Month: October 2022

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 647-42-7, formula is C8H5F13O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Synthetic Route of 647-42-7

Lai, Thanh T.;Eken, Yigitcan;Wilson, Angela K. research published 《 Binding of Per- and Polyfluoroalkyl Substances to the Human Pregnane X Receptor》, the research content is summarized as follows. Per- and polyfluoroalkyl substances (PFASs) are a class of environmentally persistent industrial compounds that disrupt various metabolic pathways. Among the protein receptors to which PFASs bind, the human pregnane X receptor (hPXR) is found to be a host for a variety of long- and short-chain PFASs that lead to its overactivation. Overactivation of hPXR is linked to potential endocrine disruption, oxidative stress, hepatic steatosis, and adverse drug interactions. In this study, mol. dynamics (MD) is used to study the binding between hPXR and a number of PFAS compounds, including alternatives whose activity on hPXR has not been exptl. tested. This is the first-time MD is used to study the interactions between PFASs and hPXR, showing how relative binding free energies of PFASs relate to hPXR agonism. Binding free energy calculations, hydrogen bond anal., per-residue decomposition calculations, and alanine scanning studies are done to provide further insight. Activities on hPXR for several short-chain and alternative PFAS compounds to long-chain PFASs that have yet to be reported will also be considered. These short-chain and alternative species include perfluorobutane sulfonic acid (PFBS), Gen-X (trade name for 2,3,3,3-tetrafluoro-2-heptafluoropropoxy propanoic acid), ADONA (trade name for 4,8-dioxa-3H-perfluorononanoic acid), and 6:2 fluorotelomer carboxylic acid (6:2 FTCA). The study shows key aspects of PFAS recognition on the hPXR, the link between PFAS binding to hPXR and the hPXR activity change observed upon the PFAS exposure, and the potential effects of alternative PFASs on hPXR activity.

Synthetic Route of 647-42-7, 3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-ol, also known as 1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol , is a useful research compound. Its molecular formula is C8H5F13O and its molecular weight is 364.1 g/mol. The purity is usually 95%.

1H,1H, 2H, 2H-Tridecafluoro-1-n-octanol is a material used to improve nanotube composites. It is also used in the synthesis of a recyclable fluorous hydrazine carbothioate compound with NCS to catalyze the acetalization of aldehydes.

1H,1H,2H,2H-Tridecafluoro-1-n-octanol is a potent and selective halogenated hydrocarbon. It binds to DNA at the dinucleotide phosphate site, which is an important site for polymerase chain reaction (PCR) activation. 1HFN has been shown to be more effective than other halogenated hydrocarbons in vitro assays on rat liver microsomes. It has been used as an additive in wastewater treatment to remove organic contaminants and metal ions. In vivo studies have been carried out in CD-1 mice to determine the effects of 1HFN on the liver and kidneys; these studies showed no toxicological effects on these organs. 1HFN also has been shown to inhibit enzymes such as cytochrome P450 and monoamine oxidase B that are involved in drug metabolism and may lead to adverse reactions with drugs metabolized by these enzymes., 647-42-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 7748-36-9, formula is C3H6O2, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Synthetic Route of 7748-36-9

Lai, Junshan;Fianchini, Mauro;Pericas, Miquel A. research published 《 Development of Immobilized SPINOL-Derived Chiral Phosphoric Acids for Catalytic Continuous Flow Processes. Use in the Catalytic Desymmetrization of 3,3-Disubstituted Oxetanes》, the research content is summarized as follows. A family of C₂-sym. 1,1′-spirobiindane-7,7′-diol (SPINOL) derivatives containing polymerizable styryl units has been prepared through a highly convergent approach. Radical copolymerization of these monomers with styrene has allowed the synthesis of a family of immobilized SPINOL-derived chiral phosphoric acids (SPAs) where the combination of the restricted axial flexibility of the SPINOL units and the existence of extended and adaptable chiral walls adjacent to them leads to enhanced stereocontrol in catalytic processes. The optimal immobilized species (Cat f) brings about the catalytic desymmetrization of 3,3-disubstituted oxetanes in up to 90% yield with up to >99% enantioselectivity, exhibiting a very high recyclability (no decrease in conversion or enantioselectivity after 16, 16-h runs). To exploit these characteristics, a continuous flow process has been implemented and operated for the sequential preparation of 17 diverse enantioenriched products. The suitability of the flow setup for gram scale preparations (20 mmol scale), the stability of Cat f for long periods of time with intermittent use in flow, and its deactivation/reactivation by treatment with pyridine/hydrochloric acid in dioxane have been demonstrated. D. functional theory has been employed to provide a rational justification of the deep effect on enantioselectivity arising from the presence of sterically bulky substituents at the 6,6′-positions of the SPINOL unit. The main structural features of Cat f have subsequently been incorporated to the design of a simplified homogeneous analog available in a straightforward manner (Cat g) that performs the benchmark desymmetrization reaction with similar yields and enantioselectivities as Cat f, providing a convenient alternative for cases when single use in solution is sought.

Synthetic Route of 7748-36-9, Oxetan-3-ol is a useful research compound. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. The purity is usually 95%.
Oxetan-3-ol is a synthetic hydroxy compound with the chemical formula C6H12O3. It is an organic solvent that can be used in reactions involving vinyl alcohol and oxetane, such as ring-opening polymerization and cationic polymerization. Oxetan-3-ol has also been shown to react with ethyl bromoacetate to form the corresponding oxetane, which can be used as a bioisostere for chloropropane, a potential replacement for chlorofluorocarbons., 7748-36-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 527-07-1, formula is C6H11NaO7, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Synthetic Route of 527-07-1

Kurenkova, Anna Y.;Medvedeva, Tatiana B.;Gromov, Nikolay V.;Bukhtiyarov, Andrey V.;Gerasimov, Evgeny Y.;Cherepanova, Svetlana V.;Kozlova, Ekaterina A. research published 《 Sustainable hydrogen production from starch aqueous suspensions over a cadmium zinc sulfur-based photocatalyst》, the research content is summarized as follows. We explored the photoreforming of rice and corn starch with simultaneous hydrogen production over a Cd_0.7Zn_0.3S-based photocatalyst under visible light irradiation The photocatalyst was characterized by UV-vis diffuse reflectance spectroscopy, X-ray diffraction, and XPS. The influence of starch pretreatment conditions, such as hydrolysis temperature and alk. concentration, on the reaction rate was studied. The maximum rate of H₂ evolution was 730μmol·h^-1·g^-1, with AQE = 1.8% at 450 nm, in the solution obtained after starch hydrolysis in 5 M NaOH at 70°C. The composition of the aqueous phase of the suspension before and after the photocatalytic reaction was studied via high-performance liquid chromatog., and such products as glucose and sodium gluconate, acetate, formate, glycolate, and lactate were found after the photocatalytic reaction.

Synthetic Route of 527-07-1, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, 527-07-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 533-73-3, formula is C6H6O3, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Computed Properties of 533-73-3

Kundu, Kankana;Melsbach, Aileen;Heckel, Benjamin;Schneidemann, Sarah;Kanapathi, Dheeraj;Marozava, Sviatlana;Merl-Pham, Juliane;Elsner, Martin research published 《 Linking Increased Isotope Fractionation at Low Concentrations to Enzyme Activity Regulation: 4-Cl Phenol Degradation by Arthrobacter chlorophenolicus A6》, the research content is summarized as follows. Slow microbial degradation of organic trace chems. (“micropollutants”) has been attributed to either downregulation of enzymic turnover or rate-limiting substrate supply at low concentrations In previous biodegradation studies, a drastic decrease in isotope fractionation of atrazine revealed a transition from rate-limiting enzyme turnover to membrane permeation as a bottleneck when concentrations fell below the Monod constant of microbial growth. With degradation of the pollutant 4-chlorophenol (4-CP) by Arthrobacter chlorophenolicus A6, this study targeted a bacterium which adapts its enzyme activity to concentrations Unlike with atrazine degradation, isotope fractionation of 4-CP increased at lower concentrations, from ε(C) = -1.0 ± 0.5‰ in chemostats (D = 0.090 h^-1, 88 mg L^-1) and ε(C) = -2.1 ± 0.5‰ in batch (c₀ = 220 mg L^-1) to ε(C) = -4.1 ± 0.2‰ in chemostats at 90μg L^-1. Surprisingly, fatty acid composition indicated increased cell wall permeability at high concentrations, while proteomics revealed that catabolic enzymes (CphCI and CphCII) were differentially expressed at D = 0.090 h^-1. These observations support regulation on the enzyme activity level-through either a metabolic shift between catabolic pathways or decreased enzymic turnover at low concentrations-and, hence, reveal an alternative end-member scenario for bacterial adaptation at low concentrations Including more degrader strains into this multidisciplinary anal. approach offers the perspective to build a knowledge base on bottlenecks of bioremediation at low concentrations that considers bacterial adaptation.

533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Computed Properties of 533-73-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 141699-55-0, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 141699-55-0, name is tert-Butyl 3-hydroxyazetidine-1-carboxylate, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Kumura, Ko;Wakiyama, Yoshinari;Ueda, Kazutaka;Umemura, Eijiro;Watanabe, Takashi;Shitara, Eiki;Fushimi, Hideki;Yoshida, Takuji;Ajito, Keiichi research published 《 Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines》, the research content is summarized as follows. The synthesis and antibacterial activity of (7S)-7-sulfur-azetidin-3-yl lincomycin derivatives are described. Modification was achieved by a simple reaction of (7R)-7-O-methanesulfonyllincomycin and the corresponding substituted azetidine-2-thiol. Several compounds first showed moderate antibacterial activity against Streptococcus pneumoniae and Streptococcus pyogenes with erm gene as lincomycin derivatives

Related Products of 141699-55-0, Tert-butyl 3-hydroxyazetidine-1-carboxylate is a useful research compound. Its molecular formula is C8H15NO3 and its molecular weight is 173.21 g/mol. The purity is usually 95%.

Tert-butyl 3-hydroxyazetidine-1-carboxylate has been shown to be a good substrate for the preparation of N-protected amino alcohols and amines by the process of reductive amination. In this synthesis, tert-butyl azetidinium chloride is used as a catalyst in the reaction with sodium hydroxide. The tert-butyl group can be removed using ammonium hydroxide in the presence of a base such as triethylamine. This reaction can be performed on a large scale, making it useful in the manufacture of pharmaceuticals. The efficiency and solubility of this process make it suitable for use as an introduction to other processes involving N-protected amino alcohols or amines., 141699-55-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 533-73-3, formula is C6H6O3, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Recommanded Product: Benzene-1,2,4-triol

Kumar, Sonu;Kaushik, R. D.;Purohit, L. P. research published 《 Novel ZnO tetrapod-reduced graphene oxide nanocomposites for enhanced photocatalytic degradation of phenolic compounds and MB dye》, the research content is summarized as follows. In the present work, a bunch of ZnO tetrapod-reduced graphene oxide (ZTPG) nanocomposites (NCs) were synthesized via a simple and economical in-situ approach using high temperature refluxing method. The phase purity, morphol., optical and photocatalytic properties of NCs were studied comprehensively. Various weight percentage of rGO were proposed for efficient separation of electron hole pairs and improved photodegradation of phenolic compounds and methylene blue (MB) dye. The photocatalytic degradation of 4-chlorophenol (4-CP) and MB dye in aqueous system was performed for the assessment of photodegradation productivity of various ZTPG NCs with illumination of UV-light. The utmost mineralization after photodegradation attained about 94.8% for 4-CP over ZTPG-5 with UV-light exposure for 180 min. Similarly, the efficiency was also found 98.05% for MB dye photodegradation after 90 min UV-light introduction. The improved photocatalytic performance of ZTPG-5 NCs attributed to the enhanced adsorption capacity of 4-CP and MB dye over nanocomposite photocatalyst, effectual suppression of the recombination rate of electron hole pairs by synergistic influence among ZnO tetrapod and rGO sheet.

533-73-3, Benzene-1, 2, 4-triol, also known as hydroxyhydroquinone or 1, 2, 4-benzenetriol, belongs to the class of organic compounds known as hydroxyquinols and derivatives. Hydroxyquinols and derivatives are compounds containing a 1, 2, 4-trihydroxybenzene moiety. Benzene-1, 2, 4-triol is soluble (in water) and a very weakly acidic compound (based on its pKa). Outside of the human body, benzene-1, 2, 4-triol can be found in tea. This makes benzene-1, 2, 4-triol a potential biomarker for the consumption of this food product.
Benzene-1,2,4-triol is a benzenetriol carrying hydroxy groups at positions 1, 2 and 4. It has a role as a mouse metabolite.
1,2,4-Benzenetriol is a metabolite of benzene.
1,2,4-Benzenetriol is an intermediary metabolite of benzene that is present in roasted coffee beans. It is mutagenic and it causes cleaving of DNA single strands by the generation of reactive oxygen species.
1,2,4-Benzenetriol is a reactive molecule that has been shown to have hydrogen bonding interactions with copper chloride. It has been proposed as an inhibitor of methyltransferase, which is involved in the synthesis of methionine. Studies have shown that 1,2,4-Benzenetriol can also inhibit iron homeostasis and transfer reactions. The x-ray diffraction data for this compound shows that it forms a complex with the hydroxyl group. This complex is stabilized by hydrogen bonding interactions with the hydroxylic proton of the 1,2,4-benzenetriol molecule. 1,2,4-Benzenetriol has been shown to be toxic to HL-60 cells and K562 cells at concentrations greater than 5 mM. It has also been found to be effective against chlorogenic acids and other compounds in energy metabolism studies at concentrations between 0.5 and 2 mM., Recommanded Product: Benzene-1,2,4-triol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 24034-73-9, formula is C20H34O, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Synthetic Route of 24034-73-9

Kumar, Sarma Rajeev;Rai, Avanish;Bomzan, Dikki Pedenla;Kumar, Krishna;Hemmerlin, Andrea;Dwivedi, Varun;Godbole, Rucha C.;Barvkar, Vitthal;Shanker, Karuna;Shilpashree, H. B.;Bhattacharya, Ankita;Smitha, Attibele Ramamurthy;Hegde, Namratha;Nagegowda, Dinesh A. research published 《 A plastid-localized bona fide geranylgeranyl diphosphate synthase plays a necessary role in monoterpene indole alkaloid biosynthesis in Catharanthus roseus》, the research content is summarized as follows. In plants, geranylgeranyl diphosphate (GGPP, C₂₀) synthesized by GGPP synthase (GGPPS) serves as precursor for vital metabolic branches including specialized metabolites. Here, we report the characterization of a GGPPS (CrGGPPS2) from the Madagascar periwinkle (Catharanthus roseus) and demonstrate its role in monoterpene (C₁₀)-indole alkaloids (MIA) biosynthesis. The expression of CrGGPPS2 was not induced in response to Me jasmonate (MeJA), and was similar to the gene encoding type-I protein geranylgeranyltransferase_β subunit (CrPGGT-I_β), which modulates MIA formation in C. roseus cell cultures. Recombinant CrGGPPS2 exhibited a bona fide GGPPS activity by catalyzing the formation of GGPP as the sole product. Co-localization of fluorescent protein fusions clearly showed CrGGPPS2 was targeted to plastids. Downregulation of CrGGPPS2 by virus-induced gene silencing (VIGS) significantly decreased the expression of transcription factors and pathway genes related to MIA biosynthesis, resulting in reduced MIA. Chem. complementation of CrGGPPS2-vigs leaves with geranylgeraniol (GGol, alc. form of GGPP) restored the neg. effects of CrGGPPS2 silencing on MIA biosynthesis. In contrast to VIGS, transient and stable overexpression of CrGGPPS2 enhanced the MIA biosynthesis. Interestingly, VIGS and transgenic-overexpression of CrGGPPS2 had no effect on the main GGPP-derived metabolites, cholorophylls and carotenoids in C. roseus leaves. Moreover, silencing of CrPGGT-I_β, similar to CrGGPPS2-vigs, neg. affected the genes related to MIA biosynthesis resulting in reduced MIA. Overall, this study demonstrated that plastidial CrGGPPS2 plays an indirect but necessary role in MIA biosynthesis. We propose that CrGGPPS2 might be involved in providing GGPP for modifying proteins of the signaling pathway involved in MIA biosynthesis.

24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, Synthetic Route of 24034-73-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 527-07-1, formula is C6H11NaO7, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Formula: C6H11NaO7

Kumar, Abhinash;Jha, Manindra Nath;Singh, Devendra;Pathak, Devashish;Rajawat, Mahendra Vikram Singh research published 《 Prospecting catabolic diversity of microbial strains for developing microbial consortia and their synergistic effect on Lentil (Lensesculenta) growth, yield and iron biofortification》, the research content is summarized as follows. Carbon profiling of heterotrophic microbial inoculants is worthwhile strategy for formulating consortium-based biofertilizers. Consortium-based biofertilizers are better than single strain-based biofertilizers for sustaining agricultural productivity and enhancing micronutrient concentration in grains. Currently, we investigated catabolic diversity among microbes using different carbon sources and certain enzyme activities. A field experiment was also carried to evaluate the synergistic effect of selected lentil Rhizobia and plant growth promoting rhizobacteria strains on lentil growth, yield, nitrogen fixation, and Fe-content in seeds. On the basis of carbon profiling Bacillus sp.RB1 and Pseudomonas sp.RP1 were selected for synergistic study with lentil Rhizobium-Rhizobium leguminosarum subsp. viciae RR1. Co-inoculation of Rhizobium with Bacillus sp.RB1 and Pseudomonas sp.RP1 significantly enhanced the plant height, number of pods per plant, seed yield, number of nodules per plant, nitrogenase activity and Fe biofortification in seed over the single Rhizobium inoculation or dual combination of Rhizobium + RB1 or RP1. The response of single Rhizobium inoculation or co-inoculation of Rhizobium with RB1 and/or RP1 at 50% RDF was almost similar or higher than full dose of recommended N:P:K with respect to lentil yield and Fe biofortification in seed. This deciphered grouping of microbial strains for formulation of microbial consortia-based biofertilizers and revealed the promise of consortium of Rhizobium and plant growth promoting rhizobacteria in improving the biol. yield and enhancing the Fe content of lentil seed.

Formula: C6H11NaO7, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, 527-07-1.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Some low molecular weight alcohols of industrial importance are produced by the addition of water to alkenes. 24034-73-9, formula is C20H34O, Ethanol, isopropanol, 2-butanol, and tert-butanol are produced by this general method. Two implementations are employed, the direct and indirect methods. Quality Control of 24034-73-9

Kumar Paul, Gobindo;Mahmud, Shafi;Aldahish, Afaf A.;Afroze, Mirola;Biswas, Suvro;Briti Ray Gupta, Swagota;Hasan Razu, Mahmudul;Zaman, Shahriar;Salah Uddin, Md.;Nahari, Mohammed H.;Merae Alshahrani, Mohammed;Abdul Rahman Alshahrani, Mohammed;Khan, Mala;Abu Saleh, Md. research published 《 Computational screening and biochemical analysis of Pistacia integerrima and Pandanus odorifer plants to find effective inhibitors against Receptor-Binding domain (RBD) of the spike protein of SARS-Cov-2》, the research content is summarized as follows. Although World Health Organization-approved emergency vaccines are available in many countries, the mortality rate from COVID-19 remains high due to the fourth or fifth wave and the delta variant of the coronavirus. Thus, an effective mechanistic investigation in treating this disease is urgently needed. In this work, we extracted phytochems. from two mangrove plants, Pistacia integerrima and Pandanus odorifer, assessing their potential actions against the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2. The antioxidant activities of Pistacia integerrima leaves and fruits were 142.10 and 97.13 μg/mL, resp., whereas Pandanus odorifer leaves and fruits were 112.50 and 292.71 μg/mL, resp. Furthermore, leaf extracts from both plants had lower cytotoxicity against Artemia salina than fruit extracts Gas chromatog.-mass spectrometry anal. revealed a total of 145 potential phytochems. from these extracts Three phytochems., 28-demethyl-beta-amyrone, 24-Noroleana-3,12-diene, and stigmasterol, displayed binding free energy values of – 8.3, -7.5, and – 8.1 Kcal/mol, resp., in complexes with the spike protein of SARS-CoV-2. The root-mean-square deviation, solvent-accessible surface area, radius of gyration, root-mean-square fluctuations, and hydrogen bonds were used to ensure the binding stability of the docked complexes in the atomistic simulation. Thus, wet-lab validations are necessary to support these findings.

Quality Control of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of 24034-73-9, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 24034-73-9, name is (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Kruk, Jerzy;Gabruk, Michal;Kryszczak, Marian;Wasik, Piotr research published 《 Protochlorophylls in Cucurbitaceae – Distribution, biosynthesis and phylogeny》, the research content is summarized as follows. Using high-resolution chromatog. we resolved monovinyl (MV)- and divinyl (DV)-protochlorophylls (Pchls) and detected all of their side-chain homologues in the inner seed coat of Cucurbita maxima, C. pepo and their varieties. Furthermore, we analyzed other less common representatives of the Cucurbitaceae family that were found to accumulate mostly MV-Pchls. All these species and varieties showed the characteristic composition of individual Pchls. Addnl., we also detected all of the corresponding protopheophytins, which accounted for between 1.1 and 35.5% of Pchls and are supposed to be degradation products of Pchls, formed during seed storage. A pigment composition anal. of C. maxima seedlings performed during deetiolation revealed that chlorophyll (Chl) a content increased gradually, while the levels of Pchl-GG and Chl-GG, a precursor of Chl a, were low and did not change significantly. However, when the seedlings were incubated with the precursor of tetrapyrrole biosynthesis (δ-aminolevulinic acid) before illumination, the Chl-GG content increased dramatically, while synthesis of Chl a was inhibited. These data indicate that in C. maxima seedlings, Chl a is not synthesized from geranylgeranyl-pyrophoshate via Chl-GG, but rather directly from phytyl-pyrophosphate. Phylogenetic anal. of Chl synthase genes revealed that many species, including those of the Cucurbitaceae family, have two or more Chl synthase genes. This suggests that these addnl. genes, at least in some species, might encode isoforms involved in Pchl synthesis.

Electric Literature of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
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Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts