Month: November 2022

Chemical constituents from Semiliquidambar chingii and their chemotaxonomic significance was written by Zhang, Jingyi;Kaliaperumal, Kumaravel;Liu, Ziyue;Zhang, Jun. And the article was included in Biochemical Systematics and Ecology in 2022.Safety of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

The present study investigated the phytochem. constituents of Semiliquidambar chingii for the first time, resulting in the isolation and characterization of nineteen compounds which were categorized into eight groups as resveratrol derivatives (1-4), triterpenoids (5-10), flavonoids (11-13), phenolic glycosides (14-15), lignan (16), ellagic acid derivative (17), coniferyl alc. derivative (18), and shikimic acid derivative (19). The chem. structures of these compounds were elucidated based on the careful anal. of spectroscopic data and comparison with reported data. This is the first report of isolation of compounds 1-19 from S. chingii and compounds 1-4, 5-7, 9-11, and 14-19 within the genus Semiliquidambar. Furthermore, the chemotaxonomic significance of the isolates was discussed in detail, which might provide important chem. taxonomic evidence supporting the hybrid origin of Semiliquidambar from the genera Altingia and Liquidambar. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Safety of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol).

(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Separation and identification of phospholipids by hydrophilic interaction liquid chromatography coupled to tandem high resolution mass spectrometry with focus on isomeric phosphatidylglycerol and bis(monoacylglycero)phosphate was written by Vosse, Christian;Wienken, Carina;Cadenas, Cristina;Hayen, Heiko. And the article was included in Journal of Chromatography A in 2018.HPLC of Formula: 923-61-5 The following contents are mentioned in the article:

Changes in lipid composition of cells or tissue are often linked to various diseases. Studies indicate alterations of bis(monoacylglycero)phosphate (BMP) species in diseases such as cancer. Therefore, an extended phospholipid profiling method based on hydrophilic interaction liquid chromatog. (HILIC) coupled to high-resolution mass spectrometry (MS) and data-dependent MS/MS acquisition was developed to sep. and unambiguously identify BMP species. Lipid species identification was based on retention time, accurate mass and specific MS/MS fragments. The developed method was applied in a proof of concept study to lipid extracts of a cell culture model of conditional oncogene overexpression in MCF-7/NeuT breast cancer cells. Comparison of control and oncogene-induced MCF-7/NeuT breast cancer cells showed changes in BMP species distribution. Thereby, a shift from long-chain to shorter-chain fatty acid composition in BMP species was detected. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5HPLC of Formula: 923-61-5).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 923-61-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A General Strategy for the Synthesis of Cyclic N-Aryl Hydroxamic Acids via Partial Nitro Group Reduction was written by McAllister, Laura A.;Bechle, Bruce M.;Dounay, Amy B.;Evrard, Edelweiss;Gan, Xinmin;Ghosh, Somraj;Kim, Ji-Young;Parikh, Vinod D.;Tuttle, Jamison B.;Verhoest, Patrick R.. And the article was included in Journal of Organic Chemistry in 2011.SDS of cas: 1290618-00-6 The following contents are mentioned in the article:

We describe a generalized approach to stereocontrolled synthesis of substituted cyclic hydroxamic acids (3-amino-1-hydroxy-3,4-dihydroquinolinones), e.g. I (R = F₃CO, MeO, Me, Cl), by selective reduction of substituted 2-nitrophenylalanine substrates. Compounds in this series have antibacterial properties and have also recently been reported as KAT II inhibitors. The key nitrophenyl alanine intermediates are prepared enantioselectively in excellent yield by phase transfer catalyzed alkylation of the corresponding nitrobenzyl bromides. The scope and limitations of the reductive cyclization transformation have been explored with attention to the effects of substitution pattern and electronics on reaction efficiency and byproduct formation. In addition, a novel activated trifluoroethyl ester cyclization strategy has been developed as an alternate approach to the most sterically demanding systems in this series. This study involved multiple reactions and reactants, such as (2-Nitro-5-(trifluoromethoxy)phenyl)methanol (cas: 1290618-00-6SDS of cas: 1290618-00-6).

(2-Nitro-5-(trifluoromethoxy)phenyl)methanol (cas: 1290618-00-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.SDS of cas: 1290618-00-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Post-veraison different frequencies of water deficit strategies enhance Reliance grapes quality under root restriction was written by Leng, Feng;Zhou, Jialing;Wang, Chengyang;Sun, Liping;Zhang, Yue;Li, Youmei;Wang, Lei;Wang, Shiping;Zhang, Xianan;Xie, Zhaosen. And the article was included in Food Chemistry in 2022.Quality Control of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol The following contents are mentioned in the article:

In this study, two water deficit treatments in the same amount of water but with different frequencies (T1: 2.5 L per 4 d and T2: 5 L per 8 d) were performed on Reliance grapevines from veraison until harvest to explore their effects on grape berries quality under root restriction. Results showed that glucose, fructose and sucrose contents were increased, while malic acid, tartaric acid and citric acid contents were decreased under two treatments. Meanwhile, water deficits also promoted the accumulation of phenylalanine and proline. For phenols, anthocyanins, resveratrol and flavonols contents in the water deficit groups were significantly higher than those in the control group. In addition, two water deficit treatments increased the characteristic aromas contents, especially the esters contents. Overall, T2 treatment had a better effect than T1 treatment. This study provided an idea for improving water use efficiency and grape quality. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Quality Control of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol).

(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of high-performance waterborne polyester was written by Liang, Nai-jie;Xiang, Jin-yang;Xu, Zhen-yang;He, Tao;Zeng, Ding;Xu, Yi-xiang;Yao, Huang;Zhang, Jie;Yu, Lin;Yu, Qian. And the article was included in Reguxing Shuzhi in 2015.HPLC of Formula: 115-84-4 The following contents are mentioned in the article:

The waterborne polyester was synthesized by melt polycondensation of secondary polyol, tertiary alc. and polybasic acid. The waterborne polyester-amino drying paint was prepared Effects of molar ratio of hydroxyl to carboxyl groups, 1, 4-cyclohexanedicarboxylic acid and trimethylolpropane dosages and cosolvent on the properties of water-based resins and coatings were investigated by viscosity and pH testings, gel chromatog. and IR spectroscopy anal. and determination of coating properties. The results showed that the resins and coatings had optimal performance as the conditions as followed: molar ratio of hydroxy to carboxyl 1.1:1, 1, 4-cyclohexane dicarboxylic acid(based on the molar of total acid) dosage of 6%, trimethylolpropane(based on the molar of total alc.) dosage of 12% and glycol monobutyl ether used as cosolvent. The coatings had good water resistance (boiling water, 2 h), storage stability (40°C, 14 d)and solvent resistance. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4HPLC of Formula: 115-84-4).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 115-84-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Optimization of an Inclusion Body-Based Production of the Influenza Virus Neuraminidase in Escherichia coli was written by Lipnicanova, Sabina;Legerska, Barbora;Chmelova, Daniela;Ondrejovic, Miroslav;Miertus, Stanislav. And the article was included in Biomolecules in 2022.Product Details of 367-93-1 The following contents are mentioned in the article:

Neuraminidase (NA), as an important protein of influenza virus, represents a promising target for the development of new antiviral agents for the treatment and prevention of influenza A and B. Bacterial host strain Escherichia coli BL21 (DE3)pLysS containing the NA gene of the H1N1 influenza virus produced this overexpressed enzyme in the insoluble fraction of cells in the form of inclusion bodies. The aim of this work was to investigate the effect of independent variables (propagation time, iso-Pr beta-d-1-thiogalactopyranoside (IPTG) concentration and expression time) on NA accumulation in inclusion bodies and to optimize these conditions by response surface methodol. (RSM). The maximum yield of NA (112.97 ± 2.82 U/g) was achieved under optimal conditions, namely, a propagation time of 7.72 h, IPTG concentration of 1.82 mM and gene expression time of 7.35 h. This study demonstrated that bacterially expressed NA was enzymically active. This study involved multiple reactions and reactants, such as (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1Product Details of 367-93-1).

(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol (cas: 367-93-1) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Product Details of 367-93-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dynamic mechanical properties of poly(tetramethylene ether) glycol polyurethanes: effect of diol-chain extender structure was written by Duffy, James V.;Lee, Gilbert F.;Lee, John D.;Hartmann, Bruce. And the article was included in ACS Symposium Series in 1990.SDS of cas: 115-84-4 The following contents are mentioned in the article:

The steric effect that pendant groups present in the diol chain extender have on the glass (T_g) and m.p. (T_m) transitions and dynamic mech. properties of some PTMG polyurethanes was studied. A series of poly(tetramethylene ether) glycol/4,4′-diphenylmethane diisocyanate prepolymers were extended with diols that contained either Me, Et, or Bu pendant groups. Differential scanning calorimetry (DSC) was used to determine the T_g and T_m of the soft and hard phases. It was found that diol pendant groups increased the amount of phase mixing in the soft segment while preventing crystallization in both the soft and hard segments. The effect of diol pendant groups on the shear modulus and loss factor of these polyurethanes was determined by a resonance technique. The size of the pendant group had no apparent effect on either T_g, T_m, or the dynamic mech. properties of these polymers. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4SDS of cas: 115-84-4).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.SDS of cas: 115-84-4

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bitter almond gum reduces body mass index, serum triglyceride, hyperinsulinemia and insulin resistance in overweight subjects with hyperlipidemia was written by Chahibakhsh, Negar;Hosseini, Ebrahim;lslam, Shahidul Md.;Rahbar, Ali Reza. And the article was included in Journal of Functional Foods in 2019.Related Products of 106-21-8 The following contents are mentioned in the article:

The aim of this study was to compare the effects of different gums on glycemic and lipidemic parameters in patients with hyperlipidemia. Sixty patients were divided into four groups of 15 individuals in each group. Group 1 was selected as control. Groups 2, 3, and 4 consumed 300 mL of apple juice enriched with bitter almond, tragacanth and xanthan gum, resp. After 6-wk intervention, the bodyweight, BMI, serum TG, hyperinsulinemia and HOMA-IR were significantly decreased in the subjects consumed bitter almond gum-enriched juice when no significant differences were observed for other parameters. The effect of bitter almond gum was better than tragacanth and xanthan gum in all parameters tested. The findings of this study suggest that some of the identified bioactive compounds in bitter almond gum might be responsible for its effects and it can be a possible food supplements for the better management of overweight, obesity and hyperlipidemia. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Related Products of 106-21-8).

3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Related Products of 106-21-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Perfluorohexyloctane (F₆H₈) as a delivery agent for cyclosporine A in dry eye syndrome therapy – Langmuir monolayer study complemented with infrared nanospectroscopy was written by Chachaj-Brekiesz, Anna;Wnetrzak, Anita;Lipiec, Ewelina;Kobierski, Jan;Dynarowicz-Latka, Patrycja. And the article was included in Colloids and Surfaces, B: Biointerfaces in 2019.Recommanded Product: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

One of the key challenges in dry eye syndrome therapy is to find a suitable carrier for immunosuppressant drug – cyclosporine A (CsA) – delivery to the eye. To investigate this issue, herein we present a methodol. based on the combined anal. in macro- (Langmuir monolayers), micro- (Brewster angle microscopy) and nanoscale (at. force microscopy and IR nano-spectroscopy). The applied approach proves that CsA affects the phospholipid part of the tear film lipid layer by loosening mol. packing. This effect can be reversed by the addition of perfluorohexyloctane (F₆H₈). We have highlighted that F₆H₈ increases the availability of CsA and therefore is appropriate carrier for CsA topical delivery to the eye in the dry eye syndrome. In addition, the applied herein procedure provides a simple, low-cost laboratory tool for preliminary studies involving membrane active pharmaceuticals, preceding in vivo tests. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Recommanded Product: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tick-repellent investigations at Bull’s Island, S.C., 1948 was written by Cole, Moses M.;Smith, Carroll N.. And the article was included in Journal of Economic Entomology in 1949.Name: 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:

cf. C.A. 44, 1641i; King, C.A. 43, 9349a. Various repellents, applied to regulation U.S. army fatigue uniforms, were tested in areas heavily infested with lone star ticks (Amblyomma americanum). The Bu ester of 3,4-dihydro-2,2-dimethyl-4-oxo-1,2H-pyran-6-carboxylic acid (Indalone) (I), 2-phenoxyethyl isobutyrate, hexyl mandelate, and Et β-phenylhydracrylate were most effective and safe for use on the human skin or on clothing. I was the most consistently effective of these compounds Outstanding in effectiveness alone were 2-[2-(2-ethylhexyloxy)ethoxy]ethanol (II) and N-amyl-α-butoxyacetamide, 2-butyl-2-ethyl-1,3-propanediol, and di-Me cis-bicyclo[2.2.1]-5-heptene-2,3-dicarboxylate (III). Some of these caused some skin irritation. Acetone solutions of I produced better impregnation of garments than I emulsions; the solutions and emulsions of II and III gave about equal impregnation. I and II powders protected uniforms through a single wearing. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Name: 2-Butyl-2-ethylpropane-1,3-diol).

2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 2-Butyl-2-ethylpropane-1,3-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts