Month: December 2022

Vorobyova, Viktoria published the artcileApricot cake extract as corrosion inhibitor of steel: chemical composition and anti-corrosion properties, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is steel apricot cake extract corrosion inhibitor anticorrosion electrochem property.

The protection performance of self-assembled layers (SALs) formed by apricot cake extract (ACE) on the surface of steel has been studied. Characterization of the apricot cake extract was carried out using the gas chromatog.-mass spectrometry anal. The anti-corrosion effect of the self-assembled layers was determined by weight loss experiments, SEM and electrochem. methods. It was revealed that the protection ability of the SALs is determined by the time of film formation on the steel surface. The maximal corrosion inhibition efficiency (about 93%) was obtained after 48 h process of film formation in the vapor phase of the apricot cake extract The results of the polarization test revealed that the ACE acted as a mixed type inhibitor and retarded both anodic and cathodic reactions rates. The results of the electrochem. anal. revealed that the ACE modified steel showed better corrosion protection in conditions of periodic condensation of moisture.

Chemistry Journal of Moldova published new progress about Apricot. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Recommanded Product: rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Vorobyova, Viktoria published the artcileInhibition of mild steel corrosion in sodium chloride solution by apricot waste extract obtained from different solvent systems, Related Products of alcohols-buliding-blocks, the main research area is mild steel apricot waste corrosion morphol.

Purpose: This paper aims to investigate influence of extraction solvent on the efficacy of apricot pomace extract (APE) as a sustainable corrosion inhibitor for mild steel in sodium chloride solution Design/methodol./approach: The chem. profiles of the extracts were analyzed using gas chromatog.-mass spectrometry. Total phenolic, total flavonoid content and antioxidant properties of the extracts were determined Besides, gravimetric, potentiodynamic polarization and at. force microscopy were used to study the corrosion inhibition. The effect of immersion period on inhibition efficiency was evaluated. The reaction mechanism of the inhibitor was also discussed. Findings: Corrosion inhibition decreasing is in the following order: solution of 2-propanol/ethanol apricot pomace (E/PAPE) extract > ethanol (EAPE) > 2-propanol (PAPE). The gravimetric, polarization measurements and surface anal. revealed that the growth of inhibitory properties is prolonged, and corrosion rate reduction after 40-48 h of exposure was studied. Practical implications: APEs play an important role in the corrosion inhibition of mild steel in sodium chloride solution Moreover, its application is potentially possible in industries. Social implications: The results contribute to the integrated valorization of food waste. Originality/value: The different compositions of the conversion/oxidation products of organic substances in solution were studied. The formation of polymerized flavanol-aldehyde adducts and oxidized quinone compounds or tautomers structures because of extract transformation in water causes main corrosion reduction in 40-48 h.

Pigment & Resin Technology published new progress about Apricot. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Park, Sang-Seo published the artcileExercise attenuates maternal separation-induced mood disorder-like behaviors by enhancing mitochondrial functions and neuroplasticity in the dorsal raphe, Formula: C4H6O5, the main research area is biomarker exercise animal behavior maternal separation neuroplasticity mood disorder; caspase Bax dorsal raphe mitochondrial dysfunction mood disorder; Apoptosis; Dorsal raphe; Exercise; Maternal separation; Mitochondria; Mood disorder.

Loss of the mother-infant relationship during early childhood affects infant development and is known to increase the infant’s vulnerability to neuropsychiatric disorders throughout life. Serotonin deficits and mitochondrial dysfunction in the dorsal raphe may underlie mood disorders such as anxiety and depression. Exercise is known to have a pos. effect on brain function. In this study, we investigated the effect of exercise on mitochondrial function, apoptosis, and serotonin levels in the dorsal raphe as well as behavioral changes in cases of maternal separation Exposure to the stress of maternal separation resulted in mitochondrial dysfunction in the dorsal raphe, including impaired Ca2+ homeostasis, an increase in reactive oxygen species such as H2O2, and a decrease in the O2 respiration rate. Exposure to maternal separation stress also decreased tryptophan hydroxylase and 5-hydroxytryptamine pos. cells and increased apoptosis, anxiety, and depression. The impairments in mitochondrial function, apoptosis, and serotonin in the dorsal raphe, as well as anxiety and depression, were all improved by exercise. Exercise might alter mitochondrial function, serotonin levels, and the rate of apoptosis in the dorsal raphe. Therefore, exercise might be an important non-pharmacol. intervention for the prevention and treatment of the adverse effects of maternal separation

Behavioural Brain Research published new progress about Anxiety. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Formula: C4H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rossi, Marco published the artcileSeparation of O- and C-allyl glycoside anomeric mixtures by capillary electrophoresis and high-performance liquid chromatography, Related Products of alcohols-buliding-blocks, the main research area is allyl glycoside anomer capillary electrophoresis liquid chromatog.

Rapid and reliable methods for the anal. of O- and C-allyl galactopyranosides and glucopyranosides are presented, based on capillary zone electrophoresis (CZE) and micellar electrokinetic capillary chromatog. (MEKC). In MEKC, the formation of chromophoric and charged complexes between the saccharides and borate as well as the hydrophobic interactions with micelles jointly contributed to the selective separation and sensitive detection of all the investigated anomeric couples. Some non-purified synthesis mixtures of C-allyl glycosides were successfully characterized without pre-treatment. MEKC buffer conditions for which glycosides separation was successfully achieved were then exported and applied to reverse-phase liquid chromatog. (RP-HPLC), for the quant. isolation of each allyl glycoside anomer. Identification of the obtained anomeric products was performed by electrospray mass spectrometry and 13C NMR spectroscopy. Glycoside-solvent interactions driving the selective anomeric separation were shortly addressed and discussed on the basis of sugar derivatives structural differences.

Journal of Chromatography A published new progress about Anomers. 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rauter, Marion published the artcileSynthesis of benzyl β-D-galactopyranoside by transgalactosylation using a β-galactosidase produced by the over expression of the Kluyveromyces lactis LAC4 gene in Arxula adeninivorans, Related Products of alcohols-buliding-blocks, the main research area is benzyl beta galactopyranoside transgalactosylation galactosidase Kluyveromyces LAC4 Arxula.

The LAC4 gene of Kluyveromyces lactis encoding for β-galactosidase was overexpressed in the yeast Arxula adeninivorans to produce the enzyme, which can be used for the synthesis of β-D-galactosides. These compounds play a major role as precursors for the synthesis of glycolipids and glycoproteins in medicine or for the production of tensides. The Xplor2 transformation/expression platform was used because it enabled stable integration of the gene in the Arxula genome and the production of high levels of the enzyme. The recombinant β-galactosidase, fused with C-terminal His-tag region (Lac4-6hp), was purified by precipitation with ammonium sulfate and FPLC using hydroxylapatite. The enzyme exhibited optimal activity at 37 to 40°, pH 6.5 in 50 mM sodium acetate buffer. Activity was measured by the formation of p-nitrophenol at 405 nm from the hydrolyzed chromogenic substrate, p-nitrophenyl-β-D-gal. Biochem. characterization included the calculation of Km and apparent kcat values of the enzyme. The formation of benzyl β-D-gal by 0.1 U enzyme from A. adeninivorans with transgalactosylation was six times higher than that for the prokaryotic enzyme from E. coli. Moreover, the partially purified enzyme was used for the selective hydrolysis of allyl β-D-gal in a mixture of allyl β- and allyl α-D-gal, with 4 g l-1 being hydrolyzed within one day by 1 U ml-1. Thus, the recombinant β-galactosidase produced in A. adeninivorans is of potential interest for the enzymic synthesis of benzyl β-D-gal and other galactosides as well as the selective hydrolysis of anomeric mixtures and could be used to replace difficult chem. procedures.

Journal of Molecular Catalysis B: Enzymatic published new progress about Anomers. 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hui, Heping published the artcileStructural characterization, antioxidant and antibacterial activities of two heteropolysaccharides purified from the bulbs of Lilium davidii var. unicolor Cotton, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Lilium bulb heteropolysaccharide antioxidant antibacterial; Antioxidant and antibacterial activity; Heteropolysaccharides; Lilium davidii var. unicolor Cotton; Structural characterization.

Two heteropolysaccharides, BHP-1 and BHP-2, were separated and purified from the edible bulbs of Lilium davidii var. unicolor Cotton by anion-exchange and gel-permeation chromatog. The primary structural characteristics of BHP-1 and BHP-2 were investigated by Congo red test, X-ray diffractometry (XRD) anal., IR, GC and NMR. The results showed that the weight-average mol. weight (MW) and number-average mol. weight (Mn) of BHP-1 and BHP-2 were nearly 1.93 × 105 g/moL, 8.86 × 104 g/moL and 3.52 × 104 g/moL, 2.95 × 104 g/moL, resp. Glucose and mannose comprised BHP-1 in a relative molar ratio of 5.9:2.0, and BHP-2 was consisted of glucose, galactose, mannose and arabinose with approx. molar ratios of 8.3:1.5:1.0:1.1. Their backbone mainly contained α-(1 → 4)-linked D-glucopyranosyl. In addition, the C-6 of the glucose and C-2 of mannose residue of BHP-1 and BHP-2 were substituted. The two polysaccharides were semi-crystalline substance with multi-branching structure and triple helix conformation. Bioassays showed that BHP-1 and BHP-2 had effective antioxidant activities evaluated by DPPH, scavenging superoxide radical and OH radical in a dose-dependent manner. The two heteropolysaccharides also displayed distinct and selective antibacterial activity against B. cereus, P. putida, M. luteus and K. pneumonia with inhibition zones of 13 mm, 16 mm, 17 mm, 23 mm and 12 mm, 17 mm, 19 mm, 20 mm, resp. These findings provided a reference for potential applications of the polysaccharides from L. davidii as natural antioxidants and antibacterial agents in food and pharmaceuticals.

International Journal of Biological Macromolecules published new progress about Anomers. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kuerban, Mireadili published the artcileTargeting low-phytate soybean genotypes without compromising desirable phosphorus-acquisition traits, Recommanded Product: (S)-2-hydroxysuccinic acid, the main research area is phytate phosphorus acquisition soybean genotype; carboxylates; phosphorus-acquisition efficiency; phytate; root morphology; soybean germplasm.

Phytate-phosphorus (P) in food and feed is not efficiently utilized by humans and nonruminant livestock, potentially contributing to high losses of P to the environment. Crops with high P-acquisition efficiency can access soil P effectively. It remains elusive whether crop genotypes with high P-acquisition efficiency can also have low seed phytate concentrations A core collection of 256 soybean [Glycine max (L.) Merr.] genotypes from China with diverse genetic background were grown in the same environment and seeds were sampled to screen for seed phytate-P concentration Some of these genotypes were also grown in a low-P soil in the glasshouse to measure root morphol. and physiol. traits related to P acquisition. Large genotypic variation was found in seed phytate-P concentration (0.69-5.49 mg P g-1 dry weight), total root length, root surface area, rhizosheath carboxylates, and acid phosphatase activity in rhizosheath soil. Geog., seed phytate-P concentration was the highest for the genotypes from Hainan Province, whereas it was the lowest for the genotypes from Inner Mongolia. Seed phytate-P concentration showed no correlation with any desirable root traits associated with enhanced P acquisition. Two genotypes (Siliyuan and Diliuhuangdou-2) with both low phytate concentrations and highly desirable P-acquisition traits were identified. This is the first study to show that some soybean genotypes have extremely low seed phytate concentrations, combined with important root traits for efficient P acquisition, offering material for breeding genotypes with low seed phytate-P concentrations

Frontiers in Genetics published new progress about Anatomy. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Recommanded Product: (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Roman-Carrasco, Patricia published the artcileOnly α-Gal bound to lipids, but not to proteins, is transported across enterocytes as an IgE-reactive molecule that can induce effector cell activation, Computed Properties of 59-23-4, the main research area is galactose protein lipid intestinal epithelial cell allergenic activity; chylomicron; delayed allergic reaction; glycolipid; glycoprotein; red meat allergy; α-Gal.

To better understand the delayed onset of allergic symptoms and investigate whether protein-bound or lipid-bound α-Gal causes these symptoms, we analyzed the capacity of α-Gal conjugated proteins and lipids to cross a monolayer of intestinal cells. Extracts of proteins and lipids from beef were prepared, subjected to in vitro digestions, and added to Caco-2 cells grown on permeable supports. The presence of α-Gal in the basolateral medium was investigated by immunoblotting, thin-layer chromatog. with immunostaining and ELISA, and its allergenic activity was analyzed in a basophil activation test. After addition of beef proteins to the apical side of Caco-2 cells, α-Gal containing peptides were not detected in the basolateral medium. Those peptides that crossed the Caco-2 monolayer did not activate basophils from an α-Gal allergic patient. Instead, when Caco-2 cells were incubated with lipids extracted from beef, α-Gal was detected in the basolateral medium. Furthermore, these α-Gal lipids were able to activate the basophils of an α-Gal allergic patient in a dose-dependent manner. Only α-Gal bound to lipids, but not to proteins, is able to cross the intestinal monolayer and trigger an allergic reaction. This suggests that the slower digestion and absorption of lipids might be responsible for the unusual delayed allergic reactions in α-Gal allergic patients and identifies glycolipids as potential allergenic mols.

Allergy (Oxford, United Kingdom) published new progress about Allergy. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Computed Properties of 59-23-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Balmaseda, Aitor published the artcileImpact of changes in wine composition produced by non-Saccharomyces on malolactic fermentation, Synthetic Route of 97-67-6, the main research area is Oenococcus Torulaspora Saccharomyces wine malolactic fermentation; Malolactic fermentation; Non-Saccharomyces; Oenococcus oeni; Wine.

Non-Saccharomyces yeasts have increasingly been used in vinification recently. This is particularly true of Torulaspora delbrueckii and Metschnikowia pulcherrima, which are inoculated before S. cerevisiae, to complete a sequential alc. fermentation This paper aims to study the effects of these two non-Saccharomyces yeasts on malolactic fermentation (MLF) carried out by two strains of Oenococcus oeni, under cellar conditions. Oenol. parameters, and volatile and phenolic compounds were analyzed in wines. The wines were tasted, and the microorganisms identified. In general, non-Saccharomyces created more MLF friendly conditions, largely because of lower concentrations of SO2 and medium chain fatty acids. The most favorable results were observed in wines inoculated with T. delbrueckii, that seemed to promote the development of O. oeni and improve MLF performance.

International Journal of Food Microbiology published new progress about Alleles. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Synthetic Route of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

van Karnebeek, Clara D. M. published the artcileBi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy, Synthetic Route of 97-67-6, the main research area is brain developmental defect seizure encephalopathy malate aspartate GOT2; EC 2.6.1.1.; GOT2; aspartate aminotransferase; encephalopathy; inborn error of metabolism; malate-aspartate shuttle; mitochondriopathy; pyridoxine responsive epilepsy; redox imbalance; treatment.

Whole-exome sequencing was used to investigate the disease etiol. in four children from independent families with intellectual disability and epilepsy, revealing bi-allelic GOT2 mutations. In-depth metabolic studies in individual 1 showed low plasma serine, hypercitrullinemia, hyperlactatemia, and hyperammonemia. The epilepsy was serine and pyridoxine responsive. Zebrafish and mouse models were used to validate brain developmental and functional defects and to test therapeutic strategies. GOT2 encodes the mitochondrial glutamate oxaloacetate transaminase. GOT2 enzyme activity was deficient in fibroblasts with bi-allelic mutations. GOT2, a member of the malate-aspartate shuttle, plays an essential role in the intracellular NAD(H) redox balance. De novo serine biosynthesis was impaired in fibroblasts with GOT2 mutations and GOT2-knockout HEK293 cells. Correcting the highly oxidized cytosolic NAD-redox state by pyruvate supplementation restored serine biosynthesis in GOT2-deficient cells. Knockdown of got2a in zebrafish resulted in a brain developmental defect associated with seizure-like electroencephalog. spikes, which could be rescued by supplying pyridoxine in embryo water. Both pyridoxine and serine synergistically rescued embryonic developmental defects in zebrafish got2a morphants. Our data provide a mechanistic basis for the biochem. abnormalities in GOT2 deficiency that may also hold for other MAS defects.

American Journal of Human Genetics published new progress about Alleles. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Synthetic Route of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts