Month: December 2022

Du, Minchen published the artcileAn efficient and recyclable AgNO3/ionic liquid system catalyzed atmospheric CO2 utilization: Simultaneous synthesis of 2-oxazolidinones and α-hydroxyl ketones, Product Details of C8H14O, the main research area is oxazolidinone hydroxyl ketone preparation green chem; propargyl alc aminoethanol carbon dioxide three component reaction; silver nitrate ethyl methylimidazolium acetate catalyst.

Oxazolidinones I (R = (CH2)2OH, Bn, 4-MeC6H4CH2, etc.) and α-hydroxyl ketones CH3C(O)C(R1)(R2)OH (R1 = Me, Et; R2 = Me, Et, i-Bu, Ph; -R1R2- = -(CH2)5-) are two series of fine chems. that have been generally utilized in biol., pharmaceutical, and synthetic chem. Herein, a AgNO3/ionic liquid (IL) catalytic system was developed for the simultaneous synthesis of these compounds through the atom-economical three-component reactions of propargyl alcs., 2-aminoethanols, and CO2. Notably, this system behaved excellent catalytic activity with the lowermost metal loading of 0.25 mol%. Meanwhile, it is the first reported metal-catalyzed system that could efficiently work under atm. CO2 pressure and be recycled at least five times. Evaluation of the green metrics proved the AgNO3/IL-catalyzed processes to be relatively more sustainable and greener than the other Ag-catalyzed examples. Further mechanistic investigations revealed the derivative active species of N-heterocyclic carbene (NHC) silver complexes and CO2 adducts generated during the process. Subsequently, their reactivity in this reaction was assessed for the first time, which was finally identified as beneficial for the catalytic activity.

Journal of Catalysis published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Product Details of C8H14O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gu, Ai-Ling published the artcileHighly Efficient Conversion of Propargylic Alcohols and Propargylic Amines with CO2 Activated by Noble-Metal-Free Catalyst Cu2O@ZIF-8, Product Details of C8H14O, the main research area is alkylidene cyclic carbonate oxazolidinone preparation; propargylic alc amine carbon dioxide cycloaddition; metalorganic framework ZIF8 encapsulated cuprous oxide nanoparticle preparation catalyst; CO2; Metal-Organic Frameworks; Noble-Metal-Free; Propargylic Alcohols; Propargylic Amines.

The cyclization reactions of propargylic alcs. and propargylic amines with CO2 are important in industrial applications, but it was a great challenge that non-noble-metal catalysts catalyzed both reactions under mild conditions. Herein, the catalyst Cu2O@ZIF-8 was prepared by encapsulating Cu2O nanoparticles into robust ZIF-8, and it can effectively catalyze the cyclization of both propargylic alcs. and propargylic amines with CO2 into valuable α-alkylidene cyclic carbonates and oxazolidinones with turnover numbers (TONs) of 12.1 and 19.6, which can be recycled at least five times. The mechanisms were further uncovered by NMR, FTIR, 13C isotope-labeling experiments and DFT calculations, in which Cu2O and DBU can synergistically activate the C≃C bond and the hydroxy/amino group of substrates. Importantly, it is the first example of a noble-metal-free catalyst that can catalyze both propargylic alcs. and propargylic amines with CO2 simultaneously.

Angewandte Chemie, International Edition published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Product Details of C8H14O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Xiao published the artcileReduced Graphene Oxide Supported Ag Nanoparticles: An Efficient Catalyst for CO2 Conversion at Ambient Conditions, Category: alcohols-buliding-blocks, the main research area is reduced graphene oxide supported silver nanoparticle catalyst preparation; alkylidene carbamate oxazolidinone preparation; propargylic alc amine carbon dioxide carboxylative cyclization.

A highly efficient carboxylative cyclization of propargylic alcs. with CO2 under atm. pressure catalyzed by silver (0) nanoparticles decorated reduced graphene oxide (Ag-rGO) is reported. Ag-rGO was fully characterized by scanning electron microscope spectra (SEM), transmission electron microscopy (TEM), Fourier transform IR (FT-IR) spectra, Raman spectra and XPS. Notably, Ag-rGO can be also applied to the construction of other value-added chems. (β-oxopropylcarbamates and 2-oxazolidinones) from CO2 at ambient conditions. In addition, Ag-rGO is stable and reusable, which shows the potential for the practical application for CO2 capture and utilization (CCU).

ChemCatChem published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tang, Minhao published the artcileA CO2-mediated base catalysis approach for the hydration of triple bonds in ionic liquids, HPLC of Formula: 107-54-0, the main research area is carbonyl compound preparation green chem; nitrile alkyne hydration carbon dioxide ionic liquid.

Herein, a CO2-mediated base catalysis approach for the activation of triple bonds in ionic liquids (ILs) with anions that can chem. capture CO2 (e.g., azolate, phenolate, and acetate), which can achieve hydration of triple bonds to carbonyl chems. is reported. It is discovered that the anion-complexed CO2 could abstract one proton from proton resources (e.g., IL cation) and transfer it to the CN or CC bonds via a six-membered ring transition state, thus realizing their hydration. In particular, tetrabutylphosphonium 2-hydroxypyridine shows high efficiency for hydration of nitriles and CC bond-containing compounds under a CO2 atmosphere, affording a series of carbonyl compounds in excellent yields. This catalytic protocol is simple, green, and highly efficient and opens a new way to access carbonyl compounds via triple bond hydration under mild and metal-free conditions.

Green Chemistry published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, HPLC of Formula: 107-54-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qiu, Jikuan published the artcileCu(I)/ionic liquids promote the conversion of carbon dioxide into oxazolidinones at room temperature, Safety of 3,5-Dimethylhex-1-yn-3-ol, the main research area is oxazolidinone preparation green chem; propargylic alc amine carbon dioxide three component copper catalyst; carbon dioxide; catalysis; ionic liquids; oxazolidinones.

A one-pot three component reaction of propargylic alcs. HOC(R1)(R2)CCH [R1 = Me, Et, isobutyl; R2 = Me; R1 = R2 = -(CH2)5-], amines R3NH2 (R3 = n-Bu, iso-Bu, cyclohexyl, n-hexyl) and CO2 that can proceed in an atom economy and environmentally benign manner by combination of CuI and tetrabutylphosphonium imidazol ([P4444][Im]) as a catalyst was described. Catalysis studies indicate that this catalytic system is an effective catalyst for the conversion of CO2 into oxazolidinones I at room temperature and ambient pressure without any solvent. The results provide a useful way to design novel noble metal-free catalyst systems for the transformation of CO2 into other valuable compounds

Molecules published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Safety of 3,5-Dimethylhex-1-yn-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Mingzhe published the artcileChemical Fixation of CO2 Using Highly Dispersed Cu on Hierarchically Porous N-Doped Carbon, Recommanded Product: 3,5-Dimethylhex-1-yn-3-ol, the main research area is carbon dioxide fixation copper nitrogen doped porous carbon catalyst; oxide carbon fixation copper nitrogen doped porous carbon catalyst; N-doped carbon; carbon dioxide; copper catalyst; coupling reaction; hierarchical porosity.

A heterogeneous catalyst of highly dispersed Cu (Cu/NHPC) supported on hierarchically porous N-doped C (NHPC) can efficiently promote CO2 fixations to oxazolidinones and β-oxopropylcarbamates. The obtained NHPC, assembled by ultrathin N-doped C nanosheets with a 3-dimensional (3D) structure, is readily prepared by pyrolysis of a N-containing polymer gel (NPG) in the presence of an activator of K bicarbonate (KHCO3). The resulting NHPC shows specific Brunauer-Emmet-Teller (BET) surface areas ≤2054 m2 g-1 with a mean micro/mesopore size of 0.55/3.2 nm and a broad macropore size distribution from 50 to 230 nm. The Cu/NHPC can efficiently promote 3-component coupling of CO2, amines, and propargyl alcs. for syntheses of various oxazolidinones and β-oxopropylcarbamates with yields ≤99% and a wide substrate scope. The Cu/NHPC exhibits excellent recyclability in CO2-to-oxazolidinone transformation during 9-time recycling. The research develops an NHPC-based heterogeneous Cu catalyst for green transformation of CO2.

ACS Applied Materials & Interfaces published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Recommanded Product: 3,5-Dimethylhex-1-yn-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chang, Liping published the artcileFixing CO2 into β-oxopropylcarbamates in neat condition by ionic gelation/Ag(I) supported on dendritic fibrous nanosilica, Application of 3,5-Dimethylhex-1-yn-3-ol, the main research area is recyclable silver supported dendritic fibrous nanosilica ionic gelation preparation; amine propargyl alc carbon dioxide silica three component coupling; oxo propyl carbamate preparation.

A novel approach to produced a novel nanocatalyst, AgBr supported on an ionic gelation (IG)-based nanomaterial was developed through the aqueous coprecipitation approach for the dendritic fibrous nanosilica (DFNS) production and the wet impregnation method for IG coating, taking into account TPP as the crosslinking agent. In addition, DFNS/IG@Ag(I) was heterogeneous features that contributed to the quick improvement of the catalyst by filtration separation The catalytic activity of DFNS/IG@Ag(I) was examined to synthesize β-oxopropylcarbamates through a multicomponent coupling of CO2, amines and propargyl alcs. in moderate conditions. The DFNS/IG@Ag(I) NPs were completely investigated by taking advantage of TG, TEM, FESEM and FT-IR spectroscopy anal. The DFNS/IG@Ag(I) nanocatalyst indicated high stability in the reaction for five cycles without considerable loss of some properties like activity, which could be because of the high loading of IG on the catalyst surface.

RSC Advances published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 107-54-0 belongs to class alcohols-buliding-blocks, name is 3,5-Dimethylhex-1-yn-3-ol, and the molecular formula is C8H14O, Application of 3,5-Dimethylhex-1-yn-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cibotaru, Dorina published the artcileComparison of liquid-liquid extraction, microextraction and ultrafiltration for measuring free concentrations of testosterone and phenytoin, Related Products of alcohols-buliding-blocks, the main research area is testosterone phenytoin liquid extraction microextraction ultrafiltration; albumin; free concentration; liquid–liquid extraction; phenytoin; plasma protein binding; solid-phase microextraction; testosterone; ultrafiltration.

The purpose of the study was to find methods suitable for measuring the free concentrations of testosterone and phenytoin. Sample solutions of the compounds in buffer and human albumin were processed using liquid-liquid extraction, microextraction and ultrafiltration and analyzed by LC-MS/MS. Liquid-liquid extraction with di-Bu phthalate provided complete extraction from buffer solutions and partial extraction from albumin samples. Spintip C18 devices provided exhaustive extraction from buffer and albumin samples. Spintip C8 devices offered complete extraction from buffer and approx. 50% recovery from albumin samples. Centrifree ultrafiltration devices showed high recovery of free concentrations from all the samples, while Amicon and Nanosep devices provided partial recovery. Spintip C8 and Centrifree devices proved useful for measuring free concentrations

Bioanalysis published new progress about Human albumins Role: AMX (Analytical Matrix), ANST (Analytical Study). 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Elbelazi, Asma published the artcileDevelopment of a homogenous assay based on fluorescent imprinted nanoparticles for analysis of nitroaromatic compounds, Quality Control of 7575-23-7, the main research area is nitroarom compound fluorescent imprinted nanoparticle homogenous assay.

Herein we describe the development of a homogeneous assay for the detection of 4-nitroaniline (4-NA) and 2,4-dinitroaniline (2,4-diNA). This assay relies on fluorescent molecularly imprinted nanoparticles (nanoMIPs) which, upon interaction with the target analytes, generate a reduction in fluorescence emission intensity (quenching). This is due to a responsive fluorescent monomer (N-2-propenyl-(5-dimethylamino)-1-naphthalene sulfonamide) employed in the manufacture of the nanoMIPs which, by virtue of the imprinting process, is capable of selective interaction with the target analyte, thus giving rise to a quenching effect. Selectivity experiments showed excellent recognition properties toward the target mol. Under optimal conditions, the fluorescence intensity of these nanoMIPs decreased as the concentration of the imprinted analyte increased from 10 nM to 2.71 μM. A linear relation between the neg. logarithm of 4-NA or 2,4-diNA concentrations and the fluorescence intensity for both nanosystems was found (R2 = 0.991 and R2 = 0.9895), with excellent sensitivity (limit of detection (LOD) = 7 and 6 nM, resp.). Furthermore, both nanosystems have been successfully applied for detection of 4-NA or 2,4-diNA in tap water, with recoveries between 90% to 100.6% and 92% to 100.3%, resp. Thanks to the versatility of the imprinting process, this nanosystem holds the potential for further development of several optical sensors for many other compounds [Figure not available: see fulltext.]

Nano Research published new progress about Aromatic nitro compounds Role: ANT (Analyte), ANST (Analytical Study). 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Quality Control of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Hong published the artcileImproved Process for the Palladium-Catalyzed C-O Cross-Coupling of Secondary Alcohols, Application of 3-Pentanol, the main research area is aromatic ether preparation; aryl halide secondary alc coupling reaction palladium catalyst.

An improved protocol for the Pd-catalyzed I C-O cross-coupling of secondary alcs. ROH (R = butan-2-yl, 2,2,2-trifluoro-1-phenylethyl, cyclopropyl(phenyl)methyl, etc.) is described. The use of biaryl phosphine as the ligand was key to achieving efficient cross-coupling of (hetero)aryl halides ArX (X = Cl, Br; Ar = 4-tert-butylphenyl, naphthalen-1-yl, 4-methylpyridin-2-yl, etc.) with only a 20% molar excess of the alc. Addnl., an unusual reactivity difference between an electron-rich aryl bromide and the analogus aryl chloride, and deuterium-labeling suggested that currently unidentified pathways for reduction play an important role in explaining this disparity were observed

Organic Letters published new progress about Aromatic ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Application of 3-Pentanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts