Month: December 2022

Alboofetileh, Mehdi published the artcileEffect of different non-conventional extraction methods on the antibacterial and antiviral activity of fucoidans extracted from Nizamuddinia zanardinii, Related Products of alcohols-buliding-blocks, the main research area is Nizamuddinia antibacterial antiviral fucoidan non conventional extraction method; Antibacterial activity; Antiviral activity; Extraction methods; Fucoidans; Nizamuddinia zanardinii; Non-conventional techniques.

In the current study, fucoidans from brown alga Nizamuddinia zanardinii were isolated with conventional and non-conventional extraction procedures to evaluate the effects of recently introduced technologies on biochem. characteristics and saccharide composition of the extracts, along with their antibacterial, antiviral and cytotoxic properties. The results demonstrated that subcritical water extraction showed the highest fucoidans yield (13.15%), while the lowest yield was obtained using ultrasound extraction method (3.6%). The polysaccharide chains consisted of fucose, galactose, glucose, mannose and xylose, whose molar percentages differed according to the extraction method used. The weight mean average mol. weight of fucoidans varied between 444 and 1184 kDa. The FT-IR spectroscopy confirmed the presence of sulfate esters by bending vibration of C-O-S and stretching vibration of S=O peaks at 818 and 1250 cm-1, resp. Antibacterial assays showed that microwave- and subcritical water-extracted fucoidans inhibited the growth of E.coli and that enzyme-ultrasound, ultrasound-microwave and subcritical water extracted fucoidans exhibited inhibitory effects against P. aeruginosa at 2 mg/mL. Antiviral studies revealed that all the extracted fucoidans exerted strong antiviral activity against HSV-2 infection, with EC50 values in the 0.027-0.123 μg/mL range; indeed the viscozyme-extracted macromols. displayed the best selectivity index.

International Journal of Biological Macromolecules published new progress about Agarum clathratum. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Guo published the artcileExtraction, structural characterization, and immunobiological activity of ABP Ia polysaccharide from Agaricus bisporus, Quality Control of 59-23-4, the main research area is Agaricus polysaccharide rhamnose arabinose splenocyte proliferation immunoregulatory activity; Agaricus bisporus polysaccharides; Extraction and structure; Immunobiological activity.

The extraction, purification, immunobiol. activities, and structure of Agaricus bisporus polysaccharides (ABP) were investigated. Especially we purified and identified the polysaccharides with the highest in vitro immunobiol. activity. The extraction conditions of ABP were optimized using single factor and orthogonal experiment ABP Ia was screened after double purification with DEAE-52 and Sephadex G-200 and showed the best immunoregulatory activity. UV spectra anal. and high-performance gel permeation chromatog. results indicated that the ABP Ia fraction did not contain any proteins or nucleotides and was a homogeneous polysaccharide with a relative mol. weight of 784 kDa. Gas chromatog. mass spectroscopy results showed that ABP Ia was a heteropolysaccharide consisting of ribose, rhamnose, arabinose, xylose, mannose, glucose, and galactose at a molar ratio of 2.08:4.61:2.45:22.25:36.45:89.22:1.55. FT-IR and periodic acid oxidation anal. indicated that ABP Ia was an α-pyran polysaccharide composed of 1 → 2 and 1 → 4 glycosidic bonds, as well as a possible 1 → 3 glycosidic bond. Furthermore, at. force microscopy revealed that ABP Ia polysaccharide chains twisted to form a rod-like architecture and, at a 5% concentration, aggregated into a tight structure similar to the shape of a stone forest. These findings identify ABP Ia as a potential functional food ingredient or pharmaceutical for immunoregulation.

International Journal of Biological Macromolecules published new progress about Agaricus bisporus. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Quality Control of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Feng, Yuqin published the artcileRecent advances in Agaricus bisporus polysaccharides: Extraction, purification, physicochemical characterization and bioactivities, Category: alcohols-buliding-blocks, the main research area is review Agaricus polysaccharide galactose extraction physicochem property food composition.

Agaricus bisporus (A. bisporus), known as a cultivated mushroom or button mushroom, is a very important edible and medicinal basidiomycete fungus. The numerous health benefits of A. bisporus may be related to their polysaccharides, which have significant dietary value and bioactivity, including immunity stimulation and high antioxidant, anticancer, hepatoprotection, anti-inflammation and anti-obesity functions. In general, the extraction method of A. bisporus polysaccharides (ABPs) is relatively simple, and the yield from enzyme-assisted extraction is the highest among various extraction methods. The monosaccharide composition anal. revealed that ABPs mainly consist of glucose, galactose, fucose and xylose, which each have a backbone composed of (1→6)- and (1→4)-linked α-glucan or alternating (1→4)- and (1→6)-linked β-glucan. The biol. activity of ABPs may vary significantly depending on their source, composition, structural properties, and purity, and it is highly correlated with mol. weight (MW) and the monosaccharide components. Therefore, this review aims to introduce the extraction methods, chem. structure, and biol. activity of ABPs which may provide a theor. basis for the further development and utilization of polysaccharides and have important reference value for the future study of the relationship between structural features and biol. activities.

Process Biochemistry (Oxford, United Kingdom) published new progress about Agaricus bisporus. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Coff, Lachlan published the artcileIdentifying glycan motifs using a novel subtree mining approach, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is glycan motif subtree mining algorithm; Carbohydrate; Frequent subtree mining; Glycan; Glycobiology; Machine learning; Microarray; Motif.

Glycans are complex sugar chains, crucial to many biol. processes. By participating in binding interactions with proteins, glycans often play key roles in host-pathogen interactions. The specificities of glycan-binding proteins, such as lectins and antibodies, are governed by motifs within larger glycan structures, and improved characterisations of these determinants would aid research into human diseases. Identification of motifs has previously been approached as a frequent subtree mining problem, and we extend these approaches with a glycan notation that allows recognition of terminal motifs. In this work, we customised a frequent subtree mining approach by altering the glycan notation to include information on terminal connections. This allows specific identification of terminal residues as potential motifs, better capturing the complexity of glycan-binding interactions. We achieved this by including addnl. nodes in a graph representation of the glycan structure to indicate the presence or absence of a linkage at particular backbone carbon positions. Combining this frequent subtree mining approach with a state-of-the-art feature selection algorithm termed min.-redundancy, maximum-relevance (mRMR), we have generated a classification pipeline that is trained on data from a glycan microarray. When applied to a set of commonly used lectins, the identified motifs were consistent with known binding determinants. Furthermore, logistic regression classifiers trained using these motifs performed well across most lectins examined, with a median AUC value of 0.89. We present here a new subtree mining approach for the classification of glycan binding and identification of potential binding motifs. The Carbohydrate Classification Accounting for Restricted Linkages (CCARL) method will assist in the interpretation of glycan microarray experiments and will aid in the discovery of novel binding motifs for further exptl. characterization.

BMC Bioinformatics published new progress about Agaricus bisporus. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Name: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Abedsoltan, Hossein published the artcileAryl sulfonic acid catalysts: Effect of pendant group structure on activity in hydrolysis of polyethylene terephthalate, HPLC of Formula: 111-87-5, the main research area is aryl sulfonic acid catalyst hydrolysis polyethylene terephthalate.

A series of aryl sulfonic acids were tested as catalysts for acid hydrolysis occurring at the surface of poly(ethylene) terephthalate (PET) particles. Specifically, p-toluenesulfonic acid monohydrate (PTSA), 2-naphthalenesulfonic acid (2-NSA), and 1,5-naphthalenedisulfonic acid tetrahydrate (1,5-NDSA) were chosen to provide sulfonic acid active groups and varying hydrophobic func tionality. The effect of catalyst concentration and reaction temperature on PET hydrolysis rate was studied. The aryl sulfonic acid catalysts exhibited much higher rates of PET hydrolysis than the mineral acid, H2SO4. At 150°C and 4 M catalyst, the time required to achieve more than 90% TPA yield was 3, 3, and 8 h, and 18 h for (PTSA), (2-NSA), (1,5-NDSA), and H2SO4, resp. Et acetate hydrolysis was performed as a model reaction to probe the activity of the catalysts in homogenous reactions to compare with the heterogeneous hydrolysis reaction occurring at the PET surface. The higher catalytic activities for PET hydrolysis of the PTSA, 2-NSA, and 1,5-NDSA than H2SO4 was attributed to improved wetting by the reaction media and affinity of the aryl sulfonic acid catalysts for the PET surface.

Journal of Applied Polymer Science published new progress about Activation energy. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, HPLC of Formula: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bongiardina, Nicholas J. published the artcileSubstituted Thiols in Dynamic Thiol-Thioester Reactions, Formula: C17H28O8S4, the main research area is thiol dynamic thioester.

The thiol-thioester reaction has emerged as a promising method for developing covalent adaptable networks (CANs) due to its ability to exchange rapidly under low temperature conditions in a number of solvents, orthogonality among other functional groups, and tunability. Here, the effects of thiol substitution (i.e., primary vs secondary) were assessed with respect to their reactivity in two dynamic thioester reactions: the thiol-thioester exchange and the reversible thiol-anhydride addition Model NMR experiments were conducted using small-mol. compounds to observe how polymers of similar components would behave in thiol-thioester exchange. It was determined that the Keq was near unity for mixtures of primary thiols and secondary thioesters, and vice versa, in both a polar solvent, DMSO-d6, and at most slightly favors primary thioesters in a relatively nonpolar solvent, CDCl3. Dielec. spectroscopy and stress relaxation experiments were used to determine the relaxation times and activation energies of the two thioester-containing networks: Thiol-ene networks, which undergo thioester exchange, displayed activation energies of 73 and 71 kJ/mol from dielec. measurements and 36 and 53 kJ/mol from stress relaxation for the primary and secondary thiols, resp. Thiol-anhydride-ene networks, which undergo both thioester exchange and reversible thiol-anhydride addition, displayed activation energies of 94 and 114 kJ/mol from dielec. and 111 and 139 kJ/mol from stress relaxation for primary and secondary thiols, resp. In both types of networks, the secondary thioester-based networks demonstrated slower dynamics as compared to the same primary network by at least one order of magnitude. In the anhydride network, the secondary thiol also biased the dynamics toward reversible addition

Macromolecules (Washington, DC, United States) published new progress about Activation energy. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Formula: C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Isogai, Taketo published the artcileCritical Effects of Branch Numbers at the Cross-Link Point on the Relaxation Behaviors of Transesterification Vitrimers, COA of Formula: C17H28O8S4, the main research area is relaxation behavior transesterification vitrimer.

Vitrimers are functional crosslinked materials, exhibiting reprocessability, recyclability, and healability, and thus these are expected for application as sustainable materials. The functionalities of vitrimers are attributable to their associative bond exchange mechanism that is activated at a certain high temperature The construction of a tuning method for the bond exchange properties must be useful for coming practical application of the vitrimer concept. Here, we prepare transesterification-based vitrimers via the thiol-epoxy click reaction to elucidate the essential effects of the branch numbers (f) at the crosslink point on their bond exchange properties, where f can be readily tuned via the functionality of the starting materials. The temperature-ramp creep and stress-relaxation tests then demonstrate that the vitrimer properties, such as the softening and stress-relaxation behaviors, vary depending on f. The exptl. results derive some empirical relationships between f and the relaxation time and between f and activation energy of the bond exchange. In addition, the relaxation behavior of the vitrimer network with mixed f is investigated in the final section, showing the relaxation rate can be determined by the harmonic mean of relaxation time weighted by the mole fraction of the network components having different f. Overall, this study demonstrates that the design of a proper f is crucial to obtain the desired properties of vitrimers.

Macromolecules (Washington, DC, United States) published new progress about Activation energy. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, COA of Formula: C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Stalin, Sanjuna published the artcileAchieving uniform lithium electrodeposition in cross-linked poly(ethylene oxide) networks: “”soft”” polymers prevent metal dendrite proliferation, Name: Pentaerythritol tetra(3-mercaptopropionate), the main research area is lithium electrodeposition crosslinked polyethylene oxide electrolyte.

Lithium electrodeposition in uniformly porous, nanostructured media formed in cross-linked poly(ethylene oxide) polymer networks enabled by thiol-ene click chem were investigated. Using galvanostatic strip-plate experiments along with SEM and operando visualization techniques, we critically assess the effectiveness of these materials in enabling uniform, planar deposition of lithium. Thiol-ene click networks that host a liquid electrolyte in their pores are more effective than their liquid electrolyte or solid polymer network components in regulating Li deposition at both the nucleation and growth phases. It is shown further that compressive interfacial stresses imparted by the networks during electrodeposition may serve to augment surface tension to enable uniform Li electrodeposition. The practical relevance of these electrolytes is demonstrated in full-cell battery configurations with excellent long-term stability.

Macromolecules (Washington, DC, United States) published new progress about Activation energy. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Name: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Moradi, Sasan published the artcileEpoxy composites filled with boron nitride: cure kinetics and the effect of particle shape on the thermal conductivity, SDS of cas: 7575-23-7, the main research area is epoxy resin boron nitride composite particle size thermal conductivity.

Thermally conducting and elec. insulating materials have been prepared by filling an epoxy-thiol system with boron nitride (BN) particles of different shapes (platelets and agglomerates) and sizes (from 2 to 180μm), and hence with different sp. surface areas. The cure kinetics has been studied by differential scanning calorimetry in both non-isothermal and isothermal modes, and it has been shown that there is a systematic dependence of the cure kinetics on the BN content, the cure reaction generally being retarded by the addition of the BN particles. For filler loadings greater than about 30 vol%, the retardation of the cure, in both isothermal and non-isothermal mode, appears also to decrease as the sp. surface area decreases. For the smallest (2μm) platelets, which have a significantly higher sp. surface area (10 m2 g-1), the retardation is particularly pronounced, and this aspect is rationalized in terms of the activation energy and frequency factor of the reaction. The agglomerates, though, give the highest values of thermal conductivity, contrary to what might be expected in the light of their sp. surface areas. SEM of the fracture surfaces of the cured composites has been used to show that the interface between epoxy matrix and filler particles is better for the agglomerates. This, together with the reduced interfacial area, explains their higher thermal conductivity

Journal of Thermal Analysis and Calorimetry published new progress about Activation energy. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, SDS of cas: 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Podgorski, Maciej published the artcileThiol-Anhydride Dynamic Reversible Networks, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate), the main research area is thiol anhydride photopolymer stress relaxation dynamic network; covalent adaptable networks; dynamic composites; photopolymers; recycling; stress relaxation.

The reaction of thiols and anhydrides to form ring opened thioester/acids is shown to be highly reversible and it is accordingly employed in the fabrication of covalent adaptable networks (CANs) that possess tunable dynamic covalent chem. Maleic, succinic, and phthalic anhydride derivatives were used as bifunctional reactants in systems with varied stoichiometries, catalyst, and loadings. Dynamic characteristics such as temperature-dependent stress relaxation, direct reprocessing and recycling abilities of a range of thiol-anhydride elastomers, glasses, composites and photopolymers are discussed. Depending on the catalyst strength, 100% of externally imposed stresses were relaxed in the order of minutes to 2 h at mild temperatures (80-120°C). Pristine properties of the original materials were recovered following up to five cycles of a hot-press reprocessing technique (1 h/100°C).

Angewandte Chemie, International Edition published new progress about Activation energy. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts