Month: December 2022

Yeh, Ping-Yuan published the artcileChanges undergone by citronella-oil fractions on storage, Product Details of C10H20O2, the main research area is .

During 43-month storage in the dark at room temperature some of the distilled citronella oil fractions had completely changed. The changed citronellal fraction consisted of H2O 1, isopulegol 20, menthoglycol (?) 10, citronellic acid 12, and citronellylidenecitronellal and higher condensation products 57%. The terpene fractions and the terpene alc. fractions also changed to the oxidation, condensation, and polymerization products. A pure citronellal fraction stood for 5 years almost unchanged.

Taiwan Kexue published new progress about Alcohols. 42822-86-6 belongs to class alcohols-buliding-blocks, name is 2-(2-Hydroxypropan-2-yl)-5-methylcyclohexanol, and the molecular formula is C10H20O2, Product Details of C10H20O2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Zhirui published the artcileNetwork pharmacology-based dissection of the underlying mechanisms of dyspnoea induced by zedoary turmeric oil, Formula: C10H18O, the main research area is network pharmacol dyspnoea zedoary turmeric oil; binding affinity; dyspnoea; haemoglobin; network pharmacology; zedoary turmeric oil.

Zedoary turmeric oil (ZTO) has been widely used in clinic. However, the unpleasant induced dyspnoea inevitably impedes its clin. application. Thus, it is urgent to elucidate the mechanism underlying the ZTO-induced dyspnoea. In this study, network pharmacol. was firstly performed to search the clue of ZTO-induced dyspnoea. The key target genes of ZTO-induced dyspnoea were analyzed using GO enrichment anal. and KEGG pathway anal. GO anal. suggested that haem binding could be a key mol. function involved in ZTO-induced dyspnoea. Hence, the Hb (Hb) was focused for its oxygen-carrying capacity with haem as its critical component binding to the oxygen. UV-visible absorption spectrum indicated that the ZTO injection (ZTOI) perturbed the Soret band of Hb, suggesting an interaction between ZTO and Hb. GC-MS anal. revealed that β-elemene, germacrone, curdione and furanodiene were main components of ZTOI. Mol. docking was used to illustrate the high affinity between representative sesquiterpenes and Hb, which was finally confirmed by surface plasmon resonance, suggesting their potential roles in dyspnoea by ZTO. Following a network pharmacol.-driven strategy, our study revealed an intervened Hb-based mechanism underlying the ZTO-induced dyspnoea, providing a reference for elucidating mechanism underlying adverse drug reactions of herbal medicines in clinic.

Basic & Clinical Pharmacology & Toxicology published new progress about Affinity. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Formula: C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Paruli, Ernesto III published the artcileMolecularly imprinted polymers by thiol-yne chemistry: making imprinting even easier, Quality Control of 7575-23-7, the main research area is thiol ene microsphere molecularly imprinted polymer preparation property.

Molecularly imprinted polymers (MIPs) are synthetic materials with recognition properties comparable to those of antibodies, but with superior physico-chem. stability. Synthesized in the presence of a template, MIPs contain binding sites with high specificity and selectivity for their target. In this work, we explored the radical-mediated thiol-yne chem. as a new approach to MIPs, using propranolol as a model template and acrylic acid as a functional monomer. Thiol-yne chem. proved to be advantageous due to its oxygen tolerance and reactivity with (meth)acrylates. Thus, polymerization was possible in air with no need for previous deoxygenation, which is important for MIPs shaped by micro or nanofabrication. Moreover, the incorporation of ester-based polythiols made the MIPs hydrolyzable in basic and acidic conditions, thus potentially reducing their persistence in the environment. This, together with the possibility of using the well-established library of template-functional monomer(s) pairs based on (meth)acrylates, is expected to rapidly spread the use of the thiol-yne chem. within the imprinting community.

Polymer Chemistry published new progress about Affinity. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Quality Control of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cai, Qinhong published the artcileA cross-comparison of biosurfactants as marine oil spill dispersants: Governing factors, synergetic effects and fates, Related Products of alcohols-buliding-blocks, the main research area is biosurfactant oil spill dispersant synergetic effect biodegradation wastewater treatment; Biosurfactant-based dispersants; Exmulsins; Oil spill dispersion; Surfactins; Trehalose lipids.

Biosurfactant-based dispersants (BBDs) may be more effective, cost-efficient and environmentally friendly than dispersants currently used for oil spill response. An improved understanding of BBD performance is needed to advance their development and com. use. In this study, the ability of four BBDs, i.e. sufactins, trehalose lipids, rhamnolipids and exmulsins, alone and as various combinations to disperse Arabian light crude oil and weathered Alaska North Slope crude oil was compared to a widely used com. oil dispersant (Corexit 9500A). Surfactin and trehalose lipids, which have balanced surface activity/emulsification ability, showed dispersion efficacy comparable to Corexit 9500A. Rhamnolipids (primarily a surface-active agent) and exmulsins (primarily an emulsifier) when used alone had significantly lower efficacy. However, blends of these surfactants had excellent dispersion performance because of synergistic effects. Balanced surface activity and emulsification ability may be key to formulate effective BBDs. Of the BBDs evaluated, surfactins with an effective dispersant-to-oil ratio as low as 1:62.3 and trehalose lipids with high oil affinity, biodegradation rate, and low toxicity characteristics show the most promise for com. development.

Journal of Hazardous Materials published new progress about Affinity. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kolacinska, Kamila published the artcileApplication of new covalently-bound diglycolamide sorbent in sequential injection analysis flow system for sample pretreatment in ICP-MS determination of 239Pu at ppt level, Synthetic Route of 110-99-6, the main research area is diglycolamide sorbent sequential injection analysis pretreatment plutonium ICP MS; Diglycolamide; ICP-MS; Nuclear reactor coolant; Plutonium; Sequential injection analysis; Solid-phase extraction.

Diglycolamide ligands are widely applied in the anal. of radionuclides, especially lanthanides and actinides. They are used in liquid-liquid extraction procedures or in solid-phase extraction sorbents where they are adsorbed on the surface of hydrophobic polymers. The main objective of this study was to synthesize the N,N,N’N’-tetrahexyl diglycolamide with one vinyl terminating group (vTHDGA) for further covalent immobilization on the polystyrene-divinylbenzene polymeric support. The obtained complexing resin (THDGA) was employed for the mechanized sample pretreatment in the Sequential Injection Anal. – Lab-on-Valve (SIA-LOV) flow system for the determination of 239Pu using ICP-MS detection. The anal. procedure was optimized in terms of selectivity towards several other radionuclides and elements forming potentially isobaric interferences in mass spectrometry. For 100 mL volume of sample to be analyzed, the method detection limit (MDL) was 96 mBq L-1 (42 pg L-1). The developed method was employed for the determination of 239Pu in real samples of a nuclear reactor coolant and spent fuel pool water from a nuclear reactor.

Talanta published new progress about Affinity. 110-99-6 belongs to class alcohols-buliding-blocks, name is 2,2′-Oxydiacetic acid, and the molecular formula is C4H6O5, Synthetic Route of 110-99-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Serna, Sonia published the artcileConstruction of N-Glycan Microarrays by Using Modular Synthesis and On-Chip Nanoscale Enzymatic Glycosylation, Product Details of C13H19NO3, the main research area is construction glycan microarray modular synthesis chip nanoscale enzymic glycosylation.

An effective chemoenzymic strategy is reported that has allowed the construction, for the first time, of a focused microarray of synthetic N-glycans. Based on modular approaches, a variety of N-glycan core structures have been chem. synthesized and covalently immobilized on a glass surface. The printed structures were then enzymically diversified by the action of three different glycosyltransferases in nanodroplets placed on top of individual spots of the microarray by a printing robot. Conversion was followed by lectin binding specific for the terminal sugars. This enzymic extension of surface-bound ligands in nanodroplets reduces the amount of precious glycosyltransferases needed by seven orders of magnitude relative to reactions carried out in the solution phase. Moreover, only those ligands that have been shown to be substrates to a specific glycosyltransferase can be individually chosen for elongation on the array. The methodol. described here, combining focused modular synthesis and nanoscale on-chip enzymic elongation, could open the way for the much needed rapid construction of large synthetic glycan arrays.

Chemistry – A European Journal published new progress about Affinity. 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Product Details of C13H19NO3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, Weihong published the artcileMajor constituents of cannabis vape oil liquid, vapor and aerosol in California vape oil cartridge samples, Computed Properties of 124-76-5, the main research area is cannabis vape oil liquid vapor aerosol major constituent GCMS; EVALI (e-cigarette or vaping product use-associated lung injury); GC-MS; aerosol; delta-9 tetrahydrocannabinol; nontarget; toxin; vape oil; vapor.

During the E-cigarette or Vaping product use Associated Lung Injury (EVALI) outbreak of August 2019 to Feb. 2020, the California Department of Public Health, Food and Drug Laboratory Branch received numerous cannabis vape oil cartridge investigation samples from throughout the state. Many of these products were directly linked to patients; others were collected as part of investigations. We determined the major ingredients and additives in twelve unused cannabis vape oil cartridge samples obtained before (n = 2) and during the EVALI outbreak (n = 10) in California from Sept. 2018 to Dec. 2019. We tested for major constituents in vape oil liquid, vape oil vapor, and vape oil aerosol phases. A nontargeted Gas Chromatog. Mass Spectrometry direct injection screening method was developed for vape oils, a headspace heating module used for vape oil vapors and a solid-phase microextraction (SPME) vaping rig for aerosols generated by vaping. We have identified more than 100 terpenes and natural extracts, 19 cannabinoids, and other potential toxic additives such as Vitamin E Acetate, Polyethylene Glycols, and Medium Chain Triglycerides. We determined more terpenes and minor cannabinoids can be produced via vaporizing and aerosolizing the vape oil. Delta9-THC and potential toxic additives were found at lower levels in the vapor and aerosol than in the vape liquid

Frontiers in Chemistry (Lausanne, Switzerland) published new progress about Aerosols. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Computed Properties of 124-76-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Azeem, Hafiz Abdul published the artcileExtending the scope of dispersive liquid-liquid microextraction for trace analysis of 3-methyl-1,2,3-butanetricarboxylic acid in atmospheric aerosols leading to the discovery of iron(III) complexes, Recommanded Product: n-Octanol, the main research area is dispersive liquid microextraction trace analysis methylbutanetricarboxylic acid; atm aerosol iron complex monoterpene complexation vegetation; Biogenic secondary organic aerosol; Dispersive liquid–liquid microextraction; MBTCA; Metal complexes; Trace analysis.

3-Methyl-1,2,3-butanetricarboxylic acid (MBTCA) is a secondary organic aerosol and can be used as a unique emission marker of biogenic emissions of monoterpenes. Seasonal variations and differences in vegetation cover around the world may lead to low atm. MBTCA concentrations, in many cases too low to be measured. Hence, an important tool to quantify the contribution of terrestrial vegetation to the loading of secondary organic aerosol may be compromised. To meet this challenge, a dispersive liquid-liquid microextraction (DLLME) method, known for the extraction of hydrophobic compounds, was extended to the extraction of polar organic compounds like MBTCA without compromising the efficiency of the method. The extraction solvent was fine-tuned using tri-n-octyl phosphine oxide as additive. A multivariate exptl. design was applied for deeper understanding of significant variables and interactions between them. The optimum extraction conditions included 1-octanol with 15% tri-n-octyl phosphine oxide (weight/weight) as extraction solvent, MeOH as dispersive solvent, 25% NaCl dissolved in 5 mL sample (weight/weight) acidified to pH 2 using HNO3, and extraction time of 15 min. A limit of detection of 0.12 pg/m3 in air was achieved. Also, unique complexation behavior of MBTCA with Fe(III) was found when analyzed with ultra-HPLC coupled with electrospray ionization-quadrupole time-of-flight mass spectrometry (UHPLC-ESI-QToF). A comprehensive overview of this complexation behavior of MBTCA was examined with systematically designed experiments This newly discovered behavior of MBTCA will be of interest for further research on organometallic photooxidation chem. of atm. aerosols.

Analytical and Bioanalytical Chemistry published new progress about Aerosols. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ugbabe, Grace E. published the artcileChemo-microscopy of the leaves and GC-MS analyses of oils from different parts of Lantana camara linn grown in Nigeria, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is Lantana camara linn chemomicroscopy GCMS analyses.

Chemo-microscopic anal. of Lantana camara Linn revealed the presence of lignin, starch, cellulose, oxalate crystals, tannin, oils, proteins and absence of mucilage in the leaves while the flowers showed the presence of all tested metabolites except mucilage and lignin. The GC-MS anal. of volatile oils of different parts (leaves, flowers, fruits) obtained by hydro-distillation was carried out. The total components detected in the oil of the leaf were 48, the flower oil had 49, and the fruit oil had 14 compounds, the major components common in the parts studied were: eucalyptol, beta-caryophyllene and alpha-caryophyllene. The components with the highest percentage compositions in the leaves were: gamma-terpinene (10.24%), eucalyptol (9.36%), alpha-pinene (5.82%), beta-caryophyllene (5.13%). In the flowers the components that had the highest composition were: eucalyptol (7.65%), trans-nerolidol (7.17%), beta-caryophyllene (6.95%), sabinene (6.29%), 14-hexadecatetraenyl acetate (5.82%), alpha-caryophyllene (5.81%) and in the fruits the components that had the highest composition were: phytol (23.04%), octadec-9-enoic acid (15.50%), beta-caryophyllene (13.57%), sabinene (9.66%), nhexadecanoic acid (9.51%), alpha-caryophyllene (6.97%) and trans-nerolidol (6.93%). The chemo-microscopic and GC-MS characterization of Lantana camara can be used for identification and quality control of the L. camara as a crude drug. Volatile oil constituents found in the different parts of the plant find applications in flavorings, fragrances or perfumery, cough suppressant, manufacture of cosmetic products, manufacture of detergents, soaps, emulsifying agent, manufacture of synthetic vitamin E and vitamin K1 as well as antiinflammatory, anti-bacterial and anti-fungal agents and manufacture of aerosol product and insecticides.

European Journal of Biomedical and Pharmaceutical Sciences published new progress about Aerosols. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Yi-Fan published the artcileTreatment of particle/gas partitioning using level III fugacity models in a six-compartment system, HPLC of Formula: 111-87-5, the main research area is particle gas partitioning fugacity model six compartment system; Equilibrium; Fugacity model; Particle/gas partition; SVOCs; Steady state.

In this paper, two level III fugacity models are developed and applied using an environmental system containing six compartments, including air, aerosols, soil, water, suspended particulate matters (SPMs), and sediments, as a “”unit world””. The first model, assumes equilibrium between air and aerosols and between water and SPMs. These assumptions lead to a four-fugacity model. The second model removes these two assumptions leading to a six-fugacity model. The two models, compared using four PBDE congeners, BDE-28, -99, -153, and -209, with a steady flux of gaseous congeners entering the air, lead to the following conclusions. 1. When the octanol-air partition coefficient (KOA) is less than 1011.4, the two models produce similar results; when KOA > 1011.4, and especially when KOA > 1012.5, the model results diverge significantly. 2. Chems. are in an imposed equilibrium in the four-fugacity model, but in a steady state and not necessary an equilibrium in the six-fugacity model, between air and aerosols. 3. The results from the six-fugacity model indicate an internally consistent system with chems. in steady state in all six compartments, whereas the four-fugacity model presents an internally inconsistent system where chems. are in equilibrium but not a steady state between air and aerosols. 4. Chems. are mass balanced in air and aerosols predicted by the six-fugacity model but not by the four-fugacity model. If the mass balance in air and aerosols is achieved in the four-fugacity model, the condition of equilibrium between air and aerosols will be no longer valid.

Chemosphere published new progress about Aerosols. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, HPLC of Formula: 111-87-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts