-coated capillary column not only gives good selectivity for the separation of linear alkanes, aromatic hydrocarbons, polycyclic aromatic hydrocarbons (PAHs), and isomers but also offers excellent enantioselectivity for chiral compounds Compared with enantioseparations on com. β-DEX 120 and Chirasil-L-Val columns, a CNMS-coated capillary column offers excellent enantioselectivity, chiral recognition complementarity, and the separation of analytes within short elution times. It can also be potentially applied in high-temperature GC at >350°. CNMS could soon become very attractive for separations In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Synthetic Route of C4H11NO).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C4H11NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Visible Light-Induced Hydrosilylation of Electron-Deficient Alkenes by Iron Catalysis was written by Ding, Ling;Niu, Kaikai;Liu, Yuxiu;Wang, Qingmin. And the article was included in ChemSusChem in 2022.SDS of cas: 2216-51-5 This article mentions the following:

Regioselective photochem. hydrosilylation of activated alkenes R¹CH:CR²(EWG) with Ph₃SiH catalyzed by iron trichloride, afforded linear triphenylsilanes Ph₃SiCHR¹CHR²(EWG) (R¹, R² = H, Me, CF₃, CO₂Me; EWG = carboxylate, CN, CHO, CONHPh). Herein, we reported a method for iron-catalyzed, visible-light-induced hydrosilylation reactions of electron-deficient alkenes to produce value-added silicon compounds Alkenes bearing functional groups with different steric properties were suitable substrates, as were derivatives of structurally complex natural products. Mechanistic studies showed that chlorine radicals generated by iron-catalyzed ligand-to-metal charge transfer in the presence of lithium chloride promoted the formation of silyl radicals. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Catalytic Asymmetric β-Oxygen Elimination was written by Matt, Christof;Orthaber, Andreas;Streuff, Jan. And the article was included in Angewandte Chemie, International Edition in 2022.SDS of cas: 2216-51-5 This article mentions the following:

A catalytic enantioselective β-O-elimination reaction is reported in the form of a zirconium-catalyzed asym. opening of meso-ketene acetals. Furthermore, a regiodivergent β-O-elimination is demonstrated. The reaction proceeds under mild conditions, at low catalyst loadings, and produces chiral monoprotected cis-1,2-diols in good yield and enantiomeric excess. The combination with a Mitsunobu reaction or a one-pot hydroboration/Suzuki reaction sequence then gives access to addnl. diol and aminoalc. building blocks. A stereochem. anal. supported by DFT calculations reveals that a high selectivity in the hydrozirconation step is also important for achieving high enantioselectivity, although it does not constitute the asym. step. This insight is crucial for the future development of related asym. β-elimination reactions. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Single particle measurements of mixing between mimics for biomass burning and aged secondary organic aerosols was written by Habib, Luke;Donahue, Neil. And the article was included in Environmental Science: Atmospheres in 2022.Recommanded Product: 149-32-6 This article mentions the following:

Gas-phase exchange between aerosol populations via evaporation and condensation of semi-volatile organics can be a major mechanism of mixing between accumulation-mode particles with slow coagulation. This exchange may be impeded in highly viscous, semi-solid, or glassy particles due to diffusion limitations. Here we describe experiments on carefully prepared particle populations representing highly viscous or potentially “glassy” aged organic particles (non-volatile sugars 13C-glucose, sucrose, and raffinose with ammonium sulfate seeds) and fresh biomass burning particles (erythritol with black carbon seeds) to develop a model phase space for organic aerosol systems and better understand when particle phase state impedes mixing. Our hypothesis is that these limitations are alleviated at some relative humidity threshold, which increases with decreasing ambient temperatures We quantify the mixing state of these particle populations from 10-25°C and 5-90% RH using an Aerosol Mass Spectrometer (AMS) combining Event Trigger (ET) and Soot Particle (SP) modes. The observed single particle mass spectra are aggregated in short time slices and used to perform a linear combination of relevant reference spectra to determine the contributions each constituent has on the resulting particle signal. Our results suggest that the non-volatile sugar particles have little to no diffusive limitations to mixing at the conditions tested. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Recommanded Product: 149-32-6).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 149-32-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Co-Assembly of Chiral Amines and a Four-Armed Cyano-Substituted Luminophore through Hydrogen Bonds for Potential Development of Smart Chiroptical Materials was written by Liu, Yiping;Hao, Aiyou;Xing, Pengyao. And the article was included in Chemistry – A European Journal in 2022.Category: alcohols-buliding-blocks This article mentions the following:

Chirality transfer from chiral mols. to assemblies is of vital importance to the design of functional chiral materials. In this work, selective co-assembly behaviors between chiral mols. and an achiral luminophore, potentially driven by the intermol. salt-bridge type hydrogen bonds are reported. Cyano-substituted tetrakis(arylthio)benzene carboxylic acid (TA) served as the luminophore and hydrogen bond donors, which underwent co-assembly with different chiral amines. It was found that structures of chiral amines affect the chirality transfer and the properties of co-assemblies due to effects on hydrogen bonds and stacking pattern. Only in specific co-assemblies, the chiroptical properties occurred at both ground state and excited states based on the emerged Cotton effects and circularly polarized luminescence (CPL) signals, revealing that the chirality was successfully transferred from mol. level to supramol. level. In addition, accurate quant. examination of chiral amines was realized by CD spectra. This work demonstrates the characteristic chirality response and transfer through co-assembly, providing a potential method to develop smart chiroptical materials. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Category: alcohols-buliding-blocks).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Erythritol confined in multiwalled carbon nanotubes reinforced silica aerogel as novel form-stable phase change materials was written by Li, Qi;Feng, Yang;Li, Yi-Ting;Ning, Yu-Hao;Hu, Ping;Lin, Chuan-Huang;Zhang, Yi-Hong;Zhou, Mei;Yu, Lin-Ping;Li, Chuan-Chang;Cao, Zhong;Zeng, Ju-Lan. And the article was included in Journal of Molecular Liquids in 2022.SDS of cas: 149-32-6 This article mentions the following:

In this work, pristine multiwalled carbon nanotubes (MCNTs) and mixed acids treated MCNTs (ACNTs) were applied as reinforcement fillers to prepare silica aerogels via ambient pressure drying followed by lyophilization. The prepared aerogels were then used as supporting materials to adsorb meso-erythritol (ME) to obtain novel form-stable PCMs by vacuum infiltration. Investigation of the prepared form-stable PCMs revealed that the ACNT/SiO₂ aerogels possessed higher porosity than MCNT/SiO₂ aerogels due to that the ACNTs exhibited stronger interactions with silica than the MCNTs, and could more effectively prevent the prepared ACNT/SiO₂ aerogels from collapsing and shrinking during drying. Consequently, the loading of ME in the form-stable PCMs supported by ACNT/SiO₂ aerogels (AFPCMs) was greatly higher than that in the form-stable PCMs supported by MCNT/SiO₂ aerogels (MFPCMs). When ACNT/SiO₂-6 aerogel, in which 60 mg ACNTs were used as reinforcement filler, was applied as supporting material, the obtained form-stable PCM (AFPCM-6) exhibited a very high melting latent heat of 297.3 J/g, an elevated crystallizing temperature of 56°C and an improved crystallizing latent heat of 231 J/g. Besides, the latent heat storage/release properties of AFPCM-6 maintained stable enough over 50 melting/crystallizing cycles. Meanwhile, the thermal conductivity of AFPCM-6 was 37.5% higher than that of pure ME. Hence, AFPCM-6 could be an excellent form-stable PCM and could find its applications in related fields. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6SDS of cas: 149-32-6).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.SDS of cas: 149-32-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tf₂O- and Cu(OTf)₂-Assisted Acylamination Reaction of Unactivated Alcohols with Nitriles: A One-Pot P(IV) Activation, Stereoretention in Cycloalkanols and Deprotection Approach was written by Bhat, Mohammad Yaqoob;Ahmed, Sajjad;Ahmed, Qazi Naveed. And the article was included in Journal of Organic Chemistry in 2022.SDS of cas: 2216-51-5 This article mentions the following:

Described herein is a simple, novel, one-pot acylamination reaction of unactivated alcs. This reaction employs the combination of PCl₃ and triflic anhydride (Tf₂O) or copper triflate Cu(OTf)₂, which serves as a source of P(IV)-activated complex for nitriles to react under the Ritter-type mechanism. The synthetic utility of Tf₂O-promoted reactions was demonstrated by its effectiveness to generate different acylaminated products. By employing Cu(OTf)₂, this method represented a rare example of α-selective acylamination reaction. With chiral cycloalkanols, using the Cu(OTf)₂-promoted procedure, acylaminated products were formed with complete retention of configuration. The synthetic utility of the copper-assisted reaction in acetonitrile was readily demonstrated as a mild deprotection strategy. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5SDS of cas: 2216-51-5).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.SDS of cas: 2216-51-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Direct Conversion of Primary Alcohols to 1,2-Amino Alcohols: Enantioselective Iridium-Catalyzed Carbonyl Reductive Coupling of Phthalimido-Allene via Hydrogen Auto-Transfer was written by Spielmann, Kim;Xiang, Ming;Schwartz, Leyah A.;Krische, Michael J.. And the article was included in Journal of the American Chemical Society in 2019.HPLC of Formula: 142253-56-3 This article mentions the following:

The first catalytic enantioselective carbonyl (α-amino)allylations are described. Phthalimido-allene and primary alcs. engage in hydrogen auto-transfer-mediated carbonyl reductive coupling by way of (α-amino)allyliridium-aldehyde pairs to form vicinal amino alcs. with high levels of regio-, anti-diastereo-, and enantioselectivity. Reaction progress kinetic anal. and isotopic labeling studies corroborate a catalytic cycle involving turnover-limiting alc. dehydrogenation followed by rapid allene hydrometalation. In the experiment, the researchers used many compounds, for example, 1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3HPLC of Formula: 142253-56-3).

1-Boc-Azetidine-3-yl-methanol (cas: 142253-56-3) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 142253-56-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Formulation of infant formula with different casein fractions and their effects on physical properties and digestion characteristics was written by Zhang, Junpeng;Du, Xinyu;Jiang, Shilong;Xie, Qinggang;Mu, Guangqing;Wu, Xiaomeng. And the article was included in Food & Function in 2022.SDS of cas: 137-08-6 This article mentions the following:

This study investigated whether casein (CN) fractions exhibit better phys. properties and digestibility than native casein micelles presently used in the production of infant formula. The structural performance of native casein micelles (micellar casein concentrates, MCC), β-CN, κ-CN and β + κ-CN were explored, and phys. properties and digestion characteristics (i.e., digestibility, particle size, zeta potential and microscopic morphol.) of the infant formula with MCC, β-CN, κ-CN or β + κ-CN were determined to elucidate the applicability of these casein types in infant formula. Results indicated that the β + κ-CN infant formula solution had the largest particle size with the most unstable potential. Moreover, both β-CN and κ-CN infant formula showed high solubility, while κ-CN displayed the lowest foaming capacity and high foaming stability. β-CN infant formula expressed an effective digestibility property, however, it possessed the largest particle size after gastrointestinal digestion. Therefore, β-CN fraction infant formula showed better digestibility than casein infant formula, and thus this work provides a theor. basis for the development of infant formula. In the experiment, the researchers used many compounds, for example, Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6SDS of cas: 137-08-6).

Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate (cas: 137-08-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.SDS of cas: 137-08-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts