Month: November 2022

In Water and under Mild Conditions: α-Alkylation of Ketones with Alcohols by Phase-Transfer-Assisted Borrowing Hydrogen Catalysis was written by Rakers, Lena;Schaefers, Felix;Glorius, Frank. And the article was included in Chemistry – A European Journal in 2018.Related Products of 106-21-8 The following contents are mentioned in the article:

Borrowing hydrogen is a powerful and green technique that allows readily available alcs. to be used as alkylating agents and produces water as the only byproduct. Nevertheless, harsh conditions such as high temperatures and organic solvents are usually required. Herein, we present a strategy to perform the α-alkylation of ketones in aqueous media at mild temperatures by combining borrowing hydrogen with phase-transfer catalysis. A broad scope of Me ketones was functionalized with alkyl and benzyl alcs. in moderate to good yields at 40 °C.The protocol was also highly effective at large scale and room temperature This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Related Products of 106-21-8).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 106-21-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A Bioisosteric and Scaffold Hopping Approach for the Design and Synthesis of Double Ring Replacement Analogues of 4-Aryl-4H-Chromenes and in silico Tubulin Inhibitor Studies was written by Kottha, Thirumalaswamy S.;Gnanasambandam, Vasuki. And the article was included in ChemistrySelect in 2018.Related Products of 65-22-5 The following contents are mentioned in the article:

An eco-friendly reaction protocol was developed for the synthesis of heterocyclic hybrid scaffolds through bioisosteric replacement and scaffold hopping approach. The isosteric analogs of salicylaldehyde were designed, identified/synthesized and employed in a three component reaction to afford bioisosteric analogs of 4-aryl-4H-chromenes. Thus central core swapping of benzene-pyridine/pyrazole ring on 4-aryl-4H-chromenes was achieved under simple one-pot reaction conditions and easy work-up. Docking studies show that almost all the compounds possess good binding affinities at the colchicine binding site of tubulin. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Related Products of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Surprisingly selective sulfate extraction by a simple monofunctional di(imino)guanidinium micelle-forming anion receptor was written by Williams, Neil J.;Seipp, Charles A.;Garrabrant, Kathleen A.;Custelcean, Radu;Holguin, Erick;Keum, Jong K.;Ellis, Ross J.;Moyer, Bruce A.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2018.Reference of 106-21-8 The following contents are mentioned in the article:

The authors report a novel di(imino)guanidinium anion extractant with unparalleled selectivity for sulfate in a liquid-liquid separation system. In addition to a 4.4 order-of-magnitude enhancement in affinity compared to a standard benchmark, the alkylated di(imino)guanidinium receptor is economically synthesized and features good compatibility with application-relevant aliphatic solvents. Small-angle x-ray scattering results reveal the formation of reverse-micelles, which together with the significant organic-phase water content challenge traditional notions of selectivity in extraction of superhydrophilic anions. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Reference of 106-21-8).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Reference of 106-21-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kinetics of DNA looping by Anabaena sensory rhodopsin transducer (ASRT) by using DNA cyclization assay was written by Lee, Jae Jin;Kim, Sung Hyun;Lee, Keon Ah;Chuon, Kimleng;Jung, Kwang-Hwan;Kim, Doseok. And the article was included in Scientific Reports in 2021.Reference of 367-93-1 The following contents are mentioned in the article:

DNA cyclization assay together with single-mol. FRET was employed to monitor protein-mediated bending of a short dsDNA (∼ 100 bp). This method provides a simple and easy way to monitor the structural change of DNA in real-time without necessitating prior knowledge of the mol. structures for the optimal dye-labeling. This assay was applied to study how Anabaena sensory rhodopsin transducer (ASRT) facilitates loop formation of DNA as a possible mechanism for gene regulation. The ASRT-induced DNA looping was maximized at 50 mM of Na⁺, while Mg²⁺ also played an essential role in the loop formation. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Reference of 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Reference of 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Solubility of crystalline β-diols in water was written by Putnina, A.. And the article was included in Latvijas PSR Zinatnu Akademijas Vestis, Kimijas Serija in 1990.Name: 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

Solubilities (weight per cent) of crystalline β-diols determined by refractometry at 25° are: 2-tert-butyl-1,3-propanediol 7.9; 2,2-diethyl-1,3-propanediol 4.68; 1-(3-bromophenyl)-2,2-dimethyl-1,3-propanediol 0.20; 1,3-decanediol 0.19; 1,3-dodecanediol 0.11; 2-ethyl-2-butyl-1,3-propanediol 1.4 weight%. Values determined by gas chromatog. are: 3-phenyl-2,2-dimethyl-1,3-propanediol 0.89; 2,2-dipropyl-1,3-propanediol 0.77; 2,2,5-trimethyl-1,3-hexanediol 0.58; 1-touyl-1-phenyl-1,3-propanediol 0.21; 2,2-diisobutyl-1,3-propanediol 0.056 weight%. An empirical equation for calculating β-diol solubility is proposed. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Name: 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Transition metal complexes with thiosemicarbazide-based ligands. Part 60. Reactions of copper(II) bromide with pyridoxal S-methylisothiosemicarbazone (PLITSC). Crystal structure of [Cu(PLITSC-H)H₂O]Br·H₂O was written by Leovac, Vukadin M.;Vojinovic-Jesic, Ljiljana S.;Ivkovic, Sonja A.;Rodic, Marko V.;Jovanovic, Ljiljana S.;Hollo, Berta;Szecsenyi, Katalin Meszaros. And the article was included in Journal of the Serbian Chemical Society in 2014.COA of Formula: C8H10ClNO3 The following contents are mentioned in the article:

The synthesis and structural characterization of a square-planar copper(II) complex with pyridoxal S-methylisothiosemicarbazone (PLITSC) of the formula [Cu(PLITSC-H)H₂O]Br·H₂O (1) as the first Cu(II) complex with a monoanionic form of this ligand were described. Complex 1 together with two previously synthesized complexes [Cu(PLITSC)Br₂] (2) and [Cu(PLITSC)Br(MeOH)]Br (3) were characterized by elemental anal., IR and electronic spectroscopy and by the methods of thermal anal., conductometry and magnetic susceptibility. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5COA of Formula: C8H10ClNO3).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.COA of Formula: C8H10ClNO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Use of spiro-orthosilicates as blocked polyols/reactive diluents in high-solid PUR clear coats for car refinish applications was written by van den Berg, K. J.;van Oorschot, R.;van der Ven, L. G. J.. And the article was included in Surface Coatings International in 2006.Recommanded Product: 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

Spiro-orthosilicates, prepared from tetra-Et orthosilicate and a diol (2-butyl-2-ethyl-1,3-propanediol or 2-ethyl-1,3-hexanediol), were used as latent reactive diluent in two-pack polyurethane coatings. A fast curing and long pot life was achieved due to the latency in the can. Spiro-orthosilicates hydrolyze with moisture forming a diol and a polysiloxane. Kinetic data on hydrolysis and curing are given. The formation of polysiloxane was characterized by solid state Si NMR. The spiro-orthosilicates based films were tested as clearcoat for refinishing of automobiles. The coatings showed good stability after many car washes. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Recommanded Product: 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Use of spiro-orthosilicates as blocked polyol/reactive diluent in high solids PUR clearcoats for car refinish applications was written by van den Berg, Keimpe J.;van Oorschot, Ren;van der Ven, Leo G. J.. And the article was included in Pitture e Vernici, European Coatings in 2006.SDS of cas: 115-84-4 The following contents are mentioned in the article:

Spiro-orthosilicates, prepared from tetra-Et orthosilicate and a diol (2-butyl-2-ethyl-1,3-propanediol or 2-ethyl-1,3-hexanediol), were used as latent reactive diluent in two-pack polyurethane coatings. A fast curing and long pot life was achieved due to the latency in the can. Spiro-orthosilicates hydrolyze with moisture forming a diol and a polysiloxane. Kinetic data on hydrolysis and curing are given. The formation of polysiloxane was characterized by solid state Si NMR. The spiro-orthosilicates based films were tested as clearcoat for refinishing of automobiles. The coatings showed good stability after many car washes. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4SDS of cas: 115-84-4).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.SDS of cas: 115-84-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Reaction of Pyridoxal with Hydrophosphoryl Compounds was written by Kibardina, Lyudmila K.;Trifonov, Alexey V.;Dobrynin, Alexey B.;Pudovik, Michael A.;Burilov, Alexander R.;Sinyashin, Oleg G.. And the article was included in Heteroatom Chemistry in 2016.Related Products of 65-22-5 The following contents are mentioned in the article:

The products of carbonyl phosphonylation of pyridoxal with dialkylphosphinous acid, alkylphosphinic acid Et esters, and phosphorous acid dialkyl (or diphenyl) esters have been obtained for the first time. In some cases, the products of addition are hydrolytically unstable and stabilized by forming internal betaine structures. The reaction of pyridoxal with phosphorous acid in alc. solutions gives alkoxyfuropyridines possessing the iminium nitrogen atom. The structure and composition of the prepared compounds have been established by ³¹P and ¹H NMR spectroscopy, mass spectrometry (MALDI-TOF), and X-ray anal. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Related Products of 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Related Products of 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A general and efficient Mn-catalyzed acceptorless dehydrogenative coupling of alcohols with hydroxides into carboxylates was written by Shao, Zhihui;Wang, Yujie;Liu, Yaqian;Wang, Qian;Fu, Xiaoling;Liu, Qiang. And the article was included in Organic Chemistry Frontiers in 2018.Formula: C10H22O The following contents are mentioned in the article:

Herein, a sustainable method was developed for the synthesis of carboxylic acids RCO₂H [R = Me, Ph, 3-pyridyl, etc.] via manganese-catalyzed acceptorless dehydrogenation of alcs. generating H₂ as the sole byproduct. A wide range of carboxylic acids were synthesized with high yields and excellent functional group tolerance. The reaction proceeded selectively in the presence of a well-defined manganese pincer complex at a very low catalyst loading. Mechanistic studies including control experiments, NMR spectroscopy and X-ray crystallog. identified the resting state and key intermediates in the catalytic cycle. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Formula: C10H22O).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Formula: C10H22O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts