Month: November 2022

In 2017,Li, Lei; Gong, Tianjun; Lu, Xi; Xiao, Bin; Fu, Yao published 《Nickel-catalyzed synthesis of 1,1-diborylalkanes from terminal alkenes》.Nature Communications published the findings.HPLC of Formula: 78782-17-9 The information in the text is summarized as follows:

Organoboron compounds play an irreplaceable role in synthetic chem. and the related transformations based on the unique reactivity of C-B bond are potentially the most efficient methods for the synthesis of organic mols. The synthetic importance of multiboron compounds in C-C bond formation and function transformation reactions is growing and the related borations of activated or nonactivated alkenes have been developed recently. However, introducing directly two boron moieties into the terminal sites of alkenes giving 1,1-diborylalkanes in a catalytic fashion has not been explored yet. Here authors describe a synthetic strategy of 1,1-diborylalkanes via a Ni-catalyzed 1,1-diboration of readily available terminal alkenes. This methodol. shows high level of chemoselectivity and regioselectivity and can be used to convert a large variety of terminal alkenes, such as vinylarenes, aliphatic alkenes and lower alkenes, to 1,1-diborylalkanes.Bis[(pinacolato)boryl]methane(cas: 78782-17-9HPLC of Formula: 78782-17-9) was used in this study.

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds. Organoboron compounds have been a cornerstone of synthetic transformations for decades. Areas such as boron-containing catalysts, metalate chemistry, photoredox methods, and boryl anions have brought significant new developments in understanding and provided new reactivity upon.HPLC of Formula: 78782-17-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2018,Cai, Wangshui; Wang, Shuang; Jalani, Hitesh B.; Wu, Junxian; Lu, Hongjian; Li, Guigen published 《Oxidative Cascade Reaction of N-Aryl-3-alkylideneazetidines and Carboxylic Acids: Access to Fused Pyridines》.Organic Letters published the findings.Application of 18621-18-6 The information in the text is summarized as follows:

A versatile silver-promoted oxidative cascade reaction of N-aryl-3-alkylideneazetidines with carboxylic acids is reported, providing a very efficient pathway to functionalized fused pyridines. This method allows introduction of fused pyridine ring systems to heterocycles, drugs, and natural products. A mechanistic study revealed that silver salt is essential for the chemo- and regioselective ring expansion, sequential oxidative nucleophilic additions, and oxidative aromatization. This approach represents the first example of the strained N-heterocycles undergoing a cascade reaction with a π bond and a nucleophile together.Azetidin-3-ol hydrochloride(cas: 18621-18-6Application of 18621-18-6) was used in this study.

Azetidin-3-ol hydrochloride(cas:18621-18-6) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Application of 18621-18-6 Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2018,Dey, Subal; Ahmed, Estak Md; Dey, Abhishek published 《Activation of Co(I) State in a Cobalt-Dithiolato Catalyst for Selective and Efficient CO2 Reduction to CO》.Inorganic Chemistry published the findings.Name: 2,6-Pyridinedimethanol The information in the text is summarized as follows:

Reduction of CO2 holds the key to solving 2 major challenges taunting the society-clean energy and clean environment. There is an urgent need for the development of efficient nonnoble metal-based catalysts that can reduce CO2 selectively and efficiently. Unfortunately, activation and reduction of CO2 can only be achieved by highly reduced metal centers jeopardizing the energy efficiency of the process. A CO dehydrogenase inspired Co complex bearing a dithiolato ligand can reduce CO2, in wet MeCN, to CO with ∼95% selectivity over a wide potential range and 1559 s-1 rate with a remarkably low overpotential of 70 mV. Unlike most of the transition metal-based systems that require reduction of the metal to its formal zerovalent state for CO2 reduction, this catalyst can reduce CO2 in its formal +1 state making it substantially more energy efficient than any system known to show similar reactivity. While covalent donation from 1 thiolate increases electron d. at the Co(I) center enabling it to activate CO2, protonation of the bound thiolate, in the presence of H2O as a proton source, plays a crucial role in lowering overpotential (thermodn.) and ensuring facile proton transfer to the bound CO2 ensuring facile (kinetics) reactivity. A very covalent Co(III)-C bond in a Co(III)-COOH intermediate is at the heart of selective protonation of the O atoms to result in CO as the exclusive product of the reduction In the experiment, the researchers used many compounds, for example, 2,6-Pyridinedimethanol(cas: 1195-59-1Name: 2,6-Pyridinedimethanol)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Name: 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Nature Communications included an article by Wang, Dan; Wang, Pan; Wang, Shengchun; Chen, Yi-Hung; Zhang, Heng; Lei, Aiwen. Product Details of 873-75-6. The article was titled 《Direct electrochemical oxidation of alcohols with hydrogen evolution in continuous-flow reactor》. The information in the text is summarized as follows:

Herein, an electrochem. oxidation of various alcs. in a continuous-flow reactor without external oxidants, base or mediators to afford aldehydes or ketones was reported. The robust electrochem. oxidation was performed for a variety of alcs. with good functional group tolerance, high efficiency and atom economy, whereas mechanistic studies support the benzylic radical intermediate formation and hydrogen evolution. The electrochem. oxidation proved viable on diols with excellent levels of selectivity for the benzylic position. In the part of experimental materials, we found many familiar compounds, such as (4-Bromophenyl)methanol(cas: 873-75-6Product Details of 873-75-6)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Product Details of 873-75-6 It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Organic Letters included an article by Wang, Xiao-Xu; Li, Lei; Gong, Tian-Jun; Xiao, Bin; Lu, Xi; Fu, Yao. HPLC of Formula: 78782-17-9. The article was titled 《Vicinal Diboration of Alkyl Bromides via Tandem Catalysis》. The information in the text is summarized as follows:

Vicinal diboration of alkyl bromides via tandem catalysis is reported. The reported reaction exhibits a broad substrate scope, good functional group compatibility, and regioselectivity. Also, it shows good practicality due to the easy accessibility of alkyl bromides in combination with diverse transformations of diboronates. Mechanism study indicates that terminal alkenes are generated selectively through Ni-catalyzed dehydrohalogenation of alkyl bromides followed by base/MeOH promoted diboration process to provide 1,2-diboration products. The experimental process involved the reaction of Bis[(pinacolato)boryl]methane(cas: 78782-17-9HPLC of Formula: 78782-17-9)

Bis[(pinacolato)boryl]methane(cas: 78782-17-9) belongs to organoboron compounds. Organoboron compounds have been a cornerstone of synthetic transformations for decades. Areas such as boron-containing catalysts, metalate chemistry, photoredox methods, and boryl anions have brought significant new developments in understanding and provided new reactivity upon.HPLC of Formula: 78782-17-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,ACS Catalysis included an article by Bains, Amreen K.; Kundu, Abhishek; Yadav, Sudha; Adhikari, Debashis. Computed Properties of C7H9NO2. The article was titled 《Borrowing Hydrogen-Mediated N-Alkylation Reactions by a Well-Defined Homogeneous Nickel Catalyst》. The information in the text is summarized as follows:

We report herein a well-defined and bench-stable azo-phenolate ligand-coordinated nickel catalyst which can efficiently execute N-alkylation of a variety of anilines by alc. We demonstrate that the redox-active azo ligand can store hydrogen generated during alc. oxidation and redelivers the same to an in-situ-generated imine bond to result in N-alkylation of amines. The reaction has wide scope, and a large array of alcs. can directly couple to a variety of anilines. Mechanistic studies including deuterium labeling to the substrate establishes the borrowing hydrogen method from alcs. and pinpoints the crucial role of the redox-active azo moiety present on the ligand backbone. Isolation of the ketyl intermediate in its trapped form with a radical quencher and higher kH/kD for the alc. oxidation step suggest altogether a hydrogen-atom transfer (HAT) to the reduced azo backbone to pave alc. oxidation as opposed to the conventional metal-ligand bifunctional mechanism. This example clearly demonstrates that an inexpensive base metal catalyst can accomplish an important coupling reaction with the help of a redox-active ligand backbone. The results came from multiple reactions, including the reaction of 2,6-Pyridinedimethanol(cas: 1195-59-1Computed Properties of C7H9NO2)

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Computed Properties of C7H9NO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,RSC Advances included an article by Walia, Preet Kamal; Sharma, Manik; Kumar, Manoj; Bhalla, Vandana. Related Products of 873-75-6. The article was titled 《UV light promoted ‘Metal’/’Additive’-free oxidation of alcohols: investigating the role of alcohols as electron donors》. The information in the text is summarized as follows:

UV light promoted selective oxidation of primary and secondary alcs. RCH(R1)OH [R = Ph, cyclohexyl, thiophen-2-yl, etc.; R1 = H, Ph, Me; RR1 = -(CH2)5-], 1,3-benzenedimethanol and 9H-fluoren-9-ol has been demonstrated under ‘metal-free’ and ‘additive-free’ conditions. Under the optimized conditions, a variety of aromatic, heteroaromatic, and alicyclic alcs. have been examined for their transformations to the corresponding carbonyl compounds RC(O)R1, isophthalaldehyde and 9H-fluoren-9-one. The mechanistic studies emphasize the important role of substrate (alc.) and solvent (DMSO) in the generation of superoxide radical which is a vital intermediate for the transformation. This study also highlights the role of air as the oxidant in the oxidation process. Further, the practical application of the strategy has also been demonstrated for the oxidation of the alc. moiety in cholesterol. In addition to this study using (4-Bromophenyl)methanol, there are many other studies that have used (4-Bromophenyl)methanol(cas: 873-75-6Related Products of 873-75-6) was used in this study.

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Related Products of 873-75-6 It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Organic Letters included an article by Khan, Sardaraz; Li, Hongfang; Zhao, Can; Wu, Xue; Zhang, Yong Jian. Recommanded Product: 2,6-Pyridinedimethanol. The article was titled 《Asymmetric Allylic Etherification of Vinylethylene Carbonates with Diols via Pd/B Cooperative Catalysis: A Route to Chiral Hemi-Crown Ethers》. The information in the text is summarized as follows:

Pd-catalyzed regio- and enantioselective allylic etherification of vinylethylene carbonates (VECs) with diols has been developed. By using cooperative catalysts of the chiral palladium complex and triethylborane in mild conditions, the process gave monoetherified and bisetherified polyglycol derivatives with tetrasubstituted stereocenters in high yields with complete regioselectivities and high levels of enantio- and diastereoselectivities. In addition to this study using 2,6-Pyridinedimethanol, there are many other studies that have used 2,6-Pyridinedimethanol(cas: 1195-59-1Recommanded Product: 2,6-Pyridinedimethanol) was used in this study.

2,6-Pyridinedimethanol(cas: 1195-59-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Recommanded Product: 2,6-Pyridinedimethanol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Catalysis Letters included an article by Dutta, Apurba; Chetia, Mitali; Ali, Abdul A.; Bordoloi, Ankur; Gehlot, Praveen S.; Kumar, Arvind; Sarma, Diganta. Product Details of 821-41-0. The article was titled 《Copper Nanoparticles Immobilized on Nanocellulose: A Novel and Efficient Heterogeneous Catalyst for Controlled and Selective Oxidation of Sulfides and Alcohols》. The information in the text is summarized as follows:

In this work, we have described the versatility of low metal loading copper nanoparticles immobilized on nanocellulose for the controlled and selective oxidation of sulfides to sulfoxides and primary alcs. to aldehydes using green oxidant at room temperature Aromatic, aliphatic and heterocyclic sulfides were oxidized to their corresponding sulfoxides with high yields without formation of over oxidized sulfones. Similarly, benzylic, allylic and aliphatic alcs. were selectively oxidized to aldehydes without traces of carboxylic acids in good to excellent yields. In addition to this study using 5-Hexen-1-ol, there are many other studies that have used 5-Hexen-1-ol(cas: 821-41-0Product Details of 821-41-0) was used in this study.

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Product Details of 821-41-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Preparation of Heterocycles via Visible-Light-Driven Aerobic Selenation of Olefins with Diselenides》 were Zhang, Qing-Bao; Yuan, Pan-Feng; Kai, Liang-Lin; Liu, Kai; Ban, Yong-Liang; Wang, Xue-Yang; Wu, Li-Zhu; Liu, Qiang. And the article was published in Organic Letters in 2019. Name: 5-Hexen-1-ol The author mentioned the following in the article:

The aerobic dehydrogenative cyclization of alkenes with easily accessible diselenides facilitated by visible light is reported. Notably, the features of this transition-metal-free protocol are pronounced efficiency and practicality, good functional group tolerance, atom economy, and high sustainability, since ambient air and visible light are adequate for the clean construction of five- and six membered heterocycles in yields of up to 98%. After reading the article, we found that the author used 5-Hexen-1-ol(cas: 821-41-0Name: 5-Hexen-1-ol)

5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.Name: 5-Hexen-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts