Month: November 2022

Santiago-Calvo, Mercedes; Naji, Haneen; Bernardo, Victoria; Martin-de Leon, Judith; Saiani, Alberto; Villafane, Fernando; Rodriguez-Perez, Miguel Angel published an article in 2021, the title of the article was Analysis of the Foaming Window for Thermoplastic Polyurethane with Different Hard Segment Contents.Recommanded Product: 111-29-5 And the article contains the following content:

A series of thermoplastic polyurethanes (TPUs) with different amounts of hard segments (HS) (40, 50 and 60 weight%) are synthesized by a pre-polymer method. These synthesized TPUs are characterized by Shore hardness, gel permeation chromatog. (GPC), differential scanning calorimetry (DSC), wide angle X-ray diffraction (WAXD), dynamic mech. thermal anal. (DMTA), and rheol. Then, these materials are foamed by a one-step gas dissolution foaming process and the processing window that allows producing homogeneous foams is analyzed. The effect of foaming temperature from 140 to 180°C on the cellular structure and on d. is evaluated, fixing a saturation pressure of 20 MPa and a saturation time of 1 h. Among the TPUs studied, only that with 50 weight% HS allows obtaining a stable foam, whose better features are reached after foaming at 170°C. Finally, the foaming of TPU with 50 weight% HS is optimized by varying the saturation pressure from 10 to 25 MPa at 170°C. The optimum saturation and foaming conditions are 25 MPa and 170°C for 1 h, which gives foams with the lowest relative d. of 0.74, the smallest average cell size of 4μm, and the higher cell nucleation d. of 8.0 x 109 nuclei/cm3. As a final conclusion of this investigation, the TPU with 50 weight% HS is the only one that can be foamed under the saturation and foaming conditions used in this study. TPU foams containing 50 weight% HS with a cell size below 15μ and porosity of 1.4-18.6% can be obtained using foaming temperatures from 140 to 180°C, saturation pressure of 20 MPa, and saturation time of 1 h. Varying the saturation pressure from 10 to 25 MPa and fixing the foaming temperature of 170°C and saturation pressure of 1 h results in TPU foams with a cell size of below 37μ and porosity of 1.7-21.2%. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Recommanded Product: 111-29-5

The Article related to thermoplastic polyurethane hard segment foaming window, foaming window, foams, gas dissolution foaming, hard segment, thermoplastic polyurethane, Plastics Fabrication and Uses: Plastic Product Uses and other aspects.Recommanded Product: 111-29-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, DaEun; Jin, Chowon; Kang, Hyo published an article in 2022, the title of the article was Vertical Alignment of Liquid Crystal on Sustainable 2,4-Di-tert-butylphenoxymethyl-Substituted Polystyrene Films.Reference of 2,4-Di-tert-butylphenol And the article contains the following content:

We synthesized sustainable 2,4-di-tert-butylphenoxymethyl-substituted polystyrenes (PDtBP#, # = 88, 68, 35, and 19, where # is molar percent contents of 2,4-di-tert-butylphenoxymethyl moiety), using post-polymerization modification reactions in order to study their liquid crystal (LC) alignment behaviors. In general, LC cells fabricated using polymer film with higher molar content of 2,4-di-tert-butylphenoxymethyl side groups showed vertical LC alignment behavior. LC alignment behavior in LC cell was related to the surface energy of the polymer alignment layer. For example, when the total surface energy value of the polymer layer was smaller than about 29.4 mJ/m2, vertical alignment behaviors were observed, generated by the nonpolar 2,4-di-tert-butylphenoxymethyl moiety with long and bulky carbon groups. Orientation stability was observed at 200°C in the LC cells fabricated using PDtBP88 as the LC alignment layer. Therefore, as a natural compound modified polymer, PDtBP# can be used as a candidate LC alignment layer for environmentally friendly applications. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Reference of 2,4-Di-tert-butylphenol

The Article related to butylphenoxymethyl substituted polystyrene film liquid crystal, 2,4-di-tert-butylphenol, liquid crystal, orientation layer, polystyrene, vertical, Plastics Fabrication and Uses: Plastic Product Uses and other aspects.Reference of 2,4-Di-tert-butylphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On October 4, 2007, Hannam, Joanne Clare; Hartmann, Sascha; Madin, Andrew; Ridgill, Mark Peter published a patent.Application of 386704-04-7 The title of the patent was Preparation of piperidines and related compounds as γ-secretase modulators for treatment of diseases associated with amyloid beta deposition in the brain. And the patent contained the following:

Title compounds [I; p = 0, 1; q = 0-3; V = bond, C atom bound to H, R2, XZ; W = N, C bound to H, R2, XZ; X = bond, C(R1)2, CH2C(R1)2; Y = bond, CH2, CH2CH2; Z = CO2H, tetrazolyl; R1 = H, nonaromatic hydrocarbyl; R1R1 = atoms to form an alicyclic group; R3, R4 = H; when V, W = C, then R3R4 = CH2CH2; R5 = H, alkyl, fluoroalkyl, alkoxy, fluoroalkoxy, alkenyl; R6 = Het-A; A = bond, CH2, 1,4-phenylene; Het = (substituted) heterocyclyl; R7 = hydrocarbyl optionally bearing a CF3 group; with provisos], were prepared Thus, 6-trifluoromethylnicotinaldehyde (preparation given), 2-methyl-1-buten-3-yne, Me [2-[4-(trifluoromethyl)phenyl]piperidin-4-yl]acetate hydrochloride (preparation given), and AuBr3 were microwaved together in H2O to give 64% ester derivative, which was saponified with LiOH in THF/H2O to give 71% title compound (II). In a cell-based γ-secretase assay, I showed IC50 values for inhibition of Aβ(42) production that were at least 2-fold lower than for Aβ(40). The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Application of 386704-04-7

The Article related to piperidineacetate preparation gamma secretase modulator, heteroarylmethyl pentenynyl piperidineacetate preparation amyloid beta disease treatment, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Application of 386704-04-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On July 17, 2012, Hannam, Joanne Clare; Hartmann, Sascha; Madin, Andrew; Ridgill, Mark Peter published a patent.Quality Control of (6-(Trifluoromethyl)pyridin-3-yl)methanol The title of the patent was Piperidines and related compounds for the treatment of dementia. And the patent contained the following:

Compounds of formula I: modulate the action of gamma secretase, and hence find use in treatment of Alzheimer’s disease and related conditions. The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Quality Control of (6-(Trifluoromethyl)pyridin-3-yl)methanol

The Article related to piperidineacetate preparation gamma secretase modulator, heteroarylmethyl pentenynyl piperidineacetate preparation amyloid beta disease treatment, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Quality Control of (6-(Trifluoromethyl)pyridin-3-yl)methanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On July 4, 2013, Xiao, Dengming; Zhu, Li; Hu, Yuandong; Yu, Rong; Hu, Wei; Zhao, Na; Peng, Yong; Luo, Hong; Han, Yongxin published a patent.Recommanded Product: 2-(Methylamino)ethan-1-ol hydrochloride The title of the patent was Preparation of ethylene derivatives as selective estrogen receptor regulators. And the patent contained the following:

The invention relates to ethylene derivatives I [wherein R0 and R1 = independently H, halo, alkyl, cycloalkyl, heterocyclyl, aryl, or heteroaryl; A and B = independently aryl or heteroaryl; R2 and R3 = independently halo, hydroxy, amino, cyano, mercapto, carboxyl, alkyl, alkenyl, alkynyl, etc.; m and n = independently 0-3], pharmaceutically acceptable salts, stereoisomers, solvates, polymorphs, tautomers, or prodrugs thereof as selective estrogen receptor modulators (SERMs) for treating atrophic vaginitis, endometriosis, female sex dysfunction, mammary cancer, depression, diabetes mellitus, osteoporosis, etc. For example, II was prepared in a multi-step synthesis. II showed inhibitory activity with IC50 < 100 nM against MCF-7 human breast cancer cell lines. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Recommanded Product: 2-(Methylamino)ethan-1-ol hydrochloride

The Article related to preparation pyridine pyrimidine selective estrogen receptor regulator human, treatment vaginitis endometriosis mammary cancer depression diabetes osteoporosis, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Recommanded Product: 2-(Methylamino)ethan-1-ol hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On July 18, 2012, Xiao, Dengming; Zhu, Li; Hu, Yuandong; Yu, Rong; Hu, Wei; Zhao, Na; Peng, Yong; Luo, Hong; Han, Yongxin published a patent.Formula: C3H10ClNO The title of the patent was Preparation of ethylene derivatives as selective estrogen receptor regulators. And the patent contained the following:

The invention relates to ethylene derivatives I [wherein R0 and R1 = independently H, halo, alkyl, cycloalkyl, heterocyclyl, aryl, or heteroaryl; A and B = independently aryl or heteroaryl; R2 and R3 = independently halo, hydroxy, amino, cyano, mercapto, carboxyl, alkyl, alkenyl, alkynyl, etc.; m and n = independently 0-3], pharmaceutically acceptable salts, stereoisomers, solvates, polymorphs, tautomers, or prodrugs thereof as selective estrogen receptor regulators for treating atrophic vaginitis, endometriosis, female sex dysfunction, mammary cancer, depression, diabetes mellitus, osteoporosis, etc. For example, II was prepared in a multi-step synthesis. II showed inhibitory activity with IC50 < 100 nM against MCF-7 human breast cancer cell lines. The experimental process involved the reaction of 2-(Methylamino)ethan-1-ol hydrochloride(cas: 62640-03-3).Formula: C3H10ClNO

The Article related to preparation pyridine pyrimidine selective estrogen receptor regulator human, treatment vaginitis endometriosis mammary cancer depression diabetes osteoporosis, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Formula: C3H10ClNO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On March 31, 2022, Quattrosoldi, Silvia; Guidotti, Giulia; Soccio, Michelina; Siracusa, Valentina; Lotti, Nadia published an article.Recommanded Product: Pentane-1,5-diol The title of the article was Bio-based and one-day compostable poly(diethylene 2,5-furanoate) for sustainable flexible food packaging: Effect of ether-oxygen atom insertion on the final properties. And the article contained the following:

In the present work, the effect of ether oxygen atom introduction in a furan ring-containing polymer has been evaluated. Solvent-free polycondensation process permitted the preparation of high mol. weight poly(diethylene 2,5-furandicarboxylate) (PDEF), by reacting the di-Me ester of 2,5-furandicarboxylic acid with diethylene glycol. After mol. and thermal characterization, PDEF mech. response and gas barrier properties to O2 and CO2, measured at different temperatures and humidity, were studied and compared with those of poly(butylene 2,5-furandicarboxylate) (PBF) and poly(pentamethylene 2,5-furanoate) (PPeF) previously determined Both PDEF and PPeF films were amorphous, differently from PBF one. As concerns mech. response, PDEF is more flexible than PBF but stiffer than PPeF. Moreover, PDEF is the most thermally stable (temperature of maximum degradation rate being 418 for PDEF, 407 for PBF and 414°C for PPeF) and hydrophilic (water contact angle being 74° for PDEF, 90° for PBF and 93° for PPeF), with gas barrier performances very similar to those of PPeF (O2 and CO2 transmission rate being 0.0022 and 0.0018 for PDEF and, 0.0016 and 0.0014 cm3 cm/m2 d atm for PPeF). Lab scale composting experiments indicated that PDEF and PPeF were compostable, the former degrading faster, in just one day. The results obtained are explained on the basis of the high electronegativity of ether oxygen atom with respect to the carbon one, and the consequent increase of dipoles along the macromol. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Recommanded Product: Pentane-1,5-diol

The Article related to polydiethylene furanoate compostable flexible food packaging, 2,5-furandicarboxylic acid, barrier properties, compostability, ether linkage, mechanical properties, Plastics Fabrication and Uses: Plastic Product Uses and other aspects.Recommanded Product: Pentane-1,5-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Weng, Can; Chen, Jiachen; Yang, Jin; Zhou, Mingyong; Jiang, Bingyan published an article in 2021, the title of the article was Experimental Investigation and Molecular Dynamics Simulation on the Anti-Adhesion Behavior of Alkanethiols on Nickel Insert in Micro Injection Molding.Formula: C10H22S And the article contains the following content:

Due to the adhesion between the polymer melt and nickel (Ni) mold insert in the micro injection molding process, deformation defects frequently occur when the microstructures are demolded from the insert. In this study, self-assembled alkanethiols were applied to modify the surface of Ni mold insert to reduce its surface energy. Exptl. trials were undertaken to explore the effect of alkanethiols coating on the replication quality. After that, mol. dynamics (MD) simulation was then used to investigate the adhesion behavior between the self-assembled coating and polypropylene (PP) by establishing three different types of alkanethiol material. The interaction energy, the potential energy change and radial distribution function were calculated to study the anti-adhesion mechanism. Exptl. results show that all the three coatings can effectively decrease the adhesion and therefore promote the replication fidelity. It is demonstrated in MD simulation that the adhesion mainly comes from the van der Waals (vdW) force at the interface. The arrangement of sulfur atom on the Ni surface results in different absorbing behaviors. Compared with that of the PP-Ni interface, the interfacial energy and adhesion work after surface treatment is significantly reduced. The experimental process involved the reaction of 1-Decanethiol(cas: 143-10-2).Formula: C10H22S

The Article related to alkanethiol anti adhesion mol dynamics simulation injection molding, anti-adhesion, micro injection molding, molecular dynamics simulation, self-assembled monolayers, Surface Chemistry and Colloids: Solid-Solid Systems and other aspects.Formula: C10H22S

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On April 30, 2020, De Jaco, Robert F.; Dorneles de Mello, Matheus; Nguyen, Huong Giang T.; Jeon, Mi Young; van Zee, Roger D.; Tsapatsis, Michael; Siepmann, Joern Ilja published an article.Synthetic Route of 111-29-5 The title of the article was Vapor- and liquid-phase adsorption of alcohol and water in silicalite-1 synthesized in fluoride media. And the article contained the following:

In this work, batch-adsorption experiments and mol. simulations are employed to probe the adsorption of binary mixtures containing ethanol or a linear alkane-1,n-diol solvated in water or ethanol onto silicalite-1. Since the batch-adsorption experiments require an addnl. relationship to determine the amount of solute (and solvent) adsorbed, as only the bulk liquid reservoir can be probed directly, mol. simulations are used to provide a relationship between solute and solvent adsorption for input to the exptl. bulk measurements. The combination of bulk exptl. measurements and simulated solute-solvent relationship yields solvent and solute loadings that are self-consistent with simulation alone, and allow for an assessment of the various assumptions made in the literature. At low solution concentrations, the solute loading calculated is independent of the assumption made. At high concentrations, a negligent choice of assumption can lead to systematic overestimation or underestimation of calculated solute loading. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Synthetic Route of 111-29-5

The Article related to adsorption ethanol water silicalite, Surface Chemistry and Colloids: Solid-Liquid Systems and other aspects.Synthetic Route of 111-29-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On December 5, 2020, Shumbula, Ndivhuwo P.; Ndala, Zakhele B.; Nkabinde, Siyabonga S.; Kolokoto, Tshwarela; Shumbula, Poslet M.; Mdluli, Phumlani S.; Hlatshwayo, Thulani; Mlambo, Mbuso; Moloto, Nosipho published an article.Name: 1-Decanethiol The title of the article was Experimental and theoretical studies of 1-alkanethiols SAMs of various chain-lengths on gold nanoparticles and their effect on SERS, stability and surface properties. And the article contained the following:

1-Alkanethiol SAMs on AuNPs have shown great potential towards the development of new functional materials. This is mainly due to the formation of dense, tightly bonded and well-ordered systems on the surface of AuNPs. This work showcases how the chain-length of 1-alkanethiols affects the stability and surface properties of AuNPs and the SERS effect. Using exptl. and theor. studies (by means of DFT), this work shows the interaction between 1-alkanethiols of 3 different chain-lengths and AuNPs. The effects on the optical properties, surface charge, stability and SERS were also investigated. The red shift of surface plasmon resonance band was observed as a result of the interaction between AuNPs and 1-alkanethioals. The Zeta potential indicated a strong electrostatic repulsion between AuNPs which was reduced after functionalizing with 1-alkanethiols. The long chain alkanethiol was found to strongly reduce the surface charge due to strong interaction with AuNPs. The calculated nucleophilic center cross-sections for all alkanethiols were found to increase with the chain-length, indicating a strong interaction existed between long chain alkanethiol and AuNPs. The SERS data shows an increase in Raman intensities of all 1-alkanethiols adsorbed on the surface of AuNPs. Both the exptl. and theor. data shows that the alkanethiol with short chain-length possesses the strongest Raman signal enhancement. The experimental process involved the reaction of 1-Decanethiol(cas: 143-10-2).Name: 1-Decanethiol

The Article related to gold thiol nanoparticle monolayer sers, Surface Chemistry and Colloids: Solid-Liquid Systems and other aspects.Name: 1-Decanethiol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts