Month: December 2022

Elmhalli, Fawzeia H. published the artcileAcaricidal effects of Corymbia citriodora oil containing para-menthane-3,8-diol against nymphs of Ixodes ricinus (Acari: Ixodidae), SDS of cas: 42822-86-6, the main research area is Corymbia oil menthane diol acaricide Ixodes.

The toxicity of para-menthane-3,8-diol (PMD), the main arthropod-repellent compound in the oil of the lemon eucalyptus, Corymbia citriodora, was evaluated against nymphs of Ixodes ricinus using five methods (A-E) of a contact toxicity bioassay. Mortality rates were estimated by recording numbers of dead nymphs at 30 min intervals during the first 5 h after the start of exposure and at longer intervals thereafter. The mortality rate increased with increasing concentration of PMD and duration of exposure with a distinct effect after 3.5 h. From the results obtained by methods A, C and E, the LC50 range was 0.035-0.037 mg PMD/cm2 and the LC95 range was 0.095-0.097 mg PMD/cm2 at 4 h of exposure; the LT50 range was 2.1-2.8 h and the LT95 range was 3.9-4.2 h at 0.1 mg PMD/cm2. To determine the duration of toxic activity of PMD, different concentrations (0.002, 0.01, 0.1 mg PMD/cm2) were tested and mortality was recorded at each concentration after 1 h; thereafter new ticks were tested. This test revealed that the lethal activity of PMD remained for 24 h but appeared absent after 48 h. Thus, PMD is toxic to nymphs of I. ricinus and may be useful for tick control.

Experimental and Applied Acarology published new progress about Acaricides. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, SDS of cas: 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kini, Girish published the artcilePassive enhancement of ammonia-water absorption by the addition of surfactants, Quality Control of 111-87-5, the main research area is ammonia water absorption surfactant.

Surface-active agents or surfactants have the potential to substantially enhance heat and mass transfer in ammonia-water absorption by reducing the surface tension of the working fluid. The enhancement is caused by interfacial turbulence at the vapor-liquid interface that results from surface tension gradients. A surfactant selection criterion is developed based on the plateau value of surface tension, critical concentration, and the critical Marangoni number required to initiate interfacial turbulence. Based on this criterion, surface-active agents, and their ideal concentrations for the enhancement of ammonia-water absorption are recommended. The preferred additives are found to be 500 PPM of 1-octanol or 2-ethyl-1-hexanol. A heat and mass transfer model is developed to predict the performance of a falling-film absorber due to the addition of surfactants at conditions representative of an absorption heat pump. The model indicates that the overall conductance of the absorber is improved by ∼30% by the addition of surfactants. The results from this work can guide intensification of various coupled heat and mass transfer processes using surfactants.

International Journal of Heat and Mass Transfer published new progress about Absorption. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Quality Control of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Tao published the artcileSulfonated Poly(arylene ether sulfone) Multi-Block Copolymers with Selectively Cross-Linked Domains for Proton Exchange Membranes, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate), the main research area is sulfonated polyarylene ether sulfone proton exchange membrane.

A facile design of sulfonated poly(arylene ether sulfone) multi-block copolymer membranes with selectively cross-linked hydrophobic domains is reported for proton exchange membranes. The cross-linkable linear multi-block copolymers are prepared via coupling telechelic hydrophilic disulfonated oligomers (BPS100) and telechelic hydrophobic oligomers (PPA0) containing cross-linkable allyl-derivatized phenolphthalein moieties. The cross-linked membranes are prepared through UV-initiated thiol-ene crosslinking reactions between allyl-functionalized hydrophobic blocks with pentaerythritol tetrakis(3-mercaptopropionate) as a cross-linker. With highly cross-linked hydrophobic blocks and flexible hydrophilic blocks, the selectively cross-linked multiblock copolymer membranes exhibit remarkably improved dimensional stability and proton conductivity compared to the cross-linked random copolymers. The cross-linked membrane with the longest hydrophilic block length shows a remarkable proton conductivity of 123 mS/cm with a suppressed volume swelling ratio of 25% at 25°C. At the highest ion exchange capacity level (2.25 meq/g) and the longest block length, the cross-linked multi-block copolymer membrane outperforms Nafion over the full relative humidity range.

ACS Applied Polymer Materials published new progress about Absorption. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Khatouri, M. published the artcileEffect of hydrophobically modified PEO polymers (PEO-dodecyl) on oil/water microemulsion properties: in vitro and in silico investigations, Synthetic Route of 111-87-5, the main research area is hydrophobically modified PEO polymer oil water microemulsion property.

Microemulsions are excellent systems for transdermal delivery of multifunctional drugs because they have the potential to improve drug absorption/permeation and handling limitations. Biocompatible polymers are used as a coating of microemulsions to avoid the interactions that can occur between the microemulsions and the skin. Thus, they protect and lubricate these transporter nanovesicles. In this paper, we studied decane/water microemulsions covered with hydrophobically modified PEO polymer (PEO-m). To reveal the effect of hydrophobically modified PEO (PEO-m) polymer on the shape, the micro-arrangement and the dynamics of the microemulsions, we used an integrated strategy combining Mol. Dynamics simulation (MD), Small-Angle Neutron Scattering experiments (SANS), and the Ornstein-Zernike integral equations with the Hypernetted Chain (HNC) closure relation. We determined the microemulsion shape in vitro using the renormalized intensities spectra from SANS experiments We discussed the micro arrangements of microemulsions, in vitro and in silico, employing the pair correlation function g(r) and the structure factor S(q), obtained from the three approaches with good agreement. Thus, we used the validated MD simulations to calculate the microemulsion’s dynamics properties that we discussed using the mean-squared displacement (MSD) and the diffusion coefficients We found that the presence of moderate quantities of PEO-m, from 4 to 12 PEO-m per microemulsion, does not influence the microemulsion shape, increases the stability of the microemulsion, and slightly decrease the dynamics. Our in vitro and in silico results suggest that polymer incorporation, which has interesting in vivo implications, has no disadvantageous effects on the microemulsion properties.

RSC Advances published new progress about Absorption. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Synthetic Route of 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Karami, Thomas K. published the artcileEyes on Lipinski′s Rule of Five: A New “”Rule of Thumb”” for Physicochemical Design Space of Ophthalmic Drugs, Formula: C8H18O, the main research area is ophthalmic drug delivery physicochem design space solubility; ocular permeability thermodn property; formulation; ocular permeability; ophthalmic drug delivery; physicochemical design space; solubility.

The study objective was to investigate mol. thermodn. properties of approved ophthalmic drugs and derive a framework outlining physicochem. design space for product development. Unlike the methodol. used to obtain mol. descriptors for assessment of drug-like properties by Lipinski′s Rule of 5 (Ro5), this work presents a retrospective approach based on in silico anal. of mol. thermodn. properties beyond Ro5 parameters (ie, free energy of distribution/partitioning in octanol/water, dynamic polar surface area, distribution coefficient, and solubility at physiol. pH) by using 145 marketed ophthalmic drugs. The study′s focus was to delineate inherent mol. parameters explicitly important for ocular permeability and absorption from topical eye drops. A comprehensive parameter distribution anal. on ophthalmic drugs′ mol. properties was performed. Frequencies in distribution analyses provided groundwork for physicochem. parameter limits of mol. thermodn. properties having impact on corneal permeability and topical ophthalmic drug delivery. These parameters included free energy of partitioning (ΔGo/w) calculated based on thermodn. free energy equation, distribution coefficient at physiol. pH (clog DpH7.4), topol. polar surface area (TPSA), and aqueous solubility (Sint, SpH7.4) with boundaries of clog DpH7.4 ≤ 4.0, TPSA ≤ 250 Å2, ΔGo/w ≤ 20 kJ/mol (4.8 kcal/mol), and solubility (Sint and SpH7.4) ≥ 1 μM, resp. The theor. free energy of partitioning model streamlined calculation of changes in the free energy of partitioning, Δ(ΔGo/w), as a measure of incremental improvements in corneal permeability for congeneric series. The above parameter limits are proposed as “”rules of thumb”” for topical ophthalmic drugs to assess risks in developability.

Journal of Ocular Pharmacology and Therapeutics published new progress about Absorption. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Marques, Carolina S. published the artcileAmbipolar pentacyclic diamides with interesting electrochemical and optoelectronic properties, COA of Formula: C4H11NO2, the main research area is pentacyclic diamide organic thin film transistor electrochem optoelectronic property.

Developing organic semiconductors for organic thin film transistors (OTFT) and optoelectronic applications is a challenge. We developed highly crystalline pentacyclic diimides (3) and (4) which showed good OTFT and OLED potential and energy gaps of 2.60 eV and 2.54 eV. They exhibited interesting photo and eletroluminescence activity. Both compounds showed good quantum yields (0.56 for (3) and 0.60 for (4)).

Chemical Communications (Cambridge, United Kingdom) published new progress about Absorption. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, COA of Formula: C4H11NO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Matta, Eliana published the artcileIsomalt-Plasticized Methylcellulose-Based Films as Carriers of Ascorbic Acid, Application of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is ascorbic acid methylcellulose film physicochem property.

In the present study, isomalt-plasticized methylcellulose-based films with and without ascorbic acid (AA) addition were developed. The aims of our research were to analyze the effect of the isomalt concentration and the drying temperature upon the physicochem. properties of films, also the stability of AA during film storage. Films prepared by 1.5% w/v methylcellulose (MC) using isomalt (0.25-1.5 w/v) showed improved properties when compared to those without isomalt. Unplasticized films exhibited higher elastic modulus and lower elongation at break than films with isomalt. The AA addition increased film elongation and decreased elastic modulus. FTIR spectra indicated that addition of AA produces structural changes in films and showed the presence of AA during storage. Two drying temperatures were tested, 37°C and 45°C. The change of drying temperature to a higher temperature significantly increased film water vapor permeability (WVP) and decreased the concentration of AA present in the films compared to those dried at a lower temperature Thus, based on the WVP and AA retention results, the selected drying temperature was 37°C. Films obtained by methylcellulose (1.5%) with 0.75% of isomalt, 0.4% of ascorbic acid, and dried at 37°C can result in a good carrier of ascorbic acid. These films can be consumed through foods such as fresh or dehydrated fruits coated.

Food and Bioprocess Technology published new progress about Absorption. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Application of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Qian, Jiasheng published the artcileOne-Step Nanoextraction and Ultrafast Microanalysis Based on Nanodroplet Formation in an Evaporating Ternary Liquid Microfilm, Name: n-Octanol, the main research area is ternary liquid microfilm nanodroplet formation nanoextn microanalysis.

Preconcentration is key for detection from an extremely low concentration solution, but requires separation steps from a large volume of samples using extracting solvents. Here, a simple approach is presented for ultrafast and sensitive microanal. from a tiny volume of aqueous solutions In this approach, liquid-liquid nanoextn. in an evaporating thin liquid film on a spinning substrate is coupled with quant. anal. in one step. The approach is exemplified using a liquid mixture comprising a target compound to be analyzed in water, mixed with extractant oil and co-solvent ethanol. With rapid evaporation of ethanol, nanodroplets of oil form spontaneously in the film. The compounds are highly concentrated by liquid evaporation and meanwhile extracted to nanodroplets. A detection limit of nanomolar to picomolar is demonstrated for fluorescent model compounds in only ≈5μL of solution with the entire process taking ≈10 s. The combination of nanoextn. and IR microscopy also enables simultaneous chem. identification. The dynamics of thin film evaporation are revealed using fast imaging. The principle behind this approach is general, providing a powerful technique for fast and sensitive chem. anal. of a vast library of compounds for environment monitoring, national security, early diagnosis, and many other applications.

Advanced Materials Technologies (Weinheim, Germany) published new progress about Absorption. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Name: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yan, Lei published the artcileBoron contributes to excessive aluminum tolerance in trifoliate orange (Poncirus trifoliata (L.) Raf.) by inhibiting cell wall deposition and promoting vacuole compartmentation, HPLC of Formula: 97-67-6, the main research area is aluminum toxicity trifoliate orange vacuole compartmentation promotion; Alleviate; Aluminum toxicity; Boron; Malate; Subcellular; Vacuole.

Boron (B) is an indispensable micronutrient for plant growth that can also alleviate aluminum (Al) toxicity. However, limited data are available on the underlying mechanisms behind this phenomenon. Here, we found that a certain range of B application could alleviate the inhibitory effects of Al toxicity on citrus. Transcriptome anal. revealed that several Al stress-responsive genes and pathways were differentially affected and enriched, such as coding for the secretion of organic acid and the distribution of Al in subcellular components after B addition Specifically, B application enhanced rhizosphere pH and induced malate exudation by expressing PtALMT4 and PtALMT9 genes occurred in Al-treated root, which ultimately reduced the absorption of Al and coincided with down-regulated the expression of PtNrat1. Moreover, B supply suppressed the pectin methyl-esterase (PME) activity and displayed a lower level of PtPME2 expression, while enhanced the PtSTAR1 expression, which is responsible for reducing cell wall (CW) Al deposition. Boron addition enhanced the PtALS1 and PtALS3 expression, accompanied by a higher proportion of vacuolar Al compartmentation during Al exposure. Collectively, the protective effects of B on root injury induced by Al is mainly by subsiding the Al uptake in the root apoplast and compartmentalizing Al into vacuole.

Journal of Hazardous Materials published new progress about Absorption. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, HPLC of Formula: 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Park, Jinyoung published the artcileSpatiotemporal vitrimerization of a thermosetting polymer using a photo-latent catalyst for transesterification, Product Details of C17H28O8S4, the main research area is thermosetting polymer transesterification photolatent catalyst.

Globally rising environmental concerns have increased the demand for recyclable polymers and efficient recycling practices. The lack of melt-processability of thermosets significantly limits their recycling because the simplest and most economical way to recycle polymers with a min. carbon footprint is repairing or re-melting them into new items. To this end, an approach to spatiotemporally converting a thermoset into a processable vitrimer is presented. This was achieved by incorporating a latent, heat-stable photo-active catalyst into an otherwise thermoset, activating network exchange reactions only after light exposure and subsequent heating. The thermoset film could be repaired and/or heat-processed by simply exposing the sample to light followed by annealing at elevated temperature and pressure, whereas the repairing/heat-processing failed in the absence of the light exposure step. This approach enables the polymer to initially behave as a thermoset at all temperatures until it requires repair or heat-processing.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about Absorption. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Product Details of C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts