Month: January 2023

A multivalent mixed-metal strategy for single-Cu⁺-ion-bridged cluster-based chalcogenide open frameworks for sensitive nonenzymatic detection of glucose was written by Zhang, Jiaxu;Wang, Xiang;Lv, Jing;Li, Dong-Sheng;Wu, Tao. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.HPLC of Formula: 5856-63-3 This article mentions the following:

Here we report two new metal-chalcogenide open frameworks (MCOFs) with large-sized supertetrahedral clusters bridged by an accessible single-cuprous ion via a multivalent mixed-metal strategy. Such Cu-rich semiconductor MCOFs have been investigated for the first time for nonenzymic detection of glucose, and display good sensitivity and stability. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3HPLC of Formula: 5856-63-3).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 5856-63-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Analytical applications of ion-exchange materials. V. Chromatographic separation of drugs on ferric phosphate papers was written by Thind, P. S.;Gandhi, J. S.. And the article was included in Journal of Liquid Chromatography in 1983.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

Chromatog. of 14 drugs is performed on papers impregnated with ferric phosphate. Nine solvent systems (phosphate buffers with different pHs, EtOH and EtOH-benzene) are used based on aqueous phosphate buffers and mixed organic solvents. The R_f values on plain and impregnated papers are compared. Binary separations are described. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Quality Control of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Comparative study on nucleophilic/electrophilic behaviour of divalent organosulfur compounds: a DFT study was written by Ahmed, Nizamuddin;Bhattacharjee, Saibal Kanti;Bhattacharyya, Pradip Kr.. And the article was included in Journal of the Indian Chemical Society in 2014.Related Products of 29364-29-2 This article mentions the following:

Electrophilic/nucleophilic behavior of twenty-five bivalent organosulfur compounds were studied using global and local DFT based reactivity descriptors at B3LYP/6-311++G(d,p) and MP2/6-311++G(d,p) levels of theory. Global reactivity descriptors are used to observe overall stability of the compounds and local parameters are used to quantify reactivity of the sulfur center. Further we have observed the effect of solvents, ethanol and water on the reactivity pattern. Gibbs free energy of solvation is used to measure stability of the compounds in solvent phases. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Related Products of 29364-29-2).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Related Products of 29364-29-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Magnetic spent coffee ground as an efficient and green catalyst for aerobic oxidation of alcohols and tandem oxidative Groebke-Blackburn-Bienayme reaction was written by Farhid, Hassan;Shaabani, Ahmad. And the article was included in Journal of the Iranian Chemical Society in 2021.Recommanded Product: 1777-82-8 This article mentions the following:

Abstract: In this work, magnetic spent coffee ground as a green, inexpensive, and abundant material was synthesized and characterized by a variety of techniques, including X-ray diffraction pattern, thermal gravimetric anal., SEM, energy-dispersive spectroscopy, inductively coupled plasma optical emission spectrometry, and Fourier transform IR spectroscopy. The magnetic spent coffee ground was successfully utilized as a catalyst in aerobic oxidation of primary and secondary benzylic alcs. and tandem oxidative Groebke-Blackburn-Bienayme ́reaction. Graphic abstract: [graphic not available: see fulltext]. In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Recommanded Product: 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Host-guest complexation. 3. Organization of pyridyl binding sites was written by Newcomb, Martin;Timko, Joseph M.;Walba, David M.;Cram, Donald J.. And the article was included in Journal of the American Chemical Society in 1977.Recommanded Product: 6-Methyl-2-pyridinemethanol This article mentions the following:

Six new multiheteromacrocycles were prepared containing as part of the major ring system from one to four 2,6-pyridinedimethylyl units. The pKa of these compounds were comparable to those of open-chain models except for that of sym-dipyridyl-12-crown-4, e.g., I, whose conjugate acid was 4 kcal/mol more stable than the others. The 18-membered cycles, e.g., II, gave free energies of association for complexation with tert-BuNH3SCN in CDCl3 about 5 kcal/mol more neg. (complexes more stable) than either the 12- or the 24-membered ring systems. In CDCl3 for five 18-membered host compounds containing widely different binding units, tert-BuNH3SCN was better complexed than tert-BuNH3Cl by 2.9 ± 0.1 kcal/mol at 0°. Of the 13 possible 18-membered ring pyridocycles containing 6 binding sites that are either O or N, 3 were synthesized. The free energies of complexation of these cycles and 18-crown-6 with tert-BuNH3Cl were determined at 0° and estimated at 24°. The values for 3 of these cycles were dissected into 6 host-guest contact site parameters (4 different kinds) whose addition equaled the free energies of association of host and guest. The parameters taken in appropriate combinations dictated by host structure were then used to calculate the free energies of association of the 4th cycle. The measured and calculated values were in reasonable agreement. The 4 different kinds of free-energy contact site parameters were then used to predict the free energies of association of the remaining unsynthesized 10 cycles. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Recommanded Product: 6-Methyl-2-pyridinemethanol).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 6-Methyl-2-pyridinemethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cyclic (Alkyl)(amino)carbene Ligands Enable Cu-Catalyzed Markovnikov Protoboration and Protosilylation of Terminal Alkynes: A Versatile Portal to Functionalized Alkenes was written by Gao, Yang;Yazdani, Sima;Kendrick, Aaron IV;Junor, Glen P.;Kang, Taeho;Grotjahn, Douglas B.;Bertrand, Guy;Jazzar, Rodolphe;Engle, Keary M.. And the article was included in Angewandte Chemie, International Edition in 2021.Computed Properties of C16H20B2N2O2 This article mentions the following:

Regioselective hydrofunctionalization of alkynes represents a straightforward route to access alkenyl boronate and silane building blocks. In previously reported catalytic systems, high selectivity is achieved with a limited scope of substrates and/or reagents, with general solutions lacking. Herein, we describe a selective copper-catalyzed Markovnikov hydrofunctionalization of terminal alkynes that is facilitated by strongly donating cyclic (alkyl)(amino)carbene (CAAC) ligands. Using this method, both alkyl- and aryl-substituted alkynes are coupled with a variety of boryl and silyl reagents with high α-selectivity. The reaction is scalable, and the products are versatile intermediates that can participate in various downstream transformations. Preliminary mechanistic experiments shed light on the role of CAAC ligands in this process. In the experiment, the researchers used many compounds, for example, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6Computed Properties of C16H20B2N2O2).

2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine (cas: 1214264-88-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Computed Properties of C16H20B2N2O2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electrospinning of photocrosslinked and degradable fibrous scaffolds was written by Tan, Andrea R.;Ifkovits, Jamie L.;Baker, Brendon M.;Brey, Darren M.;Mauck, Robert L.;Burdick, Jason A.. And the article was included in Journal of Biomedical Materials Research, Part A in 2008.Formula: C10H14O5 This article mentions the following:

Electrospun fibrous scaffolds are being developed for the engineering of numerous tissues. Advantages of electrospun scaffolds include the similarity in fiber diameter to elements of the native extracellular matrix and the ability to align fibers within the scaffold to control and direct cellular interactions and matrix deposition. To further expand the range of properties available in fibrous scaffolds, we developed a process to electrospin photocrosslinkable macromers from a library of multifunctional poly(β-amino ester)s. In this study, we utilized one macromer (A6) from this library for initial examination of fibrous scaffold formation. A carrier polymer [poly(ethylene oxide) (PEO)] was used for fiber formation because of limitations in electrospinning A6 alone. Various ratios of A6 and PEO were successfully electrospun and influenced the scaffold fiber diameter and appearance. When electrospun with a photoinitiator and exposed to light, the macromers crosslinked rapidly to high double bond conversions and fibrous scaffolds displayed higher elastic moduli compared to uncrosslinked scaffolds. When these fibers were deposited onto a rotating mandrel and crosslinked, organized fibrous scaffolds were obtained, which possessed higher moduli (∼4-fold) in the fiber direction than perpendicular to the fiber direction, as well as higher moduli (∼12-fold) than that of nonaligned crosslinked scaffolds. With exposure to water, a significant mass loss and a decrease in mech. properties were observed, correlating to a rapid initial loss of PEO which reached an equilibrium after 7 days. Overall, these results present a process that allows for formation of fibrous scaffolds from a wide variety of possible photocrosslinkable macromers, increasing the diversity and range of properties achievable in fibrous scaffolds for tissue regeneration. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8Formula: C10H14O5).

Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Formula: C10H14O5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Asymmetric reduction of acetophenone analogues by Alternaria alternata using ram horn peptone was written by Kurbanoglu, Esabi B.;Zilbeyaz, Kani;Kurbanoglu, Namudar I.;Kilic, Hamdullah. And the article was included in Tetrahedron: Asymmetry in 2007.Safety of (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:

Alternaria alternata EBK-4 fungus isolated from a plant sample was evaluated for the asym. reduction of acetophenone analogs. In a previous study, this isolate was used for the reduction of acetophenone to 1-phenylethanol in excellent enantiomeric excess. The substituted acetophenones were converted to the corresponding optically active alc. by A. alternata EBK-4 under optimized conditions in up to >99% enantiomeric excess (ee). This is the first report on the enantiomeric reduction of acetophenone analogs by A. alternata using ram horn peptone from waste material. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Safety of (S)-1-(2-Fluorophenyl)ethanol).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of (S)-1-(2-Fluorophenyl)ethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mechanistic and synthetic aspects of hydroboration with a simple atropisomeric ligand prepared from 1-(1′-isoquinolyl)-2-naphthol was written by Korostylev, Andrei;Gridnev, Ilya;Brown, John M.. And the article was included in Journal of Organometallic Chemistry in 2003.Reference of 171032-87-4 This article mentions the following:

A novel triaryl phosphite ligand was prepared directly from both enantiomers of BINOL and a single enantiomer of 1-(1′-isoquinolyl)-2-naphthol. In one of the two cases the cationic Rh complex proved to be reasonably effective in the asym. hydroboration of electron-poor styrenes. It was possible to identify binuclear reactive intermediates when the hydroboration pre-catalyst was examined in the presence of catecholborane at low temperatures In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Reference of 171032-87-4).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Reference of 171032-87-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluation of cosmetic creams containing Black cumin (Nigella sativa)-Lemon balm (Melissa officinalis L.)-Aloe vera (Aloe barbadensis miller) essences by modeling with Box Behnken method in Design Expert was written by Turedi, Ece;Acarali, Nil. And the article was included in Industrial Crops and Products in 2022.Reference of 499-75-2 This article mentions the following:

In this investigation regarding medicinal and aromatic plants, an exptl. study was conducted on the effectiveness of black cumin, lemon balm and Aloe vera essences in cosmetic creams, which were selected for their beneficial biol. activities such as anti-inflammatory, moisturizing, etc. In line with this study stability test, which was important in the quality evaluation of cosmetic products, was carried out. Cream samples containing different concentrations of black cumin and lemon balm essences were kept at under 3 different temperature conditions as 0 °C, 25 °C and 40 °C and the necessary values were recorded. In this direction, the effects of the temperature on the phys. and chem. properties of the cosmetic creams were assessed. Homogenization and colors as phys. properties and pH value of the herbal cream samples were examined It was observed that the pH value, which was an important parameter for skin care products, was 6.5 under the optimum exptl. condition and it was an acceptable value for skin creams according to the literature. In the second part of the exptl. study, the effect of the essence obtained from the Aloe vera plant on the samples was tested with the optimum condition selected from 17 different exptl. sets by using the Design Expert optimization application. In addition, from the production of cosmetic products; it was necessary to pay attention to the environmental conditions stipulated in storage, transportation, and sales points. As a result of the tests, it was seen that the medicinal and aromatic plants used could be evaluated in the field of cosmetics and successful results could be obtained. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Reference of 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Reference of 499-75-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts