Month: January 2023

The aggregation pheromone of the German cockroach, Blattella germanica (L.)(Dictyoptera: Blattellidae): isolation and identification of the attractant components of the pheromone was written by Sakuma, Masayuki;Fukami, Hiroshi. And the article was included in Applied Entomology and Zoology in 1990.Related Products of 14123-48-9 This article mentions the following:

Attractant components of the aggregation pheromone of the German cockroach, B. germanica, were isolated from frass-contaminated filter paper. Successive purification steps were monitored by olfactometer assay, and each attractant component was eventually identified by gas chromatog. (GC)-mass spectrometry and the assay on each preparative GC fraction. The attractant comprised several volatile amines. Amine evaporation was restricted by salt formation with acid(s) in the excreta. All the identified NH₃ and 12 amines exerted both chemotaxis and anemotaxis on B. germanica nymphs. Typical excretory materials such as NH₃, methylamine, dimethylamine, and trimethylamine were the major components. The most active component was 1-dimethylamino-2-methyl-2-propanol (ED₅₀ = 10 pmol/L air), which was 50-1000-fold more active than the others. In the experiment, the researchers used many compounds, for example, 1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9Related Products of 14123-48-9).

1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 14123-48-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis and biological activity profile of novel triazole/quinoline hybrids was written by Jamshidi, Hoda;Naimi-Jamal, Mohammad Reza;Safavi, Maliheh;RayatSanati, Kimia;Azerang, Parisa;Tahghighi, Azar. And the article was included in Chemical Biology & Drug Design.HPLC of Formula: 1777-82-8 This article mentions the following:

A novel series of 1,2,3-triazole-based polyaromatic compounds containing chloroquinoline moiety I (Ar = 4-ClC₆H₄, 4-O₂NC₆H₄, 4-MeOC₆H₄, etc.) was synthesized through a well-established synthetic methodol., named click chem. The structure of the synthetic compounds was characterized by various spectroscopic methods. The final products of triazole/quinoline hybrids I and ((prop-2-yn-1-yloxy)methyl)benzene intermediates HCCCH₂OCH₂Ar were screened for their antibacterial (Staphylococcus aureus, Escherichia coli, Shigella flexneri, and Salmonella enterica), antifungal (Candida albicans, Saccharomyces cerevisiae, and Aspergillus fumigatus), and cytotoxic activities. The best antifungal compounds exhibited min. inhibitory concentration (MIC), in the range of 0.35-0.63 μM, against S. cerevisiae without any cytotoxic effect. These compounds can be selected as the potential candidates for treating invasive fungal infections caused by S. cerevisiae, after further investigation. Preliminary in silico ADME studies also predicted the favorable pharmacokinetic attributes of most compounds In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8HPLC of Formula: 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.HPLC of Formula: 1777-82-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sulfur-Rich Zinc Chemistry: New Tris(thioimidazolyl)hydroborate Ligands and Their Zinc Complex Chemistry Related to the Structure and Function of Alcohol Dehydrogenase was written by Tesmer, Markus;Shu, Mouhai;Vahrenkamp, Heinrich. And the article was included in Inorganic Chemistry in 2001.Formula: C7H9NO This article mentions the following:

The 1-substituted tris(2-thioimidazolyl)hydroborate ligands Tt^R were prepared as the K salts from KBH₄ and the corresponding 1-R-2-thioxoimidazole for R = t-Bu and C₆H₄-p-CHMe₂ (Cum). Their reactions with Zn salts yielded the tetrahedral complexes Tt^RZn-X with X = F, Cl, ONO₂ and (Tt^t-Bu)₂Zn. With Zn(ClO₄)₂ the labile perchlorate complexes Tt^RZn-OClO₃ were obtained. They served as starting materials for the incorporation of substrates which are relevant for the chem. of horse liver alc. dehydrogenase: EtOH led to [Tt^t-BuZn·EtOH] ClO₄·EtOH, p-nitrophenol (NitOH) yielded Tt^CumZn-ONit. Pyridine-2-carbaldehyde and salicylaldehyde were incorporated as N(pyridine) and O(phenolate) coligands with possible addnl. O(aldehyde) coordination. Substituted pyridylmethanols (R-PyCH₂OH) yielded trinuclear [(Tt^t-Bu)₂Zn₃(R-PyCH₂O)₂](ClO₄)₂ with bridging Tt and pyridylmethoxide ligands. Preliminary experiments on the functional modeling of alc. dehydrogenase showed that TtZn complexes promote both the dehydrogenation of iso-PrOH and the hydrogenation of pentafluorobenzaldehyde. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Formula: C7H9NO).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Formula: C7H9NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis and Characterization of Novel Volatile Imido-Aminoalkoxide Tantalum Compounds was written by Park, Bo Keun;Kim, Hyo-Suk;Shin, Su Jung;Min, Jae Ki;Lee, Kang Mun;Do, Youngkyu;Kim, Chang Gyoun;Chung, Taek-Mo. And the article was included in Organometallics in 2012.Application In Synthesis of 1-(Dimethylamino)-2-methylpropan-2-ol This article mentions the following:

A novel Ta(V) ^tBu-imido/aminoalkoxide complex, Ta(N^tBu)(dmamp)₂Cl (1), was synthesized by metathesis reaction between Ta(N^tBu)Cl₃(py)₂ and 2 equiv of Na(dmamp), and subsequent reaction of 1 with 1 equiv of MeLi gave a new tantalum complex, Ta(N^tBu)(dmamp)₂Me (2). Compounds 1 and 2 have been characterized by IR, ¹H and ¹³C NMR spectroscopy, and microanal. data. The mol. structure of 1, determined by x-ray single crystallog., revealed distorted octahedral geometry. The behavior of compound 1 in solution was studied by variable-temperature ¹H NMR spectra. Thermogravimetric anal. revealed superior thermal properties of 2 as compared to those of 1. In the experiment, the researchers used many compounds, for example, 1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9Application In Synthesis of 1-(Dimethylamino)-2-methylpropan-2-ol).

1-(Dimethylamino)-2-methylpropan-2-ol (cas: 14123-48-9) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of 1-(Dimethylamino)-2-methylpropan-2-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Phytochemical investigation of Cissus aralioides stems from Cote d′Ivoire was written by Kouassi, Affoue Delphine;Baguia-Broune, Fatou Diane Michelle;Ngaman-Kouassi, Kohue Christelle Chantal;Mamyrbekova-Bekro, Janat Akhanovna;Virieux, David;Bekro, Yves-Alain. And the article was included in American Journal of PharmTech Research in 2021.Safety of (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol This article mentions the following:

As part of research on plants of interest for the floristic biodiversity of Cote d′Ivoire, a phytochem. investigation of the stems of Cissus aralioides, a species with medicinal properties of the botanical family Vitaceae, was produced. The mineral and organic compositions of said extract were determined, resp. by X-ray fluorescence spectrometry and by GC-MS. Elemental chem. anal. revealed considerable levels of trace elements (Fe, Mn, Zn), macro elements (Ca, Mg, P, K), and the presence of other elements (Ba, Ti, La, Cs, Rb, Ta, Cd). Anal. by GC-MS shows the existence of several active ingredients such as phenol acids, flavonoids, stilbenes and phytosterols. A major phytosterol (E-resveratrol) has been isolated from C. aralioides growing in Ivory Coast. In the experiment, the researchers used many compounds, for example, (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6Safety of (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol).

(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol (cas: 10083-24-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Safety of (E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Characterization of indigenous coagulase-negative staphylococci isolated from Chinese spontaneously fermented meat products was written by Chen, Juan;Zhang, Jingbin;Yang, Ziyao;Niu, Ying;Cai, Zijian;Wang, Jie;Yin, Liguo;Lin, Yaqiu;Lu, Xiaonan. And the article was included in Microbiological Research in 2022.COA of Formula: C8H16O This article mentions the following:

Technol., safety-related and volatile properties were analyzed in coagulase-neg. staphylococci (CNS) isolates from Chinese spontaneously fermented meat products. A total of 107 CNS isolates were identified via 16 S rRNA sequencing, and the most recovered species were S. saprophyticus (53.3%), S. edaphicus (12.1%), and S. epidermidis (10.3%). Among them, 58 CNS isolates belonging to 9 species were selected with higher activities of catalase, nitrate reductase, proteolysis, and lipolysis, as well as higher tolerance to stressful environmental conditions. Then, 7 CNS isolates belonging to 4 species were further selected based upon excellent technol. characteristics, lack of hemolysis and antibiotic resistance, and a low production of biogenic amines. The volatile profiles of these 7 strains cultivated in pork broth was determined S. casei Number 1 produced significant amounts of phenethyl alc., geraniol, and 3-methyl-butanol. S. xylosus Number 120 produced the highest amount of Me ketones with the potential to provide dry-cured odor of fermented meats. The volatile profile was highly strain dependent. Several CNS identified in this study have the potential to be used as the starter cultures for fermented meat products. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4COA of Formula: C8H16O).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.COA of Formula: C8H16O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Arylazo Sulfones as Nonionic Visible-Light Photoacid Generators was written by Di Terlizzi, Lorenzo;Martinelli, Angelo;Merli, Daniele;Protti, Stefano;Fagnoni, Maurizio. And the article was included in Journal of Organic Chemistry.Synthetic Route of C10H20O This article mentions the following:

The selective visible-light-driven generation of a weak acid (sulfinic acid, in nitrogen-purged solutions) or a strong acid (sulfonic acid, in oxygen-purged solutions) by using shelf-stable arylazo sulfones was developed. These sulfones were then used for the green, smooth, and efficient photochem. catalytic protection of several (substituted) alcs. (and phenols) as tetrahydropyranyl ethers or acetals. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Synthetic Route of C10H20O).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Synthetic Route of C10H20O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Comparative evaluation of encapsulation using β-cyclodextrin versus freeze-drying for better retention and stabilizing of black Perigord truffle (Tuber melanosporum) aroma was written by Phong, Win Nee;Al-Salami, Hani;Gibberd, Mark R.;Dykes, Gary A.;Payne, Alan D.;Coorey, Ranil. And the article was included in Journal of Food Science in 2022.Quality Control of Oct-1-en-3-ol This article mentions the following:

This study aimed to develop a novel technique to retain and stabilize compounds contributing to truffle aroma by encapsulation using β-cyclodextrin. Two experiments were conducted. In the first experiment, the key volatile profile and microbial population of products resulting from three different encapsulation methods, namely direct mixing method (M1), direct mixing followed by ethanol addition method (M2), and paste method (M3), were compared with untreated truffles (pos. control) over a 90-day period. The M2-derived product was the least optimal for retaining key volatile compounds despite showing the lowest microbial population. There was no significant difference in the volatile profile of products derived from M1 and M3 on day 0. However, it was observed that the M3-derived product could retain its volatile profile better than the M1-derived product by day 90. M3 was compared with freeze-drying in the second experiment Freeze-dried truffles showed an overall higher relative percentage of volatiles than the M3-derived product on day 0. However, by day 90, some volatile changes occurred in the freeze-dried truffles but not in the M3-derived product. The findings indicate that while freeze-drying could adequately conserve truffle volatiles, the encapsulation of volatile compounds in β-cyclodextrin could improve the volatile stability of truffle products and allow for longer storage times. Microbes were found in all encapsulated truffle products and freeze-dried truffles on days 0 and 90, suggesting the need to explore the possibility of incorporating a decontamination step in the process prior to either encapsulation or freeze-drying. Practical Application : A technique to capture and stabilize compounds responsible for truffle aroma by encapsulation using β-cyclodextrin was developed and compared with freeze-drying in this study. The overall finding suggests that while freeze-drying of truffle could sufficiently preserve volatiles, encapsulating truffle volatiles with β-cyclodextrin may improve its stability, extending its shelf life, which can be applied in the development of a natural truffle ingredient that can be applied in food product development. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4Quality Control of Oct-1-en-3-ol).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of Oct-1-en-3-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Stereoselective synthesis of N,N’-diacyl-p-menthan-1,8-diamines was written by Koval’skaya, S. S.;Kozlov, N. G.;Tikhonova, T. S.. And the article was included in Khimiya Prirodnykh Soedinenii in 1989.SDS of cas: 2451-01-6 This article mentions the following:

Reaction of terpin hydrate with RCN (R = Me, ClCH₂, Me₂CH, Ph) under Ritter reaction conditions stereoselectively leads to the formation of isomeric cis– and trans–N,N‘-diacyl-p-menthane-1,8-diamines in a 1:4 ratio. Structures were confirmed by proton and ¹³C NMR spectroscopy. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6SDS of cas: 2451-01-6).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 2451-01-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Regioselective ring-opening of epoxides with amines using Zn(ClO₄)₂-Al₂O₃ as a heterogeneous and recyclable catalyst was written by Maheswara, Muchchintala;Rao, Kummari Subba Venkata Krishna;Do, Jung Yun. And the article was included in Tetrahedron Letters in 2008.Product Details of 40571-86-6 This article mentions the following:

A simple and efficient method has been developed for the synthesis of β-amino alcs. by regioselective ring-opening of epoxides with amines in the presence of zinc perchlorate-neutral alumina as a heterogeneous recyclable catalyst at room temperature in high yields. In the experiment, the researchers used many compounds, for example, Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6Product Details of 40571-86-6).

Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Product Details of 40571-86-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts