Month: December 2022

Yavuz, Mustafa Selman published the artcileHighly efficient chlorinated solvent uptake by novel covalent organic networks via thiolene chemistry, Computed Properties of 7575-23-7, the main research area is covalent organic network adsorbent chlorinated solvent uptake.

In this study, an aliphatic-aromatic regular network is synthesized as a novel covalent organic networks called TEPN-1 (Thiol-ene Polymer Network) and TEPN-2 via thiol-ene chem. TEPN-1 and TEPN-2 were analyzed by FTIR, 13C-NMR, Brunauer-Emmett-Teller, thermogravimetric anal., and elemental anal. Solvent uptake capacity of TEPN-1 and TEPN-2 was employed against 26 solvents which are frequently used in chem. industry. It is found that TEPN-1 has the highest swelling adsorption ratio with chloroform and DCM (13.7 and 11.5 g.g-1, resp.), while TEPN-2 has 9.2 and 7.5 g.g-1, resp. Both TEPN-1 and TEPN-2 have very minimal water uptake (0.165 and 0.189 g.g-1, resp.). The TEPN-1 and TEPN-2 are efficient adsorbents for most of organic solvents including water-miscible organic solvents such as THF, dioxane, and pyridine.

Polymer Bulletin (Heidelberg, Germany) published new progress about Adsorbents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Computed Properties of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yap, Pei Lay published the artcileMultithiol functionalized graphene bio-sponge via photoinitiated thiol-ene click chemistry for heavy metal ions adsorption, COA of Formula: C17H28O8S4, the main research area is wastewater adsorption graphene oxide adsorbent uv irradiation functionalization thiol; heavy metal cation seawater remediation.

Heavy metals contamination in the natural waters remains an unresolved environmental challenge pressing for the development of purification technologies. This paper presents the green engineering of a new bio-sponge for heavy metals adsorption composed of alginate bio-polymeric network encapsulated with reduced graphene oxide (rGO) modified with iron oxide nanoparticles and covalently attached multithiol (pentaerythritol tetrakis-mercaptopropionate) mols. using photoinitiated thiol-ene click chem. The multithiol functionalized graphene bio-sponge (SH-Graphene bio-sponge) is designed to enhance adsorption performances of heavy metals including structural approach combined with oxygen functionalities and high d. of sulfur-containing groups (10.2 at % S, confirmed by XPS, XPS) with high binding affinity towards specific heavy metals (Cd and Pb). It was shown that the level of thiol functionalization on the graphene structure within the bio-sponge can be controlled by tuning the UV irradiation time without adjusting the concentration of the precursors. SH-functionalized graphene bio-sponge showed outstanding adsorption capacity for Pb (II): 101.01 mg/g and Cd (II): 102.99 mg/g, outperformed com. and literature reported adsorbents in highly competitive selectivity studies using co-existing heavy metal ions (Cu, Co, Pb and Cd) spiked- sea water. The multithiol modified bio-sponge also showcased an excellent stability and reusability feature with only 0.015 mg/L Pb (II) detected, conforming the strict United States Environmental Protection Agency (US EPA) maximum contaminant level (MCL) for lead, after five recurring cycles using mixed heavy metal ions solution and acidic eluent. The outcomes from this work present valuable and promising contribution towards the development of a scalable and sustainable adsorbents for efficient remediation of heavy metals from waters.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Adsorbents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, COA of Formula: C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dai, Yingjie published the artcileNew use for spent coffee ground as an adsorbent for tetracycline removal in water, HPLC of Formula: 111-87-5, the main research area is SCG adsorbent tetracycline removal water adsorption wastewater treatment; Hydrogen bond; Hydrophobic interaction; Oxygen-containing functional groups; Removal ratio; π–π interaction.

Spent coffee grounds (SCG-1 and SCG-2) were used to study the adsorption of tetracycline (TC) antibiotics and the effects of adsorption time, initial pH, amount of adsorbent and ionic strength were detected. The TC adsorption isotherm on SCG-1 was compared with SCG-2. The results showed that the removal efficiencies of TC (50 mg/L) of SCG-1 and SCG-2 were 83.1% and 97.2%, resp., shake for 2 h. The probability of adsorption is high and balances in about 20 min. The estimate of parameters got for TC from the Langmuir isotherm saturated adsorption quantity and adsorption balance constant were 64.89 mg/g, 0.0557 L/mg, resp. for SCG-1 and 123.46 mg/g, 0.4735 L/mg, resp. for SCG-2. The adsorption mechanism might be a π-π interaction that occurs in the interface by hydrogen bonding and the between the TC mol. and the SCGs. At last, we found that SCG has a high adsorption size for TC.

Chemosphere published new progress about Adsorbents. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, HPLC of Formula: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Aili published the artcileIn-situ preparation and properties of copper nanoparticles/poly(ionic liquid) composites by click chemistry within surfactant-free ionic liquid microemulsions, Category: alcohols-buliding-blocks, the main research area is copper nanoparticle polyionic liquid reduction catalyst adsorptive wastewater treatment.

Herein, we present for the first time the facile synthesis of copper nanoparticles/poly(ionic liquid) (Cu-NPs/poly-IL) composites through the in situ click method within surfactant-free ionic liquid microemulsions. The resultant Cu-NPs/poly-IL composites were further utilized for phys. adsorption and chem. catalytic reduction of methyl orange (MO) and dispersed red (DR) in water. FTIR, NMR, XRD, TGA, DSC, SEM, and UV-vis methods were used to investigate the structure and characteristics of the designed Cu-NPs/poly-IL composites. Results showed that Cu-NPs were successfully and stably introduced on poly-ILs without oxidation and that resultant composites presented enhanced thermostability and adsorption capacity for the DR. Detailed kinetic studies and thermodn. anal. of the adsorption process were carried out. Furthermore, the catalytic reduction performance of Cu-NPs/poly-IL composites for MO and DR was investigated, and results indicated that the designed composites had certain catalytic reduction effects. Therefore, the easily synthesized Cu-NPs/poly-IL composites show remarkable potentials for wastewater treatment and purification

Journal of Molecular Liquids published new progress about Adsorbents. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

LaBella, Abigail Leavitt published the artcileSignatures of optimal codon usage in metabolic genes inform budding yeast ecology, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is optimal codon metabolic gene budding yeast ecol.

Reverse ecol. is the inference of ecol. information from patterns of genomic variation. One rich, heretofore underutilized, source of ecol. relevant genomic information is codon optimality or adaptation. Bias toward codons that match the tRNA pool is robustly associated with high gene expression in diverse organisms, suggesting that codon optimization could be used in a reverse ecol. framework to identify highly expressed, ecol. relevant genes. To test this hypothesis, we examined the relationship between optimal codon usage in the classic galactose metabolism (GAL) pathway and known ecol. niches for 329 species of budding yeasts, a diverse subphylum of fungi. We find that optimal codon usage in the GAL pathway is pos. correlated with quant. growth on galactose, suggesting that GAL codon optimization reflects increased capacity to grow on galactose. Optimal codon usage in the GAL pathway is also pos. correlated with human-associated ecol. niches in yeasts of the CUG-Ser1 clade and with dairy-associated ecol. niches in the family Saccharomycetaceae. For example, optimal codon usage of GAL genes is greater than 85% of all genes in the genome of the major human pathogen Candida albicans (CUG-Ser1 clade) and greater than 75% of genes in the genome of the dairy yeast Kluyveromyces lactis (family Saccharomycetaceae). We further find a correlation between optimization in the GALactose pathway genes and several genes associated with nutrient sensing and metabolism This work suggests that codon optimization harbors information about the metabolic ecol. of microbial eukaryotes. This information may be particularly useful for studying fungal dark matter-species that have yet to be cultured in the lab or have only been identified by genomic material.

PLoS Biology published new progress about Adaptation. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application of (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Stankova, Pavla published the artcileAdaptation of mitochondrial substrate flux in a mouse model of nonalcoholic fatty liver disease, Synthetic Route of 97-67-6, the main research area is mitochondrial substrate flux nonalcoholic fatty liver disease adaptation animal; mitochondria; nonalcoholic fatty liver disease; oxidative phosphorylation; respirometry.

Maladaptation of mitochondrial oxidative flux seems to be a considerable feature of nonalcoholic fatty liver disease (NAFLD). The aim of this work was to induce NAFLD in mice fed a Western-style diet (WD) and to evaluate liver mitochondrial functions. Experiments were performed on male C57BL/6J mice fed with a control diet or a WD for 24 wk. Histol. changes in liver and adipose tissue as well as hepatic expression of fibrotic and inflammatory genes and proteins were evaluated. The mitochondrial respiration was assessed by high-resolution respirometry. Oxidative stress was evaluated by measuring lipoperoxidation, glutathione, and reactive oxygen species level. Feeding mice a WD induced adipose tissue inflammation and massive liver steatosis accompanied by mild inflammation and fibrosis. We found decreased succinate-activated mitochondrial respiration and decreased succinate dehydrogenase (SDH) activity in the mice fed a WD. The oxidative flux with other substrates was not affected. We observed increased ketogenic capacity, but no impact on the capacity for fatty acid oxidation We did not confirm the presence of oxidative stress. Mitochondria in this stage of the disease are adapted to increased substrate flux. However, inhibition of SDH can lead to the accumulation of succinate, an important signaling mol. associated with inflammation, fibrosis, and carcinogenesis.

International Journal of Molecular Sciences published new progress about Adaptation. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Synthetic Route of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Motallae, Saeed published the artcilePreparation and characterization of solid dispersions of celecoxib obtained by spray-drying ethanolic suspensions containing PVP-K30 or isomalt, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is acute pain celecoxib bioavailability dispersion suspension.

Celecoxib (CLX) is an anti-inflammatory drug that is used for acute pain treatment, but it has very low oral bioavailability owing to its poor water solubility In this study, CLX solid dispersions are prepared by spray-drying using hydrophilic carriers with the aim of improving its apparent solubility and dissolution rate. Blends with different ratios of CLX, isomalt (ISO) and PVP were prepared in ethanol, and solid dispersions were obtained using a spray dryer. The saturation solubility and dissolution kinetics in 0.25% SLS and 0.04 M Na3PO4 containing media were determined Also, SEM, DSC, XRPD, and stability studies were used to characterize the systems. Physicochem. anal. demonstrated the presence of amorphous CLX in the spray dried samples. The saturation solubility and dissolution rate of CLX from these formulations were higher than those for pure celecoxib and its phys. mixtures Amorphous CLX showed a lower dissolution rate compared to its crystalline form in 0.25% SLS medium, while this tendency was reversed under alk. conditions. The CLX:PVP:ISO 3:5:2 spray dried sample showed the highest dissolution rate in both media. Exposure of samples to high moisture (75% humidity) recrystallized some of the amorphous CLX. Thus, the results showed that the dissolution rate of CLX was enhanced in 0.25% SLS, whereas a reduction in dissolution rate was observed in 0.04 M Na3PO4.

Journal of Drug Delivery Science and Technology published new progress about Acute pain. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Saha, B. published the artcileEnhanced exudation of malate in the rhizosphere due to AtALMT1 overexpression in blackgram (Vigna mungo L.) confers increased aluminium tolerance, Synthetic Route of 97-67-6, the main research area is acidic soil aluminum toxicity blackgram citrate malate; AtALMT1 acidic soil aluminum toxicity blackgram citrate malate; Acidic soil; aluminium toxicity; blackgram; citrate; malate.

Worldwide, 50% of soil is acidic, which induces aluminum (Al) toxicity in plants, as the phyto-availability of Al3+ increases in acidic soil. Plants responds to Al3+ toxicity by exuding organic acids into the rhizosphere. The organic acid responsible for Al3+ stress response varies from species to species, which in the case of blackgram (Vigna mungo L.) is citrate. In blackgram, an Arabidopsis malate transporter, AtALMT1, was overexpressed with the motive of inducing enhanced exudation of malate. Transgenics were generated using cotyledon node explants through Agrobacterium tumefaciens-mediated transformation. The putative transgenics were initially screened by AtALMT1-specific genomic DNA PCR, followed by quant. PCR. Two independent transgenic events were identified and functionally characterized in the T3 generation. The transgenic lines, Line 1 and 2, showed better root growth, relative water content and chlorophyll content under Al3+ stress. Both lines also accounted for less oxidative damage, due to reduced accumulation of ROS mols. Photosynthetic efficiency, as measured in terms of Fv/Fm, NPQ and Y(II), increased when compared to the wild type (WT). Relative expression of genes (VmSTOP1, VmALS3, VmMATE) responsible for Al3+ stress response in blackgram showed that overexpression of a malate transporter did not have any effect on their expression. Malate exudation increased whereas citrate exudation did not show any divergence from the WT. A pot stress assay found that the transgenics showed better adaptation to acidic soil. This report demonstrates that the overexpression of a malate transporter in a non-malate exuding species improves adaptation to Al3+ toxicity in acidic soil without effecting its stress response mechanism.

Plant Biology (Berlin, Germany) published new progress about Acid soils. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Synthetic Route of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chauhan, Devendra Kumar published the artcileAluminum toxicity and aluminum stress-induced physiological tolerance responses in higher plants, Application In Synthesis of 97-67-6, the main research area is review aluminum toxicity stress plant nutrient; ABC transporters; ALMT malate; Acidic soil; MATE citrate; Nramp; aluminum toxicity; marker-assisted breeding programs; tolerance.

Aluminum (Al) precipitates in acidic soils having a pH < 5.5, in the form of conjugated organic and inorganic ions. Al-containing minerals solubilized in the soil solution cause several neg. impacts in plants when taken up along with other nutrients. Moreover, a micromolar concentration of Al present in the soil is enough to induce several irreversible toxicity symptoms such as the rapid and transient over-generation of reactive oxygen species (ROS) such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (OH), resulting in oxidative bursts. In addition, significant reductions in water and nutrient uptake occur which imposes severe stress in the plants. However, some plants have developed Al-tolerance by stimulating the secretion of organic acids like citrate, malate, and oxalate, from plant roots. Genes responsible for encoding such organic acids, play a critical role in Al tolerance. Several transporters involved in Al resistance mechanisms are members of the Aluminum-activated Malate Transporter (ALMT), Multidrug and Toxic compound Extrusion (MATE), ATP-Binding Cassette (ABC), Natural resistance-associated macrophage protein (Nramp), and aquaporin gene families. Therefore, in the present review, the discussion of the global extension and probable cause of Al in the environment and mechanisms of Al toxicity in plants are followed by detailed emphasis on tolerance mechanisms. We have also identified and categorized the important transporters that secrete organic acids and outlined their role in Al stress tolerance mechanisms in crop plants. The information provided here will be helpful for efficient exploration of the available knowledge to develop Al tolerant crop varieties. Critical Reviews in Biotechnology published new progress about Acid soils. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Application In Synthesis of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Garboui, Samira S. published the artcileRepellency of MyggA Natural spray (para-menthane-3,8-diol) and RB86 (neem oil) against the tick Ixodes ricinus (Acari: Ixodidae) in the field in east-central Sweden, SDS of cas: 42822-86-6, the main research area is MyggA para menthanediol RB86 azadirachtin neem oil tick repellent.

In the field in south-central Sweden, we tested by randomized, standardized methodol. the potential anti-tick repellent activity of 2 concentrations of MyggA Natural spray (containing PMD) (4.2 and 3.2 g/m2) and one of RB86 (with 70% neem oil containing azadirachtin)(3 g/m2) to host seeking nymphs of Ixodes ricinus. Each substance was applied sep. to 1 m2 cotton flannel cloths. Nymphal ticks on the cloths, pulled over the vegetation, were recorded at 10-m stops. Nymphal numbers recorded differed significantly between treated cloths [4.2 or 3.2 g MyggA Natural spray/m2 and 3 g RB86/m2] and the untreated control (df = 3, χ2 = 112.74). Nymphal numbers also differed significantly among collectors (df = 3, χ2 = 15.80). Repellency of treated cloths, i.e., 4.2 or 3.2 g MyggA Natural spray/m2 and 3 g RB 86/m2 declined from day 0 (i.e. the day of impregnation) to day 3 after impregnation from 77 to 24%, 58 to 16%, and 47 to 0.5%, resp. This study suggests that all 3 treatments have significant repellent activities against I. ricinus nymphs.

Experimental and Applied Acarology published new progress about Acaricides. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, SDS of cas: 42822-86-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts