Month: December 2022

Racolta, E. published the artcileComparatives technologies for dietetic candies production, Synthetic Route of 64519-82-0, the main research area is dietetic candy extrusion color adhesion isomalt.

The production of dietetic candies using isomalt as sugar substitute and some natural ingredients was carried out on a classical technol. line with small batch of 25 kg. The caramel mass obtained by replacing sugar with isomalt, was characterized from rheol., sensorial, phys. – chem. point of view. The improvement of nutritional value was made by adding natural ingredients on the classical technol. line of sugar and glucose syrup candies production by stamping the candy mass. Based on the comparative study of the mentioned parameters, it can be state that the free sugar, but with natural ingredients candies are difficult to produced using the classical technol. due to the differences between the rheol. and phys. – chem. properties of those candies compared with sugar candies. In our study, we produced the caramel mass on the same under vacuum boiling system, but the candy formation was made by casting or extrusion.

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Agriculture published new progress about Candy (dietetic). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Synthetic Route of 64519-82-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Garcia, Margarita published the artcileSequential Non-Saccharomyces and Saccharomyces cerevisiae fermentations to reduce the alcoholcontent in wine, Related Products of alcohols-buliding-blocks, the main research area is Saccharomyces Wickerhamomyces Meyerozyma Metschnikowia fermentation alc reduction wine.

Over the last decades, the average alc. content of wine has increased due to climate change and consumer preferences for particular wine styles that resulted in increased grape sugar levels at harvest. Therefore, alc. reduction is a current challenge in the winemaking industry. Among several strategies under study, the use of non-conventional yeasts in combination with Saccharomyces cerevisiae plays an important role for lowering ethanol production in wines nowadays. In the present work, 33 native non-Saccharomyces strains were assayed in sequential culture with a S. cerevisiae wine strain to determine their potential for reducing the alc. content in Malvar white wines. Four of the non-Saccharomyces strains (Wickerhamomyces anomalus 21A-5C, Meyerozyma guilliermondii CLI 1217, and two Metschnikowia pulcherrima (CLI 68 and CLI 460)) studied in sequential combination with S. cerevisiae CLI 889 were best able to produce dry wines with decreased alc. proportion in comparison with one that was inoculated only with S. cerevisiae. These sequential fermentations produced wines with between 0.8% (volume/volume) and 1.3% (volume/volume) lower ethanol concentrations in Malvar wines, showing significant differences compared with the control. In addition, these combinations provided favorable oenol. characteristics to wines such as high glycerol proportion, volatile higher alcs., and esters with fruity and sweet character.

Fermentation published new progress about Candida stellata. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Khebri, Souad published the artcilePhytochemical Profile, Antimicrobial and Antioxidant Activities of Cistus clusii Essential oil From Algeria, Quality Control of 124-76-5, the main research area is Pseudomonas Staphylococcus essential oil phytochem antimicrobial antioxidant property Algeria.

Cistus clusii essential oil has been extracted using hydrodistillation method and characterized by GC/MS. The antioxidant activity was evaluated by two different methods DPPH free radical scavenging, and β-carotene bleaching test. The antimicrobial activity was carried out using disk diffusion method against reference strains; Pseudomonas aeruginosa (ATCC 27865), Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), clin. bacterial (Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus aureus) and fungal (Candida albicans) isolates. The chem. profile of the oil showed 31 compounds This profile was dominated by the presence of monoterpene hydrocarbons (78.4%), oxygenated derivatives (18.8%) and sesquiterpene hydrocarbons as minor constituents of this essential oil (1.9%). The major constituents were Camphene (20.6%), γ-Terpinene (16.5%), Sabinene (12.8%), and Terpineol-4 (13.5%). Other compounds were found in moderately good amounts like α-Terpinene (8.9%), α-Thujene (5.9%), α-Pinene (4.2%), and α- Terpinolene (3.1%). The results of the antimicrobial activity showed that the highest activity was observed against C. albicans and it was higher than pos. control Fluconazole. Conclusion: This study indicates that Cistus clusii essential oil showed potent antioxidant and moderate antimicrobial activities which could be used to explain the use of this species in traditional medicine.

Current Bioactive Compounds published new progress about Candida albicans. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Quality Control of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jeong, Changyoon published the artcileReal-time in situ monitoring of manufacturing process and CFRP quality by relative resistance change measurement, Quality Control of 7575-23-7, the main research area is CFRP manufacturing process in situ monitoring sensor elec resistance.

In situ monitoring of resin flow, impregnation of carbon fiber fabrics, and curing during composite manufacturing are very important for determining the quality of composite parts. In conventional methods, sensors, such as optical fibers and strain gages, are bonded to or embedded in the composites for measuring the changes in mech. and chem. properties. Although they can detect resin curing behavior and impregnation of carbon fibers, they may adversely affect the manufacturing process or structural integrity of the composites. In this study, carbon fiber itself was used as a sensor that minimizes the degradation of mech. properties and increases the efficiency of monitoring the manufacturing process. The change in the elec. resistance of carbon fiber fabrics was monitored during the various manufacturing processes when the resin flowed through the carbon fiber fabric and curing progressed. The effectiveness of this monitoring method was confirmed, and it is expected to be applicable in monitoring the quality of the finished composite parts.

Polymer Testing published new progress about Cables and Wires. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Quality Control of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Brunerie, P. published the artcileBioconversion of citronellol by Botrytis cinerea, Application of 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, the main research area is must citronellol metabolism Botrytis.

Bioconversion of citronellol (I) was studied with 4 strains of B. cinerea. Using grape must, predominant transformation of I to 2,6-dimethyl-1,8-octanediol (II) and (E)-2,6-dimethyl-2-octene-1,8-diol 3 was observed In minor amounts 2,6-dimethyl-2,8-octanediol (III), 2 p-menthane-3,8-diol isomers (IV and V), (Z)-2,6-dimethyl-2-octene-1,8-diol, isopulegol, 2-methyl-2-hepten-6-on-1-ol, and 2-methyl-γ-butyrolactone were found. Using a small amount of grape must in a synthetic medium the bioconversion products II, III, IV, and V were absent, but addnl. 2-methyl-2-heptene-6-one, 2-methyl-2-heptene-6-ol, and citronellic acid were detected. The results obtained were strongly dependent on the strains used; 1 strain did not show any metabolic activity against I.

Applied Microbiology and Biotechnology published new progress about Botrytis cinerea. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Application of 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Han published the artcileDesign of 2,5-furandicarboxylic based polyesters degraded in different environmental conditions: Comprehensive experimental and theoretical study, Recommanded Product: 2,2′-Oxydiacetic acid, the main research area is furandicarboxylic acid polyester seawater biodegradability mol dynamic simulation; Catalytic mechanism; Degradable polyesters; Enzymatic degradation; Hydrolytic reaction; MD simulation.

Nowadays, the promotion and application of aliphatic-aromatic copolyesters, such as poly (butylene adipate-co-terephthalate) (PBAT), are growing into a general trend. Although the structures of diacids exerted substantial impacts on degradation behavior, the underlying mechanisms have rarely been studied. In this work, 2,5-Furandicarboxylic acid was combined with succinic acid (PBSF), adipic acid (PBAF) and diglycolic acid (PBDF) to prepare three kinds of copolyesters. They showed unique degradation behaviors in buffer, enzyme environment and artificial seawater. These characteristics are closely related to the structural compositions of diacids. PBAFs displayed impressive biodegradability when catalyzed by Candida antarctica lipase B (CALB), while the more hydrophilic PBDFs exhibited faster hydrolysis in both buffer and artificial seawater. PBSFs, with hydrophobic and short segments, obtained a relatively slower rate of hydrolysis and enzymic degradation The reactivity sites and hydrolytic pathway were revealed by the combination of DFT calculation and Fukui function anal. MD simulations, QM/MM optimizations and theozyme calculations showed that PBAF-CALB was prone to form a pre-reaction state, leading to the reduced energy barrier in the acylation process. This work revealed the effects of different structural features of diacids on polymer degradation and paved a way to design target biodegradable polymers in different degradation conditions.

Journal of Hazardous Materials published new progress about Biodegradability. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Recommanded Product: 2,2′-Oxydiacetic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bermejo, Jesus F. published the artcileWater-soluble carbosilane dendrimers: synthesis, biocompatibility and complexation with oligonucleotides; evaluation for medical applications, Related Products of alcohols-buliding-blocks, the main research area is carbosilane dendrimer biocompatibility oligonucleotide plasmid gene delivery.

Novel amine- or ammonium-terminated carbosilane dendrimers of type nG-[Si{OCH2(C6H3)-3,5-(OCH2CH2NMe2)2}]x, nG-[Si{O(CH2)2N(Me)(CH2)2NMe2}], and nG-[Si{(CH2)3NH2}]x or nG-[Si{OCH2(C6H3)-3,5-(OCH2CHNMe3+I-)2}]x, nG-[Si{O(CH2)2N(Me)(CH2)2NMe3+I-}]x, and nG-[Si{(CH2)3NH3+Cl-}]x have been synthesized and characterized up to the third generation by two strategies: (1) alcoholysis of Si-Cl bonds with amino alcs. and subsequent quaternization with MeI, and (2) hydrosilylation of allylamine with Si-H bonds of the dendritic systems and subsequent quaternization with HCL. Quaternized carbosilane dendrimers are soluble in water, although degradation is apparent due to hydrolysis of Si-O bonds. However, dendrimers containing Si-C bonds are water-stable. The biocompatibility of the second-generation dendrimers in primary cell cultures of peripheral blood mononuclear cells (PBMCs) and erythrocytes have been analyzed, and they show good toxicity profiles over extended periods. In addition, we describe a study on the interactions between the different carbosilane dendrimers and DNA oligodeoxynucleotides (ODNs) and plasmids along with a comparative anal. of their toxicity. They can form complexes with DNA ODNs and plasmids at biocompatible doses via electrostatic interaction. Also a preliminary transfection assay has been accomplished. These results demonstrate that the new ammonium-terminated carbosilane dendrimers are good base mols. to be considered for biomedical applications.

Chemistry – A European Journal published new progress about Biocompatibility. 2212-32-0 belongs to class alcohols-buliding-blocks, name is N2-(2-Hydroxyethyl)-N1,N1,N2-trimethyl-1,2-ethylenediamine, and the molecular formula is C7H18N2O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Thijssen, Quinten published the artcileFrom Chain Growth to Step Growth Polymerization of Photoreactive Poly-ε-Caprolactone: The Network Topology of Bioresorbable Networks as Tool in Tissue Engineering, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate), the main research area is photoreactive polycaprolactone step growth polymerization thermal mech biol property.

Control of the network topol. by selection of an appropriate crosslinking chem. is introduced as a new strategy to improve the elasticity and toughness of bioresorbable networks. The development of novel photocrosslinkable and bioresorbable oligomers is essential for the application of light-based 3D-printing techniques in the context of tissue engineering. Although light-based 3D-printing techniques are characterized by an increased resolution and manufacturing speed as compared to extrusion-based 3D-printing, their application remains limited. Via chem. modification, poly-ε-caprolactone (PCL) is functionalized with photoreactive end groups such as acrylates, alkenes, and alkynes. Based on these precursors, networks with different topologies are designed via chain growth polymerization, step growth polymerization, or a combination thereof. The influence of the network topol. and the concomitant crosslinking chem. on the thermal, mech., and biol. properties are elucidated together with their applicability in digital light processing (DLP). Photocrosslinkable PCL with an elongation at break of 736.3 ± 47% and an ultimate strength of 21.3 ± 0.8 MPa is realized, which is approx. tenfold higher compared to the current state-of-the-art. Finally, extremely elastic DLP-printed dog bones are developed which can fully retrieve their initial length upon stress relieve at an elongation of 1000%.

Advanced Functional Materials published new progress about Biocompatibility. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shaha, Rajib K. published the artcileBiocompatible liquid-crystal elastomers mimic the intervertebral disc, Quality Control of 7575-23-7, the main research area is liquid crystalline elastomer tension compression biocompatibility intervertebral disk implant; Annulus fibrosus; Biocompatibility; Biomaterial; Intervertebral disc implant; Liquid crystal elastomer; Nucleus pulposus; Porous LCE; Wettability.

The hierarchical and anisotropic mech. behavior requirement of load-bearing soft tissues limits the utility of conventional elastomeric materials as a replacement for soft-tissue materials. Liquid-crystal elastomers (LCEs) have the potential to excel in this regard owing to its unique combination of mesogenic order in an elastomeric network. In this study, the mech. behavior of the LCEs relevant to load-bearing biomedical applications was explored. LCEs with different network orientations (i.e., mesogen alignments) were investigated by fabricating the LCEs with polydomain and monodomain configurations. The polydomain and monodomain LCEs with the same degree of network crosslinking demonstrated diverse mech. behavior, ranging from highly stiff and elastic nature to high damping capacity, depending on the loading direction with respect to the network alignment. The LCEs were also capable of matching the anisotropic mech. behavior of an intervertebral disk. Addnl. studies were conducted on the in vivo biol. response of LCEs upon s.c. implantation, as well as on the effect of the exposure to an in vitro simulated physiol. environment on the mech. behavior. The LCEs mech. response was negligibly affected when exposed to biomedically relevant conditions. Furthermore, the solid and porous LCEs did not show any adverse effect on the surrounding tissues when implanted s.c. in rats. The biol. response allows for tissue ingrowth and helps illustrate their utility in implantable biol. devices. Finally, the utility of LCEs to mimic the mech. function of biol. tissue such as intervertebral disk was demonstrated by fabricating a proof of concept total disk replacement device.

Journal of the Mechanical Behavior of Biomedical Materials published new progress about Biocompatibility. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Quality Control of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vieira, Nicole S. M. published the artcileHuman cytotoxicity and octanol/water partition coefficients of fluorinated ionic liquids, Name: n-Octanol, the main research area is fluorinated ionic liquid cytotoxicity octanol water partition coefficient; 1-Octanol/water partition coefficient; Cytotoxicity; Fluorinated ionic liquids; Hydrophilic/lipophilic balance.

The use of fluorinated ionic liquids (FILs) as novel materials in biol. and pharmaceutical applications is an emerging research field. The knowledge of their cytotoxicity and that of 1-octanol/water partition coefficients are essential to assess their environmental risks, to estimate their toxicity and activity, or the hydrophilic/lipophilic balance, as well as to explore their properties as solvents in extraction processes or for successful drug design. The study of the cytotoxicity in four different human cell lines and the exptl. measurement of the partition coefficient between 1-octanol and water (Po/w), using the slow-stirring method, were carried out for several FILs. In both studies, the effect of the cation ([C2C1Im]+, [C2C1py]+, [C4C1pyr]+, [N1112(OH)]+, or [N4444]+), the cationic alkyl side-chain length ([CnC1Im]+, with n = 2, 6, 8 or 12), and the anionic fluorinated chain length/anionic fluorinated domain size ([C4F9SO3] ̅, [C8F17SO3] ̅, or [N(C4F9SO3)2] ̅) were analyzed. The results reveal that both toxicity and partition properties are mainly influenced by the size of the cationic hydrogenated alkyl side-chain and that of the anionic fluorinated domain. The intrinsic tuneability of the FILs allows for their selection according to the lipophilic or hydrophilic character of the target biol. system under consideration. The toxicity studies corroborate the biocompatible nature of some FILs tested in this work. Along, for all the FILs under study Po/w < 1.00. Accordingly, a decadic logarithm of the bioconcentration factor in fish of 0.5 would be estimated, which is below the regulatory endpoint used by regulatory agencies. Chemosphere published new progress about Biocompatibility. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Name: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts