Month: November 2022

On February 24, 2022, Brix, Ann Cathrin; Dreyer, Maik; Koul, Adarsh; Krebs, Moritz; Rabe, Anna; Hagemann, Ulrich; Varhade, Swapnil; Andronescu, Corina; Behrens, Malte; Schuhmann, Wolfgang; Morales, Dulce M. published an article.Category: alcohols-buliding-blocks The title of the article was Structure-Performance Relationship of LaFe1-xCoxO3 Electrocatalysts for Oxygen Evolution, Isopropanol Oxidation, and Glycerol Oxidation. And the article contained the following:

Mitigating high energy costs related to sustainable H2 production via water electrolysis is important to make this process com. viable. Possible approaches are the investigation of low-cost, highly active oxygen evolution reaction (OER) catalysts and the exploration of alternative anode reactions, such as the electrocatalytic isopropanol oxidation reaction (iPOR) or the glycerol oxidation reaction (GOR), offering the possibility of simultaneously lowering the anodic overpotential and generating value-added products. A suitable class of catalysts are non-noble metal-based perovskites with the general formula ABO3, featuring rare-earth metal cations at the A- and transition metals at the B-site. We synthesized a series of LaFe1-xCoxO3 materials with x = 0-0.70 by automated co-precipitation at constant pH and subsequent calcination at 800°C. X-ray diffraction studies revealed that the phase purity was preserved in samples with x≤0.3. The activity towards the OER, iPOR, and GOR was investigated by rotating disk electrode voltammetry, showing a relation between structure and metal composition with the activity trends observed for the three reactions. Addnl., GOR product anal. via high-performance liquid chromatog. (HPLC) was conducted after 24 and 48 h electrolysis in a circular flow-through cell setup, pointing out a trade-off between activity and selectivity. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Category: alcohols-buliding-blocks

The Article related to lanthanum iron cobalt oxide isopropanol glycerol oxidation oer, Electrochemistry: Electrochemical Theory and other aspects.Category: alcohols-buliding-blocks

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On August 31, 2012, Lee, Sang S.; Hong, Dong K.; Jeong, Nam J.; Lee, Jeung H.; Choi, Yun-Seok; Lee, Ai-Young; Lee, Cheol-Heon; Kim, Kea J.; Park, Hae Y.; Yang, Jun-Mo; Lee, Ga-Young; Lee, Joon; Eun, Hee C.; Moon, Kee-Chan; Seo, Seong J.; Hong, Chang K.; Lee, Sang W.; Choi, Hae Y.; Lee, Jun Y. published an article.Product Details of 4719-04-4 The title of the article was Multicenter study of preservative sensitivity in patients with suspected cosmetic contact dermatitis in Korea. And the article contained the following:

As many new cosmetic products are introduced into the market, attention must be given to contact dermatitis, which is commonly caused by cosmetics. We investigate the prevalence of preservative allergy in 584 patients with suspected cosmetic contact dermatitis at 11 different hospitals. From Jan. 2010 to March 2011, 584 patients at 11 hospital dermatol. departments presented with cosmetic contact dermatitis symptoms. These patients were patch-tested for preservative allergens. An irritancy patch test performed on 30 control subjects using allergens of various concentrations showed high irritancy rates. Preservative hypersensitivity was detected in 41.1% of patients. Allergens with the highest pos. test rates were benzalkonium chloride (12.1%), thimerosal (9.9%) and methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) (5.5%). Benzalkonium chloride and chlorphenesin had the highest irritancy rate based on an irritancy patch test performed using various concentrations Seven of 30 normal subjects had a pos. irritant patch reading with 0.1 % benzalkonium chloride and eight of 30 normal subjects had a pos. irritant patch reading at 4 days with 0.5% chlorphenesin in petrolatum. Although benzalkonium chloride was highly pos. for skin reactions in our study, most reactions were probably irritation. MCI/MI and thimerosal showed highly pos. allergy reactions in our study. The optimum concentration of chlorphenesin to avoid skin reactions is less than 0.5%. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).Product Details of 4719-04-4

The Article related to cosmetic benzalkonium chloride merthiolate contact dermatitis preservative, Immunochemistry: Allergy and Anaphylaxis and other aspects.Product Details of 4719-04-4

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On October 12, 2020, Wang, Yue; Zhao, Xueqi; Yu, Zhi; Xu, Zhangrun; Zhao, Bing; Ozaki, Yukihiro published an article.COA of Formula: C8H9NO3 The title of the article was A chiral-label-free SERS strategy for the synchronous chiral discrimination and identification of small aromatic molecules. And the article contained the following:

A versatile and robust chiral discrimination strategy for small aromatic compounds is of significant importance in multidisciplinary fields. However, most current methods lack either the sufficient sensitivity for recognizing the chirality of the target mols. or their mol. specificity information. We have developed a versatile and chiral-label-free surface-enhanced Raman scattering (SERS)-based chiral discrimination sensing system for small aromatic mols., where the mol. structural specificity and enantioselectivity can be given synchronously in a single SERS spectrum. More than 10 types of chiral aromatic mols. were successfully identified by using this system. This work has enormous potential for recognizing chiral products effectively in sophisticated systems, especially in the fields of chiral synthesis and chiral catalysis. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).COA of Formula: C8H9NO3

The Article related to sers synchronous chiral discrimination aromatic compound, sers, charge transfer, chiral discrimination, small aromatic molecules, Organic Analytical Chemistry: Detections and other aspects.COA of Formula: C8H9NO3

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On June 30, 2021, Mayasich, Sally A.; Korte, Joseph J.; Denny, Jeffrey S.; Hartig, Phillip C.; Olker, Jennifer H.; DeGoey, Philip; O’Flanagan, Joseph; Degitz, Sigmund J.; Hornung, Michael W. published an article.Electric Literature of 96-76-4 The title of the article was Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals. And the article contained the following:

Deiodinase enzymes are critical for tissue-specific and temporal control of activation or inactivation of thyroid hormones during vertebrate development, including amphibian metamorphosis. We previously screened ToxCast chems. for inhibitory activity toward human recombinant Type 3 iodothyronine deiodinase enzyme (hDIO3) and subsequently produced Xenopus laevis recombinant dio3 enzyme (Xldio3) with the goals to identify specific chem. inhibitors of Xldio3, to evaluate cross-species sensitivity and explore whether the human assay results are predictive of the amphibian. We identified a subset of 356 chems. screened against hDIO3 to test against Xldio3, initially at a single concentration (200μM), and further tested 79 in concentration-response mode. Most chems. had IC50 values lower for hDIO3 than for Xldio3 and many had steep Hill slopes (a potential indication of non-specific inhibition). However, eight of the most potent chems. are likely specific inhibitors, with IC50 values of 14μM or less, Hill slopes near -1 and curves not significantly different between species likely due to conservation of catalytically active amino acids. Controlling for assay conditions, human in vitro screening results can be predictive of activity in the amphibian assay. This study lays the groundwork for future studies using recombinant non-mammalian proteins to test cross-species sensitivity to chems. The views expressed in this paper are those of the authors and do not necessarily reflect the views or policies of the U. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Electric Literature of 96-76-4

The Article related to xenopus human iodothyronine deiodinase screening endocrine disruptor, deiodinase, endocrine disruption, screening, thyroid, xenopus laevis, Toxicology: Methods (Including Analysis) and other aspects.Electric Literature of 96-76-4

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Formica, Michele; Sorin, Geoffroy; Farley, Alistair J. M.; Diaz, Jesus; Paton, Robert S.; Dixon, Darren J. published an article in 2018, the title of the article was Bifunctional iminophosphorane catalysed enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles.Formula: C7H6F3NO And the article contains the following content:

The first enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles, enabled by a bifunctional iminophosphorane (BIMP) organocatalyst, was described. The iminophosphorane moiety of the catalyst provided the required basicity to deprotonate the thiol nucleophile while the chiral scaffold and H-bond donor control facial selectivity. The reaction was broad in scope with respect to the thiol and benzimidazole reaction partners with the reaction proceeding in up to 98% yield and 96 : 4 er. The experimental process involved the reaction of (6-(Trifluoromethyl)pyridin-3-yl)methanol(cas: 386704-04-7).Formula: C7H6F3NO

The Article related to alkenyl benzimidazole alkanethiol iminophosphorane organocatalyst enantioselective sulfa michael addition, alkylthio alkyl benzimidazole preparation, Aliphatic Compounds: Ethers and Sulfides and other aspects.Formula: C7H6F3NO

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On February 28, 2018, Kamata, Ryo; Nakajima, Daisuke; Shiraishi, Fujio published an article.SDS of cas: 4719-04-4 The title of the article was Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay. And the article contained the following:

The constitutive androstane receptor (CAR) is a nuclear receptor and transcription factor regulating proteins involved in xenobiotic metabolism Agonist activation of the CAR can trigger metabolic activation and toxification as well as detoxification and clearance; accordingly, xenobiotic substances acting as CAR ligands may pose a threat to human and animal health. The authors used yeast cells transduced with the human CAR and the response pathway to measure the CAR-agonistic activities of 549 synthetic or natural compounds: 216 of the tested compounds exhibited CAR-agonistic effects. Eighty-four percent of CAR-activating compounds were aromatic compounds, and >65% of these active compounds were aromatic hydrocarbons, bisphenols, monoalkyl phenols, phthalates, styrene dimers, di-Ph ethers, organochlorines, and organophosphates. The ten most potent compounds were 4-tert-octylphenol (4tOP; reference substance), 4-nonylphenol, diethylstilbestrol, benzyl Bu phthalate, 2-(4-hydroxyphenyl)-2,4,4-trimethylchroman, o,p’-DDT, methoxychlor, di-Pr phthalate, hexestrol, and octachlorostyrene. The activities of these nine non-reference compounds exceeded 10% of the 4tOP activity. Anal. of para-monoalkyl phenols suggests that branching of the alkyl group and chlorination at the ortho position raises potency. This study provides critical information for identifying the potential of CAR-mediated toxic hazards and for understanding the relevant mechanism. The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).SDS of cas: 4719-04-4

The Article related to xenobiotic constitutive androstane receptor, alkyl phenol, bisphenol, constitutive androstane receptor, organochlorine, recombinant yeast, styrene dimer, Toxicology: Methods (Including Analysis) and other aspects.SDS of cas: 4719-04-4

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On July 21, 2010, Taylor, Grahame N.; Matherly, Ron published an article.HPLC of Formula: 4719-04-4 The title of the article was Gas chromatographic-mass spectrometric analysis of chemically derivatized hexahydrotriazine-based hydrogen sulfide scavengers: Part II. And the article contained the following:

A gas chromatog.-mass spectrometry method of assaying various thiadiazines and dithiazines in laboratory and field fluids is described. This method also involves the tris-trifluoroacetylation of anhydrous 5-(hydroxyethyl)dithiazine, which unexpectedly yields a novel derivative The experimental process involved the reaction of 2,2′,2”-(1,3,5-Triazinane-1,3,5-triyl)triethanol(cas: 4719-04-4).HPLC of Formula: 4719-04-4

The Article related to hexahydrotriazine derivative hydrogen sulfide scavenger reaction product gc ms, hydrogen sulfide hexahydrotriazine derivative reaction product analysis gc ms, Organic Analytical Chemistry: Detections and other aspects.HPLC of Formula: 4719-04-4

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On September 30, 2022, Carla Guimaraes Sobrinho, Alessandra; Silva Corpes, Rosana; Isabel Portilho dos Santos, Kyouk; Maria Menezes Barra, Ivoneide; Kiyoshi Miyagawa, Helder; Silva Santos, Alberdan published an article.Formula: C3H6O4 The title of the article was Untargeted GC-MS Metabolomics applied to wild leaves and callus produced by plant tissue culture of Hibiscus sabdariffa L.. And the article contained the following:

Hibiscus sabdariffa L. is a naturalized medicinal species in Brazil commonly called a “vinagreira” and is a member of the Malvaceae Juss. family, which has a rich potential of bioactive compounds presenting extracts with antioxidant, antibacterial, anti-inflammatory, hepatoprotective, antiviral, antidiabetic, and antiobesity, among others. The production of secondary metabolites of medicinal plants using biotechnol. tools such as the culture of callus of plant tissues is increasingly being used to produce high-quality compounds under in vitro conditions. From this perspective, the objective of this work was to analyze the chem. compounds of the leaves and callus culture of H. sabdariffa using techniques of Gas Chromatog. Coupled to the Mass Spectrum (GC-MS),. The anal. methodol. used consisted of removal of liposol. compounds, acid hydrolysis, and derivatization, all stages were submitted to ultrasonic-assisted agitation, using a reduced amount of biomass. Based on the results obtained in the study, a total of 38 metabolites identified by GC-MS anal. can be observed Among the identified substances, protocatechuic acid (26A) stands out as the main constituent, with a relative abundance of 26.86% and 16.68% for leaves and callus of H. sabdariffa, resp. The principal component anal. (PCA) allowed the discrimination of the chem. composition of each sample, being useful for the observation and detection of the compounds trends patterns. The anal. of the hierarchical group combined with the heat map represented the visual relationship between the samples of the data set indicating the values of higher and lower concentrations of chem. compounds resp., confirming that protocatechuic acid is the most abundant, for the leaves and callus of H. sabdariffa, followed by eicosanoid and isocitric acid, produced only in callus. It was concluded that the GC-MS technique combined with chemometric tools, helped identify the diversity of the compounds present in the leaves and callus of H. sabdariffa and that callus culture enables the production of bioactive compounds continuously and uniformly in a controlled environment and free of contamination. The experimental process involved the reaction of 2,3-Dihydroxypropanoic acid(cas: 473-81-4).Formula: C3H6O4

The Article related to hibiscus leaf callus tissue culture gcms metabolomics, Pharmaceuticals: Pharmacognostic Products and other aspects.Formula: C3H6O4

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On September 30, 2001, Shamsipur, Mojtaba; Poursaberi, Tahereh; Rouhani, Shohre; Niknam, Khodabakhsh; Sharghi, Hashem; Ganjali, Mohammad Reza published an article.Recommanded Product: 2160-93-2 The title of the article was Cobalt(II)-selective membrane electrode based on a recently synthesized benzo-substituted macrocyclic diamide. And the article contained the following:

A PVC-membrane electrode based on a recently synthesized 18-membered macrocyclic diamide is presented. The electrode reveals a Nernstian potentiometric response for Co2+ over a wide concentration range (2.0 × 10-6 – 1.0 × 10-2 M). The electrode has a response time of ∼10 s and can be used for at least 2 mo without any divergence. The proposed sensor revealed very good selectivities for Co2+ over a wide variety of other metal ions, and could be used over a wide pH range (3.0-8.0). The detection limit of the sensor is 6.0 × 10-7 M. It was successfully applied to the direct determination and potentiometric titration of Co ion. The experimental process involved the reaction of 2,2′-(tert-Butylazanediyl)diethanol(cas: 2160-93-2).Recommanded Product: 2160-93-2

The Article related to cobalt selective electrode benzo substituted macrocyclic diamide, Inorganic Analytical Chemistry: Apparatus and other aspects.Recommanded Product: 2160-93-2

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On August 30, 2013, Tang, Kewen; Wu, Guohui; Zhang, Panliang; Zhou, Congshan; Liu, Jiajia published an article.SDS of cas: 32462-30-9 The title of the article was Experimental and model study on enantioselective reactive extraction of p-hydroxyphenylglycine enantiomers with metal phosphine complexes. And the article contained the following:

Equilibrium study on enantioselective reactive extraction of p-hydroxyphenylglycine (HPG) enantiomers employing (S)-BINAP-metal complexes as host (selector) was performed in a batch system at 5°C. A reactive extraction model with an interfacial reaction of HPG enantiomers with (S)-BINAP-metal complexes was established to describe the exptl. data. The equilibrium formation constants at the interface and other important parameters were determined exptl. The extraction system shows good selectivity towards HPG enantiomers. Complex with palladium (PdCl2-(S)-BINAP) exhibits the highest selectivity among the metal complexes studied, which is solubilized in the organic phase and preferentially extracts L-HPG from aqueous phase. Efficiency of extraction depends, often strongly, on a number of process variables, including types of organic solvents and metal precursors, concentration of ligand, pH, and temperature The model quant. predicts extraction performance as a function of key operating parameters, providing a simple computational approach to process optimization. The model was verified exptl. with excellent results. The experimental process involved the reaction of H-Phg(4-OH)-OH(cas: 32462-30-9).SDS of cas: 32462-30-9

The Article related to hydroxyphenylglycine enantioselective reactive extraction metal phosphine complex exptl modeling, Organic Analytical Chemistry: Separations and other aspects.SDS of cas: 32462-30-9

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