Month: January 2023

Metabolomics reveals changes in metabolite composition of duck eggs under the impact of long-term storage was written by Liu, Hehe;Yang, Qinglan;Guo, Rui;Hu, Jiwei;Tang, Qian;Qi, Jingjing;Wang, Jiwen;Han, Chunchun;Zhang, Rongping;Li, Liang. And the article was included in Journal of the Science of Food and Agriculture in 2022.Formula: C4H10O4 This article mentions the following:

Eggs are essential food sources as they provide low cost and high nutritional content of animal protein. The preservation period is one of the apparent factors affecting egg quality. Previous studies based on traditional detection techniques demonstrated that storage period would significantly influence egg weight, eggshell weight, albumen height, haugh unit (HU) and albumen viscosity. Herein, we employed non-targeted metabolome technol. to reveal the comprehensive changes in metabolite composition in duck eggs under the impacts of storage period. The results showed that the primary metabolites in the yolk of duck eggs are amino acids, carbohydrates and lipids. In contrast, the primary metabolites in the albumen are amino acids, benzene and indoles. We screened 43 and 16 different metabolites, resp., in the albumen and yolk of duck eggs with different preservation periods. In addition, kyoto encyclopedia of genes and genomes (KEGG) enrichment was performed, and the results showed that various nutrients were degraded in the egg after preservation, thus affecting the quality of duck eggs. These nutrients included amino acids, fatty acids, nucleotides, sugars and vitamins; meanwhile, ammonia, biogenic amines and some flavor substances were produced, affecting the quality of the eggs. Ourfindings can contribute to a holistic understanding of metabolite composition changes in duck eggs during deterioration in storage. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6Formula: C4H10O4).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Formula: C4H10O4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Redox-neutral ortho-C-H amination of pinacol arylborates via palladium(II)/norbornene catalysis for aniline synthesis was written by Chen, Shuqing;Wang, Peng;Cheng, Hong-Gang;Yang, Chihui;Zhou, Qianghui. And the article was included in Chemical Science in 2019.Computed Properties of C12H16BBrO2 This article mentions the following:

A palladium(II)/norbornene cooperative catalysis enabled redox-neutral ortho-C-H amination of pinacol aryl- or heteroarylborates for the synthesis of structurally diverse anilines was reported. The method was scalable, robust (tolerance of air and moisture), phosphine ligand-free and compatible with a wide range of functionalities. These practical features made this reaction amenable for industry. A plethora of synthetically very useful halogenated anilines which often cannot be prepared via other transition-metal-catalyzed aminations were readily produced using this method. Particularly, the orthogonal reactivity between pinacol arylborates and aryl iodides was demonstrated. Preliminary deuterium-labeling studies revealed a redox-neutral ipso-protonation mechanism of this process, which will surely inspire the future development of this field. Overall, the exceptionally broad scope (47 examples) and reliability of this procedure, together with the wide availability of pinacol arylborates made this chem. a valuable addition to the existing methods for aniline synthesis. In the experiment, the researchers used many compounds, for example, 2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4Computed Properties of C12H16BBrO2).

2-(4-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (cas: 68716-49-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Computed Properties of C12H16BBrO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

New 2D Assemblage of Supertetrahedral Chalcogenide Clusters with Tetravalent-Metal-Induced Interrupted Sites was written by Wu, Zhou;Luo, Min;Xue, Chaozhuang;Zhang, Jiaxu;Lv, Jing;Wang, Xiang;Wu, Tao. And the article was included in Crystal Growth & Design in 2019.Electric Literature of C4H11NO This article mentions the following:

Reported here are two new layered chalcogenide frameworks built from tetravalent-metal-induced triconnected supertetrahedral T3-InSnS clusters. This work demonstrates the significant role of tetravalent metal ion in building new 2D chalcogenide frameworks with the interrupted sites. Moreover, both chalcogenide materials show good performance on the photodegradation of methyl blue (MB). In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Electric Literature of C4H11NO).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C4H11NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of 1,8-terpine hydrate from by-products of eucalyptus oil was written by Li, Bingqiang;Zhuang, Haiqi. And the article was included in Zhongguo Yiyao Gongye Zazhi in 1993.Application In Synthesis of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate This article mentions the following:

Treatment of eucalyptus oil byproduct containing 65% α- and β-pinene with 25-40% H₂SO₄ and tween-80 at room temperature for 16 h gave 82.2% 1,8-terpine hydrate. In the experiment, the researchers used many compounds, for example, rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6Application In Synthesis of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate).

rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate (cas: 2451-01-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of rel-(1s,4s)-4-(2-Hydroxypropan-2-yl)-1-methylcyclohexanol hydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluation and Efficacy Modified Carvacrol and Anti-cancer Peptide Against Cell Line Gastric AGS was written by Elahi, Mona Ghods;Hekmati, Malak;Esmaeili, Davoud;Ziarati, Parisa;Yousefi, Mohamad. And the article was included in International Journal of Peptide Research and Therapeutics in 2022.Category: alcohols-buliding-blocks This article mentions the following:

Cancer is a complex of malignant cell growth and is one of the most challenging issues worldwide. This study aimed to design, determine, and synthesize a modified carvacrol-containing anticancer peptide sequence and its anti-cancer properties investigated against gastric cancer cell line by Real-Time RT PCR technique. Anticancer peptide sequence designed by ACAN bioinformatics software. Modified carvacrol structure designed by bioinformatics software and the anti-cancer sequence added to it. After determining the chem. and structural properties and modeling by bioinformatics software the compound was synthesized. Then, an MTT test was performed on the gastric cancer cell line. In the next step, the AGS cancer cell is exposed to the MTT concentration of the compound in a culture medium. Then, mRNA is extracted from treatment-exposed cancer cells and treatment-free cell lines, and cDNA was then synthesized from mRNA. The effect of the compound on caspase3 and bcl2 apoptosis genes is investigated by Real-Time RT PCR. Alkylation of o-cresol with isopropanol over AlCl₃ as an efficient catalyst leads to the appropriate preparation of carvacrol with proper yields (75.6). Results showed that carvacrol accompanied by Anticancer peptide at a concentration of 2.5 mg/mL had cytotoxic effects on the cervical. The inhibitory effects of carvacrol and anticancer peptide increased against inhibition of the Bax gene by 256-fold and caspase 3 by 32-fold and bcl2 decreased by eightfold. Because of the anti-apoptotic properties of modified carvacrol-containing anticancer peptide, it can be used to inhibit cancer cells as a therapeutic supplement and prevention. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Category: alcohols-buliding-blocks).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chemo- and Stereoselective Synthesis of Fluorinated Amino Alcohols through One-pot Reactions using Alcohol Dehydrogenases and Amine Transaminases was written by Gonzalez-Martinez, Daniel;Gotor, Vicente;Gotor-Fernandez, Vicente. And the article was included in Advanced Synthesis & Catalysis in 2020.SDS of cas: 49669-14-9 This article mentions the following:

A series of amino alcs. have been prepared in a chemo-, diastereo- and enantioselective fashion starting from the corresponding (het)aryl diketones, avoiding tedious chem. protection and deprotection steps. Different alc. dehydrogenases have been able to selectively reduce the more reactive trifluoroacetyl groups under optimized conditions, while amine transaminases catalyzed the biotransamination of the less hindered acetyl groups. Based on the different reactivity of the acetyl and trifluoroacetyl groups, the design of sequential and concurrent cascades was investigated. The proper selection of the enzymes permits the synthesis of amino alc. stereoisomers in high to excellent yields (86->99% conversion) and remarkable stereocontrol (up to >99% de and >99% ee) using an aqueous medium and mild reaction conditions. In the experiment, the researchers used many compounds, for example, 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9SDS of cas: 49669-14-9).

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine (cas: 49669-14-9) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.SDS of cas: 49669-14-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Optimization of the identification of chemical compounds by energy-dispersive x-ray fluorescence spectrometry and subsequent multivariate analysis was written by Kessler, T.;Hoffmann, P.;Greve, T.;Ortner, H. M.. And the article was included in X-Ray Spectrometry in 2002.Recommanded Product: Calcium 2-hydroxypropanoate pentahydrate This article mentions the following:

Chem. compounds were measured by EDXRF (with three different types of instrumentation). The spectra were used to evaluate discriminant anal. classification. The chem. compounds were primarily classified by their fluorescence signals. Valuable addnl. information was obtained from the spectral range of the Compton and the Rayleigh scattering regions using multivariate methods (e.g. PCA and RDA). An improvement over earlier work was achieved considering different parameters such as the position of the sample, the grain size of a chem. compound and the thickness of the package wall. In the experiment, the researchers used many compounds, for example, Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5Recommanded Product: Calcium 2-hydroxypropanoate pentahydrate).

Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: Calcium 2-hydroxypropanoate pentahydrate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

New lignin-based hybrid materials as functional additives for polymer biocomposites: From design to application was written by Jedrzejczak, Patryk;Puszka, Andrzej;Kubiak, Adam;Podkoscielna, Beata;Klapiszewski, Lukasz. And the article was included in International Journal of Biological Macromolecules in 2021.Synthetic Route of C16H26O7 This article mentions the following:

Within this study, the ZrO₂/lignin and ZrO₂-SiO₂/lignin hybrid materials were obtained for the first time. The mech. grinding method was used for this purpose. In order to determine the properties of obtained lignin-based hybrids and the components used to produce them, as well as to evaluate the efficiency of their preparation, the authors used such research techniques as SEM (SEM), Fourier transform IR spectroscopy (FTIR), elemental anal., porous structure anal. and thermal stability assessment (TGA/DTG). The next step involved using the components and produced hybrid materials as polymer fillers for poly(Me methacrylate) (PMMA). The obtained lignin-based hybrid biocomposites have then been thoroughly characterized using gel permeation chromatog. (GPC), differential scanning calorimetry (DSC), dynamic mech. anal. (DMA) and hardness testing. All the conducted tests confirm the possibility of using the obtained bio-based products in practice, within the widely understood construction industry, for producing durable building facades or noise barriers, among others. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Synthetic Route of C16H26O7).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Synthetic Route of C16H26O7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Allergic contact dermatitis caused by acrylates and methacrylates – a 7-year study was written by Ramos, Leonor;Cabral, Rita;Goncalo, Margarida. And the article was included in Contact Dermatitis in 2014.Recommanded Product: 109-17-1 This article mentions the following:

Summary : Backgound : Allergic contact dermatitis (ACD) caused by (meth)acrylates is traditionally an occupational disease among dentists, printers, and fiberglass workers. With the use of artificial nails, cases have been reported both in nail technicians and in users. Objectives : The aims of this study were to characterize ACD caused by (meth)acrylates, identify the responsible allergens, and assess the sensitivity of the patch test with 2-hydroxyethyl methacrylate (HEMA) for diagnosis. Methods : An observational and retrospective study (Jan. 2006-Apr. 2013) was performed, evaluating and correlating epidemiol. and clin. parameters and pos. patch test results with (meth)acrylates. Results : Among 2263 patch tested patients, 122 underwent aimed testing with an extended (meth)acrylate series, and 37 showed pos. and relevant reactions. Twenty-five cases (67.6%) were occupational. Hand eczema with pulpitis was observed in 32 patients. Twenty-eight cases were related to artificial nails, 3 were related to dental materials, and 2 were industrial workers. Oral lesions associated with dental prostheses were observed in 4 patients. Thirty-one patients reacted to more than one (meth)acrylate. In our sample, beauty technicians working with artificial nails were the most affected group (80% of occupational cases). Conclusion : HEMA detected 80.6% of our cases, and may be considered a good screening allergen. However, to perform an accurate diagnosis, it is safer to use a broader series of allergens. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Recommanded Product: 109-17-1).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 109-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sugar alcohols have the potential as bee-safe baits for the common wasp was written by Neupert, Stefanie;Jandt, Jennifer M.;Szyszka, Paul. And the article was included in Pest Management Science in 2022.SDS of cas: 149-32-6 This article mentions the following:

Pest insects are often baited with poisoned feeding stimulants, the most common of which are sugars. However, sugars are attractive for most animal species, which makes it difficult to target only a specific pest insect species. Here, we assessed different sugar alcs. for their potential as more species-selective feeding stimulants for pest insects. We tested the attractiveness of the sugar alcs. sorbitol, xylitol and erythritol with a capillary feeder assay in wasps (as potential pest insects, because introduced wasps are a pest in many regions) and bees (as non-target insects). For the common wasp (Vespula vulgaris), sorbitol and xylitol acted as nutritive feeding stimulants, and erythritol acted as a non-nutritive feeding stimulant. For the buff-tailed bumble bee (Bombus terrestris), sorbitol acted as a feeding stimulant, while for the honey bee (Apis mellifera), none of the sugar alcs. acted as feeding stimulant. The species-specific preferences for sugar alcs. suggest their potential as species-selective insect baits. The wasp-specific preference for xylitol suggests its potential as a bee-safe alternative to sugar-containing bait for controlling the common wasp. 2022 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chem. Industry. In the experiment, the researchers used many compounds, for example, (2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6SDS of cas: 149-32-6).

(2R,3S)-rel-Butane-1,2,3,4-tetraol (cas: 149-32-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.SDS of cas: 149-32-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts