Month: November 2022

On January 29, 2020, Mondal, Aditesh; Reddy, Kiran P.; Bertke, Jeffery A.; Kundu, Subrata published an article.Computed Properties of 96-76-4 The title of the article was Phenol Reduces Nitrite to NO at Copper(II): Role of a Proton-Responsive Outer Coordination Sphere in Phenol Oxidation. And the article contained the following:

In the view of physiol. significance, the transition-metal-mediated routes for nitrite (NO2-) to nitric oxide (NO) conversion and phenol oxidation are of prime importance. Probing the reactivity of substituted phenols toward the nitritocopper(II) cryptate complex [mC]Cu(κ2-O2N)(ClO4) (1a), (mC = aza-oxa tripodal heteroditopic cryptand) this report illustrates NO release from nitrite at Cu(II) following a proton-coupled electron transfer (PCET) pathway. Also, a different protonated state of 1a with a proton hosted in the outer coordination sphere, [mCH]Cu(κ2-O2N)(ClO4)2 (3), also reacts with substituted phenols via primary electron transfer from the phenol. Intriguingly, the alternative mechanism operative because of the presence of a proton at the remote site in 3 facilitates an unusual anaerobic pathway for phenol nitration. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Computed Properties of 96-76-4

The Article related to phenol mediated nitrite reduction copper cryptand nitric oxide complex, crystal structure copper zinc azaoxa cryptand nitrite complex, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Computed Properties of 96-76-4

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On November 7, 2012, Manos, Manolis J.; Moushi, Eleni E.; Papaefstathiou, Giannis S.; Tasiopoulos, Anastasios J. published an article.Application In Synthesis of 2,2′-(tert-Butylazanediyl)diethanol The title of the article was New Zn2+ Metal Organic Frameworks with Unique Network Topologies from the Combination of Trimesic Acid and Amino-Alcohols. And the article contained the following:

New Zn2+-trimesate (btc3-) metal organic frameworks (MOFs) were isolated in the presence of various amino-alcs. under solvothermal conditions. Thus, the reaction of ZnCl2 with trimesic acid (H3btc) and the amino alcs. triethanolamine (teoa), 2-(hydroxymethyl)piperidine (hmpip), N-tert-butyldiethanolamine (tbdeoa), 1,4-bis(2-hydroxyethyl)piperazine (bhep), N-methyldiethanolamine (mdeoa), or 4-(2-hydroxyethyl)morpholine (hem) in a 1.6:1:5.6 molar ratio in DMF afforded compounds (teoaH)2[Zn(btc)1.33] (MOAAF-1) (MOAAF = metal organic amino-alc. framework), (NH2Me2)2(hmpipH)[Zn3(btc)3] (MOAAF-2), (NH2Me2)(tbdmaH)2[Zn3(btc)3] (MOAAF-3) (tbdma = N-tert-butyl-dimethylamine), (NH2Me2)(bhepH2)[Zn3(btc)3] (MOAAF-4), (NH2Me2)[Zn4(btc)3(mdeoa)2] (MOAAF-5), and (NH2Me2)[Zn4(btc)3(hem)2] (MOAAF-6), resp. The compounds display 3-dimensional structures with relatively large cavities (4-10 Å) and high potential solvent-accessible areas (38-68% of the unit cell volumes). A number of novel structural features are revealed in the reported MOFs, such as unprecedented dinuclear [Zn2(COO)5]-1 secondary building units (SBUs) and unique network topologies (e.g., in compounds MOAAF-2, MOAAF-3, MOAAF-5, and MOAAF-6). The amino-alcs. employed played a key role for the appearance of such novel structural features in MOAAF 1-6 since they act as bases responsible for the deprotonation of H3btc, templates, and chelating ligands. Specifically, most of the compounds synthesized are templated by protonated amino-alcs. that are involved in H bonding interactions with the frameworks, whereas in two cases (compounds MOAAF-5 and MOAAF-6) the amino-alcs. acted as chelating ligands affecting significantly the underline topol. of the MOFs. The thermal stability and photoluminescence properties of the MOFs are also discussed. This work represents the initial systematic study on the use of combination of amino-alcs. and polycarboxylate ligands for the synthesis of new MOFs, demonstrating it as a powerful synthetic strategy for the isolation of novel MOFs. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Application In Synthesis of 2,2′-(tert-Butylazanediyl)diethanol

The Article related to zinc trimesate amino mof preparation thermal stability photoluminescence, crystal structure zinc trimesate amino alc metal organic framework, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Application In Synthesis of 2,2′-(tert-Butylazanediyl)diethanol

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On August 5, 2021, Li, Na; Mao, Weimin; Gao, Yun; Wang, Ding; Song, Zhengbo; Chen, Zhongjian published an article.Application In Synthesis of 3-Hydroxyphenylacetic acid The title of the article was Liquid chromatography-mass spectrometry based metabolic characterization of pleural effusion in patients with acquired EGFR-TKI resistance. And the article contained the following:

Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) acquired resistance remains a major barrier in the clin. treatment of lung adenocarcinoma with epidermal growth factor receptor (EGFR) mutations. Despite extensive efforts, mechanism of acquired resistance has not yet been elucidated clearly. The subject of this study was to characterize the metabolic signatures relevant to acquired EGFR-TKI resistance in pleural effusion (PE), and identify potential biomarkers in PE of patients with acquired EGFR-TKI resistance. PE from EGFR-TKI untreated group (n = 30) and EGFR-TKI resistant group (n = 18) was analyzed using liquid chromatog.-mass spectrometry (LC-MS) based metabolomic. Multivariate statistical anal. revealed distinctive diff ;erences between the groups. A total of 34 significantly differential metabolites in PE were identified, among which, the acquired EGFR-TKI resistant group had higher levels of L-lysine, taurine, ornithine and citrulline, and lower levels of L-tryptophan, kynurenine, L-phenylalanine, L-leucine, N-formyl-L-methionine, 3-hydroxyphenylacetic acid and N-acetyl-D-phenylalanine in PE than that of the EGFR-TKI untreated group. These metabolites are mainly involved in six amino acid metabolic pathways. In addition, 3-hydroxyphenylacetic acid and N-acetyl-D-phenylalanine showed the highest AUC values of 0.934 and 0.929 in receiver operating characteristic anal. Through LC-MS metabolomics, our study identified potential biomarkers in PE, differentiating EGFR-TKI resistant patients from untreated patients, as well as the mechanisms underlying acquired EGFR-TKI resistance; thus, providing novel insights into acquired EGFR-TKI resistance. The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).Application In Synthesis of 3-Hydroxyphenylacetic acid

The Article related to egfr tki resistance liquid chromatog mass spectrometry pleural effusion, biomarker, egfr-tki, lung cancer, metabolomics, pleural effusion, resistance, Mammalian Pathological Biochemistry: Respiratory Diseases and other aspects.Application In Synthesis of 3-Hydroxyphenylacetic acid

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On May 7, 2021, Maurya, Mannar R.; Prakash, Ved; Avecilla, Fernando; Sankar, Muniappan published an article.Reference of 2,4-Di-tert-butylphenol The title of the article was Selective Bromination of β-Positions of Porphyrin by Self-Catalytic Behaviour of VOTPP: Facile Synthesis, Electrochemical Redox Properties and Catalytic Application. And the article contained the following:

Oxidovanadium(IV) complex of β-octabromo-meso-tetraphenylporphyrin, {[VIVO(TPPBr8)], 2} was synthesized by self-catalytic oxidative bromination of meso-tetraphenylporphyrinatooxidovanadium(IV) {[VIVO(TPP)], 1} in excellent yield under mild conditions at 25° and its structure was confirmed by single crystal x-ray study. UV-visible and 1H NMR spectra further confirmed that the meso-Ph rings are not brominated and thus emphasizes on the selectivity as well as synthetic importance of this catalytic method. In the presence of substrates e. g. phenol derivatives, 1 biomimics the vanadium bromoperoxidase (VBPO) enzyme and catalyzes the oxidative bromination of substrates in water at 25°. Remarkably, 2 also catalyzes the oxidative bromination of phenol derivatives under similar reaction conditions with very high turnover frequency (TOF) values (∼29 s-1) along with its recyclability. 2 Showed superior catalytic performance as compared to 1 because of its electron deficient nature due to electron withdrawing bromo substituents and robust saddle shaped nonplanar structure (further supported by DFT studies). The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Reference of 2,4-Di-tert-butylphenol

The Article related to vanadium phenylporphyrin bromination preparation crystal structure epr spectra electrochem, bromination phenol vanadium bromo phenylporphyrin catalyst, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Reference of 2,4-Di-tert-butylphenol

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On October 31, 2022, Zhang, Sitong; Dong, Zijian; Shi, Jia; Yang, Chengrui; Fang, Yi; Chen, Guang; Chen, Huan; Tian, Chunjie published an article.Reference of 2,4-Di-tert-butylphenol The title of the article was Enzymatic hydrolysis of corn stover lignin by laccase, lignin peroxidase, and manganese peroxidase. And the article contained the following:

Lignin of high purity and structural integrity was isolated from the enzymic residue of corn stover. Degradation of the lignin by laccase, lignin peroxidase, and manganese peroxidase was investigated. Structural changes in the lignin after degradation were characterized by SEM, nitrogen adsorption and Fourier transform IR spectroscopy, and the enzymic products were systematically analyzed by gas chromatog. mass spectrometry. The highest percentage of lignin degradation was obtained with a mixture of three enzymes (25.79%): laccase (Lac), the starting enzyme of the mixed enzyme reaction, worked with lignin peroxidase (LiP), and manganese peroxidase (MnP) to further degrade lignin. This degradation destroyed the macromol. structure of lignin, broke its key chem. bonds, and opened benzene rings, thus producing more acidic compounds This study elucidated the concept of degrading lignin from corn stover using the Lac, LiP and MnP enzymes synergistically, thus providing a theor. basis for the biodegradation of lignin. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Reference of 2,4-Di-tert-butylphenol

The Article related to lignin isolation enzymic peroxidase catalyst degradation aromatic compound, corn stover, degradation mechanism, degradation products, lignin-degrading enzyme, Cellulose, Lignin, Paper, and Other Wood Products: Lignin and other aspects.Reference of 2,4-Di-tert-butylphenol

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Nesterov, Dmytro S.; Jezierska, Julia; Nesterova, Oksana V.; Pombeiro, Armando J. L.; Ozarowski, Andrew published an article in 2014, the title of the article was An unprecedented octanuclear copper core with C3i symmetry and a paramagnetic ground state.Electric Literature of 2160-93-2 And the article contains the following content:

A complex of copper, possessing an octanuclear structure of high symmetry, was prepared by a spontaneous self-assembly reaction of Cu(BF4)2 with N-tert-butyldiethanolamine and reveals a paramagnetic ground state. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Electric Literature of 2160-93-2

The Article related to copper tertbutyldiethanolamine octanuclear complex preparation esr ferromagnetic exchange, crystal structure copper tertbutyldiethanolamine octanuclear complex, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Electric Literature of 2160-93-2

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Teng, Xingxing; Wang, Yuanyuan; Gu, Jinhua; Shi, Peiqi; Shen, Zhibin; Ye, Lianbao published an article in 2018, the title of the article was Antifungal agents: design, synthesis, antifungal activity and molecular docking of phloroglucinol derivatives.Recommanded Product: 55743-13-0 And the article contains the following content:

Pseudoaspidinol is a phloroglucinol derivative with Antifungal activity and is a major active component of Dryopteris fragrans. In our previous work, we studied the total synthesis of pseudoaspidinol belonging to a phloroglucinol derivative and investigated its antifungal activity as well as its intermediates. However, the results showed these compounds have low antifungal activity. In this study, in order to increase antifungal activities of phloroglucinol derivatives, we introduced antifungal pharmacophore allylamine into the methylphloroglucinol. Meanwhile, we remained C1-C4 acyl group in C-6 position of methylphloroglucinol using pseudoaspidinol as the lead compound to obtain novel phloroglucinol derivatives, synthesized 17 compounds, and evaluated antifungal activities on Trichophyton rubrum and Trichophyton mentagrophytes in vitro. Mol. docking verified their ability to combine the protein binding site. The results indicated that most of the compounds had strong antifungal activity, in which compound 17 were found to be the most active on Trichophyton rubrum with Min. Inhibitory Concentration (MIC) of 3.05 μg/mL and of Trichophyton mentagrophytes with MIC of 5.13 μg/mL. Docking results showed that compounds had a nice combination with the protein binding site. These researches could lay the foundation for developing antifungal agents of clin. value. The experimental process involved the reaction of 2,4,6-Trihydroxy-3-methylbenzaldehyde(cas: 55743-13-0).Recommanded Product: 55743-13-0

The Article related to trichophyton phloroglucinol derivative antifungal mol docking, allylamine, antifungal activity, molecular docking, phloroglucinol derivatives, squalene epoxidase, Pharmacology: Effects Of Antimicrobials and Parasiticides and other aspects.Recommanded Product: 55743-13-0

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On May 28, 2010, Mereacre, Valeriu; Akhtar, Muhammad Nadeem; Lan, Yanhua; Ako, Ayuk M.; Clerac, Rodolphe; Anson, Christopher E.; Powell, Annie K. published an article.Application In Synthesis of 2,2′-(tert-Butylazanediyl)diethanol The title of the article was Structures and magnetic properties of MnIII4LnIII4 aggregates with a “square-in-square” topology. And the article contained the following:

The structures and magnetic properties of a family of new octanuclear heterometallic 3d-4f complexes [MnIII4LnIII4(μ3-OH)4(μ2,η1-X)4(O2CBut)8(t-bdea)4]·solv, where X = N3-, Ln = Y (1), Eu (2), Gd (3), Tb (4), Dy (5), Ho (6); X = OCN-, Ln = Dy (7); X = NO3-, Ln = Gd (8), Tb (9), Dy (10), Ho (11), Er (12); solv = MeCN or toluene, are reported. The metal topol. in the aggregates can be described as consisting of a Ln4-square inscribed in a Mn4-square. Complexes 1-7 are prepared by the reactions of t-butyldiethanolamine (t-bdeaH2) with a preformed hexanuclear manganese pivalate complex [Mn6], the resp. lanthanide salt and either NaN3 or NaNCO, while 8-12 are obtained from the direct reaction of Mn(OAc)2, Ln(NO3)3·xH2O and t-butyldiethanolamine. The magnetic properties of all the complexes were investigated using variable temperature magnetic susceptibility and magnetization measurements. Similar magnetic behavior was observed for compounds containing the same lanthanide, indicating that changing the bridging ligand X does not have a significant effect on the magnetic behavior. The TbIII and DyIII compounds 4, 5, 7, 9 and 10 all show frequency-dependent ac susceptibilities indicative of a slow relaxation of magnetization and are therefore considered as Single-Mol. Magnets. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Application In Synthesis of 2,2′-(tert-Butylazanediyl)diethanol

The Article related to manganese lanthanide diethanolamine pivalate octanuclear preparation crystal structure, magnetic property manganese lanthanide diethanolamine pivalate octanuclear, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Application In Synthesis of 2,2′-(tert-Butylazanediyl)diethanol

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On April 24, 2017, Nesterov, Dmytro S.; Alegria, Elisabete C. B. A.; Jezierska, Julia published an article.Formula: C8H19NO2 The title of the article was A new member of CuII8 family: Synthesis, structure and magnetic properties of an octanuclear copper complex with N-tert-butyldiethanolamine. And the article contained the following:

A highly-nuclear copper complex [CuII8O(tBuDea)5(HtBuDea)Cl2][CuICl2]·2H2O (1) has been prepared in a one-pot reaction of copper chloride with N-tert-butyldiethanolamine in methanol in the open air. The structure of the complex was established by single-crystal x-ray anal. The octanuclear close-packed core of 1 belongs to the {M8(μ3-X)6(μ-X)7} mol. structure type. The ESI-MS spectroscopy confirmed the stability of the whole core in methanol solution From the ESI-MS and magnetic data the divalent oxidation state of all eight coppers in the Cu8 core is proposed. Electrochem. studies were undertaken to confirm the overall CuI/CuII composition of the complex. Thermogravimetric behavior was studied and disclosed that the complex 1 is stable until 150°. The magnetic investigations revealed a dominant antiferromagnetic coupling between copper centers within the octanuclear cation. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Formula: C8H19NO2

The Article related to copper tertbutyldiethanolamine octanuclear complex preparation crystal structure, magnetic property electrochem copper tertbutyldiethanolamine octanuclear complex, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Formula: C8H19NO2

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On May 2, 2008, Hreha, Richard J.; Vining, Benjamin John; Schueler, Robert M.; Nickerson, David published a patent.Related Products of 78-26-2 The title of the patent was Shape memory cyanate ester copolymers. And the patent contained the following:

This disclosure covers a new methodol. to produce high performance, high temperature, thermoset resins having shape memory characteristics based on cyanate ester resins. This methodol. is based on pericyclic polycyclotrimerizations by utilizing a heretofore unknown polymerization mechanism based on equilibrium controlled condensation and cyclization. A monofunctional cyanate ester resin is reacted with at least one mol. terminated with a moiety containing an active hydrogen. One example of mols. with a moiety terminated with an active hydrogen are amine terminated dimethylsiloxane. The resulting compound is heated and reacted with a difunctional cyanate ester resin and cured. The Tg of the final Cyanate Ester SMP can be matched to specific requirements by adjusting the ratio of the previous said elements and/or the addition of other agents to adjust the phys. properties of the final Cyanate Ester SMP. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Related Products of 78-26-2

The Article related to shape memory cyanate ester copolymer, Plastics Manufacture and Processing: Preparation Of Resins and other aspects.Related Products of 78-26-2

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