Month: November 2022

On December 31, 2020, Ahmadi, Delaram; Mahmoudi, Najet; Li, Peixun; Ma, Kun; Doutch, James; Foglia, Fabrizia; Heenan, Richard K.; Barlow, David; Lawrence, M. Jayne published an article.Application of 111-29-5 The title of the article was Revealing the Hidden Details of Nanostructure in a Pharmaceutical Cream. And the article contained the following:

Creams are multi-component semi-solid emulsions that find widespread utility across a wide range of pharmaceutical, cosmetic, and personal care products, and they also feature prominently in veterinary preparations and processed foodstuffs. The internal architectures of these systems, however, have to date been inferred largely through macroscopic and/or indirect exptl. observations and so they are not well-characterized at the mol. level. Moreover, while their long-term stability and shelf-life, and their aesthetics and functional utility are critically dependent upon their mol. structure, there is no real understanding yet of the structural mechanisms that underlie the potential destabilizing effects of additives like drugs, anti-oxidants or preservatives, and no structure-based rationale to guide product formulation. In the research reported here we sought to address these deficiencies, making particular use of small-angle neutron scattering and exploiting the device of H/D contrast variation, with complementary studies also performed using bright-field and polarised light microscopy, small-angle and wide-angle X-ray scattering, and steady-state shear rheol. measurements. Through the convolved findings from these studies we have secured a finely detailed picture of the mol. structure of creams based on Aqueous Cream BP, and our findings reveal that the structure is quite different from the generic picture of cream structure that is widely accepted and reproduced in textbooks. The experimental process involved the reaction of Pentane-1,5-diol(cas: 111-29-5).Application of 111-29-5

The Article related to cosmetics nanostructure pharmaceutical cream, Pharmaceuticals: Formulation and Compounding and other aspects.Application of 111-29-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On December 31, 2010, Kumar, K. Ashok; Setty, S. Ramachandra; Narsu, Laxmi published an article.Application In Synthesis of 2-Methyl-2-propylpropane-1,3-diol The title of the article was Pharmacognostic and phytochemical investigations of roots of Hibiscus micranthus Linn. And the article contained the following:

The objective of the present investigation was determine the Pharmacognostical, physicochem. and phytochem. parameters as standardization markers for Hibiscus micranthus Linn. The macroscopic and microscopic characters, phys. constant values, extractive values, ash values, micro chem. anal. and fluorescence anal. were performed. The presence of lignified, thick wall, libiform type of fibers with pointed tips & vessel elements with oblique perforations plates having short, pointed tails, calcium oxalate druses are abundant in the phloem and periderm as seen in the powder/transverse sections of root were the distinguishing microscopic features and can be used as anatomical markers. Chemomicroscopic characters present included lignin, starch, suberin, mucilage, cellulose, protein bodies and calcium oxalate crystals. Phys. constants performed were loss on drying, ash content, acid insoluble ash and water soluble ash. Extractive values in pet. ether (60-80°C), chloroform, alc. and hydroalcoholic were determined Fluorescence studies of the powder were carried in ordinary light and UV light with various solvents. Phytochem. screening of successive extracts showed pos. reactions for steroids, flavonoids, carbohydrates, phenols and tannins. The fingerprints of the hydroalcoholic extract were obtained by HPTLC technique in three best mobile phase solvent systems. The flavonoid content of hydroalcoholic extract was determined by colorimetric method. Chem. profiling of hydroalcoholic extract was also performed by GC-MS anal. Further a HPLC method with photodiode array detector was followed to quantify rutin in hydroalcoholic extract of Hibiscus micranthus (HEHM). The present study provides details to characterize the Pharmacognostical, physicochem. and phytochem. parameters. An accurate and rapid HPLC quantification method has also been developed for quality control determination of rutin from Hibiscus micranthus roots. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Application In Synthesis of 2-Methyl-2-propylpropane-1,3-diol

The Article related to hibiscus root pharmacognosy physicochem phytochem, Plant Biochemistry: Composition and Products and other aspects.Application In Synthesis of 2-Methyl-2-propylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
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Wang, Ying; Xue, Tingting; Han, Xing; Guan, Lingxiao; Zhang, Liang; Wang, Hua; Li, Hua published an article in 2020, the title of the article was Kaolin particle film affects grapevine berry quality in cv. Meili in humid climate conditions.COA of Formula: C14H22O And the article contains the following content:

Kaolin particle film (KPF) is an aqueous formulation of chem. inert mineral particles that can be sprayed on the surface of crops to form a protective film, resulting in increased fruit yield and quality. In this work, the effects of kaolin-based, foliar reflectant particle film on grape composition and volatile compounds in ‘Meili’ (Vitis vinifera L.) grapes were investigated under different growth stages over two growing seasons. The 100-berry weight and titratable acid content were decreased, and the sugar and soluble solid contents were increased in grapes of plants treated with kaolin over 2 years. Compared with grapes from plants not sprayed with kaolin, the levels of total phenol, flavonoid, flavanol, tannin, and anthocyanins of grapes from plants treated with kaolin for 2 years were mostly increased. High-performance liquid chromatog. (HPLC) anal. also revealed an increased content of monomeric anthocyanin and changed anthocyanin composition However, there was little effect on the volatile compounds in the grapes. These results demonstrate that KPF can facilitate the accumulation of sugar and phenolics, thereby improving grape quality even in a humid climate. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).COA of Formula: C14H22O

The Article related to kaolin anthocyanin flavonoid temperature climate vitis, Plant Biochemistry: Composition and Products and other aspects.COA of Formula: C14H22O

Referemce:
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On August 31, 2021, Johns, Marcus A.; Nigmatullin, Rinat; Cranston, Emily D.; Eichhorn, Stephen J. published an article.Computed Properties of 585-88-6 The title of the article was The physicochemical effect of sugar alcohol plasticisers on oxidised nanocellulose gels and extruded filaments. And the article contained the following:

Oxidised nanocelluloses have previously shown promise for the production of extruded filaments with high tensile strength properties. However, they also exhibit poor wet strength due to swelling upon immersion in water. This has resulted in the use of chem. cross-linkers, or co-extrusion with multivalent cations, or cationic polymers, to inhibit this. Here, we report on the effect of incorporating sugar alcs. (glycerol, sorbitol and maltitol) in an oxidised nanocellulose gel before extrusion. While their presence weakens the initial gel, they enable the continuous wet spinning of filaments that are stable in aqueous media without the need for post extrusion processing. We conclude that the relative hydrophilicity of the sugar alc. and its ability to protonate surface carboxyl groups upon drying are key parameters regarding the physicochem. effects observed The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Computed Properties of 585-88-6

The Article related to physicochem sugar alc plasticiser nanocellulose gel filament, Pharmaceuticals: Formulation and Compounding and other aspects.Computed Properties of 585-88-6

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On March 31, 2016, Cai, Jiaqiang; Colandrea, Vincent; Crespo, Alejandro; Debenham, John; Du, Xiaoxing; Guiadeen, Deodialsingh; Liu, Ping; Liu, Rongqiang; Madsen-Duggan, Cristina B.; McCoy, Joshua G.; Quan, Weiguo; Sinz, Christopher; Wang, Liping published a patent.Related Products of 386704-04-7 The title of the patent was Inhibitors of HIF prolyl hydroxylase for use in enhancing erythropoietin production and treatment of anemia. And the patent contained the following:

The present invention concerns a compound of formula I or a pharmaceutically acceptable salt thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier. The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Related Products of 386704-04-7

The Article related to inhibitor hif prolyl hydroxylase erythropoietin anemia therapy, Pharmaceuticals: Formulation and Compounding and other aspects.Related Products of 386704-04-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On January 31, 2020, Rigane, Ghayth; Ben Salem, Ridha published an article.Formula: C8H8O3 The title of the article was Microwave-assisted extraction of hydroxytyrosol from alperujo and its impact on the stability of mayonnaise. And the article contained the following:

Extraction is one of the crucial steps for research and development of plant secondary metabolites. Microwave power and extraction time were selected as extraction parameters of hydroxytyrosol from alperujo. To achieve this goal, the optimization of phys. parameters was carried out by analyzing the obtained extracts using GC-MS apparatus Optimum conditions of microwave-assisted extraction based on maximum levels of responses were medium microwave power with 15 min of alperujo treatment. Maximum levels of hydroxytyrosol were obtained under these conditions (~1.9 g of hydroxytyrosol/kg of alperujo). Furthermore, we have studied the stability of mayonnaise after addition of hydroxytyrosol extract ranging between 65 and195μg by following the changes on free acidity, peroxide value, conjugated dienes as well as content of polyphenols and squalene. This study was conducted for 4 wk and the mayonnaise samples were stored protected from light at room temperature These results showed that 195μg of hydroxytyrosol rich extract may be of great benefit to improve the stability of the mayonnaise against oxidation The experimental process involved the reaction of 3-Hydroxyphenylacetic acid(cas: 621-37-4).Formula: C8H8O3

The Article related to hydroxytyrosol alperujo mayonnaise microwave assisted extraction, Pharmaceuticals: Formulation and Compounding and other aspects.Formula: C8H8O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On May 14, 2019, Sun, Changan; Gao, Peng; Liu, Lei; Bao, Rudi published a patent.Recommanded Product: 1-[(Dibenzylamino)methyl]cyclopropanol The title of the patent was Pharmaceutical composition containing fibroblast growth factor receptor 4 (FGFR4) inhibitor. And the patent contained the following:

The invention relates to a pharmaceutical composition containing a fibroblast growth factor receptor 4 (FGFR4) inhibitor, and in particular to a pharmaceutical composition containing a FGFR4 inhibitor having structure of formula (I). The pharmaceutical composition has high inhibiting effect on activity of FGFR4 kinase, and can be widely applied to preparation of pharmaceuticals for treating cancers, especially liver cancer, gastric cancer, prostatic cancer, skin cancer, ovarian cancer, lung cancer, breast cancer, colon cancer, pancreatic cancer, esophageal cancer, glioma or rhabdomyosarcoma. The experimental process involved the reaction of 1-[(Dibenzylamino)methyl]cyclopropanol(cas: 428855-17-8).Recommanded Product: 1-[(Dibenzylamino)methyl]cyclopropanol

The Article related to fibroblast growth factor receptor inhibitor antineoplastic cancer, Pharmaceuticals: Formulation and Compounding and other aspects.Recommanded Product: 1-[(Dibenzylamino)methyl]cyclopropanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On June 25, 2020, Gao, Zhisheng; Dance, Smruti A.; Taggi, Andrew E.; Bair, Joseph S. published a patent.Application of 78-26-2 The title of the patent was Low viscosity heat transfer fluids with increasing flash point and thermal conductivity. And the patent contained the following:

This disclosure relates to a heat transfer fluid having at least one first ester that is partially esterified, and at least one second ester that is fully esterified. The heat transfer fluid has a flash point from about 125°C to about 225°C as determined by ASTM D-93, and a kinematic viscosity (KV100) from about 1 to about 5 at 100°C as determined by ASTM D-445. The at least one first ester and the at least one second ester are present in an amount such that, as the flash point and thermal conductivity of the heat transfer fluid are increased, the kinematic viscosity (KV100) of the heat transfer fluid is decreased or essentially maintained. This disclosure also relates to a method for increasing flash point and thermal conductivity, while decreasing or essentially maintaining viscosity, of a heat transfer fluid by using the heat transfer fluid. The experimental process involved the reaction of 2-Methyl-2-propylpropane-1,3-diol(cas: 78-26-2).Application of 78-26-2

The Article related to low viscosity heat transfer fluid flash point thermal conductivity, Unit Operations and Processes: Heat Transfer and other aspects.Application of 78-26-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

On May 20, 2014, Taylor, Grahame N.; Matherly, Ron published an article.SDS of cas: 4719-04-4 The title of the article was Use of Portable Analytical Methods to Determine the Stoichiometry of Reaction for Hexahydrotriazine-Based Hydrogen Sulfide Scavenger Operations. And the article contained the following:

During the reaction between 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine and hydrogen sulfide, the principle byproduct is the organic sulfide 5-(2-hydroxyethyl)dithiazine. It can be determined by a novel, portable, field-capable ion mobility spectrometry method described herein and enables the degree spent to be determined Dependant upon the level of carbon dioxide in the produced gas, a mixture of ethanolaminium bicarbonate and ethanolamine bisulfide is also produced. Using a field capable spectrophotometric method the level of inorganic sulfide can be determined, thus allowing the ethanolaminium bisulfide concentration to be calculated Provided the fluid is only partially spent, and there is some unreacted 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine remaining; the only source of inorganic sulfide is the amine salt. From a knowledge of the original fluid concentration, the combination of these two methods allows the effective stoichiometry, or observed molar reaction proportions between 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine and hydrogen sulfide, to be measured for a specific field location. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).SDS of cas: 4719-04-4

The Article related to stoichiometry hexahydrotriazine hydrogen sulfide scavenger operation, Organic Analytical Chemistry: Determinations and other aspects.SDS of cas: 4719-04-4

Referemce:
Alcohol – Wikipedia,
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Malviya, Bhanwar Kumar; Verma, Ved Prakash; Sharma, Siddharth published an article in 2021, the title of the article was Electrochemical metal- and oxidant-free synthesis of S-thiocarbamates.Recommanded Product: 1-Decanethiol And the article contains the following content:

An expeditious synthetic strategy to access functionalized S-thiocarbamates was developed in good to excellent yields and with high current efficiencies. Readily available isocyanides and thiols were used as the starting materials under simple metal- and oxidant-free reaction conditions avoiding an inert atm. The practical application of the present methodol. was achieved by electrochem. synthesis of the herbicides prosulfocarb and pebulate. Furthermore, continuous electrochem. flow conditions using a graphite/Pt flow cell were used to obtain S-thiocarbamate compounds on a gram scale within a residence time of 35 min. The experimental process involved the reaction of 1-Decanethiol(cas: 143-10-2).Recommanded Product: 1-Decanethiol

The Article related to isocyanide thiol electrochem cross coupling, thiocarbamate preparation, General Organic Chemistry: Synthetic Methods and other aspects.Recommanded Product: 1-Decanethiol

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Alcohol – Wikipedia,
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